메뉴 건너뛰기




Volumn 121, Issue 6, 2013, Pages 898-904

Genome-wide study of methotrexate clearance replicates SLCO1B1

Author keywords

[No Author keywords available]

Indexed keywords

FOLINIC ACID; METHOTREXATE; ORGANIC ANION TRANSPORTER 2;

EID: 84873590053     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-08-452839     Document Type: Article
Times cited : (171)

References (40)
  • 1
    • 20244362526 scopus 로고    scopus 로고
    • Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: A Pediatric Oncology Group study
    • DOI 10.1038/sj.leu.2403703
    • Whitehead VM, Shuster JJ, Vuchich MJ, et al. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study. Leukemia. 2005;19(4):533-536. (Pubitemid 40521156)
    • (2005) Leukemia , vol.19 , Issue.4 , pp. 533-536
    • Whitehead, V.M.1    Shuster, J.J.2    Vuchich, M.J.3    Mahoney Jr., D.H.4    Lauer, S.J.5    Payment, C.6    Koch, P.A.7    Cooley, L.D.8    Look, A.T.9    Pullen, D.J.10    Camitta, B.11
  • 2
    • 79961016780 scopus 로고    scopus 로고
    • Effectiveness of high-dose methotrexate in T-cell lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma: A randomized study by the Children's Oncology Group (POG 9404)
    • Asselin BL, Devidas M, Wang C, et al. Effectiveness of high-dose methotrexate in T-cell lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma: a randomized study by the Children's Oncology Group (POG 9404). Blood. 2011;118(4):874-883.
    • (2011) Blood , vol.118 , Issue.4 , pp. 874-883
    • Asselin, B.L.1    Devidas, M.2    Wang, C.3
  • 3
    • 0038473997 scopus 로고    scopus 로고
    • CNS-directed therapy for childhood acute lymphoblastic leukemia: Childhood ALL Collaborative Group overview of 43 randomized trials
    • DOI 10.1200/JCO.2003.08.047
    • Clarke M, Gaynon P, Hann I, et al. CNS-directed therapy for childhood acute lymphoblastic leukemia: Childhood ALL Collaborative Group overview of 43 randomized trials. J Clin Oncol. 2003; 21(9):1798-1809. (Pubitemid 46646217)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.9 , pp. 1798-1809
    • Clarke, M.1    Gaynon, P.2    Hann, I.3    Harrison, G.4    Masera, G.5    Peto, R.6    Richards, S.7
  • 4
    • 79960462879 scopus 로고    scopus 로고
    • Escalating intravenous methotrexate improves eventfree survival in children with standard-risk acute lymphoblastic leukemia: A report from the Children's Oncology Group
    • Matloub Y, Bostrom BC, Hunger SP, et al. Escalating intravenous methotrexate improves eventfree survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2011;118(2):243-251.
    • (2011) Blood , vol.118 , Issue.2 , pp. 243-251
    • Matloub, Y.1    Bostrom, B.C.2    Hunger, S.P.3
  • 5
    • 79955582395 scopus 로고    scopus 로고
    • Shortening infusion time for high-dose methotrexate alters antileukemic effects: A randomized prospective clinical trial
    • Mikkelsen TS, Sparreboom A, Cheng C, et al. Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial. J Clin Oncol. 2011;29(13): 1771-1778.
    • (2011) J Clin Oncol , vol.29 , Issue.13 , pp. 1771-1778
    • Mikkelsen, T.S.1    Sparreboom, A.2    Cheng, C.3
  • 6
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: A Children's Oncology Group study
    • Borowitz MJ, Devidas M, Hunger SP, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study. Blood. 2008; 111(12):5477-5485.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3
  • 7
    • 84863162896 scopus 로고    scopus 로고
    • ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia
    • Xu H, Cheng C, Devidas M, et al. ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. J Clin Oncol. 2012;30(7):751-757.
    • (2012) J Clin Oncol , vol.30 , Issue.7 , pp. 751-757
    • Xu, H.1    Cheng, C.2    Devidas, M.3
  • 8
    • 0021337107 scopus 로고
    • Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemia
    • Evans WE, Crom WR, Stewart CF, et al. Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemia. Lancet. 1984;1:359-362. (Pubitemid 14183279)
    • (1984) Lancet , vol.1 , Issue.8373 , pp. 359-362
    • Evans, W.E.1    Crom, W.R.2    Stewart, C.F.3
  • 9
    • 0022591568 scopus 로고
    • Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect
    • Evans WE, Crom WR, Abromowitch M, et al. Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect. N Engl J Med. 1986;314(8):471-477.
    • (1986) N Engl J Med , vol.314 , Issue.8 , pp. 471-477
    • Evans, W.E.1    Crom, W.R.2    Abromowitch, M.3
  • 10
    • 73349098768 scopus 로고    scopus 로고
    • Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects
    • Trevino LR, Shimasaki N, Yang W, et al. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol. 2009;27(35):5972-5978.
