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Volumn 73, Issue 4, 2013, Pages 1328-1339

Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; BUNGAROTOXIN RECEPTOR; CASPASE 3; CHOLINE ACETYLTRANSFERASE; CHOLINE TRANSPORTER 1; CHOLINERGIC RECEPTOR; EPIDERMAL GROWTH FACTOR; MEMBRANE PROTEIN; NICOTINE; NICOTINIC RECEPTOR ALPHA3BETA2; NICOTINIC RECEPTOR BETA3; PROTEIN KINASE B; SMALL INTERFERING RNA; SOMATOMEDIN B; UNCLASSIFIED DRUG; VESAMICOL; VESICULAR ACETYLCHOLINE TRANSPORTER;

EID: 84874296019     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3190     Document Type: Article
Times cited : (27)

References (48)
  • 1
    • 77958608449 scopus 로고    scopus 로고
    • Systemic approaches for multifocal bronchioloalveolar carcinoma: Is there an appropriate target?
    • Levy BP, Drilon A, Makarian L, Patel AA, Grossbard ML. Systemic approaches for multifocal bronchioloalveolar carcinoma: is there an appropriate target? Oncology (Williston Park) 2010;24:888-98, 900.
    • (2010) Oncology (Williston Park) , vol.24 , Issue.900 , pp. 888-98
    • Levy, B.P.1    Drilon, A.2    Makarian, L.3    Patel, A.A.4    Grossbard, M.L.5
  • 2
  • 4
    • 77955095701 scopus 로고    scopus 로고
    • Clinical features of bronchioloalveolar carcinoma with new histologic and staging definitions
    • Ebbert JO, Chhatwani L, Aubry MC, Wampfler J, Stoddard S, Zhang F, et al. Clinical features of bronchioloalveolar carcinoma with new histologic and staging definitions. J Thorac Oncol 2010;5:1213-20.
    • (2010) J Thorac Oncol , vol.5 , pp. 1213-20
    • Ebbert, J.O.1    Chhatwani, L.2    Aubry, M.C.3    Wampfler, J.4    Stoddard, S.5    Zhang, F.6
  • 5
    • 84874300679 scopus 로고    scopus 로고
    • The Health Consequences of Smoking. A report of the Surgeon General's Office on Smoking and Health, DHHS, Washington DC. 2004
    • The Health Consequences of Smoking. A report of the Surgeon General's Office on Smoking and Health, DHHS, Washington DC. 2004.
  • 6
    • 13244296625 scopus 로고    scopus 로고
    • Cancer IARC In: Tobacco Smoke And Involuntary Smoking. Lyon France: IARC
    • Cancer IARC. IARC Monographs on the evaluation of carcinogenic risks to humans. In: Tobacco smoke and involuntary smoking. Lyon, France: IARC; 2004. p. 51-1187.
    • (2004) IARC Monographs On The Evaluation Of Carcinogenic Risks To Humans , pp. 51-1187
  • 7
    • 77449158903 scopus 로고    scopus 로고
    • Mucinous and nonmucinous bronchioloalveolar carcinoma and smoking
    • Garfield D. Mucinous and nonmucinous bronchioloalveolar carcinoma and smoking. Am J Clin Pathol 2010;133:341-2.
    • (2010) Am J Clin Pathol , vol.133 , pp. 3412
    • Garfield, D.1
  • 8
    • 78751591728 scopus 로고    scopus 로고
    • Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: Pooled analysis of seven case-control studies in the international lung cancer consortium (ilcco)
    • Boffetta P, Jayaprakash V, Yang P, Asomaning K, Muscat JE, Schwartz AG, et al. Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO). Cancer Causes Control 2011;22:73-9.
    • (2011) Cancer Causes Control , vol.22 , pp. 739
    • Boffetta, P.1    Jayaprakash, V.2    Yang, P.3    Asomaning, K.4    Muscat, J.E.5    Schwartz, A.G.6
  • 9
    • 12744260986 scopus 로고    scopus 로고
    • Bronchoalveolar carcinoma (bac) of the lung is related to cigarette smoking: A case-control study from rhode island (ri)
    • abstr 2711)
    • Rolen KA, Fulton JPT, D. J., Strauss GM. Bronchoalveolar carcinoma (BAC) of the lung is related to cigarette smoking: a case-control study from Rhode Island (RI). Proc Am Soc Clin Oncol 22: 2003 (abstr 2711).
