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Volumn 75, Issue 6, 2015, Pages 589-631

Clinical association between pharmacogenomics and adverse drug reactions

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE DRUG REACTION; GENETIC POLYMORPHISM; GENETICS; HUMAN; PHARMACOGENETICS;

EID: 84928128889     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-015-0375-0     Document Type: Review
Times cited : (48)

References (96)
  • 1
    • 84872936239 scopus 로고    scopus 로고
    • Pharmacogenomics of adverse drug reactions
    • 3707028 1:CAS:528:DC%2BC3sXis1yktL4%3D 23360680
    • Daly AK. Pharmacogenomics of adverse drug reactions. Genome Med. 2013;5(1):5.
    • (2013) Genome Med. , vol.5 , Issue.1 , pp. 5
    • Daly, A.K.1
  • 2
    • 84880479910 scopus 로고    scopus 로고
    • Mobilizing pharmacogenomic analyses during clinical trials in drug development
    • 23859576
    • Bienfait KL, Shaw PM, Murthy G, Warner AW. Mobilizing pharmacogenomic analyses during clinical trials in drug development. Pharmacogenomics. 2013;14(10):1227-35.
    • (2013) Pharmacogenomics. , vol.14 , Issue.10 , pp. 1227-1235
    • Bienfait, K.L.1    Shaw, P.M.2    Murthy, G.3    Warner, A.W.4
  • 3
    • 3042723720 scopus 로고    scopus 로고
    • Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18,820 patients
    • 443443 15231615
    • Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ. 2004;329(7456):15-9.
    • (2004) BMJ. , vol.329 , Issue.7456 , pp. 15-19
    • Pirmohamed, M.1    James, S.2    Meakin, S.3    Green, C.4    Scott, A.K.5    Walley, T.J.6
  • 4
    • 78751584806 scopus 로고    scopus 로고
    • Incidence of adverse drug events and medication errors in Japan: The JADE study
    • 3019321 20872082
    • Morimoto T, Sakuma M, Matsui K, Kuramoto N, Toshiro J, Murakami J, et al. Incidence of adverse drug events and medication errors in Japan: the JADE study. J Gen Intern Med. 2011;26(2):148-53.
    • (2011) J Gen Intern Med. , vol.26 , Issue.2 , pp. 148-153
    • Morimoto, T.1    Sakuma, M.2    Matsui, K.3    Kuramoto, N.4    Toshiro, J.5    Murakami, J.6
  • 5
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • 9555760
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279(15):1200-5.
    • (1998) JAMA. , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 6
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics-drug disposition, drug targets, and side effects
    • 12571262
    • Evans WE, McLeod HL. Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med. 2003;348(6):538-49.
    • (2003) N Engl J Med. , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 7
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
    • 11710893
    • Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA. 2001;286(18):2270-9.
    • (2001) JAMA. , vol.286 , Issue.18 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 8
    • 0034638766 scopus 로고    scopus 로고
    • Pharmacogenetics and adverse drug reactions
    • 11089838
    • Meyer UA. Pharmacogenetics and adverse drug reactions. Lancet. 2000;356(9242):1667-71.
    • (2000) Lancet. , vol.356 , Issue.9242 , pp. 1667-1671
    • Meyer, U.A.1
  • 9
    • 0000197885 scopus 로고
    • The hemolytic effect of primaquine and related compounds: A review
    • 13618370
    • Beutler E. The hemolytic effect of primaquine and related compounds: a review. Blood. 1959;14(2):103-39.
    • (1959) Blood. , vol.14 , Issue.2 , pp. 103-139
    • Beutler, E.1
  • 11
    • 84865516911 scopus 로고    scopus 로고
    • HLA and pharmacogenetics of drug hypersensitivity
    • 22920398
    • Pavlos R, Mallal S, Phillips E. HLA and pharmacogenetics of drug hypersensitivity. Pharmacogenomics. 2012;13(11):1285-306.
    • (2012) Pharmacogenomics. , vol.13 , Issue.11 , pp. 1285-1306
    • Pavlos, R.1    Mallal, S.2    Phillips, E.3
  • 12
    • 84872899545 scopus 로고    scopus 로고
    • Pharmacogenomics of drug-metabolizing enzymes: A recent update on clinical implications and endogenous effects
    • 23089672
    • Sim SC, Kacevska M, Ingelman-Sundberg M. Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects. Pharmacogenomics J. 2013;13(1):1-11.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.1 , pp. 1-11
    • Sim, S.C.1    Kacevska, M.2    Ingelman-Sundberg, M.3
  • 14
    • 79955492923 scopus 로고    scopus 로고
    • Pharmacogenomics: The genetics of variable drug responses
    • 3093198 21502584
    • Roden DM, Wilke RA, Kroemer HK, Stein CM. Pharmacogenomics: the genetics of variable drug responses. Circulation. 2011;123(15):1661-70.
    • (2011) Circulation. , vol.123 , Issue.15 , pp. 1661-1670
    • Roden, D.M.1    Wilke, R.A.2    Kroemer, H.K.3    Stein, C.M.4
  • 15
    • 0034978572 scopus 로고    scopus 로고
    • The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
    • 11434505
    • van der Weide J, Steijns LS, van Weelden MJ, de Haan K. The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. Pharmacogenetics. 2001;11(4):287-91.