    • (2009) J Clin Oncol , vol.27 , Issue.35 , pp. 5972-5978
    • Trevino, L.R.1    Shimasaki, N.2    Yang, W.3
  • 11
    • 84855316334 scopus 로고    scopus 로고
    • Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition
    • Ramsey LB, Bruun GH, Yang W, et al. Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition. Genome Res. 2012;22(1):1-8.
    • (2012) Genome Res , vol.22 , Issue.1 , pp. 1-8
    • Ramsey, L.B.1    Bruun, G.H.2    Yang, W.3
  • 13
    • 0023200576 scopus 로고
    • Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia
    • Garre ML, Relling MV, Kalwinsky D, et al. Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia. J Pediatr. 1987;111:606-612. (Pubitemid 17140545)
    • (1987) Journal of Pediatrics , vol.111 , Issue.4 , pp. 606-612
    • Garre, M.L.1    Relling, M.V.2    Kalwinsky, D.3
  • 15
    • 77954519312 scopus 로고    scopus 로고
    • Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia
    • Buitenkamp TD, Mathot RA, de Haas V, Pieters R, Zwaan CM. Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia. Haematologica. 2010;95(7): 1106-1113.
    • (2010) Haematologica , vol.95 , Issue.7 , pp. 1106-1113
    • Buitenkamp, T.D.1    Mathot, R.A.2    De Haas, V.3    Pieters, R.4    Zwaan, C.M.5
  • 16
    • 78651245722 scopus 로고    scopus 로고
    • Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells
    • Panetta JC, Sparreboom A, Pui CH, Relling MV, Evans WE. Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells. PLoS Comput Biol. 2010;6(12): e1001019.
    • (2010) PLoS Comput Biol , vol.6 , Issue.12
    • Panetta, J.C.1    Sparreboom, A.2    Pui, C.H.3    Relling, M.V.4    Evans, W.E.5
  • 17
    • 79952188025 scopus 로고    scopus 로고
    • Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia
    • Yang JJ, Cheng C, Devidas M, et al. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet. 2011;43(3):237-241.
    • (2011) Nat Genet. , vol.43 , Issue.3 , pp. 237-241
    • Yang, J.J.1    Cheng, C.2    Devidas, M.3
  • 18
    • 37549064336 scopus 로고    scopus 로고
    • Mach 1.0: Rapid haplotype reconstruction and missing genotype inference
    • Li Y, Abecasis GR. Mach 1.0: Rapid haplotype reconstruction and missing genotype inference. Am J Hum Genet. 2006;S79:2290.
    • (2006) Am J Hum Genet , vol.S79 , pp. 2290
    • Li, Y.1    Abecasis, G.R.2
  • 20
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics. 2010;26(17):2190-2191.
    • (2010) Bioinformatics , vol.26 , Issue.17 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 21
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • DOI 10.1093/bioinformatics/bth457
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21(2):263-265. (Pubitemid 40202029)
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 23
    • 79952988266 scopus 로고    scopus 로고
    • Functional characterization of liver enhancers that regulate drug-associated transporters
    • Kim MJ, Skewes-Cox P, Fukushima H, et al. Functional characterization of liver enhancers that regulate drug-associated transporters. Clin Pharmacol Ther. 2011;89(4):571-578.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.4 , pp. 571-578
    • Kim, M.J.1    Skewes-Cox, P.2    Fukushima, H.3
  • 25
    • 84855893409 scopus 로고    scopus 로고
    • Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population
    • Chae YJ, Lee KR, Noh CK, et al. Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population. J Pharm Sci. 2012;101(3):1302-1313.
    • (2012) J Pharm Sci , vol.101 , Issue.3 , pp. 1302-1313
    • Chae, Y.J.1    Lee, K.R.2    Noh, C.K.3
  • 26
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • Link E, Parish S, Armitage J, et al. SLCO1B1 variants and statin-induced myopathy - a genomewide study. N Engl J Med. 2008;359(8): 789-799.
    • (2008) N Engl J Med , vol.359 , Issue.8 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 27
    • 42149127614 scopus 로고    scopus 로고
    • The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: The contribution of transporting activity changes by SLCO1B1*15
    • DOI 10.1097/FPC.0b013e3282fb02a3, PII 0121301120080500000006
    • Deng JW, Song IS, Shin HJ, et al. The effects of SLCO1B1&z.ast;15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1&z.ast;15. Pharmacogenet Genomics. 2008; 18(5):424-433. (Pubitemid 351535943)
    • (2008) Pharmacogenetics and Genomics , vol.18 , Issue.5 , pp. 424-433
    • Deng, J.W.1    Song, I.-S.2    Shin, H.J.3    Yeo, C.-W.4    Cho, D.-Y.5    Shon, J.-H.6    Shin, J.-G.7
  • 29
    • 40949126593 scopus 로고    scopus 로고
    • Global analysis of genetic variation in SLCO1B1
    • DOI 10.2217/14622416.9.1.19
