-
1
-
-
84872936239
-
Pharmacogenomics of adverse drug reactions
-
3707028 1:CAS:528:DC%2BC3sXis1yktL4%3D 23360680
-
Daly AK. Pharmacogenomics of adverse drug reactions. Genome Med. 2013;5(1):5.
-
(2013)
Genome Med.
, vol.5
, Issue.1
, pp. 5
-
-
Daly, A.K.1
-
2
-
-
84880479910
-
Mobilizing pharmacogenomic analyses during clinical trials in drug development
-
23859576
-
Bienfait KL, Shaw PM, Murthy G, Warner AW. Mobilizing pharmacogenomic analyses during clinical trials in drug development. Pharmacogenomics. 2013;14(10):1227-35.
-
(2013)
Pharmacogenomics.
, vol.14
, Issue.10
, pp. 1227-1235
-
-
Bienfait, K.L.1
Shaw, P.M.2
Murthy, G.3
Warner, A.W.4
-
3
-
-
3042723720
-
Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18,820 patients
-
443443 15231615
-
Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ. 2004;329(7456):15-9.
-
(2004)
BMJ.
, vol.329
, Issue.7456
, pp. 15-19
-
-
Pirmohamed, M.1
James, S.2
Meakin, S.3
Green, C.4
Scott, A.K.5
Walley, T.J.6
-
4
-
-
78751584806
-
Incidence of adverse drug events and medication errors in Japan: The JADE study
-
3019321 20872082
-
Morimoto T, Sakuma M, Matsui K, Kuramoto N, Toshiro J, Murakami J, et al. Incidence of adverse drug events and medication errors in Japan: the JADE study. J Gen Intern Med. 2011;26(2):148-53.
-
(2011)
J Gen Intern Med.
, vol.26
, Issue.2
, pp. 148-153
-
-
Morimoto, T.1
Sakuma, M.2
Matsui, K.3
Kuramoto, N.4
Toshiro, J.5
Murakami, J.6
-
5
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
-
9555760
-
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279(15):1200-5.
-
(1998)
JAMA.
, vol.279
, Issue.15
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
6
-
-
0037421590
-
Pharmacogenomics-drug disposition, drug targets, and side effects
-
12571262
-
Evans WE, McLeod HL. Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med. 2003;348(6):538-49.
-
(2003)
N Engl J Med.
, vol.348
, Issue.6
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
7
-
-
0035861049
-
Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
-
11710893
-
Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA. 2001;286(18):2270-9.
-
(2001)
JAMA.
, vol.286
, Issue.18
, pp. 2270-2279
-
-
Phillips, K.A.1
Veenstra, D.L.2
Oren, E.3
Lee, J.K.4
Sadee, W.5
-
8
-
-
0034638766
-
Pharmacogenetics and adverse drug reactions
-
11089838
-
Meyer UA. Pharmacogenetics and adverse drug reactions. Lancet. 2000;356(9242):1667-71.
-
(2000)
Lancet.
, vol.356
, Issue.9242
, pp. 1667-1671
-
-
Meyer, U.A.1
-
9
-
-
0000197885
-
The hemolytic effect of primaquine and related compounds: A review
-
13618370
-
Beutler E. The hemolytic effect of primaquine and related compounds: a review. Blood. 1959;14(2):103-39.
-
(1959)
Blood.
, vol.14
, Issue.2
, pp. 103-139
-
-
Beutler, E.1
-
10
-
-
0026000701
-
The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26
-
1769657
-
Allderdice PW, Gardner HA, Galutira D, Lockridge O, LaDu BN, McAlpine PJ. The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26. Genomics. 1991;11(2):452-4.
-
(1991)
Genomics.
, vol.11
, Issue.2
, pp. 452-454
-
-
Allderdice, P.W.1
Gardner, H.A.2
Galutira, D.3
Lockridge, O.4
Ladu, B.N.5
McAlpine, P.J.6
-
11
-
-
84865516911
-
HLA and pharmacogenetics of drug hypersensitivity
-
22920398
-
Pavlos R, Mallal S, Phillips E. HLA and pharmacogenetics of drug hypersensitivity. Pharmacogenomics. 2012;13(11):1285-306.
-
(2012)
Pharmacogenomics.
, vol.13
, Issue.11
, pp. 1285-1306
-
-
Pavlos, R.1
Mallal, S.2
Phillips, E.3
-
12
-
-
84872899545
-
Pharmacogenomics of drug-metabolizing enzymes: A recent update on clinical implications and endogenous effects
-
23089672
-
Sim SC, Kacevska M, Ingelman-Sundberg M. Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects. Pharmacogenomics J. 2013;13(1):1-11.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.1
, pp. 1-11
-
-
Sim, S.C.1
Kacevska, M.2
Ingelman-Sundberg, M.3
-
13
-
-
77649216536
-
Membrane transporters in drug development
-
International Transporter C
-
International Transporter C, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, et al. Membrane transporters in drug development. Nat Rev Drug Discov. 2010;9(3):215-36.
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.3
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
-
14
-
-
79955492923
-
Pharmacogenomics: The genetics of variable drug responses
-
3093198 21502584
-
Roden DM, Wilke RA, Kroemer HK, Stein CM. Pharmacogenomics: the genetics of variable drug responses. Circulation. 2011;123(15):1661-70.
-
(2011)
Circulation.
, vol.123
, Issue.15
, pp. 1661-1670
-
-
Roden, D.M.1
Wilke, R.A.2
Kroemer, H.K.3
Stein, C.M.4
-
15
-
-
0034978572
-
The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
-
11434505
-
van der Weide J, Steijns LS, van Weelden MJ, de Haan K. The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. Pharmacogenetics. 2001;11(4):287-91.
-
(2001)
Pharmacogenetics.
