-
1
-
-
42949165089
-
The Role of Aspirin in Cardiovascular Prevention. Implications of Aspirin Resistance
-
DOI 10.1016/j.jacc.2007.11.080, PII S0735109708005706
-
A.Y. Gasparyan, T. Watson, and G.Y. Lip The role of aspirin in cardiovascular prevention: implications of aspirin resistance J Am Coll Cardiol 51 2008 1829 1843 (Pubitemid 351615246)
-
(2008)
Journal of the American College of Cardiology
, vol.51
, Issue.19
, pp. 1829-1843
-
-
Gasparyan, A.Y.1
Watson, T.2
Lip, G.Y.H.3
-
2
-
-
0035899289
-
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
-
DOI 10.1056/NEJMoa010746
-
S. Yusuf, F. Zhao, S.R. Mehta, S. Chrolavicius, G. Tognoni, and K.K. Fox Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation N Engl J Med 345 2001 494 502 (Pubitemid 32758501)
-
(2001)
New England Journal of Medicine
, vol.345
, Issue.7
, pp. 494-502
-
-
Yusuf, S.1
Zhao, F.2
Mehta, S.R.3
Chrolavicius, S.4
Tognoni, G.5
Fox, K.K.6
-
3
-
-
24644495673
-
Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: The PCI-CLARITY study
-
DOI 10.1001/jama.294.10.1224
-
M.S. Sabatine, C.P. Cannon, C.M. Gibson, J.L. Lopez-Sendon, G. Montalescot, P. Theroux, B.S. Lewis, S.A. Murphy, C.H. McCabe, and E. Braunwald Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study Jama 294 2005 1224 1232 (Pubitemid 41352110)
-
(2005)
Journal of the American Medical Association
, vol.294
, Issue.10
, pp. 1224-1232
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
Lopez-Sendon, J.L.4
Montalescot, G.5
Theroux, P.6
Lewis, B.S.7
Murphy, S.A.8
McCabe, C.H.9
Braunwald, E.10
-
4
-
-
20144373281
-
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
-
DOI 10.1056/NEJMoa050522
-
M.S. Sabatine, C.P. Cannon, C.M. Gibson, J.L. Lopez-Sendon, G. Montalescot, P. Theroux, M.J. Claeys, F. Cools, K.A. Hill, A.M. Skene, C.H. McCabe, and E. Braunwald Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation N Engl J Med 352 2005 1179 1189 (Pubitemid 40397259)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.12
, pp. 1179-1189
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
Lopez-Sendon, J.L.4
Montalescot, G.5
Theroux, P.6
Claeys, M.J.7
Cools, F.8
Hill, K.A.9
Skene, A.M.10
McCabe, C.H.11
Braunwald, E.12
-
5
-
-
27644548513
-
Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: Randomised placebo-controlled trial
-
Z.M. Chen, L.X. Jiang, Y.P. Chen, J.X. Xie, H.C. Pan, R. Peto, R. Collins, and L.S. Liu Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial Lancet 366 2005 1607 1621
-
(2005)
Lancet
, vol.366
, pp. 1607-1621
-
-
Chen, Z.M.1
Jiang, L.X.2
Chen, Y.P.3
Xie, J.X.4
Pan, H.C.5
Peto, R.6
Collins, R.7
Liu, L.S.8
-
6
-
-
0037005777
-
Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting
-
DOI 10.1016/S0735-1097(01)01713-2, PII S0735109701017132
-
D.L. Bhatt, M.E. Bertrand, P.B. Berger, P.L. L'Allier, I. Moussa, J.W. Moses, G. Dangas, M. Taniuchi, J.M. Lasala, D.R. Holmes, S.G. Ellis, and E.J. Topol Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting J Am Coll Cardiol 39 2002 9 14 (Pubitemid 34059855)
-
(2002)