    • Pasanen MK, Neuvonen PJ, Niemi M. Global analysis of genetic variation in SLCO1B1. Pharmacogenomics. 2008;9(1):19-33. (Pubitemid 351560529)
    • (2008) Pharmacogenomics , vol.9 , Issue.1 , pp. 19-33
    • Pasanen, M.K.1    Neuvonen, P.J.2    Niemi, M.3
  • 30
    • 67649838598 scopus 로고    scopus 로고
    • Genomewide association meta-analysis for total serum bilirubin levels
    • Johnson AD, Kavousi M, SmithAV, et al. Genomewide association meta-analysis for total serum bilirubin levels. Hum Mol Genet. 2009;18(14): 2700-2710.
    • (2009) Hum Mol Genet , vol.18 , Issue.14 , pp. 2700-2710
    • Johnson, A.D.1    Kavousi, M.2    Smith, A.V.3
  • 31
    • 66849111193 scopus 로고    scopus 로고
    • Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics
    • Innocenti F, Kroetz DL, Schuetz E, et al. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. J Clin Oncol. 2009;27(16):2604-2614.
    • (2009) J Clin Oncol , vol.27 , Issue.16 , pp. 2604-2614
    • Innocenti, F.1    Kroetz, D.L.2    Schuetz, E.3
  • 32
    • 39149108768 scopus 로고    scopus 로고
    • Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide
    • DOI 10.1177/0091270007311569
    • Kalliokoski A, Neuvonen M, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide. J Clin Pharmacol. 2008;48(3):311-321. (Pubitemid 351257770)
    • (2008) Journal of Clinical Pharmacology , vol.48 , Issue.3 , pp. 311-321
    • Kalliokoski, A.1    Neuvonen, M.2    Neuvonen, P.J.3    Niemi, M.4
  • 33
    • 78249236222 scopus 로고    scopus 로고
    • Flavopiridol pharmacogenetics: Clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition
    • Ni W, Ji J, Dai Z, et al. Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition. PLoS One. 2010;5(11):e13792.
    • (2010) PLoS One , vol.5 , Issue.11
    • Ni, W.1    Ji, J.2    Dai, Z.3
  • 34
    • 33751096467 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid
    • DOI 10.1097/01.fpc.0000230416.82349.90, PII 0121301120061200000004
    • Pasanen MK, Neuvonen M, Neuvonen PJ, Niemi M. SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid. Pharmacogenet Genomics. 2006;16(12):873-879. (Pubitemid 44772805)
    • (2006) Pharmacogenetics and Genomics , vol.16 , Issue.12 , pp. 873-879
    • Pasanen, M.K.1    Neuvonen, M.2    Neuvonen, P.J.3    Niemi, M.4
  • 35
    • 0028365137 scopus 로고
    • Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T, non-B acute lymphocytic leukemia: A Pediatric Oncology Group study
    • Camitta B, Mahoney D, Leventhal B, et al. Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T, non-B acute lymphocytic leukemia: a Pediatric Oncology Group study. J Clin Oncol. 1994;12:1383-1389.
    • (1994) J Clin Oncol. , vol.12 , pp. 1383-1389
    • Camitta, B.1    Mahoney, D.2    Leventhal, B.3
  • 37
    • 84862600938 scopus 로고    scopus 로고
    • The clinical pharmacogenomics implementation consortium: CPIC Guideline for SLCO1B1 and simvastatin-induced myopathy
    • Wilke RA, Ramsey LB, Johnson SG, et al. The clinical pharmacogenomics implementation consortium: CPIC Guideline for SLCO1B1 and simvastatin-induced myopathy. Clin Pharmacol Ther. 2012;92(1):112-117.
    • (2012) Clin Pharmacol Ther , vol.92 , Issue.1 , pp. 112-117
    • Wilke, R.A.1    Ramsey, L.B.2    Johnson, S.G.3
  • 38
    • 79953901458 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide 1B1: A genetically polymorphic transporter of major importance for hepatic drug uptake
    • Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev. 2011;63(1): 157-181.
    • (2011) Pharmacol Rev , vol.63 , Issue.1 , pp. 157-181
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 39
    • 84859346272 scopus 로고    scopus 로고
    • In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions
    • Karlgren M, Ahlin G, Bergstrom CA, Svensson R, Palm J, Artursson P. In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. Pharm Res. 2012; 29(2):411-426.
    • (2012) Pharm Res. , vol.29 , Issue.2 , pp. 411-426
    • Karlgren, M.1    Ahlin, G.2    Bergstrom, C.A.3    Svensson, R.4    Palm, J.5    Artursson, P.6
  • 40
    • 0141615878 scopus 로고    scopus 로고
    • Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels when compared with methotrexate alone
    • DOI 10.1093/rheumatology/keg277
    • Fox RI, Morgan SL, Smith HT, Robbins BA, Choc MG, Baggott JE. Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels compared with methotrexate alone. Rheumatology (Oxford). 2003;42(8):989-994. (Pubitemid 37220969)
    • (2003) Rheumatology , vol.42 , Issue.8 , pp. 989-994
    • Fox, R.I.1    Morgan, S.L.2    Smith, H.T.3    Robbins, B.A.4    Choc, M.G.5    Baggott, J.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.