, vol.11
, Issue.4
, pp. 287-291
-
-
Van Der Weide, J.1
Steijns, L.S.2
Van Weelden, M.J.3
De Haan, K.4
-
16
-
-
79955754985
-
CYP2C9 polymorphism in patients with epilepsy: Genotypic frequency analyzes and phenytoin adverse reactions correlation
-
21537551
-
Twardowschy CA, Werneck LC, Scola RH, De Paola L, Silvado CE. CYP2C9 polymorphism in patients with epilepsy: genotypic frequency analyzes and phenytoin adverse reactions correlation. Arquivos de neuro-psiquiatria. 2011;69(2A):153-8.
-
(2011)
Arquivos de Neuro-psiquiatria.
, vol.69
, Issue.2 A
, pp. 153-158
-
-
Twardowschy, C.A.1
Werneck, L.C.2
Scola, R.H.3
De Paola, L.4
Silvado, C.E.5
-
17
-
-
52649159919
-
Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy
-
18756910
-
Samardzija M, Topic E, Stefanovic M, Zibar L, Samardzija G, Balen S, et al. Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy. Coll Antropol. 2008;32(2):557-64.
-
(2008)
Coll Antropol.
, vol.32
, Issue.2
, pp. 557-564
-
-
Samardzija, M.1
Topic, E.2
Stefanovic, M.3
Zibar, L.4
Samardzija, G.5
Balen, S.6
-
18
-
-
34249728419
-
Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting
-
17562299
-
Lee SY, Lee ST, Kim JW. Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting. J Biochem Mol Biol. 2007;40(3):448-52.
-
(2007)
J Biochem Mol Biol.
, vol.40
, Issue.3
, pp. 448-452
-
-
Lee, S.Y.1
Lee, S.T.2
Kim, J.W.3
-
19
-
-
10744225344
-
Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use
-
1574205 1:CAS:528:DC%2BD2cXhsFOis7w%3D 14707031
-
Martinez C, Blanco G, Ladero JM, Garcia-Martin E, Taxonera C, Gamito FG, et al. Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use. Br J Pharmacol. 2004;141(2):205-8.
-
(2004)
Br J Pharmacol.
, vol.141
, Issue.2
, pp. 205-208
-
-
Martinez, C.1
Blanco, G.2
Ladero, J.M.3
Garcia-Martin, E.4
Taxonera, C.5
Gamito, F.G.6
-
20
-
-
0034792584
-
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
-
2014584 1:CAS:528:DC%2BD3MXnvVans7k%3D 11678778
-
Goldstein JA. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol. 2001;52(4):349-55.
-
(2001)
Br J Clin Pharmacol.
, vol.52
, Issue.4
, pp. 349-355
-
-
Goldstein, J.A.1
-
21
-
-
0242543259
-
Clinical relevance of genetic polymorphisms in the human CYP2C9 gene
-
14641553
-
Schwarz UI. Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. Eur J Clin Invest. 2003;33(Suppl 2):23-30.
-
(2003)
Eur J Clin Invest.
, vol.33
, pp. 23-30
-
-
Schwarz, U.I.1
-
22
-
-
84870002919
-
Current status of clopidogrel pharmacogenomics
-
23171330
-
Giusti B, Gori AM, Marcucci R, Abbate R. Current status of clopidogrel pharmacogenomics. Pharmacogenomics. 2012;13(15):1671-4.
-
(2012)
Pharmacogenomics.
, vol.13
, Issue.15
, pp. 1671-1674
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
Abbate, R.4
-
23
-
-
80053954075
-
Pharmacogenomics of clopidogrel: Evidence and perspectives
-
21592545
-
Yin T, Miyata T. Pharmacogenomics of clopidogrel: evidence and perspectives. Thromb Res. 2011;128(4):307-16.
-
(2011)
Thromb Res.
, vol.128
, Issue.4
, pp. 307-316
-
-
Yin, T.1
Miyata, T.2
-
24
-
-
38649126903
-
Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms
-
17992535
-
Thieme D, Rolf B, Sachs H, Schmid D. Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms. Int J Legal Med. 2008;122(2):149-55.
-
(2008)
Int J Legal Med.
, vol.122
, Issue.2
, pp. 149-155
-
-
Thieme, D.1
Rolf, B.2
Sachs, H.3
Schmid, D.4
-
25
-
-
84876665512
-
Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants
-
3689226 1:CAS:528:DC%2BC3sXmsVWqsrk%3D 23486447
-
Hicks JK, Swen JJ, Thorn CF, Sangkuhl K, Kharasch ED, Ellingrod VL, et al. Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants. Clin Pharmacol Ther. 2013;93(5):402-8.
-
(2013)
Clin Pharmacol Ther.
, vol.93
, Issue.5
, pp. 402-408
-
-
Hicks, J.K.1
Swen, J.J.2
Thorn, C.F.3
Sangkuhl, K.4
Kharasch, E.D.5
Ellingrod, V.L.6
-
26
-
-
38549096032
-
CYP2D6 genotyping and codeine
-
18230077 (author reply 5-6)
-
de Leon J. CYP2D6 genotyping and codeine. Paediatr Anaesth. 2008;18(3):274-5 (author reply 5-6).
-
(2008)
Paediatr Anaesth.
, vol.18
, Issue.3
, pp. 274-275
-
-
De Leon, J.1
-
27
-
-
84871795709
-
Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms
-
22428763
-
Slanar O, Dupal P, Matouskova O, Vondrackova H, Pafko P, Perlik F. Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms. Bratislavske lekarske listy. 2012;113(3):152-5.
-
(2012)
Bratislavske Lekarske Listy.