    • (2001) Pharmacogenetics. , vol.11 , Issue.4 , pp. 287-291
    • Van Der Weide, J.1    Steijns, L.S.2    Van Weelden, M.J.3    De Haan, K.4
  • 16
    • 79955754985 scopus 로고    scopus 로고
    • CYP2C9 polymorphism in patients with epilepsy: Genotypic frequency analyzes and phenytoin adverse reactions correlation
    • 21537551
    • Twardowschy CA, Werneck LC, Scola RH, De Paola L, Silvado CE. CYP2C9 polymorphism in patients with epilepsy: genotypic frequency analyzes and phenytoin adverse reactions correlation. Arquivos de neuro-psiquiatria. 2011;69(2A):153-8.
    • (2011) Arquivos de Neuro-psiquiatria. , vol.69 , Issue.2 A , pp. 153-158
    • Twardowschy, C.A.1    Werneck, L.C.2    Scola, R.H.3    De Paola, L.4    Silvado, C.E.5
  • 17
    • 52649159919 scopus 로고    scopus 로고
    • Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy
    • 18756910
    • Samardzija M, Topic E, Stefanovic M, Zibar L, Samardzija G, Balen S, et al. Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy. Coll Antropol. 2008;32(2):557-64.
    • (2008) Coll Antropol. , vol.32 , Issue.2 , pp. 557-564
    • Samardzija, M.1    Topic, E.2    Stefanovic, M.3    Zibar, L.4    Samardzija, G.5    Balen, S.6
  • 18
    • 34249728419 scopus 로고    scopus 로고
    • Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting
    • 17562299
    • Lee SY, Lee ST, Kim JW. Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting. J Biochem Mol Biol. 2007;40(3):448-52.
    • (2007) J Biochem Mol Biol. , vol.40 , Issue.3 , pp. 448-452
    • Lee, S.Y.1    Lee, S.T.2    Kim, J.W.3
  • 19
    • 10744225344 scopus 로고    scopus 로고
    • Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use
    • 1574205 1:CAS:528:DC%2BD2cXhsFOis7w%3D 14707031
    • Martinez C, Blanco G, Ladero JM, Garcia-Martin E, Taxonera C, Gamito FG, et al. Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use. Br J Pharmacol. 2004;141(2):205-8.
    • (2004) Br J Pharmacol. , vol.141 , Issue.2 , pp. 205-208
    • Martinez, C.1    Blanco, G.2    Ladero, J.M.3    Garcia-Martin, E.4    Taxonera, C.5    Gamito, F.G.6
  • 20
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • 2014584 1:CAS:528:DC%2BD3MXnvVans7k%3D 11678778
    • Goldstein JA. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol. 2001;52(4):349-55.
    • (2001) Br J Clin Pharmacol. , vol.52 , Issue.4 , pp. 349-355
    • Goldstein, J.A.1
  • 21
    • 0242543259 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C9 gene
    • 14641553
    • Schwarz UI. Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. Eur J Clin Invest. 2003;33(Suppl 2):23-30.
    • (2003) Eur J Clin Invest. , vol.33 , pp. 23-30
    • Schwarz, U.I.1
  • 22
    • 84870002919 scopus 로고    scopus 로고
    • Current status of clopidogrel pharmacogenomics
    • 23171330
    • Giusti B, Gori AM, Marcucci R, Abbate R. Current status of clopidogrel pharmacogenomics. Pharmacogenomics. 2012;13(15):1671-4.
    • (2012) Pharmacogenomics. , vol.13 , Issue.15 , pp. 1671-1674
    • Giusti, B.1    Gori, A.M.2    Marcucci, R.3    Abbate, R.4
  • 23
    • 80053954075 scopus 로고    scopus 로고
    • Pharmacogenomics of clopidogrel: Evidence and perspectives
    • 21592545
    • Yin T, Miyata T. Pharmacogenomics of clopidogrel: evidence and perspectives. Thromb Res. 2011;128(4):307-16.
    • (2011) Thromb Res. , vol.128 , Issue.4 , pp. 307-316
    • Yin, T.1    Miyata, T.2
  • 24
    • 38649126903 scopus 로고    scopus 로고
    • Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms
    • 17992535
    • Thieme D, Rolf B, Sachs H, Schmid D. Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms. Int J Legal Med. 2008;122(2):149-55.
    • (2008) Int J Legal Med. , vol.122 , Issue.2 , pp. 149-155
    • Thieme, D.1    Rolf, B.2    Sachs, H.3    Schmid, D.4
  • 25
    • 84876665512 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants
    • 3689226 1:CAS:528:DC%2BC3sXmsVWqsrk%3D 23486447
    • Hicks JK, Swen JJ, Thorn CF, Sangkuhl K, Kharasch ED, Ellingrod VL, et al. Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants. Clin Pharmacol Ther. 2013;93(5):402-8.
    • (2013) Clin Pharmacol Ther. , vol.93 , Issue.5 , pp. 402-408
    • Hicks, J.K.1    Swen, J.J.2    Thorn, C.F.3    Sangkuhl, K.4    Kharasch, E.D.5    Ellingrod, V.L.6
  • 26
    • 38549096032 scopus 로고    scopus 로고
    • CYP2D6 genotyping and codeine
    • 18230077 (author reply 5-6)
    • de Leon J. CYP2D6 genotyping and codeine. Paediatr Anaesth. 2008;18(3):274-5 (author reply 5-6).
    • (2008) Paediatr Anaesth. , vol.18 , Issue.3 , pp. 274-275
    • De Leon, J.1
  • 27
    • 84871795709 scopus 로고    scopus 로고
    • Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms
    • 22428763
    • Slanar O, Dupal P, Matouskova O, Vondrackova H, Pafko P, Perlik F. Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms. Bratislavske lekarske listy. 2012;113(3):152-5.
