-
1
-
-
13144261678
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters β-endorphin binding and activity: Possible implications for opiate addiction
-
DOI 10.1073/pnas.95.16.9608
-
Bond C, LaForge KS, Tian M et al. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc. Natl Acad. Sci. USA 95(16), 9608-9613 (1998). (Pubitemid 28506279)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.16
, pp. 9608-9613
-
-
Bond, C.1
Laforge, K.S.2
Tian, M.3
Melia, D.4
Zhang, S.5
Borg, L.6
Gong, J.7
Schluger, J.8
Strong, J.A.9
Leal, S.M.10
Tischfield, J.A.11
Kreek, M.J.12
Yu, L.13
-
2
-
-
0028952242
-
The human mu opioid receptor: Modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C
-
Mestek A, Hurley JH, Bye LS et al. The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C. J. Neurosci. 15(3 Pt 2), 2396-2406 (1995).
-
(1995)
J. Neurosci
, vol.15
, Issue.3 PART 2
, pp. 2396-2406
-
-
Mestek, A.1
Hurley, J.H.2
Bye, L.S.3
-
3
-
-
2042527666
-
Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor
-
Beyer A, Koch T, Schroder H, Schulz S, Höllt V. Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor. J. Neurochem. 89(3), 553-560 (2004). (Pubitemid 38534141)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.3
, pp. 553-560
-
-
Beyer, A.1
Koch, T.2
Schroder, H.3
Schulz, S.4
Hollt, V.5
-
4
-
-
34548653719
-
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor
-
DOI 10.1111/j.1471-4159.2007.04738.x
-
Kroslak T, Laforge KS, Gianotti RJ, Ho A, Nielsen DA, Kreek MJ. The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. J. Neurochem. 103(1), 77-87 (2007). (Pubitemid 47404205)
-
(2007)
Journal of Neurochemistry
, vol.103
, Issue.1
, pp. 77-87
-
-
Kroslak, T.1
Laforge, K.S.2
Gianotti, R.J.3
Ho, A.4
Nielsen, D.A.5
Kreek, M.J.6
-
5
-
-
65249146144
-
A common human mu-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain
-
Oertel BG, Kettner M, Scholich K et al. A common human mu-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain. J. Biol. Chem. 284(10), 6530-6535 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, Issue.10
, pp. 6530-6535
-
-
Oertel, B.G.1
Kettner, M.2
Scholich, K.3
-
6
-
-
72849146368
-
Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction
-
Deb I, Chakraborty J, Gangopadhyay PK, Choudhury SR, Das S. Single-nucleotide polymorphism (A118G) in exon 1 of OPRM1 gene causes alteration in downstream signaling by mu-opioid receptor and may contribute to the genetic risk for addiction. J. Neurochem. 112(2), 486-496 (2010).
-
(2010)
J. Neurochem
, vol.112
, Issue.2
, pp. 486-496
-
-
Deb, I.1
Chakraborty, J.2
Gangopadhyay, P.K.3
Choudhury, S.R.4
Das, S.5
-
7
-
-
33846926501
-
2+ channels by heterologously expressed wild-type and mutant human μ-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism
-
DOI 10.1152/jn.01007.2006
-
Margas W, Zubkoff I, Schuler HG, Janicki PK, Ruiz-Velasco V. Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism. J. Neurophysiol. 97(2), 1058-1067 (2007). (Pubitemid 46239487)
-
(2007)
Journal of Neurophysiology
, vol.97
, Issue.2
, pp. 1058-1067
-
-
Margas, W.1
Zubkoff, I.2
Schuler, H.G.3
Janicki, P.K.4
Ruiz-Velasco, V.5
-
8
-
-
84864302826
-
A118G Mu opioid receptor polymorphism increases inhibitory effects on CaV2.2 channels
-
Lopez Soto EJ, Raingo J. A118G Mu opioid receptor polymorphism increases inhibitory effects on CaV2.2 channels. Neurosci. Lett. 523(2), 190-194 (2012).
-
(2012)
Neurosci. Lett
, vol.523
, Issue.2
, pp. 190-194
-
-
Lopez Soto, E.J.1
Raingo, J.2
-
9
-
-
25444491710
-
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G
-
DOI 10.1074/jbc.M504942200
-
Zhang Y, Wang D, Johnson AD, Papp AC, Sadee W. Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. J. Biol. Chem. 280(38), 32618-32624 (2005). (Pubitemid 41368304)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.38
, pp. 32618-32624
-
-
Zhang, Y.1
Wang, D.2
Johnson, A.D.3
Papp, A.C.4
Sadee, W.5
-
10
-
-
84867822943
-
Genetic-epigenetic interaction modulates mu-opioid receptor regulation
-
Oertel BG, Doehring A, Roskam B et al. Genetic-epigenetic interaction modulates mu-opioid receptor regulation. Hum. Mol. Genet. 21(21), 4751-4760 (2012).