, vol.113
, Issue.3
, pp. 152-155
-
-
Slanar, O.1
Dupal, P.2
Matouskova, O.3
Vondrackova, H.4
Pafko, P.5
Perlik, F.6
-
28
-
-
34548650021
-
CYP2D6 polymorphisms and the impact on tamoxifen therapy
-
17518364
-
Beverage JN, Sissung TM, Sion AM, Danesi R, Figg WD. CYP2D6 polymorphisms and the impact on tamoxifen therapy. J Pharm Sci. 2007;96(9):2224-31.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.9
, pp. 2224-2231
-
-
Beverage, J.N.1
Sissung, T.M.2
Sion, A.M.3
Danesi, R.4
Figg, W.D.5
-
29
-
-
81255179649
-
Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms
-
Vinetti M, Haufroid V, Capron A, Classen JF, Marchandise S, Hantson P. Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms. Clin Toxicol. 2011;49(9):865-9.
-
(2011)
Clin Toxicol.
, vol.49
, Issue.9
, pp. 865-869
-
-
Vinetti, M.1
Haufroid, V.2
Capron, A.3
Classen, J.F.4
Marchandise, S.5
Hantson, P.6
-
30
-
-
67349129782
-
Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers
-
19429471
-
Borobia AM, Novalbos J, Guerra-Lopez P, Lopez-Rodriguez R, Tabares B, Rodriguez V, et al. Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers. Pharmacol Res. 2009;59(6):393-8.
-
(2009)
Pharmacol Res.
, vol.59
, Issue.6
, pp. 393-398
-
-
Borobia, A.M.1
Novalbos, J.2
Guerra-Lopez, P.3
Lopez-Rodriguez, R.4
Tabares, B.5
Rodriguez, V.6
-
31
-
-
77952869071
-
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety
-
2935998 1:CAS:528:DC%2BC3cXpsVKntrk%3D 20590588
-
Samer CF, Daali Y, Wagner M, Hopfgartner G, Eap CB, Rebsamen MC, et al. Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety. Br J Pharmacol. 2010;160(4):919-30.
-
(2010)
Br J Pharmacol.
, vol.160
, Issue.4
, pp. 919-930
-
-
Samer, C.F.1
Daali, Y.2
Wagner, M.3
Hopfgartner, G.4
Eap, C.B.5
Rebsamen, M.C.6
-
32
-
-
33744899315
-
The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients
-
16423440
-
Ueda M, Hirokane G, Morita S, Okawa M, Watanabe T, Akiyama K, et al. The impact of CYP2D6 genotypes on the plasma concentration of paroxetine in Japanese psychiatric patients. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30(3):486-91.
-
(2006)
Prog Neuropsychopharmacol Biol Psychiatry.
, vol.30
, Issue.3
, pp. 486-491
-
-
Ueda, M.1
Hirokane, G.2
Morita, S.3
Okawa, M.4
Watanabe, T.5
Akiyama, K.6
-
33
-
-
12944281041
-
Amitriptyline or not, that is the question: Pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
-
15590749
-
Steimer W, Zopf K, von Amelunxen S, Pfeiffer H, Bachofer J, Popp J, et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy. Clin Chem. 2005;51(2):376-85.
-
(2005)
Clin Chem.
, vol.51
, Issue.2
, pp. 376-385
-
-
Steimer, W.1
Zopf, K.2
Von Amelunxen, S.3
Pfeiffer, H.4
Bachofer, J.5
Popp, J.6
-
34
-
-
84884213885
-
Pharmacogenomics of phase II metabolizing enzymes and drug transporters: Clinical implications
-
23044602
-
Yiannakopoulou E. Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications. Pharmacogenomics J. 2013;13(2):105-9.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.2
, pp. 105-109
-
-
Yiannakopoulou, E.1
-
35
-
-
42449139713
-
UGT1A1∗28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma
-
18300238
-
Liu CY, Chen PM, Chiou TJ, Liu JH, Lin JK, Lin TC, et al. UGT1A1∗28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma. Cancer. 2008;112(9):1932-40.
-
(2008)
Cancer.
, vol.112
, Issue.9
, pp. 1932-1940
-
-
Liu, C.Y.1
Chen, P.M.2
Chiou, T.J.3
Liu, J.H.4
Lin, J.K.5
Lin, T.C.6
-
36
-
-
84876541448
-
Gene expression variability in human hepatic drug metabolizing enzymes and transporters
-
3634068 1:CAS:528:DC%2BC3sXntVKrsLs%3D 23637747
-
Yang L, Price ET, Chang CW, Li Y, Huang Y, Guo LW, et al. Gene expression variability in human hepatic drug metabolizing enzymes and transporters. PloS one. 2013;8(4):e60368.
-
(2013)
PloS One.
, vol.8
, Issue.4
, pp. 60368
-
-
Yang, L.1
Price, E.T.2
Chang, C.W.3
Li, Y.4
Huang, Y.5
Guo, L.W.6
-
37
-
-
33144478521
-
ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: Discrimination of critical variants using a gene-wide haplotype tagging approach
-
16434479
-
Ho GT, Soranzo N, Nimmo ER, Tenesa A, Goldstein DB, Satsangi J. ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Hum Mol Genet. 2006;15(5):797-805.
-
(2006)
Hum Mol Genet.
, vol.15
, Issue.5
, pp. 797-805
-
-
Ho, G.T.1
Soranzo, N.2
Nimmo, E.R.3
Tenesa, A.4
Goldstein, D.B.5
Satsangi, J.6
-
38
-
-
84885029873
-
Functional G1199A ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients
-
23720091
-
Mostafa-Hedeab G, Saber-Ayad MM, Latif IA, Elkashab SO, Elshaboney TH, Mostafa MI, et al. Functional G1199A ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients. J Clin Pharmacol. 2013;53(8):827-33.