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Rolen, K.A.1    Fulton, J.P.T.D.J.2    Strauss, G.M.3
  • 10
    • 0026558330 scopus 로고
    • Relation of bronchioloalveolar carcinoma to tobacco
    • Morabia A, Wynder EL. Relation of bronchioloalveolar carcinoma to tobacco. BMJ 1992;304:541-3.
    • (1992) BMJ , vol.304 , pp. 5413
    • Morabia, A.1    Wynder, E.L.2
  • 11
    • 65349167234 scopus 로고    scopus 로고
    • Egfr and k-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to egfr inhibitors
    • Sartori G, Cavazza A, Sgambato A, Marchioni A, Barbieri F, Longo L, et al. EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors. Am J Clin Pathol 2009;131:478-89.
    • (2009) Am J Clin Pathol , vol.131 , pp. 478-89
    • Sartori, G.1    Cavazza, A.2    Sgambato, A.3    Marchioni, A.4    Barbieri, F.5    Longo, L.6
  • 12
    • 79959222735 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor signaling in tumor growth and metastasis
    • Singh S, Pillai S, Chellappan S. Nicotinic acetylcholine receptor signaling in tumor growth and metastasis. J Oncol 2011;2011:456743.
    • (2011) J Oncol , vol.2011 , pp. 456743
    • Singh, S.1    Pillai, S.2    Chellappan, S.3
  • 14
    • 40549083717 scopus 로고    scopus 로고
    • Basic and clinical aspects of non-neuronal acetylcholine: Expression of non-neuronal acetylcholine in lung cancer provides a new target for cancer therapy
    • Song P, Spindel ER. Basic and clinical aspects of non-neuronal acetylcholine: expression of non-neuronal acetylcholine in lung cancer provides a new target for cancer therapy. J Pharmacol Sci 2008;106: 180-5.
    • (2008) J Pharmacol Sci , vol.106 , pp. 1805
    • Song, P.1    Spindel, E.R.2
  • 15
    • 49649125178 scopus 로고    scopus 로고
    • Activated cholinergic signaling provides a target in squamous cell lung carcinoma
    • Song P, Sekhon HS, Fu XW, Maier M, Jia Y, Duan J, et al. Activated cholinergic signaling provides a target in squamous cell lung carcinoma. Cancer Res 2008;68:4693-700.
    • (2008) Cancer Res , vol.68 , pp. 4693-700
    • Song, P.1    Sekhon, H.S.2    Fu, X.W.3    Maier, M.4    Jia, Y.5    Duan, J.6
  • 16
    • 0037229715 scopus 로고    scopus 로고
    • Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma
    • Song P, Sekhon HS, Jia Y, Keller JA, Blusztajn JK, Mark GP, et al. Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma. Cancer Res 2003;63:214-21. (Pubitemid 36070442)
    • (2003) Cancer Research , vol.63 , Issue.1 , pp. 214-221
    • Song, P.1    Sekhon, H.S.2    Jia, Y.3    Keller, J.A.4    Blusztajn, J.K.5    Mark, G.P.6    Spindel, E.R.7
  • 18
    • 34248597724 scopus 로고    scopus 로고
    • M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion
    • DOI 10.1158/0008-5472.CAN-06-2484
    • Song P, Sekhon HS, Lu A, Arredondo J, Sauer D, Gravett C, et al. M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion. Cancer Res 2007;67: 3936-44. (Pubitemid 46762183)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3936-3944
    • Song, P.1    Sekhon, H.S.2    Lu, A.3    Arredondo, J.4    Sauer, D.5    Gravett, C.6    Mark, G.P.7    Grando, S.A.8    Spindel, E.R.9
  • 19
    • 79951923011 scopus 로고    scopus 로고
    • Arrb1-mediated regulation of e2f target genes in nicotine-induced growth of lung tumors
    • Dasgupta P, Rizwani W, Pillai S, Davis R, Banerjee S, Hug K, et al. ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors. J Natl Cancer Inst 2011;103:317-33.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 317-33
    • Dasgupta, P.1    Rizwani, W.2    Pillai, S.3    Davis, R.4    Banerjee, S.5    Hug, K.6
  • 20
    • 84861540638 scopus 로고    scopus 로고
    • Mg624, an alpha7-nachr antagonist, inhibits angiogenesis via the egr-1/fgf2 pathway
    • Brown KC, Lau JK, Dom AM, Witte TR, Luo H, Crabtree CM, et al. MG624, an alpha7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway. Angiogenesis 2012;15:99-114.