-
(2012)
Hum. Mol. Genet
, vol.21
, Issue.21
, pp. 4751-4760
-
-
Oertel, B.G.1
Doehring, A.2
Roskam, B.3
-
11
-
-
34548603504
-
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
-
DOI 10.1038/nature06146, PII NATURE06146
-
Jia D, Jurkowska RZ, Zhang X, Jeltsch A, Cheng X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449(7159), 248-251 (2007). (Pubitemid 47402375)
-
(2007)
Nature
, vol.449
, Issue.7159
, pp. 248-251
-
-
Jia, D.1
Jurkowska, R.Z.2
Zhang, X.3
Jeltsch, A.4
Cheng, X.5
-
12
-
-
57149094671
-
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
-
Jurkowska RZ, Anspach N, Urbanke C et al. Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Res. 36(21), 6656-6663 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.21
, pp. 6656-6663
-
-
Jurkowska, R.Z.1
Anspach, N.2
Urbanke, C.3
-
13
-
-
67649817083
-
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior
-
Mague SD, Isiegas C, Huang P, Liu-Chen LY, Lerman C, Blendy JA. Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. Proc. Natl Acad. Sci. USA 106(26), 10847-10852 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.26
, pp. 10847-10852
-
-
Mague, S.D.1
Isiegas, C.2
Huang, P.3
Liu-Chen, L.Y.4
Lerman, C.5
Blendy, J.A.6
-
14
-
-
79960846324
-
A genetic determinant of the striatal dopamine response to alcohol in men
-
Ramchandani VA, Umhau J, Pavon FJ et al. A genetic determinant of the striatal dopamine response to alcohol in men. Mol. Psychiatry 16(8), 809-817 (2011).
-
(2011)
Mol. Psychiatry
, vol.16
, Issue.8
, pp. 809-817
-
-
Ramchandani, V.A.1
Umhau, J.2
Pavon, F.J.3
-
15
-
-
80055014810
-
Pharmacological consequence of the A118G mu opioid receptor polymorphism on morphine-and fentanyl-mediated modulation of Ca(2)(+) channels in humanized mouse sensory neurons
-
Mahmoud S, Thorsell A, Sommer WH et al. Pharmacological consequence of the A118G mu opioid receptor polymorphism on morphine-and fentanyl-mediated modulation of Ca(2)(+) channels in humanized mouse sensory neurons. Anesthesiology 115(5), 1054-1062 (2011).
-
(2011)
Anesthesiology
, vol.115
, Issue.5
, pp. 1054-1062
-
-
Mahmoud, S.1
Thorsell, A.2
Sommer, W.H.3
-
16
-
-
0035793631
-
A single-nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling
-
Befort K, Filliol D, Decaillot FM, Gaveriaux- Ruff C, Hoehe MR, Kieffer BL. A single-nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling. J. Biol. Chem. 276(5), 3130-3137 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, Issue.5
, pp. 3130-3137
-
-
Befort, K.1
Filliol, D.2
Decaillot, F.M.3
Gaveriaux-Ruff, C.4
Hoehe, M.R.5
Kieffer, B.L.6
-
17
-
-
14944361565
-
The A118G single nucleotide polymorphism of the μ-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans
-
DOI 10.1016/j.jpain.2004.11.008
-
Fillingim RB, Kaplan L, Staud R et al. The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J. Pain 6(3), 159-167 (2005). (Pubitemid 40365019)
-
(2005)
Journal of Pain
, vol.6
, Issue.3
, pp. 159-167
-
-
Fillingim, R.B.1
Kaplan, L.2
Staud, R.3
Ness, T.J.4
Glover, T.L.5
Campbell, C.M.6
Mogil, J.S.7
Wallace, M.R.8
-
18
-
-
33846116305
-
The human μ-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation
-
DOI 10.1037/0735-7044.120.6.1218
-
Lötsch J, Stuck B, Hummel T. The human mu-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation. Behav. Neurosci. 120(6), 1218-1224 (2006). (Pubitemid 46058695)
-
(2006)
Behavioral Neuroscience
, vol.120
, Issue.6
, pp. 1218-1224
-
-
Lotsch, J.1
Stuck, B.2
Hummel, T.3
-
19
-
-
73449088010
-
Association of human micro-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients
-
Zhang W, Chang YZ, Kan QC et al. Association of human micro-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients. Anaesthesia 65(2), 130-135 (2010).