    • (2012) Bratislavske Lekarske Listy. , vol.113 , Issue.3 , pp. 152-155
    • Slanar, O.1    Dupal, P.2    Matouskova, O.3    Vondrackova, H.4    Pafko, P.5    Perlik, F.6
  • 29
    • 81255179649 scopus 로고    scopus 로고
    • Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms
    • Vinetti M, Haufroid V, Capron A, Classen JF, Marchandise S, Hantson P. Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms. Clin Toxicol. 2011;49(9):865-9.
    • (2011) Clin Toxicol. , vol.49 , Issue.9 , pp. 865-869
    • Vinetti, M.1    Haufroid, V.2    Capron, A.3    Classen, J.F.4    Marchandise, S.5    Hantson, P.6
  • 30
    • 67349129782 scopus 로고    scopus 로고
    • Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers
    • 19429471
    • Borobia AM, Novalbos J, Guerra-Lopez P, Lopez-Rodriguez R, Tabares B, Rodriguez V, et al. Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers. Pharmacol Res. 2009;59(6):393-8.
    • (2009) Pharmacol Res. , vol.59 , Issue.6 , pp. 393-398
    • Borobia, A.M.1    Novalbos, J.2    Guerra-Lopez, P.3    Lopez-Rodriguez, R.4    Tabares, B.5    Rodriguez, V.6
  • 31
    • 77952869071 scopus 로고    scopus 로고
    • Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety
    • 2935998 1:CAS:528:DC%2BC3cXpsVKntrk%3D 20590588
    • Samer CF, Daali Y, Wagner M, Hopfgartner G, Eap CB, Rebsamen MC, et al. Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety. Br J Pharmacol. 2010;160(4):919-30.
    • (2010) Br J Pharmacol. , vol.160 , Issue.4 , pp. 919-930
    • Samer, C.F.1    Daali, Y.2    Wagner, M.3    Hopfgartner, G.4    Eap, C.B.5    Rebsamen, M.C.6
  • 33
    • 12944281041 scopus 로고    scopus 로고
    • Amitriptyline or not, that is the question: Pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
    • 15590749
    • Steimer W, Zopf K, von Amelunxen S, Pfeiffer H, Bachofer J, Popp J, et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy. Clin Chem. 2005;51(2):376-85.
    • (2005) Clin Chem. , vol.51 , Issue.2 , pp. 376-385
    • Steimer, W.1    Zopf, K.2    Von Amelunxen, S.3    Pfeiffer, H.4    Bachofer, J.5    Popp, J.6
  • 34
    • 84884213885 scopus 로고    scopus 로고
    • Pharmacogenomics of phase II metabolizing enzymes and drug transporters: Clinical implications
    • 23044602
    • Yiannakopoulou E. Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications. Pharmacogenomics J. 2013;13(2):105-9.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.2 , pp. 105-109
    • Yiannakopoulou, E.1
  • 35
    • 42449139713 scopus 로고    scopus 로고
    • UGT1A1∗28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma
    • 18300238
    • Liu CY, Chen PM, Chiou TJ, Liu JH, Lin JK, Lin TC, et al. UGT1A1∗28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma. Cancer. 2008;112(9):1932-40.
    • (2008) Cancer. , vol.112 , Issue.9 , pp. 1932-1940
    • Liu, C.Y.1    Chen, P.M.2    Chiou, T.J.3    Liu, J.H.4    Lin, J.K.5    Lin, T.C.6
  • 36
    • 84876541448 scopus 로고    scopus 로고
    • Gene expression variability in human hepatic drug metabolizing enzymes and transporters
    • 3634068 1:CAS:528:DC%2BC3sXntVKrsLs%3D 23637747
    • Yang L, Price ET, Chang CW, Li Y, Huang Y, Guo LW, et al. Gene expression variability in human hepatic drug metabolizing enzymes and transporters. PloS one. 2013;8(4):e60368.
    • (2013) PloS One. , vol.8 , Issue.4 , pp. 60368
    • Yang, L.1    Price, E.T.2    Chang, C.W.3    Li, Y.4    Huang, Y.5    Guo, L.W.6
  • 37
    • 33144478521 scopus 로고    scopus 로고
    • ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: Discrimination of critical variants using a gene-wide haplotype tagging approach
    • 16434479
    • Ho GT, Soranzo N, Nimmo ER, Tenesa A, Goldstein DB, Satsangi J. ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Hum Mol Genet. 2006;15(5):797-805.
    • (2006) Hum Mol Genet. , vol.15 , Issue.5 , pp. 797-805
    • Ho, G.T.1    Soranzo, N.2    Nimmo, E.R.3    Tenesa, A.4    Goldstein, D.B.5    Satsangi, J.6
  • 38
    • 84885029873 scopus 로고    scopus 로고
    • Functional G1199A ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients
    • 23720091
    • Mostafa-Hedeab G, Saber-Ayad MM, Latif IA, Elkashab SO, Elshaboney TH, Mostafa MI, et al. Functional G1199A ABCB1 polymorphism may have an effect on cyclosporine blood concentration in renal transplanted patients. J Clin Pharmacol. 2013;53(8):827-33.
    • (2013) J Clin Pharmacol. , vol.53 , Issue.8 , pp. 827-833
    • Mostafa-Hedeab, G.1    Saber-Ayad, M.M.2    Latif, I.A.3    Elkashab, S.O.4    Elshaboney, T.H.5    Mostafa, M.I.6
  • 39
    • 0034771497 scopus 로고    scopus 로고
    • MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
    • 11697464
    • Sakaeda T, Nakamura T, Horinouchi M, Kakumoto M, Ohmoto N, Sakai T, et al. MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharm Res. 2001;18(10):1400-4.