Journal of the American College of Cardiology
, vol.39
, Issue.1
, pp. 9-14
-
-
Bhatt, D.L.1
Bertrand, M.E.2
Berger, P.B.3
L'Allier, P.L.4
Moussa, I.5
Moses, J.W.6
Dangas, G.7
Taniuchi, M.8
Lasala, J.M.9
Holmes, D.R.10
Ellis, S.G.11
Topol, E.J.12
-
7
-
-
75949128633
-
Antiplatelet therapies for the treatment of cardiovascular disease
-
A.D. Michelson Antiplatelet therapies for the treatment of cardiovascular disease Nat Rev Drug Discov 9 2010 154 169
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 154-169
-
-
Michelson, A.D.1
-
8
-
-
77955013649
-
Overcoming 'resistance' to antiplatelet therapy: Targeting the issue of nonadherence
-
K. Kolandaivelu, and D.L. Bhatt Overcoming 'resistance' to antiplatelet therapy: targeting the issue of nonadherence Nat Rev Cardiol 7 2010 461 467
-
(2010)
Nat Rev Cardiol
, vol.7
, pp. 461-467
-
-
Kolandaivelu, K.1
Bhatt, D.L.2
-
10
-
-
0038649988
-
Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
-
DOI 10.1161/01.CIR.0000072771.11429.83
-
P.A. Gurbel, K.P. Bliden, B.L. Hiatt, and C.M. O'Connor Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity Circulation 107 2003 2908 2913 (Pubitemid 36736631)
-
(2003)
Circulation
, vol.107
, Issue.23
, pp. 2908-2913
-
-
Gurbel, P.A.1
Bliden, K.P.2
Hiatt, B.L.3
O'Connor, C.M.4
-
12
-
-
34447576539
-
Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis
-
DOI 10.1016/j.ahj.2007.04.014, PII S0002870307003213
-
J.D. Snoep, M.M. Hovens, J.C. Eikenboom, J.G. van der Bom, J.W. Jukema, and M.V. Huisman Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis Am Heart J 154 2007 221 231 (Pubitemid 47069129)
-
(2007)
American Heart Journal
, vol.154
, Issue.2
, pp. 221-231
-
-
Snoep, J.D.1
Hovens, M.M.C.2
Eikenboom, J.C.J.3
Van Der Bom, J.G.4
Jukema, J.W.5
Huisman, M.V.6
-
13
-
-
69249219296
-
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
A.R. Shuldiner, J.R. O'Connell, K.P. Bliden, A. Gandhi, K. Ryan, R.B. Horenstein, C.M. Damcott, R. Pakyz, U.S. Tantry, Q. Gibson, T.I. Pollin, W. Post, A. Parsa, B.D. Mitchell, N. Faraday, W. Herzog, and P.A. Gurbel Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy Jama 302 2009 849 857
-
(2009)
Jama
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
O'Connell, J.R.2
Bliden, K.P.3
Gandhi, A.4
Ryan, K.5
Horenstein, R.B.6
Damcott, C.M.7
Pakyz, R.8
Tantry, U.S.9
Gibson, Q.10
Pollin, T.I.11
Post, W.12
Parsa, A.13
Mitchell, B.D.14
Faraday, N.15
Herzog, W.16
Gurbel, P.A.17
-
14
-
-
10444235983
-
Clopidogrel resistance: A new chapter in a fast-moving story
-
S.D. Wiviott, and E.M. Antman Clopidogrel resistance: a new chapter in a fast-moving story Circulation 109 2004 3064 3067
-
(2004)
Circulation
, vol.109
, pp. 3064-3067
-
-
Wiviott, S.D.1
Antman, E.M.2
-
15
-
-
34447274446
-
Impact of Body Mass Index on Platelet Aggregation After Administration of a High Loading Dose of 600 mg of Clopidogrel Before Percutaneous Coronary Intervention
-
DOI 10.1016/j.amjcard.2007.02.081, PII S0002914907007060
-