-
(2010)
Anaesthesia
, vol.65
, Issue.2
, pp. 130-135
-
-
Zhang, W.1
Chang, Y.Z.2
Kan, Q.C.3
-
20
-
-
40949132164
-
Differential opioid action on sensory and affective cerebral pain processing
-
DOI 10.1038/sj.clpt.6100441, PII 6100441
-
Oertel BG, Preibisch C, Wallenhorst T et al. Differential opioid action on sensory and affective cerebral pain processing. Clin. Pharmacol. Ther. 83(4), 577-588 (2008). (Pubitemid 351417060)
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.4
, pp. 577-588
-
-
Oertel, B.G.1
Preibisch, C.2
Wallenhorst, T.3
Hummel, T.4
Geisslinger, G.5
Lanfermann, H.6
Lotsch, J.7
-
21
-
-
0036792226
-
Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine- 6-glucuronide toxicity?
-
Lötsch J, Zimmermann M, Darimont J et al. Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine- 6-glucuronide toxicity? Anesthesiology 97(4), 814-819 (2002).
-
(2002)
Anesthesiology
, vol.97
, Issue.4
, pp. 814-819
-
-
Lötsch, J.1
Zimmermann, M.2
Darimont, J.3
-
22
-
-
33747126106
-
The μ-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers
-
DOI 10.1097/01.fpc.0000220566.90466.a2, PII 0121301120060900000002
-
Oertel BG, Schmidt R, Schneider A, Geisslinger G, Lötsch J. The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers. Pharmacogenet. Genomics 16(9), 625-636 (2006). (Pubitemid 44223074)
-
(2006)
Pharmacogenetics and Genomics
, vol.16
, Issue.9
, pp. 625-636
-
-
Oertel, B.G.1
Schmidt, R.2
Schneider, A.3
Geisslinger, G.4
Lotsch, J.5
-
23
-
-
14644441712
-
Polymorphism of μ-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response
-
DOI 10.1097/00000542-200503000-00008
-
Romberg RR, Olofsen E, Bijl H et al. Polymorphism of mu-Opioid Receptor Gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response. Anesthesiology 102(3), 522-530 (2005). (Pubitemid 40315140)
-
(2005)
Anesthesiology
, vol.102
, Issue.3
, pp. 522-530
-
-
Romberg, R.R.1
Olofsen, E.2
Bijl, H.3
Taschner, P.E.M.4
Teppema, L.J.5
Sarton, E.Y.6
Van Kleef, J.W.7
Dahan, A.8
-
24
-
-
0344950514
-
Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy
-
DOI 10.1124/dmd.31.5.677
-
Hirota T, Ieiri I, Takane H et al. Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy. Drug Metab. Dispos. 31(5), 677-680 (2003). (Pubitemid 36444178)
-
(2003)
Drug Metabolism and Disposition
, vol.31
, Issue.5
, pp. 677-680
-
-
Hirota, T.1
Ieiri, I.2
Takane, H.3
Sano, H.4
Kawamoto, K.5
Aono, H.6
Yamasaki, A.7
Takeuchi, H.8
Masada, M.9
Shimizu, E.10
Higuchi, S.11
Otsubo, K.12
-
25
-
-
14944377768
-
Variability in alfentanil analgesia maybe attributed to polymorphism in the mu-opiod receptor gene
-
Caraco Y, Maroz Y, Davidson E. Variability in alfentanil analgesia maybe attributed to polymorphism in the mu-opiod receptor gene. Clin. Pharmacol. Ther. 69(2), 63 (2001).
-
(2001)
Clin. Pharmacol. Ther
, vol.69
, Issue.2
, pp. 63
-
-
Caraco, Y.1
Maroz, Y.2
Davidson, E.3
-
26
-
-
51549101026
-
Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women
-
Landau R, Kern C, Columb MO, Smiley RM, Blouin JL. Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women. Pain 139(1), 5-14 (2008).
-
(2008)
Pain
, vol.139
, Issue.1
, pp. 5-14
-
-
Landau, R.1
Kern, C.2
Columb, M.O.3
Smiley, R.M.4
Blouin, J.L.5
-
27
-
-
84855830042
-
Effect of mu-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia
-
Camorcia M, Capogna G, Stirparo S, Berritta C, Blouin JL, Landau R. Effect of mu-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia. Int. J. Obstet. Anesth. 21(1), 40-44 (2012).