    • (2001) Pharm Res. , vol.18 , Issue.10 , pp. 1400-1404
    • Sakaeda, T.1    Nakamura, T.2    Horinouchi, M.3    Kakumoto, M.4    Ohmoto, N.5    Sakai, T.6
  • 40
    • 0035369825 scopus 로고    scopus 로고
    • Genetic susceptibility to adverse drug reactions
    • 11395158
    • Pirmohamed M, Park BK. Genetic susceptibility to adverse drug reactions. Trends Pharmacol Sci. 2001;22(6):298-305.
    • (2001) Trends Pharmacol Sci. , vol.22 , Issue.6 , pp. 298-305
    • Pirmohamed, M.1    Park, B.K.2
  • 42
    • 35748961114 scopus 로고    scopus 로고
    • Identifying genetic risk factors for serious adverse drug reactions: Current progress and challenges
    • 2763923 1:CAS:528:DC%2BD2sXht1els7vI 17971785
    • Wilke RA, Lin DW, Roden DM, Watkins PB, Flockhart D, Zineh I, et al. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges. Nat Rev Drug Discov. 2007;6(11):904-16.
    • (2007) Nat Rev Drug Discov. , vol.6 , Issue.11 , pp. 904-916
    • Wilke, R.A.1    Lin, D.W.2    Roden, D.M.3    Watkins, P.B.4    Flockhart, D.5    Zineh, I.6
  • 43
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genomewide study
    • Group SC
    • Group SC, Link E, Parish S, Armitage J, Bowman L, Heath S, et al. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N Engl J Med. 2008;359(8):789-99.
    • (2008) N Engl J Med. , vol.359 , Issue.8 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3    Bowman, L.4    Heath, S.5
  • 46
    • 84906824182 scopus 로고    scopus 로고
    • Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human mu-opioid receptor (OPRM1)
    • 24527749
    • Knapman A, Connor M. Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human mu-opioid receptor (OPRM1). Br J Pharmacol. 2015;172(2):349-63.
    • (2015) Br J Pharmacol. , vol.172 , Issue.2 , pp. 349-363
    • Knapman, A.1    Connor, M.2
  • 47
    • 84893489593 scopus 로고    scopus 로고
    • μ-opioid receptor gene variant OPRM1 118 A>G: A summary of its molecular and clinical consequences for pain
    • 24236490
    • Walter C, Doehring A, Oertel BG, Lotsch J. μ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain. Pharmacogenomics. 2013;14(15):1915-25.
    • (2013) Pharmacogenomics. , vol.14 , Issue.15 , pp. 1915-1925
    • Walter, C.1    Doehring, A.2    Oertel, B.G.3    Lotsch, J.4
  • 48
    • 65249146144 scopus 로고    scopus 로고
    • A common human μ-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain
    • 19116204
    • Oertel BG, Kettner M, Scholich K, Renne C, Roskam B, Geisslinger G, et al. A common human μ-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain. J Biol Chem. 2009;284(10):6530-5.
    • (2009) J Biol Chem. , vol.284 , Issue.10 , pp. 6530-6535
    • Oertel, B.G.1    Kettner, M.2    Scholich, K.3    Renne, C.4    Roskam, B.5    Geisslinger, G.6
  • 49
    • 84905696339 scopus 로고    scopus 로고
    • 2-adrenergic receptor (ADRB2) gene polymorphisms and the risk of asthma: A meta-analysis of case-control studies
    • 4128804 25111792
    • 2-adrenergic receptor (ADRB2) gene polymorphisms and the risk of asthma: a meta-analysis of case-control studies. PloS one. 2014;9(8):e104488.
    • (2014) PloS One. , vol.9 , Issue.8 , pp. 104488
    • Liang, S.Q.1    Chen, X.L.2    Deng, J.M.3    Wei, X.4    Gong, C.5    Chen, Z.R.6
  • 50
    • 79954475396 scopus 로고    scopus 로고
    • β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia
    • 3221129 22048503
    • Al-Rubaish A. β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia. Ann Saudi Med. 2011;31(6):586-90.
    • (2011) Ann Saudi Med. , vol.31 , Issue.6 , pp. 586-590
    • Al-Rubaish, A.1
  • 51
    • 84884211861 scopus 로고    scopus 로고
    • MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: Analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms
    • 21931346
    • Owen SA, Lunt M, Bowes J, Hider SL, Bruce IN, Thomson W, et al. MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms. Pharmacogenomics J. 2013;13(2):137-47.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.2 , pp. 137-147
    • Owen, S.A.1    Lunt, M.2    Bowes, J.3    Hider, S.L.4    Bruce, I.N.5    Thomson, W.6
  • 52
    • 77958500384 scopus 로고    scopus 로고
    • Drug-induced arrhythmia
    • 20921449
    • Heist EK, Ruskin JN. Drug-induced arrhythmia. Circulation. 2010;122(14):1426-35.
    • (2010) Circulation. , vol.122 , Issue.14 , pp. 1426-1435
    • Heist, E.K.1    Ruskin, J.N.2
  • 53
    • 5444264579 scopus 로고    scopus 로고
    • Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients
    • 14760488
    • Paulussen AD, Gilissen RA, Armstrong M, Doevendans PA, Verhasselt P, Smeets HJ, et al. Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients. J Mol Med. 2004;82(3):182-8.
