β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia

Annals of Saudi Medicine

Volumn 31, Issue 6, 2011, Pages 586-590

  Al Rubaish, Abdullah ^a  

^a IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BETA 2 ADRENERGIC RECEPTOR; GLUTAMIC ACID; GLUTAMINE; GLYCINE;

AMINO ACID SUBSTITUTION; ARTICLE; ASTHMA; CHILD; CODON; CONTROLLED STUDY; DOWN REGULATION; ETHNICITY; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SAUDI ARABIA; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; CASE CONTROL STUDY; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; MUTATION; PATHOPHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARGININE; ASTHMA; CASE-CONTROL STUDIES; CHILD; DOWN-REGULATION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GLUTAMINE; HAPLOTYPES; HUMANS; MALE; MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREVALENCE; RECEPTORS, ADRENERGIC, BETA-2; SAUDI ARABIA; SEVERITY OF ILLNESS INDEX;

EID: 79954475396     PISSN: 02564947     EISSN: 09754466     Source Type: Journal    
DOI: 10.4103/0256-4947.87094     Document Type: Article

References (20)

1. Fuhlbrigge AL, Adams RJ, Guilbert TW, Grant E, Lozano P, Janson SL, et al. The burden of asthma in the United States level and distribution are dependent on interpretation of the national asthma education and prevention program guidelines. Am J Respir Crit Care Med 2002;166:1044-9. (Pubitemid 35189611)
2. Deen JL, Vos T, Huttly SR, Tulloch J. Injuries and non-communicable diseases: Emerging health problems of children in developing countries. Bull World Health Organ 1999;77:518-24. (Pubitemid 29309661)
3. Hall IP. The future of asthma. Br Med J 1997;314:45-9. (Pubitemid 27023239)
4. Hogg JC. The pathology of asthma. APMIS 1997;105:735-45. (Pubitemid 27450505)
5. Bai TR. Beta2-adrenergic receptors in asthma: A current perspective. Lung 1992;170:125-41.
6. Suarez EC, Saab PG, Llabre MM, Kuhn CM, Zimmerman E. Ethnicity, gender and age affects an adrenoceptors and physiological responses to emotional stress. Psychophysiology 2004;41:450-60. (Pubitemid 38715400)
7. Green SA, Cole G, Jacinto M, Innis M, Liggett SB. A polymorphism of the human beta 2-adrenegic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. J Biol Chem 1993;268:23116-21. (Pubitemid 23328021)
8. Green SA, Turki J, Innis M, Liggett SB. Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonistpromoted regulatory properties. Biochemistry 1994;33:9414-9. (Pubitemid 24272896)
9. Reihsaus E, Innis M, MacIntyre N, Liggett SB. Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects. Am J Respir Cell Mol Biol 1993;8:334-9.
10. Green SA, Turki J, Bejarna P, Hall IP, Ligget SB. Influence of 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. Am J Respir Cell Mol Biol 1995;13:25-33.
11. Dewar JC, Wilkinson J, Wheatley A, Thomas NS, Doull I, Morton N, et al. The glutamine 27 2 adrenoceptor polymorphism is associated with elevated IgE levels in Asthmatic families. J Allergy Clin Immunol 1997;100:261-5. (Pubitemid 27349870)
12. Dewar JC, Wheatley T, Venn A, Morrison JFJ, Britton J, Hall IP. 2 adrenoceptor polymorphism are in linkage disequilibrium, but are not associated with asthma in adult population. Clin Exp Allergy 1998;28:442-8. (Pubitemid 28215766)
13. Weir TD, Mallek N, Sandford AJ, Bai TR, Awadh N, Fitzgerald JM, et al. Beta 2 adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma. Am J Respir Crit Care Med 1998;158:787-91. (Pubitemid 28449441)
14. Thakkinstian A, McEvoy M, Minelli C, Gibson P, Hancox B, Duffy D, et al. Systematic review and meta-analysis of the association between 2-adrenoceptor polymorphisms and asthma: A HuGE review. Am J Epidemiol 2005;62:201-11. (Pubitemid 41373524)
15. Contopoulos-loannidis DG, Manoli EN, Ioannidis JP. Meta-analysis of the association of betaadrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol 2005;115:963-72. (Pubitemid 40616210)
16. Holloway JW, Dunbar PR, Riley GA, Sawyer GM, Fitzharris PF, Pearce N, et al. Association of 2 adrenergic receptor polymorphisms with severe asthma. Clin Exp Allergy 2002;30:1097-103.
17. Al-Frayh A, Benar AB, Al-Jawadi TQ. Prevalence of asthma among Saudi children. Saudi Med J 1992;13:521-4.
18. Alamoudi OS. Prevalence of respiratory diseases in hospitalized patients in Saudi Arabia: A 5 years study 1996-2000. Ann Thorac Med 2008;1:76-80.
19. Maxwell TJ, Ameyaw MM, Pritchard S. Beta2-adrenergic receptor genotypes and haplotypes in different ethnic groups. Int J Mol Med 2005;16:573-80.
20. Carroll CL, Stoltz P, Schramm CM, Zucker AR. 2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations. Chest 2009;135:1186-92.