-
(2012)
Int. J. Obstet. Anesth
, vol.21
, Issue.1
, pp. 40-44
-
-
Camorcia, M.1
Capogna, G.2
Stirparo, S.3
Berritta, C.4
Blouin, J.L.5
Landau, R.6
-
28
-
-
70350620288
-
Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment
-
Walter C, Lötsch J. Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. Pain 146(3), 270-275 (2009).
-
(2009)
Pain
, vol.146
, Issue.3
, pp. 270-275
-
-
Walter, C.1
Lötsch, J.2
-
29
-
-
8544257029
-
The 118 A > G polymorphism in the human μ-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
-
DOI 10.1111/j.1399-6576.2004.00517.x
-
Klepstad P, Rakvag TT, Kaasa S et al. The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol. Scand. 48(10), 1232-1239 (2004). (Pubitemid 39490855)
-
(2004)
Acta Anaesthesiologica Scandinavica
, vol.48
, Issue.10
, pp. 1232-1239
-
-
Klepstad, P.1
Rakvag, T.T.2
Kaasa, S.3
Holthe, M.4
Dale, O.5
Borchgrevink, P.C.6
Baar, C.7
Vikan, T.8
Krokan, H.E.9
Skorpen, F.10
-
30
-
-
79954583889
-
Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2294 cancer pain patients
-
Klepstad P, Fladvad T, Skorpen F et al. Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients. Pain 152(5), 1139-1145 (2011).
-
(2011)
Pain
, vol.152
, Issue.5
, pp. 1139-1145
-
-
Klepstad, P.1
Fladvad, T.2
Skorpen, F.3
-
31
-
-
84877892328
-
Consequences of the 118A>G polymorphism in the OPRM1 gene: Translation from bench to bedside?
-
Mura E, Govoni S, Racchi M et al. Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside? J. Pain Res. 6, 331-353 (2013).
-
(2013)
J. Pain Res
, vol.6
, pp. 331-353
-
-
Mura, E.1
Govoni, S.2
Racchi, M.3
-
32
-
-
84877926843
-
Functional genomics of pain in analgesic drug development and therapy
-
Lötsch J, Doehring A, Mogil JS, Arndt T, Geisslinger G, Ultsch A. Functional genomics of pain in analgesic drug development and therapy. Pharmacol. Ther. 139(1), 60-70 (2013).
-
(2013)
Pharmacol. Ther
, vol.139
, Issue.1
, pp. 60-70
-
-
Lötsch, J.1
Doehring, A.2
Mogil, J.S.3
Arndt, T.4
Geisslinger, G.5
Ultsch, A.6
-
33
-
-
57749199462
-
The consequence of concomitantly present functional genetic variants for the identification of functional genotype-phenotype associations in pain
-
Lötsch J, Flühr K, Neddermayer T, Doehring A, Geisslinger G. The consequence of concomitantly present functional genetic variants for the identification of functional genotype-phenotype associations in pain. Clin. Pharmacol. Ther. 85(1), 25-30 (2009).
-
(2009)
Clin. Pharmacol. Ther
, vol.85
, Issue.1
, pp. 25-30
-
-
Lötsch, J.1
Flühr, K.2
Neddermayer, T.3
Doehring, A.4
Geisslinger, G.5
-
34
-
-
21844478532
-
Cluster analysis of multiple experimental pain modalities
-
DOI 10.1016/j.pain.2005.04.016, PII S0304395905001855
-
Hastie BA, Riley JL 3rd, Robinson ME et al. Cluster analysis of multiple experimental pain modalities. Pain 116(3), 227-237 (2005). (Pubitemid 40957126)
-
(2005)
Pain
, vol.116
, Issue.3
, pp. 227-237
-
-
Hastie, B.A.1
Riley III, J.L.2
Robinson, M.E.3
Glover, T.4
Campbell, C.M.5
Staud, R.6
Fillingim, R.B.7
-
35
-
-
79953193743
-
Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients
-
Binder A, May D, Baron R et al. Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. PLoS ONE 6(3), e17387 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.3
-
-
Binder, A.1
May, D.2
Baron, R.3
-
36
-
-
77955326429
-
Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment
-
Baron R, Binder A, Wasner G. Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol. 9(8), 807-819 (2010).
-
(2010)
Lancet Neurol
, vol.9
, Issue.8
, pp. 807-819
-
-
Baron, R.1
Binder, A.2
Wasner, G.3
-
37
-
-
84883752835
-
A machine-learned knowledge discovery method for associating complex phenotypes with complex genotypes. Application to pain
-
Lötsch J, Ultsch A. A machine-learned knowledge discovery method for associating complex phenotypes with complex genotypes. Application to pain. J. Biomed. Inform. 46(5), 921-928 (2013).