    • (2012) Angiogenesis , vol.15 , pp. 99-114
    • Brown, K.C.1    Lau, J.K.2    Dom, A.M.3    Witte, T.R.4    Luo, H.5    Crabtree, C.M.6
  • 21
    • 77956314277 scopus 로고    scopus 로고
    • Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the e2f pathway
    • Brown KC, Witte TR, Hardman WE, Luo H, Chen YC, Carpenter AB, et al. Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway. PLoS One 2010;5:e10243.
    • (2010) PLoS One , vol.5
    • Brown, K.C.1    Witte, T.R.2    Hardman, W.E.3    Luo, H.4    Chen, Y.C.5    Carpenter, A.B.6
  • 22
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • DOI 10.1007/BF00300234
    • Tomayko MM, Reynolds CP. Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother Pharmacol 1989;24: 148-54. (Pubitemid 19163397)
    • (1989) Cancer Chemotherapy and Pharmacology , vol.24 , Issue.3 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 24
    • 45549105690 scopus 로고    scopus 로고
    • A small molecule disruptor of rb/raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice
    • Kinkade R, Dasgupta P, Carie A, Pernazza D, Carless M, Pillai S, et al. A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice. Cancer Res 2008;68:3810-8.
    • (2008) Cancer Res , vol.68 , pp. 38108
    • Kinkade, R.1    Dasgupta, P.2    Carie, A.3    Pernazza, D.4    Carless, M.5    Pillai, S.6
  • 25
    • 0029421084 scopus 로고
    • Human and monkey cholinergic neurons visualized in paraffin-embedded tissues by immunoreactivity for vacht, the vesicular acetylcholine transporter
    • Schafer MK, Weihe E, Erickson JD, Eiden LE. Human and monkey cholinergic neurons visualized in paraffin-embedded tissues by immunoreactivity for VAChT, the vesicular acetylcholine transporter. J Mol Neurosci 1995;6:225-35.
    • (1995) J Mol Neurosci , vol.6 , pp. 225-35
    • Schafer, M.K.1    Weihe, E.2    Erickson, J.D.3    Eiden, L.E.4
  • 27
    • 0032917985 scopus 로고    scopus 로고
    • Cholinergic neurons of the pelvic autonomic ganglia and uterus of the female rat: Distribution of axons and presence of muscarinic receptors
    • DOI 10.1007/s004410051290
    • Papka RE, Traurig HH, Schemann M, Collins J, Copelin T, Wilson K. Cholinergic neurons of the pelvic autonomic ganglia and uterus of the female rat: distribution of axons and presence of muscarinic receptors. Cell Tissue Res 1999;296:293-305. (Pubitemid 29219181)
    • (1999) Cell and Tissue Research , vol.296 , Issue.2 , pp. 293-305
    • Papka, R.E.1    Traurig, H.H.2    Schemann, M.3    Collins, J.4    Copelin, T.5    Wilson, K.6
  • 28
    • 33846907877 scopus 로고    scopus 로고
    • Transient suppression of the vesicular acetylcholine transporter in urinary bladder pathways following spinal cord injury
    • Takahara Y, Maeda M, Nakatani T, Kiyama H. Transient suppression of the vesicular acetylcholine transporter in urinary bladder pathways following spinal cord injury. Brain Res 2007;1137:20-8.