    • (2004) J Mol Med. , vol.82 , Issue.3 , pp. 182-188
    • Paulussen, A.D.1    Gilissen, R.A.2    Armstrong, M.3    Doevendans, P.A.4    Verhasselt, P.5    Smeets, H.J.6
  • 54
    • 33644874052 scopus 로고    scopus 로고
    • New mechanism contributing to drug-induced arrhythmia: Rescue of a misprocessed LQT3 mutant
    • 16301357
    • Liu K, Yang T, Viswanathan PC, Roden DM. New mechanism contributing to drug-induced arrhythmia: rescue of a misprocessed LQT3 mutant. Circulation. 2005;112(21):3239-46.
    • (2005) Circulation. , vol.112 , Issue.21 , pp. 3239-3246
    • Liu, K.1    Yang, T.2    Viswanathan, P.C.3    Roden, D.M.4
  • 55
    • 84872259284 scopus 로고    scopus 로고
    • Drug-induced arrhythmia: Pharmacogenomic prescribing?
    • 3538275 23091201
    • Behr ER, Roden D. Drug-induced arrhythmia: pharmacogenomic prescribing? Eur Heart J. 2013;34(2):89-95.
    • (2013) Eur Heart J. , vol.34 , Issue.2 , pp. 89-95
    • Behr, E.R.1    Roden, D.2
  • 56
    • 84881170186 scopus 로고    scopus 로고
    • Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes
    • 3422407 1:CAS:528:DC%2BC38XmvFChs7g%3D 22584458
    • Ramirez AH, Shaffer CM, Delaney JT, Sexton DP, Levy SE, Rieder MJ, et al. Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes. Pharmacogenomics J. 2013;13(4):325-9.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.4 , pp. 325-329
    • Ramirez, A.H.1    Shaffer, C.M.2    Delaney, J.T.3    Sexton, D.P.4    Levy, S.E.5    Rieder, M.J.6
  • 57
    • 0037161355 scopus 로고    scopus 로고
    • Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
    • 11997281
    • Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, et al. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation. 2002;105(16):1943-8.
    • (2002) Circulation. , vol.105 , Issue.16 , pp. 1943-1948
    • Yang, P.1    Kanki, H.2    Drolet, B.3    Yang, T.4    Wei, J.5    Viswanathan, P.C.6
  • 58
    • 0003425462 scopus 로고    scopus 로고
    • A common polymorphism associated with antibiotic-induced cardiac arrhythmia
    • 27073 1:CAS:528:DC%2BD3cXms1CrtLw%3D 10984545
    • Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ, et al. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Proc Natl Acad Sci. 2000;97(19):10613-8.
    • (2000) Proc Natl Acad Sci , vol.97 , Issue.19 , pp. 10613-10618
    • Sesti, F.1    Abbott, G.W.2    Wei, J.3    Murray, K.T.4    Saksena, S.5    Schwartz, P.J.6
  • 59
    • 0032904146 scopus 로고    scopus 로고
    • Torsade de pointes induced by cisapride/clarithromycin interaction
    • 9972380
    • Piquette RK. Torsade de pointes induced by cisapride/clarithromycin interaction. Ann Pharmacother. 1999;33(1):22-6.
    • (1999) Ann Pharmacother. , vol.33 , Issue.1 , pp. 22-26
    • Piquette, R.K.1
  • 60
    • 19244371485 scopus 로고    scopus 로고
    • KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome
    • 9386136
    • Donger C, Denjoy I, Berthet M, Neyroud N, Cruaud C, Bennaceur M, et al. KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome. Circulation. 1997;96(9):2778-81.
    • (1997) Circulation. , vol.96 , Issue.9 , pp. 2778-2781
    • Donger, C.1    Denjoy, I.2    Berthet, M.3    Neyroud, N.4    Cruaud, C.5    Bennaceur, M.6
  • 61
    • 77949756362 scopus 로고    scopus 로고
    • Genome-wide association studies in pharmacogenomics
    • 20300088
    • Daly AK. Genome-wide association studies in pharmacogenomics. Nat Rev Genet. 2010;11(4):241-6.
    • (2010) Nat Rev Genet. , vol.11 , Issue.4 , pp. 241-246
    • Daly, A.K.1
  • 62
    • 84855906545 scopus 로고    scopus 로고
    • Using genome-wide association studies to identify genes important in serious adverse drug reactions
    • Daly AK. Using genome-wide association studies to identify genes important in serious adverse drug reactions. Ann Rev Pharmacol Toxicol. 2012;10(52):21-35.
    • (2012) Ann Rev Pharmacol Toxicol. , vol.10 , Issue.52 , pp. 21-35
    • Daly, A.K.1
  • 63
    • 84901021796 scopus 로고    scopus 로고
    • Genome-wide association study: A useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics
    • 24831277
    • Low SK, Takahashi A, Mushiroda T, Kubo M. Genome-wide association study: a useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics. Clin Cancer Res. 2014;20(10):2541-52.
    • (2014) Clin Cancer Res. , vol.20 , Issue.10 , pp. 2541-2552
    • Low, S.K.1    Takahashi, A.2    Mushiroda, T.3    Kubo, M.4
  • 64
  • 65
    • 79953197983 scopus 로고    scopus 로고
    • HLA-A∗31:01 and carbamazepine-induced hypersensitivity reactions in Europeans
    • 3113609 1:CAS:528:DC%2BC3MXktVyhurs%3D 21428769
    • McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperaviciute D, Carrington M, et al. HLA-A∗31:01 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med. 2011;364(12):1134-43.