-
(2013)
J. Biomed. Inform
, vol.46
, Issue.5
, pp. 921-928
-
-
Lötsch, J.1
Ultsch, A.2
-
38
-
-
79959503826
-
The International HapMap Project
-
International HapMap C.
-
International HapMap C. The International HapMap Project. Nature 426(6968), 789-796 (2003).
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 789-796
-
-
-
39
-
-
79952509224
-
Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures
-
Doehring A, Küsener N, Fluhr K, Neddermeyer TJ, Schneider G, Lötsch J. Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures. PLoS ONE 6(3), e17724 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.3
-
-
Doehring, A.1
Küsener, N.2
Fluhr, K.3
Neddermeyer, T.J.4
Schneider, G.5
Lötsch, J.6
-
40
-
-
84885022982
-
Influence of mu-opioid receptor variant on morphine use and self-rated pain following abdominal hysterectomy
-
In Press)
-
Sia AT, Lim Y, Lim EC et al. Influence of mu-opioid receptor variant on morphine use and self-rated pain following abdominal hysterectomy. J. Pain (2013) (In Press).
-
(2013)
J. Pain
-
-
Sia, A.T.1
Lim, Y.2
Lim, E.C.3
-
41
-
-
70449685767
-
Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery
-
Fukuda K, Hayashida M, Ide S et al. Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery. Pain 147(1-3), 194-201 (2009).
-
(2009)
Pain
, vol.147
, Issue.1-3
, pp. 194-201
-
-
Fukuda, K.1
Hayashida, M.2
Ide, S.3
-
42
-
-
33745700802
-
2 Index?
-
DOI 10.1037/1082-989X.11.2.193
-
Huedo-Medina TB, Sanchez-Meca J, Marin- Martinez F, Botella J. Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol. Methods 11(2), 193-206 (2006). (Pubitemid 44001277)
-
(2006)
Psychological Methods
, vol.11
, Issue.2
, pp. 193-206
-
-
Huedo-Medina, T.B.1
Sanchez-Meca, J.2
Marin-Martinez, F.3
Botella, J.4
-
43
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 327(7414), 557-560 (2003). (Pubitemid 37088507)
-
(2003)
British Medical Journal
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.T.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
44
-
-
11944272254
-
A power primer
-
Cohen J. A power primer. Psych. Bull. 112, 155-159 (1992).
-
(1992)
Psych. Bull
, vol.112
, pp. 155-159
-
-
Cohen, J.1
-
45
-
-
0037261291
-
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
-
DOI 10.1067/mcp.2003.5
-
Skarke C, Darimont J, Schmidt H, Geisslinger G, Lötsch J. Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers. Clin. Pharmacol. Ther. 73(1), 107-121 (2003). (Pubitemid 36158492)
-
(2003)
Clinical Pharmacology and Therapeutics
, vol.73
, Issue.1
, pp. 107-121
-
-
Skarke, C.1
Darimont, J.2
Schmidt, H.3
Geisslinger, G.4
Lotsch, J.5
-
46
-
-
0036152705
-
The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine
-
DOI 10.1097/00008571-200201000-00002
-
Lötsch J, Skarke C, Grösch S, Darimont J, Schmidt H, Geisslinger G. The polymorphism A118G of the human mu-opioid receptor gene decreases the clinical activity of morphine-6-glucuronide but not that of morphine. Pharmacogenetics 12(1), 3-9 (2002). (Pubitemid 34112237)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.1
, pp. 3-9
-
-
Lotsch, J.1
Skarke, C.2
Grosch, S.3
Darimont, J.4
Schmidt, H.5
Geisslinger, G.6
-
47
-
-
77954398116
-
The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes
-
Zwisler ST, Enggaard TP, Noehr-Jensen L et al. The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes. Fundam. Clin. Pharmacol. 24(4), 517-524 (2010).