    • (2007) Brain Res , vol.1137 , pp. 208
    • Takahara, Y.1    Maeda, M.2    Nakatani, T.3    Kiyama, H.4
  • 29
    • 0034922748 scopus 로고    scopus 로고
    • Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis
    • Heeschen C, Jang JJ, Weis M, Pathak A, Kaji S, Hu RS, et al. Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis. Nat Med 2001;7:833-9.
    • (2001) Nat Med , vol.7 , pp. 8339
    • Heeschen, C.1    Jang, J.J.2    Weis, M.3    Pathak, A.4    Kaji, S.5    Hu, R.S.6
  • 30
    • 63049100044 scopus 로고    scopus 로고
    • Functional selectivity of egf family peptide growth factors: Implications for cancer
    • Wilson KJ, Gilmore JL, Foley J, Lemmon MA, Riese DJ II. Functional selectivity of EGF family peptide growth factors: implications for cancer. Pharmacol Ther 2009;122:1-8.
    • (2009) Pharmacol Ther , vol.122 , pp. 18
    • Wilson, K.J.1    Gilmore, J.L.2    Foley, J.3    Lemmon, M.A.4    Riese II, D.J.5
  • 31
    • 0023235725 scopus 로고
    • Detection of human lung epithelial cell growth factors produced by a lung carcinoma cell line: Use in culture of primary solid lung tumors
    • Siegfried JM. Detection of human lung epithelial cell growth factors produced by a lung carcinoma cell line: use in culture of primary solid lung tumors. Cancer Res 1987;47:2903-10. (Pubitemid 17113434)
    • (1987) Cancer Research , vol.47 , Issue.11 , pp. 2903-2910
    • Siegfried, J.M.1
  • 34
    • 70349462997 scopus 로고    scopus 로고
    • The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancers
    • Camidge DR, Dziadziuszko R, Hirsch FR. The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancers. Clin Lung Cancer 2009;10:262-72.
    • (2009) Clin Lung Cancer , vol.10 , pp. 262-72
    • Camidge, D.R.1    Dziadziuszko, R.2    Hirsch, F.R.3
  • 36
    • 0022486121 scopus 로고
    • Acetylcholine transport and drug inhibition kinetics in torpedo synaptic vesicles
    • Bahr BA, Parsons SM. Acetylcholine transport and drug inhibition kinetics in Torpedo synaptic vesicles. J Neurochem 1986;46:1214-8.
    • (1986) J Neurochem , vol.46 , pp. 12148
    • Bahr, B.A.1    Parsons, S.M.2
  • 37
    • 0033603597 scopus 로고    scopus 로고
    • Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells
    • Wilke RA, Mehta RP, Lupardus PJ, Chen Y, Ruoho AE, Jackson MB. Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells. J Biol Chem 1999;274: 18387-92.
    • (1999) J Biol Chem , vol.274 , pp. 18387-92
    • Wilke, R.A.1    Mehta, R.P.2    Lupardus, P.J.3    Chen, Y.4    Ruoho, A.E.5    Jackson, M.B.6
  • 38
    • 0028965077 scopus 로고
    • Vesamicol analogues as sigma ligands. molecular determinants of selectivity at the vesamicol receptor
    • Efange SM, Mach RH, Smith CR, Khare AB, Foulon C, Akella SK, et al. Vesamicol analogues as sigma ligands. Molecular determinants of selectivity at the vesamicol receptor. Biochem Pharmacol 1995;49: 791-7.
    • (1995) Biochem Pharmacol , vol.49 , pp. 7917
    • Efange, S.M.1    Mach, R.H.2    Smith, C.R.3    Khare, A.B.4    Foulon, C.5    Akella, S.K.6
  • 39
    • 0031834224 scopus 로고    scopus 로고
    • Tobacco and lung cancer
    • Johnson BE. Tobacco and lung cancer. Prim Care 1998;25:279-91.