D. Sibbing, O. von Beckerath, A. Schomig, A. Kastrati, and N. von Beckerath Impact of body mass index on platelet aggregation after administration of a high loading dose of 600 mg of clopidogrel before percutaneous coronary intervention Am J Cardiol 100 2007 203 205 (Pubitemid 47041981)
-
(2007)
American Journal of Cardiology
, vol.100
, Issue.2
, pp. 203-205
-
-
Sibbing, D.1
Von Beckerath, O.2
Schomig, A.3
Kastrati, A.4
Von Beckerath, N.5
-
16
-
-
70350056868
-
The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy
-
e1-6
-
A. Singla, M.J. Antonino, K.P. Bliden, U.S. Tantry, and P.A. Gurbel The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy Am Heart J 158 2009 784 e1-6
-
(2009)
Am Heart J
, vol.158
, pp. 784
-
-
Singla, A.1
Antonino, M.J.2
Bliden, K.P.3
Tantry, U.S.4
Gurbel, P.A.5
-
17
-
-
36348943475
-
Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
-
DOI 10.1111/j.1538-7836.2007.02775.x
-
J.T. Brandt, S.L. Close, S.J. Iturria, C.D. Payne, N.A. Farid, C.S. Ernest 2nd, D.R. Lachno, D. Salazar, and K.J. Winters Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel J Thromb Haemost 5 2007 2429 2436 (Pubitemid 350154353)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.12
, pp. 2429-2436
-
-
Brandt, J.T.1
Close, S.L.2
Iturria, S.J.3
Payne, C.D.4
Farid, N.A.5
Ernest, C.S.6
Lachno, D.R.7
Salazar, D.8
Winters, K.J.9
-
18
-
-
47649111604
-
The common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjects
-
DOI 10.1111/j.1538-7836.2008.03050.x
-
K. Umemura, T. Furuta, and K. Kondo The common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjects J Thromb Haemost 6 2008 1439 1441 (Pubitemid 352016331)
-
(2008)
Journal of Thrombosis and Haemostasis
, vol.6
, Issue.8
, pp. 1439-1441
-
-
Umemura, K.1
Furuta, T.2
Kondo, K.3
-
19
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, R.D. Hockett, J.T. Brandt, J.R. Walker, E.M. Antman, W. Macias, E. Braunwald, and M.S. Sabatine Cytochrome p-450 polymorphisms and response to clopidogrel N Engl J Med 360 2009 354 362
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
MacIas, W.9
Braunwald, E.10
Sabatine, M.S.11
-
20
-
-
78651239845
-
Paraoxonase-1 is a major determinant of clopidogrel efficacy
-
H.J. Bouman, E. Schomig, J.W. van Werkum, J. Velder, C.M. Hackeng, C. Hirschhauser, C. Waldmann, H.G. Schmalz, J.M. Ten Berg, and D. Taubert Paraoxonase-1 is a major determinant of clopidogrel efficacy Nat Med 17 2011 110 116
-
(2011)
Nat Med
, vol.17
, pp. 110-116
-
-
Bouman, H.J.1
Schomig, E.2
Van Werkum, J.W.3
Velder, J.4
Hackeng, C.M.5
Hirschhauser, C.6
Waldmann, C.7
Schmalz, H.G.8
Ten Berg, J.M.9
Taubert, D.10
-
21
-
-
61349191612
-
Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis
-
B. Giusti, A.M. Gori, R. Marcucci, C. Saracini, I. Sestini, R. Paniccia, P. Buonamici, D. Antoniucci, R. Abbate, and G.F. Gensini Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis Am J Cardiol 103 2009 806 811
-
(2009)
Am J Cardiol
, vol.103
, pp. 806-811
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
Saracini, C.4
Sestini, I.5
Paniccia, R.6
Buonamici, P.7
Antoniucci, D.8
Abbate, R.9
Gensini, G.F.10
-
22
-
-
65249145201