-
(2010)
Fundam. Clin. Pharmacol
, vol.24
, Issue.4
, pp. 517-524
-
-
Zwisler, S.T.1
Enggaard, T.P.2
Noehr-Jensen, L.3
-
48
-
-
30344473318
-
Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action
-
DOI 10.1016/j.clpt.2005.09.010, PII S0009923605004303
-
Lötsch J, Skarke C, Wieting J et al. Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action. Clin. Pharmacol. Ther. 79(1), 72-89 (2006). (Pubitemid 43069580)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.79
, Issue.1
, pp. 72-89
-
-
Lotsch, J.1
Skarke, C.2
Wieting, J.3
Oertel, B.G.4
Schmidt, H.5
Brockmoller, J.6
Geisslinger, G.7
-
49
-
-
0036149110
-
The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade
-
DOI 10.1016/S0893-133X(01)00294-9, PII S0893133X01002949
-
Wand GS, McCaul M, Yang X et al. The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade. Neuropsychopharmacology 26(1), 106-114 (2002). (Pubitemid 34075281)
-
(2002)
Neuropsychopharmacology
, vol.26
, Issue.1
, pp. 106-114
-
-
Wand, G.S.1
McCaul, M.2
Yang, X.3
Reynolds, J.4
Gotjen, D.5
Lee, S.6
Ali, A.7
-
50
-
-
52649103910
-
A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia
-
Sia AT, Lim Y, Lim EC et al. A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia. Anesthesiology 109(3), 520-526 (2008).
-
(2008)
Anesthesiology
, vol.109
, Issue.3
, pp. 520-526
-
-
Sia, A.T.1
Lim, Y.2
Lim, E.C.3
-
51
-
-
33746608902
-
Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
-
DOI 10.1097/00000542-200608000-00016, PII 0000054220060800000016
-
Chou WY, Wang CH, Liu PH, Liu CC, Tseng CC, Jawan B. Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy. Anesthesiology 105(2), 334-337 (2006). (Pubitemid 44148178)
-
(2006)
Anesthesiology
, vol.105
, Issue.2
, pp. 334-337
-
-
Chou, W.-Y.1
Wang, C.-H.2
Liu, P.-H.3
Liu, C.-C.4
Tseng, C.-C.5
Jawan, B.6
-
52
-
-
33745813212
-
Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty
-
Chou WY, Yang LC, Lu HF et al. Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty. Acta Anaesthesiol. Scand. 50(7), 787-792 (2006).
-
(2006)
Acta Anaesthesiol. Scand
, vol.50
, Issue.7
, pp. 787-792
-
-
Chou, W.Y.1
Yang, L.C.2
Lu, H.F.3
-
53
-
-
34249794271
-
Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
-
DOI 10.1016/j.pain.2006.10.023, PII S0304395906005902
-
Reyes-Gibby CC, Shete S, Rakvag T et al. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 130(1-2), 25-30 (2007). (Pubitemid 46850782)
-
(2007)
Pain
, vol.130
, Issue.1-2
, pp. 25-30
-
-
Reyes-Gibby, C.C.1
Shete, S.2
Rakvag, T.3
Bhat, S.V.4
Skorpen, F.5
Bruera, E.6
Kaasa, S.7
Klepstad, P.8
-
54
-
-
40949150784
-
Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief
-
DOI 10.1038/sj.clpt.6100385, PII 6100385
-
Campa D, Gioia A, Tomei A, Poli P, Barale R. Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin. Pharmacol. Ther. 83(4), 559-566 (2008). (Pubitemid 351417058)
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.4
, pp. 559-566
-
-
Campa, D.1
Gioia, A.2
Tomei, A.3
Poli, P.4
Barale, R.5
-
55
-
-
84874630598
-
Polymorphism of mu-Opioid Receptor Gene (OPRM1:c.118A>G) might not protect against or enhance morphine-induced nausea or vomiting
-
Chen LK, Chen SS, Huang CH et al. Polymorphism of mu-Opioid Receptor Gene (OPRM1:c.118A>G) might not protect against or enhance morphine-induced nausea or vomiting. Pain Res. Treat. 2013, 259306 (2013).
-
(2013)
Pain Res. Treat
, vol.2013
, pp. 259306
-
-
Chen, L.K.1
Chen, S.S.2
Huang, C.H.3
-
56
-
-
78650185666
-
Human opioid mu-receptor A118G polymorphism may protect against central pruritus by epidural morphine for post-cesarean analgesia
-
Tsai FF, Fan SZ, Yang YM, Chien KL, Su YN, Chen LK. Human opioid mu-receptor A118G polymorphism may protect against central pruritus by epidural morphine for post-cesarean analgesia. Acta Anaesthesiol. Scand. 54(10), 1265-1269 (2010).
-
(2010)
Acta Anaesthesiol. Scand
, vol.54
, Issue.10
, pp. 1265-1269
-
-
Tsai, F.F.1
Fan, S.Z.2
Yang, Y.M.3
Chien, K.L.4
Su, Y.N.5
Chen, L.K.6
-
57
-
-
84882840256
-
Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain
-
De Gregori M, Garbin G, De Gregori S et al. Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain. Eur. J. Clin. Pharmacol. 69(9), 1651-1658 (2013).