-
(2013)
J Clin Pharmacol.
, vol.53
, Issue.8
, pp. 827-833
-
-
Mostafa-Hedeab, G.1
Saber-Ayad, M.M.2
Latif, I.A.3
Elkashab, S.O.4
Elshaboney, T.H.5
Mostafa, M.I.6
-
39
-
-
0034771497
-
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
-
11697464
-
Sakaeda T, Nakamura T, Horinouchi M, Kakumoto M, Ohmoto N, Sakai T, et al. MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharm Res. 2001;18(10):1400-4.
-
(2001)
Pharm Res.
, vol.18
, Issue.10
, pp. 1400-1404
-
-
Sakaeda, T.1
Nakamura, T.2
Horinouchi, M.3
Kakumoto, M.4
Ohmoto, N.5
Sakai, T.6
-
40
-
-
0035369825
-
Genetic susceptibility to adverse drug reactions
-
11395158
-
Pirmohamed M, Park BK. Genetic susceptibility to adverse drug reactions. Trends Pharmacol Sci. 2001;22(6):298-305.
-
(2001)
Trends Pharmacol Sci.
, vol.22
, Issue.6
, pp. 298-305
-
-
Pirmohamed, M.1
Park, B.K.2
-
41
-
-
57349176121
-
Pharmacogenomics of statin response
-
19051133
-
Mangravite LM, Wilke RA, Zhang J, Krauss RM. Pharmacogenomics of statin response. Curr Opin Mol Ther. 2008;10(6):555-61.
-
(2008)
Curr Opin Mol Ther.
, vol.10
, Issue.6
, pp. 555-561
-
-
Mangravite, L.M.1
Wilke, R.A.2
Zhang, J.3
Krauss, R.M.4
-
42
-
-
35748961114
-
Identifying genetic risk factors for serious adverse drug reactions: Current progress and challenges
-
2763923 1:CAS:528:DC%2BD2sXht1els7vI 17971785
-
Wilke RA, Lin DW, Roden DM, Watkins PB, Flockhart D, Zineh I, et al. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges. Nat Rev Drug Discov. 2007;6(11):904-16.
-
(2007)
Nat Rev Drug Discov.
, vol.6
, Issue.11
, pp. 904-916
-
-
Wilke, R.A.1
Lin, D.W.2
Roden, D.M.3
Watkins, P.B.4
Flockhart, D.5
Zineh, I.6
-
43
-
-
49949104757
-
SLCO1B1 variants and statin-induced myopathy-a genomewide study
-
Group SC
-
Group SC, Link E, Parish S, Armitage J, Bowman L, Heath S, et al. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N Engl J Med. 2008;359(8):789-99.
-
(2008)
N Engl J Med.
, vol.359
, Issue.8
, pp. 789-799
-
-
Link, E.1
Parish, S.2
Armitage, J.3
Bowman, L.4
Heath, S.5
-
46
-
-
84906824182
-
Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human mu-opioid receptor (OPRM1)
-
24527749
-
Knapman A, Connor M. Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human mu-opioid receptor (OPRM1). Br J Pharmacol. 2015;172(2):349-63.
-
(2015)
Br J Pharmacol.
, vol.172
, Issue.2
, pp. 349-363
-
-
Knapman, A.1
Connor, M.2
-
47
-
-
84893489593
-
μ-opioid receptor gene variant OPRM1 118 A>G: A summary of its molecular and clinical consequences for pain
-
24236490
-
Walter C, Doehring A, Oertel BG, Lotsch J. μ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain. Pharmacogenomics. 2013;14(15):1915-25.
-
(2013)
Pharmacogenomics.
, vol.14
, Issue.15
, pp. 1915-1925
-
-
Walter, C.1
Doehring, A.2
Oertel, B.G.3
Lotsch, J.4
-
48
-
-
65249146144
-
A common human μ-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain
-
19116204
-
Oertel BG, Kettner M, Scholich K, Renne C, Roskam B, Geisslinger G, et al. A common human μ-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain. J Biol Chem. 2009;284(10):6530-5.
-
(2009)
J Biol Chem.
, vol.284
, Issue.10
, pp. 6530-6535
-
-
Oertel, B.G.1
Kettner, M.2
Scholich, K.3
Renne, C.4
Roskam, B.5
Geisslinger, G.6
-
49
-
-
84905696339
-
2-adrenergic receptor (ADRB2) gene polymorphisms and the risk of asthma: A meta-analysis of case-control studies
-
4128804 25111792
-
2-adrenergic receptor (ADRB2) gene polymorphisms and the risk of asthma: a meta-analysis of case-control studies. PloS one. 2014;9(8):e104488.
-
(2014)
PloS One.
, vol.9
, Issue.8
, pp. 104488
-
-
Liang, S.Q.1
Chen, X.L.2
Deng, J.M.3
Wei, X.4
Gong, C.5
Chen, Z.R.6
-
50
-
-
79954475396
-
β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia
-
3221129 22048503
-
Al-Rubaish A. β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia. Ann Saudi Med. 2011;31(6):586-90.
-
(2011)
Ann Saudi Med.
, vol.31
, Issue.6
, pp. 586-590
-
-
Al-Rubaish, A.1
-
51
-
-
84884211861
-
MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: Analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms
-
21931346
-
Owen SA, Lunt M, Bowes J, Hider SL, Bruce IN, Thomson W, et al. MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms. Pharmacogenomics J. 2013;13(2):137-47.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.2
, pp. 137-147
-
-
Owen, S.A.1
Lunt, M.2
Bowes, J.3
Hider, S.L.4
Bruce, I.N.5
Thomson, W.6
-
52
-
-
77958500384
-
Drug-induced arrhythmia
-
20921449
-
Heist EK, Ruskin JN. Drug-induced arrhythmia. Circulation. 2010;122(14):1426-35.