    • (2011) N Engl J Med. , vol.364 , Issue.12 , pp. 1134-1143
    • McCormack, M.1    Alfirevic, A.2    Bourgeois, S.3    Farrell, J.J.4    Kasperaviciute, D.5    Carrington, M.6
  • 66
    • 70349739250 scopus 로고    scopus 로고
    • The SLCO1B1∗5 genetic variant is associated with statin-induced side effects
    • 3417133 1:CAS:528:DC%2BD1MXhsVGnu77E 19833260
    • Voora D, Shah SH, Spasojevic I, Ali S, Reed CR, Salisbury BA, et al. The SLCO1B1∗5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol. 2009;54(17):1609-16.
    • (2009) J Am Coll Cardiol. , vol.54 , Issue.17 , pp. 1609-1616
    • Voora, D.1    Shah, S.H.2    Spasojevic, I.3    Ali, S.4    Reed, C.R.5    Salisbury, B.A.6
  • 67
    • 67649859295 scopus 로고    scopus 로고
    • HLA-B∗57:01 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
    • 19483685
    • Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, et al. HLA-B∗57:01 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet. 2009;41(7):816-9.
    • (2009) Nat Genet. , vol.41 , Issue.7 , pp. 816-819
    • Daly, A.K.1    Donaldson, P.T.2    Bhatnagar, P.3    Shen, Y.4    Pe'Er, I.5    Floratos, A.6
  • 69
    • 79951813946 scopus 로고    scopus 로고
    • Pharmacogenomics of the RNA world: Structural RNA polymorphisms in drug therapy
    • 3251919 1:CAS:528:DC%2BC3MXhvFKnsLs%3D 21289622
    • Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, et al. Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy. Clin Pharmacol Ther. 2011;89(3):355-65.
    • (2011) Clin Pharmacol Ther. , vol.89 , Issue.3 , pp. 355-365
    • Sadee, W.1    Wang, D.2    Papp, A.C.3    Pinsonneault, J.K.4    Smith, R.M.5    Moyer, R.A.6
  • 70
    • 34548764389 scopus 로고    scopus 로고
    • Genome scan implicates adhesion biological pathways in secondary leukemia
    • 17673902
    • Hartford C, Yang W, Cheng C, Fan Y, Liu W, Trevino L, et al. Genome scan implicates adhesion biological pathways in secondary leukemia. Leukemia. 2007;21(10):2128-36.
    • (2007) Leukemia. , vol.21 , Issue.10 , pp. 2128-2136
    • Hartford, C.1    Yang, W.2    Cheng, C.3    Fan, Y.4    Liu, W.5    Trevino, L.6
  • 71
    • 40549109599 scopus 로고    scopus 로고
    • Pathway-based association analysis of genome-wide screening data suggest that genes associated with the γ-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia
    • 18334916
    • Inada T, Koga M, Ishiguro H, Horiuchi Y, Syu A, Yoshio T, et al. Pathway-based association analysis of genome-wide screening data suggest that genes associated with the γ-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia. Pharmacogenet Genomics. 2008;18(4):317-23.
    • (2008) Pharmacogenet Genomics. , vol.18 , Issue.4 , pp. 317-323
    • Inada, T.1    Koga, M.2    Ishiguro, H.3    Horiuchi, Y.4    Syu, A.5    Yoshio, T.6
  • 72
    • 44049102035 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
    • 17505501
    • Kindmark A, Jawaid A, Harbron CG, Barratt BJ, Bengtsson OF, Andersson TB, et al. Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. 2008;8(3):186-95.
    • (2008) Pharmacogenomics J. , vol.8 , Issue.3 , pp. 186-195
    • Kindmark, A.1    Jawaid, A.2    Harbron, C.G.3    Barratt, B.J.4    Bengtsson, O.F.5    Andersson, T.B.6
  • 73
    • 53449093633 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
    • 18594024
    • Sarasquete ME, Garcia-Sanz R, Marin L, Alcoceba M, Chillon MC, Balanzategui A, et al. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood. 2008;112(7):2709-12.
    • (2008) Blood. , vol.112 , Issue.7 , pp. 2709-2712
    • Sarasquete, M.E.1    Garcia-Sanz, R.2    Marin, L.3    Alcoceba, M.4    Chillon, M.C.5    Balanzategui, A.6
  • 74
    • 70350574270 scopus 로고    scopus 로고
    • Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
    • 18521091
    • Volpi S, Heaton C, Mack K, Hamilton JB, Lannan R, Wolfgang CD, et al. Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Mol Psychiatry. 2009;14(11):1024-31.
    • (2009) Mol Psychiatry. , vol.14 , Issue.11 , pp. 1024-1031
    • Volpi, S.1    Heaton, C.2    Mack, K.3    Hamilton, J.B.4    Lannan, R.5    Wolfgang, C.D.6
  • 75
    • 73349098768 scopus 로고    scopus 로고
    • Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
    • 2793040 1:CAS:528:DC%2BC3cXhtVWisLw%3D 19901119
    • Trevino LR, Shimasaki N, Yang W, Panetta JC, Cheng C, Pei D, et al. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol. 2009;27(35):5972-8.
    • (2009) J Clin Oncol. , vol.27 , Issue.35 , pp. 5972-5978
    • Trevino, L.R.1    Shimasaki, N.2    Yang, W.3    Panetta, J.C.4    Cheng, C.5    Pei, D.6
  • 76
    • 77949773445 scopus 로고    scopus 로고
    • ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
    • 20173735
    • Fellay J, Thompson AJ, Ge D, Gumbs CE, Urban TJ, Shianna KV, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature. 2010;464(7287):405-8.