-
(2013)
Eur. J. Clin. Pharmacol
, vol.69
, Issue.9
, pp. 1651-1658
-
-
De Gregori, M.1
Garbin, G.2
De Gregori, S.3
-
58
-
-
70350604669
-
High post surgical opioid requirements in Crohn's disease are not due to a general change in pain sensitivity
-
Huehne K, Leis S, Muenster T et al. High post surgical opioid requirements in Crohn's disease are not due to a general change in pain sensitivity. Eur. J. Pain 13(10), 1036-1042 (2009).
-
(2009)
Eur. J. Pain
, vol.13
, Issue.10
, pp. 1036-1042
-
-
Huehne, K.1
Leis, S.2
Muenster, T.3
-
59
-
-
84878219340
-
The role of hydromorphone and OPRM1 in postoperative pain relief with hydrocodone
-
Boswell MV, Stauble ME, Loyd GE et al. The role of hydromorphone and OPRM1 in postoperative pain relief with hydrocodone. Pain Physician 16(3), E227-E235 (2013).
-
(2013)
Pain Physician
, vol.16
, Issue.3
-
-
Boswell, M.V.1
Stauble, M.E.2
Loyd, G.E.3
-
60
-
-
84856622603
-
Lack of association of OPRM1 and ABCB1 single-nucleotide polymorphisms to oxycodone response in postoperative pain
-
Zwisler ST, Enggaard TP, Mikkelsen S et al. Lack of association of OPRM1 and ABCB1 single-nucleotide polymorphisms to oxycodone response in postoperative pain. J. Clin. Pharmacol. 52(2), 234-242 (2012).
-
(2012)
J. Clin. Pharmacol
, vol.52
, Issue.2
, pp. 234-242
-
-
Zwisler, S.T.1
Enggaard, T.P.2
Mikkelsen, S.3
-
61
-
-
70349678381
-
Polymorphism of the micro-opioid receptor gene (OPRM1 118A>G) affects fentanyl-induced analgesia during anesthesia and recovery
-
Wu WD, Wang Y, Fang YM, Zhou HY. Polymorphism of the micro-opioid receptor gene (OPRM1 118A>G) affects fentanyl-induced analgesia during anesthesia and recovery. Mol. Diagn. Ther. 13(5), 331-337 (2009).
-
(2009)
Mol. Diagn. Ther
, vol.13
, Issue.5
, pp. 331-337
-
-
Wu, W.D.1
Wang, Y.2
Fang, Y.M.3
Zhou, H.Y.4
-
62
-
-
79951495474
-
Study of the OPRM1 A118G genetic polymorphism associated with postoperative nausea and vomiting induced by fentanyl intravenous analgesia
-
Zhang W, Yuan JJ, Kan QC, Zhang LR, Chang YZ, Wang ZY. Study of the OPRM1 A118G genetic polymorphism associated with postoperative nausea and vomiting induced by fentanyl intravenous analgesia. Minerva Anestesiol. 77(1), 33-39 (2011).
-
(2011)
Minerva Anestesiol
, vol.77
, Issue.1
, pp. 33-39
-
-
Zhang, W.1
Yuan, J.J.2
Kan, Q.C.3
Zhang, L.R.4
Chang, Y.Z.5
Wang, Z.Y.6
-
63
-
-
84872865255
-
The effect of OPRM1 and COMT genotypes on the analgesic response to intravenous fentanyl labor analgesia
-
Landau R, Liu SK, Blouin JL, Carvalho B. The effect of OPRM1 and COMT genotypes on the analgesic response to intravenous fentanyl labor analgesia. Anesth. Analg. 116(2), 386-391 (2013).
-
(2013)
Anesth. Analg
, vol.116
, Issue.2
, pp. 386-391
-
-
Landau, R.1
Liu, S.K.2
Blouin, J.L.3
Carvalho, B.4
-
64
-
-
84874589145
-
The correlation between post-operative fentanyl requirements and -opioid receptor gene A118G polymorphism in patients undergoing radical gastrectomy
-
Zhang F, Liao Q, Li L et al. The correlation between post-operative fentanyl requirements and -opioid receptor gene A118G polymorphism in patients undergoing radical gastrectomy. Exp. Ther. Med. 5(4), 1147-1152 (2013).