-
Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
-
D. Sibbing, J. Stegherr, W. Latz, W. Koch, J. Mehilli, K. Dorrler, T. Morath, A. Schomig, A. Kastrati, and N. von Beckerath Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention Eur Heart J 30 2009 916 922
-
(2009)
Eur Heart J
, vol.30
, pp. 916-922
-
-
Sibbing, D.1
Stegherr, J.2
Latz, W.3
Koch, W.4
Mehilli, J.5
Dorrler, K.6
Morath, T.7
Schomig, A.8
Kastrati, A.9
Von Beckerath, N.10
-
23
-
-
58749090547
-
Genetic determinants of response to clopidogrel and cardiovascular events
-
T. Simon, C. Verstuyft, M. Mary-Krause, L. Quteineh, E. Drouet, N. Meneveau, P.G. Steg, J. Ferrieres, N. Danchin, and L. Becquemont Genetic determinants of response to clopidogrel and cardiovascular events N Engl J Med 360 2009 363 375
-
(2009)
N Engl J Med
, vol.360
, pp. 363-375
-
-
Simon, T.1
Verstuyft, C.2
Mary-Krause, M.3
Quteineh, L.4
Drouet, E.5
Meneveau, N.6
Steg, P.G.7
Ferrieres, J.8
Danchin, N.9
Becquemont, L.10
-
24
-
-
58249135635
-
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
J.P. Collet, J.S. Hulot, A. Pena, E. Villard, J.B. Esteve, J. Silvain, L. Payot, D. Brugier, G. Cayla, F. Beygui, G. Bensimon, C. Funck-Brentano, and G. Montalescot Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study Lancet 373 2009 309 317
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
Villard, E.4
Esteve, J.B.5
Silvain, J.6
Payot, L.7
Brugier, D.8
Cayla, G.9
Beygui, F.10
Bensimon, G.11
Funck-Brentano, C.12
Montalescot, G.13
-
25
-
-
78049433100
-
Effects of CYP2C19 genotype on outcomes of clopidogrel treatment
-
G. Paré, S.R. Mehta, S. Yusuf, S.S. Anand, S.J. Connolly, J. Hirsh, K. Simonsen, D.L. Bhatt, K.A. Fox, and J.W. Eikelboom Effects of CYP2C19 genotype on outcomes of clopidogrel treatment N Engl J Med 363 2010 1704 1714
-
(2010)
N Engl J Med
, vol.363
, pp. 1704-1714
-
-
Paré, G.1
Mehta, S.R.2
Yusuf, S.3
Anand, S.S.4
Connolly, S.J.5
Hirsh, J.6
Simonsen, K.7
Bhatt, D.L.8
Fox, K.A.9
Eikelboom, J.W.10
-
26
-
-
76349098199
-
Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
-
D. Sibbing, W. Koch, D. Gebhard, T. Schuster, S. Braun, J. Stegherr, T. Morath, A. Schomig, N. von Beckerath, and A. Kastrati Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement Circulation 121 2010 512 518
-
(2010)
Circulation
, vol.121
, pp. 512-518
-
-
Sibbing, D.1
Koch, W.2
Gebhard, D.3
Schuster, T.4
Braun, S.5
Stegherr, J.6
Morath, T.7
Schomig, A.8
Von Beckerath, N.9
Kastrati, A.10
-
27
-
-
37249068049
-
Platelet activation and atherothrombosis
-
G. Davi, and C. Patrono Platelet activation and atherothrombosis N Engl J Med 357 2007 2482 2494
-
(2007)
N Engl J Med
, vol.357
, pp. 2482-2494
-
-
Davi, G.1
Patrono, C.2
-
28
-
-
13044263119
-
A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase
-
C. Trumel, B. Payrastre, M. Plantavid, B. Hechler, C. Viala, P. Presek, E.A. Martinson, J.P. Cazenave, H. Chap, and C. Gachet A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase Blood 94 1999 4156 4165
-
(1999)
Blood
, vol.94
, pp. 4156-4165
-
-
Trumel, C.1