-
(2010)
Circulation.
, vol.122
, Issue.14
, pp. 1426-1435
-
-
Heist, E.K.1
Ruskin, J.N.2
-
53
-
-
5444264579
-
Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients
-
14760488
-
Paulussen AD, Gilissen RA, Armstrong M, Doevendans PA, Verhasselt P, Smeets HJ, et al. Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients. J Mol Med. 2004;82(3):182-8.
-
(2004)
J Mol Med.
, vol.82
, Issue.3
, pp. 182-188
-
-
Paulussen, A.D.1
Gilissen, R.A.2
Armstrong, M.3
Doevendans, P.A.4
Verhasselt, P.5
Smeets, H.J.6
-
54
-
-
33644874052
-
New mechanism contributing to drug-induced arrhythmia: Rescue of a misprocessed LQT3 mutant
-
16301357
-
Liu K, Yang T, Viswanathan PC, Roden DM. New mechanism contributing to drug-induced arrhythmia: rescue of a misprocessed LQT3 mutant. Circulation. 2005;112(21):3239-46.
-
(2005)
Circulation.
, vol.112
, Issue.21
, pp. 3239-3246
-
-
Liu, K.1
Yang, T.2
Viswanathan, P.C.3
Roden, D.M.4
-
55
-
-
84872259284
-
Drug-induced arrhythmia: Pharmacogenomic prescribing?
-
3538275 23091201
-
Behr ER, Roden D. Drug-induced arrhythmia: pharmacogenomic prescribing? Eur Heart J. 2013;34(2):89-95.
-
(2013)
Eur Heart J.
, vol.34
, Issue.2
, pp. 89-95
-
-
Behr, E.R.1
Roden, D.2
-
56
-
-
84881170186
-
Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes
-
3422407 1:CAS:528:DC%2BC38XmvFChs7g%3D 22584458
-
Ramirez AH, Shaffer CM, Delaney JT, Sexton DP, Levy SE, Rieder MJ, et al. Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes. Pharmacogenomics J. 2013;13(4):325-9.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.4
, pp. 325-329
-
-
Ramirez, A.H.1
Shaffer, C.M.2
Delaney, J.T.3
Sexton, D.P.4
Levy, S.E.5
Rieder, M.J.6
-
57
-
-
0037161355
-
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
-
11997281
-
Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, et al. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation. 2002;105(16):1943-8.
-
(2002)
Circulation.
, vol.105
, Issue.16
, pp. 1943-1948
-
-
Yang, P.1
Kanki, H.2
Drolet, B.3
Yang, T.4
Wei, J.5
Viswanathan, P.C.6
-
58
-
-
0003425462
-
A common polymorphism associated with antibiotic-induced cardiac arrhythmia
-
27073 1:CAS:528:DC%2BD3cXms1CrtLw%3D 10984545
-
Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ, et al. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Proc Natl Acad Sci. 2000;97(19):10613-8.
-
(2000)
Proc Natl Acad Sci
, vol.97
, Issue.19
, pp. 10613-10618
-
-
Sesti, F.1
Abbott, G.W.2
Wei, J.3
Murray, K.T.4
Saksena, S.5
Schwartz, P.J.6
-
59
-
-
0032904146
-
Torsade de pointes induced by cisapride/clarithromycin interaction
-
9972380
-
Piquette RK. Torsade de pointes induced by cisapride/clarithromycin interaction. Ann Pharmacother. 1999;33(1):22-6.
-
(1999)
Ann Pharmacother.
, vol.33
, Issue.1
, pp. 22-26
-
-
Piquette, R.K.1
-
60
-
-
19244371485
-
KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome
-
9386136
-
Donger C, Denjoy I, Berthet M, Neyroud N, Cruaud C, Bennaceur M, et al. KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome. Circulation. 1997;96(9):2778-81.
-
(1997)
Circulation.
, vol.96
, Issue.9
, pp. 2778-2781
-
-
Donger, C.1
Denjoy, I.2
Berthet, M.3
Neyroud, N.4
Cruaud, C.5
Bennaceur, M.6
-
61
-
-
77949756362
-
Genome-wide association studies in pharmacogenomics
-
20300088
-
Daly AK. Genome-wide association studies in pharmacogenomics. Nat Rev Genet. 2010;11(4):241-6.
-
(2010)
Nat Rev Genet.
, vol.11
, Issue.4
, pp. 241-246
-
-
Daly, A.K.1
-
62
-
-
84855906545
-
Using genome-wide association studies to identify genes important in serious adverse drug reactions
-
Daly AK. Using genome-wide association studies to identify genes important in serious adverse drug reactions. Ann Rev Pharmacol Toxicol. 2012;10(52):21-35.
-
(2012)
Ann Rev Pharmacol Toxicol.
, vol.10
, Issue.52
, pp. 21-35
-
-
Daly, A.K.1
-
63
-
-
84901021796
-
Genome-wide association study: A useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics
-
24831277
-
Low SK, Takahashi A, Mushiroda T, Kubo M. Genome-wide association study: a useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics. Clin Cancer Res. 2014;20(10):2541-52.
-
(2014)
Clin Cancer Res.
, vol.20
, Issue.10
, pp. 2541-2552
-
-
Low, S.K.1
Takahashi, A.2
Mushiroda, T.3
Kubo, M.4
-
64
-
-
84871302357
-
Cancer pharmacogenomics: Strategies and challenges
-
3668552 1:CAS:528:DC%2BC38XhslahtLnK 23183705
-
Wheeler HE, Maitland ML, Dolan ME, Cox NJ, Ratain MJ. Cancer pharmacogenomics: strategies and challenges. Nat Rev Genet. 2013;14(1):23-34.