    • (1998) Prim Care , vol.25 , pp. 279-91
    • Johnson, B.E.1
  • 40
    • 0030832209 scopus 로고    scopus 로고
    • Second lung cancers in patients successfully treated for lung cancer
    • Johnson BE, Cortazar P, Chute JP. Second lung cancers in patients successfully treated for lung cancer. Semin Oncol 1997;24:492-9.
    • (1997) Semin Oncol , vol.24 , pp. 4929
    • Johnson, B.E.1    Cortazar, P.2    Chute, J.P.3
  • 42
    • 71049136859 scopus 로고    scopus 로고
    • Evaluation of radioiodinated vesamicol analogs for sigma receptor imaging in tumor and radionuclide receptor therapy
    • Ogawa K, Shiba K, Akhter N, Yoshimoto M, Washiyama K, Kinuya S, et al. Evaluation of radioiodinated vesamicol analogs for sigma receptor imaging in tumor and radionuclide receptor therapy. Cancer Sci 2009;100:2188-92.
    • (2009) Cancer Sci , vol.100 , pp. 2188-92
    • Ogawa, K.1    Shiba, K.2    Akhter, N.3    Yoshimoto, M.4    Washiyama, K.5    Kinuya, S.6
  • 43
    • 84874315892 scopus 로고    scopus 로고
    • Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
    • Ogawa K, Kanbara H, Shiba K, Kitamura Y, Kozaka T, Kiwada T, et al. Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent. EJNMMI Res 2012;2:54.
    • (2012) EJNMMI Res , vol.2 , pp. 54
    • Ogawa, K.1    Kanbara, H.2    Shiba, K.3    Kitamura, Y.4    Kozaka, T.5    Kiwada, T.6
  • 45
    • 1642434133 scopus 로고    scopus 로고
    • Tobacco Carcinogen-Induced Cellular Transformation Increases Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Vitro and in Vivo
    • DOI 10.1158/0008-5472.CAN-03-3241
    • West KA, Linnoila IR, Belinsky SA, Harris CC, Dennis PA. Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 30-kinase/Akt pathway in vitro and in vivo. Cancer Res 2004;64:446-51. (Pubitemid 38120880)
    • (2004) Cancer Research , vol.64 , Issue.2 , pp. 446-451
    • West, K.A.1    Linnoila, I.R.2    Belinsky, S.A.3    Harris, C.C.4    Dennis, P.A.5
  • 46
    • 24744442131 scopus 로고    scopus 로고
    • Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells
    • DOI 10.1016/j.lungcan.2005.05.005, PII S0169500205002448
    • Kitazaki T, Soda H, Doi S, Nakano H, Nakamura Y, Kohno S. Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells. Lung Cancer 2005;50:19-24. (Pubitemid 41297465)
    • (2005) Lung Cancer , vol.50 , Issue.1 , pp. 19-24
    • Kitazaki, T.1    Soda, H.2    Doi, S.3    Nakano, H.4    Nakamura, Y.5    Kohno, S.6
  • 47
    • 69449106495 scopus 로고    scopus 로고
    • Roles of mkk1/2-erk1/2 and phosphoinositide 3-kinase-akt signaling pathways in erlotinib-induced rad51 suppression and cytotoxicity in human non-small cell lung cancer cells
    • Ko JC, Ciou SC, Jhan JY, Cheng CM, Su YJ, Chuang SM, et al. Roles of MKK1/2-ERK1/2 and phosphoinositide 3-kinase-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells. Mol Cancer Res 2009;7: 1378-89.
    • (2009) Mol Cancer Res , vol.7 , pp. 1378-89
    • Ko, J.C.1    Ciou, S.C.2    Jhan, J.Y.3    Cheng, C.M.4    Su, Y.J.5    Chuang, S.M.6
  • 48
    • 27544505166 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase/akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo
    • Denlinger CE, Rundall BK, Jones DR. Inhibition of phosphatidylinositol 3-kinase/Akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo. J Thorac Cardiovasc Surg 2005;130:1422-9.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 14229
    • Denlinger, C.E.1    Rundall, B.K.2    Jones, D.R.3


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