    • (2010) Nature. , vol.464 , Issue.7287 , pp. 405-408
    • Fellay, J.1    Thompson, A.J.2    Ge, D.3    Gumbs, C.E.4    Urban, T.J.5    Shianna, K.V.6
  • 77
    • 77955082302 scopus 로고    scopus 로고
    • A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
    • 20639878
    • Singer JB, Lewitzky S, Leroy E, Yang F, Zhao X, Klickstein L, et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet. 2010;42(8):711-4.
    • (2010) Nat Genet. , vol.42 , Issue.8 , pp. 711-714
    • Singer, J.B.1    Lewitzky, S.2    Leroy, E.3    Yang, F.4    Zhao, X.5    Klickstein, L.6
  • 78
    • 79551600984 scopus 로고    scopus 로고
    • Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
    • 21149285
    • Ozeki T, Mushiroda T, Yowang A, Takahashi A, Kubo M, Shirakata Y, et al. Genome-wide association study identifies HLA-A∗3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum Mol Genet. 2011;20(5):1034-41.
    • (2011) Hum Mol Genet. , vol.20 , Issue.5 , pp. 1034-1041
    • Ozeki, T.1    Mushiroda, T.2    Yowang, A.3    Takahashi, A.4    Kubo, M.5    Shirakata, Y.6
  • 79
    • 79957523368 scopus 로고    scopus 로고
    • Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class i and II alleles
    • 3129430 1:CAS:528:DC%2BC3MXosVGnsLg%3D 21570397
    • Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, et al. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology. 2011;141(1):338-47.
    • (2011) Gastroenterology. , vol.141 , Issue.1 , pp. 338-347
    • Lucena, M.I.1    Molokhia, M.2    Shen, Y.3    Urban, T.J.4    Aithal, G.P.5    Andrade, R.J.6
  • 80
    • 84859315750 scopus 로고    scopus 로고
    • A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes
    • 3288202 22100668
    • Kaab S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, et al. A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes. Circ Cardiovasc Genet. 2012;5(1):91-9.
    • (2012) Circ Cardiovasc Genet. , vol.5 , Issue.1 , pp. 91-99
    • Kaab, S.1    Crawford, D.C.2    Sinner, M.F.3    Behr, E.R.4    Kannankeril, P.J.5    Wilde, A.A.6
  • 81
    • 84868651038 scopus 로고    scopus 로고
    • Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression
    • 22445761
    • Kurose K, Hiratsuka K, Ishiwata K, Nishikawa J, Nonen S, Azuma J, et al. Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression. Psychiatry Res. 2012;198(3):424-9.
    • (2012) Psychiatry Res. , vol.198 , Issue.3 , pp. 424-429
    • Kurose, K.1    Hiratsuka, K.2    Ishiwata, K.3    Nishikawa, J.4    Nonen, S.5    Azuma, J.6
  • 82
    • 84859101072 scopus 로고    scopus 로고
    • A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy
    • 22293537
    • Kiyotani K, Uno S, Mushiroda T, Takahashi A, Kubo M, Mitsuhata N, et al. A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. Pharmacogenet Genomics. 2012;22(4):229-35.
    • (2012) Pharmacogenet Genomics. , vol.22 , Issue.4 , pp. 229-235
    • Kiyotani, K.1    Uno, S.2    Mushiroda, T.3    Takahashi, A.4    Kubo, M.5    Mitsuhata, N.6
  • 83
    • 84891275407 scopus 로고    scopus 로고
    • Genome wide analysis of drug-induced torsades de pointes: Lack of common variants with large effect sizes
    • 3819377 1:CAS:528:DC%2BC3sXhslGrurjL 24223155
    • Behr ER, Ritchie MD, Tanaka T, Kaab S, Crawford DC, Nicoletti P, et al. Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes. PloS one. 2013;8(11):e78511.
    • (2013) PloS One. , vol.8 , Issue.11 , pp. 78511
    • Behr, E.R.1    Ritchie, M.D.2    Tanaka, T.3    Kaab, S.4    Crawford, D.C.5    Nicoletti, P.6
  • 84
    • 84872905876 scopus 로고    scopus 로고
    • A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients
    • 21912425
    • Tohkin M, Kaniwa N, Saito Y, Sugiyama E, Kurose K, Nishikawa J, et al. A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. Pharmacogenomics J. 2013;13(1):60-9.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.1 , pp. 60-69
    • Tohkin, M.1    Kaniwa, N.2    Saito, Y.3    Sugiyama, E.4    Kurose, K.5    Nishikawa, J.6
  • 85
    • 84862263590 scopus 로고    scopus 로고
    • HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population
    • 22211527
    • Niihara H, Kakamu T, Fujita Y, Kaneko S, Morita E. HLA-A31 strongly associates with carbamazepine-induced adverse drug reactions but not with carbamazepine-induced lymphocyte proliferation in a Japanese population. J Dermatol. 2012;39(7):594-601.
    • (2012) J Dermatol. , vol.39 , Issue.7 , pp. 594-601
    • Niihara, H.1    Kakamu, T.2    Fujita, Y.3    Kaneko, S.4    Morita, E.5
  • 86
    • 84883634584 scopus 로고    scopus 로고
    • A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
    • 3978764 24025145
    • Chung S, Low SK, Zembutsu H, Takahashi A, Kubo M, Sasa M, et al. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Breast Cancer Res. 2013;15(5):R81.
    • (2013) Breast Cancer Res. , vol.15 , Issue.5 , pp. 81
    • Chung, S.1    Low, S.K.2    Zembutsu, H.3    Takahashi, A.4    Kubo, M.5    Sasa, M.6
  • 87
    • 84878247061 scopus 로고    scopus 로고
    • Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration
    • 22310351
    • Fernandez-Rozadilla C, Cazier JB, Moreno V, Crous-Bou M, Guino E, Duran G, et al. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J. 2013;13(3):209-17.