-
(2013)
Nat Rev Genet.
, vol.14
, Issue.1
, pp. 23-34
-
-
Wheeler, H.E.1
Maitland, M.L.2
Dolan, M.E.3
Cox, N.J.4
Ratain, M.J.5
-
65
-
-
79953197983
-
HLA-A∗31:01 and carbamazepine-induced hypersensitivity reactions in Europeans
-
3113609 1:CAS:528:DC%2BC3MXktVyhurs%3D 21428769
-
McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperaviciute D, Carrington M, et al. HLA-A∗31:01 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med. 2011;364(12):1134-43.
-
(2011)
N Engl J Med.
, vol.364
, Issue.12
, pp. 1134-1143
-
-
McCormack, M.1
Alfirevic, A.2
Bourgeois, S.3
Farrell, J.J.4
Kasperaviciute, D.5
Carrington, M.6
-
66
-
-
70349739250
-
The SLCO1B1∗5 genetic variant is associated with statin-induced side effects
-
3417133 1:CAS:528:DC%2BD1MXhsVGnu77E 19833260
-
Voora D, Shah SH, Spasojevic I, Ali S, Reed CR, Salisbury BA, et al. The SLCO1B1∗5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol. 2009;54(17):1609-16.
-
(2009)
J Am Coll Cardiol.
, vol.54
, Issue.17
, pp. 1609-1616
-
-
Voora, D.1
Shah, S.H.2
Spasojevic, I.3
Ali, S.4
Reed, C.R.5
Salisbury, B.A.6
-
67
-
-
67649859295
-
HLA-B∗57:01 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
-
19483685
-
Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, et al. HLA-B∗57:01 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet. 2009;41(7):816-9.
-
(2009)
Nat Genet.
, vol.41
, Issue.7
, pp. 816-819
-
-
Daly, A.K.1
Donaldson, P.T.2
Bhatnagar, P.3
Shen, Y.4
Pe'Er, I.5
Floratos, A.6
-
68
-
-
84859009413
-
Genome-wide association study of serious blistering skin rash caused by drugs
-
21221126
-
Shen Y, Nicoletti P, Floratos A, Pirmohamed M, Molokhia M, Geppetti P, et al. Genome-wide association study of serious blistering skin rash caused by drugs. Pharmacogenomics J. 2012;12(2):96-104.
-
(2012)
Pharmacogenomics J.
, vol.12
, Issue.2
, pp. 96-104
-
-
Shen, Y.1
Nicoletti, P.2
Floratos, A.3
Pirmohamed, M.4
Molokhia, M.5
Geppetti, P.6
-
69
-
-
79951813946
-
Pharmacogenomics of the RNA world: Structural RNA polymorphisms in drug therapy
-
3251919 1:CAS:528:DC%2BC3MXhvFKnsLs%3D 21289622
-
Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, et al. Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy. Clin Pharmacol Ther. 2011;89(3):355-65.
-
(2011)
Clin Pharmacol Ther.
, vol.89
, Issue.3
, pp. 355-365
-
-
Sadee, W.1
Wang, D.2
Papp, A.C.3
Pinsonneault, J.K.4
Smith, R.M.5
Moyer, R.A.6
-
70
-
-
34548764389
-
Genome scan implicates adhesion biological pathways in secondary leukemia
-
17673902
-
Hartford C, Yang W, Cheng C, Fan Y, Liu W, Trevino L, et al. Genome scan implicates adhesion biological pathways in secondary leukemia. Leukemia. 2007;21(10):2128-36.
-
(2007)
Leukemia.
, vol.21
, Issue.10
, pp. 2128-2136
-
-
Hartford, C.1
Yang, W.2
Cheng, C.3
Fan, Y.4
Liu, W.5
Trevino, L.6
-
71
-
-
40549109599
-
Pathway-based association analysis of genome-wide screening data suggest that genes associated with the γ-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia
-
18334916
-
Inada T, Koga M, Ishiguro H, Horiuchi Y, Syu A, Yoshio T, et al. Pathway-based association analysis of genome-wide screening data suggest that genes associated with the γ-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia. Pharmacogenet Genomics. 2008;18(4):317-23.
-
(2008)
Pharmacogenet Genomics.
, vol.18
, Issue.4
, pp. 317-323
-
-
Inada, T.1
Koga, M.2
Ishiguro, H.3
Horiuchi, Y.4
Syu, A.5
Yoshio, T.6
-
72
-
-
44049102035
-
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
-
17505501
-
Kindmark A, Jawaid A, Harbron CG, Barratt BJ, Bengtsson OF, Andersson TB, et al. Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. 2008;8(3):186-95.
-
(2008)
Pharmacogenomics J.
, vol.8
, Issue.3
, pp. 186-195
-
-
Kindmark, A.1
Jawaid, A.2
Harbron, C.G.3
Barratt, B.J.4
Bengtsson, O.F.5
Andersson, T.B.6
-
73
-
-
53449093633
-
Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
-
18594024
-
Sarasquete ME, Garcia-Sanz R, Marin L, Alcoceba M, Chillon MC, Balanzategui A, et al. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood. 2008;112(7):2709-12.
-
(2008)
Blood.
, vol.112
, Issue.7
, pp. 2709-2712
-
-
Sarasquete, M.E.1
Garcia-Sanz, R.2
Marin, L.3
Alcoceba, M.4
Chillon, M.C.5
Balanzategui, A.6
-
74
-
-
70350574270
-
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
-
18521091
-
Volpi S, Heaton C, Mack K, Hamilton JB, Lannan R, Wolfgang CD, et al. Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Mol Psychiatry. 2009;14(11):1024-31.
-
(2009)
Mol Psychiatry.