Payrastre, B.2
Plantavid, M.3
Hechler, B.4
Viala, C.5
Presek, P.6
Martinson, E.A.7
Cazenave, J.P.8
Chap, H.9
Gachet, C.10
-
29
-
-
0032873146
-
Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets. Definition and detection of ticlopidine/clopidogrel effects
-
U.R. Schwarz, J. Geiger, U. Walter, and M. Eigenthaler Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets-definition and detection of ticlopidine/clopidogrel effects Thromb Haemost 82 1999 1145 1152 (Pubitemid 29419734)
-
(1999)
Thrombosis and Haemostasis
, vol.82
, Issue.3
, pp. 1145-1152
-
-
Schwarz, U.R.1
Geiger, J.2
Walter, U.3
Eigenthaler, M.4
-
30
-
-
0033678468
-
Identification and biological activity of the active metabolite of clopidogrel
-
P. Savi, J.M. Pereillo, M.F. Uzabiaga, J. Combalbert, C. Picard, J.P. Maffrand, M. Pascal, and J.M. Herbert Identification and biological activity of the active metabolite of clopidogrel Thromb Haemost 84 2000 891 896
-
(2000)
Thromb Haemost
, vol.84
, pp. 891-896
-
-
Savi, P.1
Pereillo, J.M.2
Uzabiaga, M.F.3
Combalbert, J.4
Picard, C.5
Maffrand, J.P.6
Pascal, M.7
Herbert, J.M.8
-
32
-
-
0024451284
-
Platelet inhibitor agents in cardiovascular disease: An update
-
B. Stein, V. Fuster, D.H. Israel, M. Cohen, L. Badimon, J.J. Badimon, and J.H. Chesebro Platelet inhibitor agents in cardiovascular disease: an update J Am Coll Cardiol 14 1989 813 836 (Pubitemid 19250565)
-
(1989)
Journal of the American College of Cardiology
, vol.14
, Issue.4
, pp. 813-836
-
-
Stein, B.1
Fuster, V.2
Israel, D.H.3
Cohen, M.4
Badimon, L.5
Badimon, J.J.6
Chesebro, J.H.7
-
33
-
-
73149119363
-
Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
-
M. Kazui, Y. Nishiya, T. Ishizuka, K. Hagihara, N.A. Farid, O. Okazaki, T. Ikeda, and A. Kurihara Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite Drug Metab Dispos 38 2010 92 99
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 92-99
-
-
Kazui, M.1
Nishiya, Y.2
Ishizuka, T.3
Hagihara, K.4
Farid, N.A.5
Okazaki, O.6
Ikeda, T.7
Kurihara, A.8
-
34
-
-
0032797781
-
Pharmacokinetics of clopidogrel
-
H. Caplain, F. Donat, C. Gaud, and J. Necciari Pharmacokinetics of clopidogrel Semin Thromb Hemost 25 Suppl 2 1999 25 28 (Pubitemid 29350288)
-
(1999)
Seminars in Thrombosis and Hemostasis
, vol.25
, Issue.SUPPL. 2
, pp. 25-28
-
-
Caplain, H.1
Donat, F.2
Gaud, C.3
Necciari, J.4
-
35
-
-
33749339075
-
Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
-
DOI 10.1182/blood-2006-04-013052
-
J.S. Hulot, A. Bura, E. Villard, M. Azizi, V. Remones, C. Goyenvalle, M. Aiach, P. Lechat, and P. Gaussem Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects Blood 108 2006 2244 2247 (Pubitemid 44497506)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2244-2247
-
-
Hulot, J.-S.1
Bura, A.2
Villard, E.3
Azizi, M.4
Remones, V.5
Goyenvalle, C.6
Aiach, M.7
Lechat, P.8
Gaussem, P.9
-
37
-
-
0028260641
-
The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
-
S.M. de Morais, G.R. Wilkinson, J. Blaisdell, K. Nakamura, U.A. Meyer, and J.A. Goldstein The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans J Biol Chem 269 1994 15419 15422