    • (2013) Pharmacogenomics J. , vol.13 , Issue.3 , pp. 209-217
    • Fernandez-Rozadilla, C.1    Cazier, J.B.2    Moreno, V.3    Crous-Bou, M.4    Guino, E.5    Duran, G.6
  • 88
    • 84883172515 scopus 로고    scopus 로고
    • Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy
    • 23776197
    • Leandro-Garcia LJ, Inglada-Perez L, Pita G, Hjerpe E, Leskela S, Jara C, et al. Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy. J Med Genet. 2013;50(9):599-605.
    • (2013) J Med Genet. , vol.50 , Issue.9 , pp. 599-605
    • Leandro-Garcia, L.J.1    Inglada-Perez, L.2    Pita, G.3    Hjerpe, E.4    Leskela, S.5    Jara, C.6
  • 89
    • 84875979229 scopus 로고    scopus 로고
    • New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients
    • 23570467
    • Zabala W, Cruz R, Barreiro-de Acosta M, Chaparro M, Panes J, Echarri A, et al. New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients. Pharmacogenomics. 2013;14(6):631-40.
    • (2013) Pharmacogenomics. , vol.14 , Issue.6 , pp. 631-640
    • Zabala, W.1    Cruz, R.2    Barreiro-De Acosta, M.3    Chaparro, M.4    Panes, J.5    Echarri, A.6
  • 90
    • 84873590053 scopus 로고    scopus 로고
    • Genome-wide study of methotrexate clearance replicates SLCO1B1
    • 3567337 1:CAS:528:DC%2BC3sXjtVGiurw%3D 23233662
    • Ramsey LB, Panetta JC, Smith C, Yang W, Fan Y, Winick NJ, et al. Genome-wide study of methotrexate clearance replicates SLCO1B1. Blood. 2013;121(6):898-904.
    • (2013) Blood. , vol.121 , Issue.6 , pp. 898-904
    • Ramsey, L.B.1    Panetta, J.C.2    Smith, C.3    Yang, W.4    Fan, Y.5    Winick, N.J.6
  • 91
    • 84872549256 scopus 로고    scopus 로고
    • Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy
    • 3549006 1:CAS:528:DC%2BC3sXht1Cnsr4%3D 23204130
    • Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, et al. Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy. Clin Cancer Res. 2013;19(2):491-9.
    • (2013) Clin Cancer Res. , vol.19 , Issue.2 , pp. 491-499
    • Wheeler, H.E.1    Gamazon, E.R.2    Wing, C.3    Njiaju, U.O.4    Njoku, C.5    Baldwin, R.M.6
  • 92
    • 84875632468 scopus 로고    scopus 로고
    • Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population
    • 23180272
    • Park BL, Kim TH, Kim JH, Bae JS, Pasaje CF, Cheong HS, et al. Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population. Hum Genet. 2013;132(3):313-21.
    • (2013) Hum Genet. , vol.132 , Issue.3 , pp. 313-321
    • Park, B.L.1    Kim, T.H.2    Kim, J.H.3    Bae, J.S.4    Pasaje, C.F.5    Cheong, H.S.6
  • 93
    • 84886265139 scopus 로고    scopus 로고
    • HLA-B∗13:01 and the dapsone hypersensitivity syndrome
    • 24152261
    • Zhang FR, Liu H, Irwanto A, Fu XA, Li Y, Yu GQ, et al. HLA-B∗13:01 and the dapsone hypersensitivity syndrome. N Engl J Med. 2013;369(17):1620-8.
    • (2013) N Engl J Med. , vol.369 , Issue.17 , pp. 1620-1628
    • Zhang, F.R.1    Liu, H.2    Irwanto, A.3    Fu, X.A.4    Li, Y.5    Yu, G.Q.6
  • 94
    • 84893493861 scopus 로고    scopus 로고
    • Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations
    • 24236485
    • Cornejo-Garcia JA, Liou LB, Blanca-Lopez N, Dona I, Chen CH, Chou YC, et al. Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. Pharmacogenomics. 2013;14(15):1857-69.
    • (2013) Pharmacogenomics. , vol.14 , Issue.15 , pp. 1857-1869
    • Cornejo-Garcia, J.A.1    Liou, L.B.2    Blanca-Lopez, N.3    Dona, I.4    Chen, C.H.5    Chou, Y.C.6
  • 95
    • 84898548767 scopus 로고    scopus 로고
    • Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses
    • 24595012
    • Wheeler HE, Gonzalez-Neira A, Pita G, de la Torre-Montero JC, Alonso R, Lopez-Fernandez LA, et al. Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses. Pharmacogenet Genomics. 2014;24(5):231-7.
    • (2014) Pharmacogenet Genomics. , vol.24 , Issue.5 , pp. 231-237
    • Wheeler, H.E.1    Gonzalez-Neira, A.2    Pita, G.3    De La Torre-Montero, J.C.4    Alonso, R.5    Lopez-Fernandez, L.A.6
  • 96
    • 84905901610 scopus 로고    scopus 로고
    • Genetic variants associated with phenytoin-related severe cutaneous adverse reactions
    • 25096692
    • Chung WH, Chang WC, Lee YS, Wu YY, Yang CH, Ho HC, et al. Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. JAMA. 2014;312(5):525-34.
    • (2014) JAMA. , vol.312 , Issue.5 , pp. 525-534
    • Chung, W.H.1    Chang, W.C.2    Lee, Y.S.3    Wu, Y.Y.4    Yang, C.H.5    Ho, H.C.6


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