, vol.14
, Issue.11
, pp. 1024-1031
-
-
Volpi, S.1
Heaton, C.2
Mack, K.3
Hamilton, J.B.4
Lannan, R.5
Wolfgang, C.D.6
-
75
-
-
73349098768
-
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
-
2793040 1:CAS:528:DC%2BC3cXhtVWisLw%3D 19901119
-
Trevino LR, Shimasaki N, Yang W, Panetta JC, Cheng C, Pei D, et al. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol. 2009;27(35):5972-8.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.35
, pp. 5972-5978
-
-
Trevino, L.R.1
Shimasaki, N.2
Yang, W.3
Panetta, J.C.4
Cheng, C.5
Pei, D.6
-
76
-
-
77949773445
-
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
-
20173735
-
Fellay J, Thompson AJ, Ge D, Gumbs CE, Urban TJ, Shianna KV, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature. 2010;464(7287):405-8.
-
(2010)
Nature.
, vol.464
, Issue.7287
, pp. 405-408
-
-
Fellay, J.1
Thompson, A.J.2
Ge, D.3
Gumbs, C.E.4
Urban, T.J.5
Shianna, K.V.6
-
77
-
-
77955082302
-
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
-
20639878
-
Singer JB, Lewitzky S, Leroy E, Yang F, Zhao X, Klickstein L, et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet. 2010;42(8):711-4.
-
(2010)
Nat Genet.
, vol.42
, Issue.8
, pp. 711-714
-
-
Singer, J.B.1
Lewitzky, S.2
Leroy, E.3
Yang, F.4
Zhao, X.5
Klickstein, L.6
-
78
-
-
79551600984
-
Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
-
21149285
-
Ozeki T, Mushiroda T, Yowang A, Takahashi A, Kubo M, Shirakata Y, et al. Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum Mol Genet. 2011;20(5):1034-41.
-
(2011)
Hum Mol Genet.
, vol.20
, Issue.5
, pp. 1034-1041
-
-
Ozeki, T.1
Mushiroda, T.2
Yowang, A.3
Takahashi, A.4
Kubo, M.5
Shirakata, Y.6
-
79
-
-
79957523368
-
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class i and II alleles
-
3129430 1:CAS:528:DC%2BC3MXosVGnsLg%3D 21570397
-
Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, et al. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology. 2011;141(1):338-47.
-
(2011)
Gastroenterology.
, vol.141
, Issue.1
, pp. 338-347
-
-
Lucena, M.I.1
Molokhia, M.2
Shen, Y.3
Urban, T.J.4
Aithal, G.P.5
Andrade, R.J.6
-
80
-
-
84859315750
-
A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes
-
3288202 22100668
-
Kaab S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, et al. A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes. Circ Cardiovasc Genet. 2012;5(1):91-9.
-
(2012)
Circ Cardiovasc Genet.
, vol.5
, Issue.1
, pp. 91-99
-
-
Kaab, S.1
Crawford, D.C.2
Sinner, M.F.3
Behr, E.R.4
Kannankeril, P.J.5
Wilde, A.A.6
-
81
-
-
84868651038
-
Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression
-
22445761
-
Kurose K, Hiratsuka K, Ishiwata K, Nishikawa J, Nonen S, Azuma J, et al. Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression. Psychiatry Res. 2012;198(3):424-9.
-
(2012)
Psychiatry Res.
, vol.198
, Issue.3
, pp. 424-429
-
-
Kurose, K.1
Hiratsuka, K.2
Ishiwata, K.3
Nishikawa, J.4
Nonen, S.5
Azuma, J.6
-
82
-
-
84859101072
-
A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy
-
22293537
-
Kiyotani K, Uno S, Mushiroda T, Takahashi A, Kubo M, Mitsuhata N, et al. A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. Pharmacogenet Genomics. 2012;22(4):229-35.
-
(2012)
Pharmacogenet Genomics.
, vol.22
, Issue.4
, pp. 229-235
-
-
Kiyotani, K.1
Uno, S.2
Mushiroda, T.3
Takahashi, A.4
Kubo, M.5
Mitsuhata, N.6
-
83
-
-
84891275407
-
Genome wide analysis of drug-induced torsades de pointes: Lack of common variants with large effect sizes
-
3819377 1:CAS:528:DC%2BC3sXhslGrurjL 24223155
-
Behr ER, Ritchie MD, Tanaka T, Kaab S, Crawford DC, Nicoletti P, et al. Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. PloS one. 2013;8(11):e78511.
-
(2013)
PloS One.
, vol.8
, Issue.11
, pp. 78511
-
-
Behr, E.R.1
Ritchie, M.D.2
Tanaka, T.3
Kaab, S.4
Crawford, D.C.5
Nicoletti, P.6
-
84
-
-
84872905876
-
A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients
-
21912425
-
Tohkin M, Kaniwa N, Saito Y, Sugiyama E, Kurose K, Nishikawa J, et al. A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. Pharmacogenomics J. 2013;13(1):60-9.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.1
, pp. 60-69
-
-
Tohkin, M.1
Kaniwa, N.2
Saito, Y.3
Sugiyama, E.4
Kurose, K.5
Nishikawa, J.6
-
85
-
-
84862263590
-
HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population
-
22211527
-
Niihara H, Kakamu T, Fujita Y, Kaneko S, Morita E. HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population. J Dermatol. 2012;39(7):594-601.
-
(2012)
J Dermatol.
, vol.39
, Issue.7
, pp. 594-601
-
-
Niihara, H.1
Kakamu, T.2
Fujita, Y.3
Kaneko, S.4
Morita, E.5
-
86
-
-
84883634584
-
A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
-
3978764 24025145
-
Chung S, Low SK, Zembutsu H, Takahashi A, Kubo M, Sasa M, et al. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Breast Cancer Res. 2013;15(5):R81.