-
(1994)
J Biol Chem
, vol.269
, pp. 15419-15422
-
-
De Morais, S.M.1
Wilkinson, G.R.2
Blaisdell, J.3
Nakamura, K.4
Meyer, U.A.5
Goldstein, J.A.6
-
38
-
-
0028044085
-
Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese
-
S.M. De Morais, G.R. Wilkinson, J. Blaisdell, U.A. Meyer, K. Nakamura, and J.A. Goldstein Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese Mol Pharmacol 46 1994 594 598 (Pubitemid 24334747)
-
(1994)
Molecular Pharmacology
, vol.46
, Issue.4
, pp. 594-598
-
-
De Morais, S.M.F.1
Wilkinson, G.R.2
Blaisdell, J.3
Meyer, U.A.4
Nakamura, K.5
Goldstein, J.A.6
-
39
-
-
30344457586
-
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
-
DOI 10.1016/j.clpt.2005.10.002, PII S0009923605004613
-
S.C. Sim, C. Risinger, M.L. Dahl, E. Aklillu, M. Christensen, L. Bertilsson, and M. Ingelman-Sundberg A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants Clin Pharmacol Ther 79 2006 103 113 (Pubitemid 43069582)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.79
, Issue.1
, pp. 103-113
-
-
Sim, S.C.1
Risinger, C.2
Dahl, M.-L.3
Aklillu, E.4
Christensen, M.5
Bertilsson, L.6
Ingelman-Sundberg, M.7
-
40
-
-
15444340367
-
A new genetic defect in human CYP2C19: Mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin
-
R.J. Ferguson, S.M. De Morais, S. Benhamou, C. Bouchardy, J. Blaisdell, G. Ibeanu, G.R. Wilkinson, T.C. Sarich, J.M. Wright, P. Dayer, and J.A. Goldstein A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin J Pharmacol Exp Ther 284 1998 356 361 (Pubitemid 28109566)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.284
, Issue.1
, pp. 356-361
-
-
Ferguson, R.J.1
De Morais, S.M.F.2
Benhamou, S.3
Bouchardy, C.4
Blaisdell, J.5
Ibeanu, G.6
Wilkinson, G.R.7
Sarich, T.C.8
Wright, J.M.9
Dayer, P.10
Goldstein, J.A.11
-
41
-
-
8244249473
-
Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele
-
Z.S. Xiao, J.A. Goldstein, H.G. Xie, J. Blaisdell, W. Wang, C.H. Jiang, F.X. Yan, N. He, S.L. Huang, Z.H. Xu, and H.H. Zhou Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele J Pharmacol Exp Ther 281 1997 604 609 (Pubitemid 27203121)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.281
, Issue.1
, pp. 604-609
-
-
Xiao, Z.-S.1
Goldstein, J.A.2
Xie, H.-G.3
Blaisdell, J.4
Wang, W.5
Jiang, C.-H.6
Yan, F.-X.7
He, N.8
Huang, S.-L.9
Xu, Z.-H.10
Zhou, H.-H.11
-
42
-
-
15644372745
-
An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians
-
G.C. Ibeanu, J. Blaisdell, B.I. Ghanayem, C. Beyeler, S. Benhamou, C. Bouchardy, G.R. Wilkinson, P. Dayer, A.K. Daly, and J.A. Goldstein An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians Pharmacogenetics 8 1998 129 135 (Pubitemid 28227321)
-
(1998)
Pharmacogenetics
, vol.8
, Issue.2
, pp. 129-135
-
-
Ibeanu, G.C.1
Blaisdell, J.2
Ghanayem, B.I.3
Beyeler, C.4
Benhamou, S.5
Bouchardy, C.6
Wilkinson, G.R.7
Dayer, P.8
Daly, A.K.9
Goldstein, J.A.10
-
43
-
-
0032797302
-
A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin
-