-
(2013)
Exp. Ther. Med
, vol.5
, Issue.4
, pp. 1147-1152
-
-
Zhang, F.1
Liao, Q.2
Li, L.3
-
65
-
-
84873700767
-
Combined analysis of circulating beta-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects
-
Rhodin A, Gronbladh A, Ginya H et al. Combined analysis of circulating beta-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. Mol. Brain 6, 8 (2013).
-
(2013)
Mol. Brain
, vol.6
, Issue.8
-
-
Rhodin, A.1
Gronbladh, A.2
Ginya, H.3
-
66
-
-
84858001528
-
Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (ultracet) in oxaliplatin-induced painful neuropathy
-
Liu YC, Wang WS. Human mu-opioid receptor gene A118G polymorphism predicts the efficacy of tramadol/acetaminophen combination tablets (ultracet) in oxaliplatin-induced painful neuropathy. Cancer 118(6), 1718-1725 (2012).
-
(2012)
Cancer
, vol.118
, Issue.6
, pp. 1718-1725
-
-
Liu, Y.C.1
Wang, W.S.2
-
67
-
-
84856588142
-
Micro opioid receptor A118G polymorphism and post-operative pain: Opioids' effects on heterozygous patients
-
De Capraris A, Cinnella G, Marolla A et al. Micro opioid receptor A118G polymorphism and post-operative pain: opioids' effects on heterozygous patients. Int. J. Immunopathol. Pharmacol. 24(4), 993-1004 (2011).
-
(2011)
Int. J. Immunopathol. Pharmacol
, vol.24
, Issue.4
, pp. 993-1004
-
-
De Capraris, A.1
Cinnella, G.2
Marolla, A.3
-
68
-
-
70149109673
-
Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers
-
Lötsch J, von Hentig N, Freynhagen R et al. Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers. Pharmacogenet. Genomics 19(6), 429-436 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, Issue.6
, pp. 429-436
-
-
Lötsch, J.1
Von Hentig, N.2
Freynhagen, R.3
-
69
-
-
84871170408
-
The associations between OPRM 1 and COMT genotypes and postoperative pain, opioid use, and opioid-induced sedation
-
Henker RA, Lewis A, Dai F et al. The associations between OPRM 1 and COMT genotypes and postoperative pain, opioid use, and opioid-induced sedation. Biol. Res. Nurs. 15(3), 309-317 (2013).
-
(2013)
Biol. Res. Nurs
, vol.15
, Issue.3
, pp. 309-317
-
-
Henker, R.A.1
Lewis, A.2
Dai, F.3
-
70
-
-
61549091551
-
Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype
-
Hayashida M, Nagashima M, Satoh Y et al. Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype. Pharmacogenomics 9(11), 1605-1616 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, Issue.11
, pp. 1605-1616
-
-
Hayashida, M.1
Nagashima, M.2
Satoh, Y.3
-
71
-
-
8544257029
-
The 118 A > G polymorphism in the human μ-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
-
DOI 10.1111/j.1399-6576.2004.00517.x
-
Klepstad P, Rakvag TT, Kaasa S et al. The 118 A > G polymorphism in the human micro-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol. Scand. 48(10), 1232-1239 (2004). (Pubitemid 39490855)
-
(2004)
Acta Anaesthesiologica Scandinavica
, vol.48
, Issue.10
, pp. 1232-1239
-
-
Klepstad, P.1
Rakvag, T.T.2
Kaasa, S.3
Holthe, M.4
Dale, O.5
Borchgrevink, P.C.6
Baar, C.7
Vikan, T.8
Krokan, H.E.9
Skorpen, F.10
-
72
-
-
34250851677
-
Basic genetic statistics are necessary in studies of functional associations in anesthesiology [1]
-
DOI 10.1097/01.anes.0000268501.61048.18, PII 0000054220070700000028
-
Lötsch J. Basic genetic statistics are necessary in studies of functional associations in anesthesiology. Anesthesiology 107(1), 168-169; author reply 169 (2007). (Pubitemid 46987835)
-
(2007)
Anesthesiology
, vol.107
, Issue.1
, pp. 168-169
-
-
Lotsch, J.1
-
73
-
-
84893515661
-
-
NCBI. dbSNP. www.ncbi.nlm.nih.gov/projects/SNP/snp-ss. cgi?ss=ss28447285
-
DbSNP
-
-
-
74
-
-
84872490207
-
-
The Allele Frequency Database. http://alfred.med.yale.edu/alfred/ SiteTable1A-working.asp?siteuid=SI273135V
-
The Allele Frequency Database
-
-
-
75
-
-
84893455845
-
-
PubMed. www.ncbi.nlm.nih.gov/sites/entrez
-
PubMed
-
-
|