-
(2013)
Breast Cancer Res.
, vol.15
, Issue.5
, pp. 81
-
-
Chung, S.1
Low, S.K.2
Zembutsu, H.3
Takahashi, A.4
Kubo, M.5
Sasa, M.6
-
87
-
-
84878247061
-
Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration
-
22310351
-
Fernandez-Rozadilla C, Cazier JB, Moreno V, Crous-Bou M, Guino E, Duran G, et al. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J. 2013;13(3):209-17.
-
(2013)
Pharmacogenomics J.
, vol.13
, Issue.3
, pp. 209-217
-
-
Fernandez-Rozadilla, C.1
Cazier, J.B.2
Moreno, V.3
Crous-Bou, M.4
Guino, E.5
Duran, G.6
-
88
-
-
84883172515
-
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy
-
23776197
-
Leandro-Garcia LJ, Inglada-Perez L, Pita G, Hjerpe E, Leskela S, Jara C, et al. Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy. J Med Genet. 2013;50(9):599-605.
-
(2013)
J Med Genet.
, vol.50
, Issue.9
, pp. 599-605
-
-
Leandro-Garcia, L.J.1
Inglada-Perez, L.2
Pita, G.3
Hjerpe, E.4
Leskela, S.5
Jara, C.6
-
89
-
-
84875979229
-
New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients
-
23570467
-
Zabala W, Cruz R, Barreiro-de Acosta M, Chaparro M, Panes J, Echarri A, et al. New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients. Pharmacogenomics. 2013;14(6):631-40.
-
(2013)
Pharmacogenomics.
, vol.14
, Issue.6
, pp. 631-640
-
-
Zabala, W.1
Cruz, R.2
Barreiro-De Acosta, M.3
Chaparro, M.4
Panes, J.5
Echarri, A.6
-
90
-
-
84873590053
-
Genome-wide study of methotrexate clearance replicates SLCO1B1
-
3567337 1:CAS:528:DC%2BC3sXjtVGiurw%3D 23233662
-
Ramsey LB, Panetta JC, Smith C, Yang W, Fan Y, Winick NJ, et al. Genome-wide study of methotrexate clearance replicates SLCO1B1. Blood. 2013;121(6):898-904.
-
(2013)
Blood.
, vol.121
, Issue.6
, pp. 898-904
-
-
Ramsey, L.B.1
Panetta, J.C.2
Smith, C.3
Yang, W.4
Fan, Y.5
Winick, N.J.6
-
91
-
-
84872549256
-
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy
-
3549006 1:CAS:528:DC%2BC3sXht1Cnsr4%3D 23204130
-
Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, et al. Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy. Clin Cancer Res. 2013;19(2):491-9.
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.2
, pp. 491-499
-
-
Wheeler, H.E.1
Gamazon, E.R.2
Wing, C.3
Njiaju, U.O.4
Njoku, C.5
Baldwin, R.M.6
-
92
-
-
84875632468
-
Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population
-
23180272
-
Park BL, Kim TH, Kim JH, Bae JS, Pasaje CF, Cheong HS, et al. Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population. Hum Genet. 2013;132(3):313-21.
-
(2013)
Hum Genet.
, vol.132
, Issue.3
, pp. 313-321
-
-
Park, B.L.1
Kim, T.H.2
Kim, J.H.3
Bae, J.S.4
Pasaje, C.F.5
Cheong, H.S.6
-
93
-
-
84886265139
-
HLA-B∗13:01 and the dapsone hypersensitivity syndrome
-
24152261
-
Zhang FR, Liu H, Irwanto A, Fu XA, Li Y, Yu GQ, et al. HLA-B∗13:01 and the dapsone hypersensitivity syndrome. N Engl J Med. 2013;369(17):1620-8.
-
(2013)
N Engl J Med.
, vol.369
, Issue.17
, pp. 1620-1628
-
-
Zhang, F.R.1
Liu, H.2
Irwanto, A.3
Fu, X.A.4
Li, Y.5
Yu, G.Q.6
-
94
-
-
84893493861
-
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations
-
24236485
-
Cornejo-Garcia JA, Liou LB, Blanca-Lopez N, Dona I, Chen CH, Chou YC, et al. Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. Pharmacogenomics. 2013;14(15):1857-69.
-
(2013)
Pharmacogenomics.
, vol.14
, Issue.15
, pp. 1857-1869
-
-
Cornejo-Garcia, J.A.1
Liou, L.B.2
Blanca-Lopez, N.3
Dona, I.4
Chen, C.H.5
Chou, Y.C.6
-
95
-
-
84898548767
-
Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses
-
24595012
-
Wheeler HE, Gonzalez-Neira A, Pita G, de la Torre-Montero JC, Alonso R, Lopez-Fernandez LA, et al. Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses. Pharmacogenet Genomics. 2014;24(5):231-7.
-
(2014)
Pharmacogenet Genomics.
, vol.24
, Issue.5
, pp. 231-237
-
-
Wheeler, H.E.1
Gonzalez-Neira, A.2
Pita, G.3
De La Torre-Montero, J.C.4
Alonso, R.5
Lopez-Fernandez, L.A.6
-
96
-
-
84905901610
-
Genetic variants associated with phenytoin-related severe cutaneous adverse reactions
-
25096692
-
Chung WH, Chang WC, Lee YS, Wu YY, Yang CH, Ho HC, et al. Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. JAMA. 2014;312(5):525-34.
-
(2014)
JAMA.
, vol.312
, Issue.5
, pp. 525-534
-
-
Chung, W.H.1
Chang, W.C.2
Lee, Y.S.3
Wu, Y.Y.4
Yang, C.H.5
Ho, H.C.6
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