G.C. Ibeanu, J. Blaisdell, R.J. Ferguson, B.I. Ghanayem, K. Brosen, S. Benhamou, C. Bouchardy, G.R. Wilkinson, P. Dayer, and J.A. Goldstein A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin J Pharmacol Exp Ther 290 1999 635 640 (Pubitemid 29344556)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.2
, pp. 635-640
-
-
Ibeanu, G.C.1
Blaisdell, J.2
Ferguson, R.J.3
Ghanayem, B.I.4
Brosen, K.5
Benhamou, S.6
Bouchardy, C.7
Wilkinson, G.R.8
Dayer, P.9
Goldstein, J.A.10
-
44
-
-
12244261584
-
Identification and functional characterization of new potentially defective alleles of human CYP2C19
-
DOI 10.1097/00008571-200212000-00004
-
J. Blaisdell, H. Mohrenweiser, J. Jackson, S. Ferguson, S. Coulter, B. Chanas, T. Xi, B. Ghanayem, and J.A. Goldstein Identification and functional characterization of new potentially defective alleles of human CYP2C19 Pharmacogenetics 12 2002 703 711 (Pubitemid 36054937)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.9
, pp. 703-711
-
-
Blaisdell, J.1
Mohrenweiser, H.2
Jackson, J.3
Ferguson, S.4
Coulter, S.5
Chanas, B.6
Xi, T.7
Ghanayem, B.8
Goldstein, J.A.9
-
45
-
-
38349110295
-
Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patients
-
I. Rudberg, B. Mohebi, M. Hermann, H. Refsum, and E. Molden Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patients Clin Pharmacol Ther 83 2008 322 327
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 322-327
-
-
Rudberg, I.1
Mohebi, B.2
Hermann, M.3
Refsum, H.4
Molden, E.5
-
46
-
-
70350306938
-
Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole
-
S.J. Lee, W.Y. Kim, H. Kim, J.H. Shon, S.S. Lee, and J.G. Shin Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole Drug Metab Dispos 37 2009 2262 2269
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2262-2269
-
-
Lee, S.J.1
Kim, W.Y.2
Kim, H.3
Shon, J.H.4
Lee, S.S.5
Shin, J.G.6
-
47
-
-
0036394942
-
Clinical significance of the cytochrome P450 2C19 genetic polymorphism
-
Z. Desta, X. Zhao, J.G. Shin, and D.A. Flockhart Clinical significance of the cytochrome P450 2C19 genetic polymorphism Clin Pharmacokinet 41 2002 913 958 (Pubitemid 35168437)
-
(2002)
Clinical Pharmacokinetics
, vol.41
, Issue.12
, pp. 913-958
-
-
Desta, Z.1
Zhao, X.2
Shin, J.-G.3
Flockhart, D.A.4
-
49
-
-
0033828454
-
The CYP2C19 enzyme polymorphism
-
P.J. Wedlund The CYP2C19 enzyme polymorphism Pharmacology 61 2000 174 183
-
(2000)
Pharmacology
, vol.61
, pp. 174-183
-
-
Wedlund, P.J.1
-
50
-
-
34548858712
-
Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects [4]
-
DOI 10.1111/j.1538-7836.2007.02722.x
-
P. Fontana, J.S. Hulot, P. De Moerloose, and P. Gaussem Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects J Thromb Haemost 5 2007 2153 2155 (Pubitemid 47450038)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.10
, pp. 2153-2155
-
-
Fontana, P.1
Hulot, J.-S.2
De Moerloose, P.3
Gaussem, P.4
-
51
-
-
38449103046
-
Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10+12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients
-
DOI 10.1097/FPC.0b013e3282f1b2be, PII 0121301120071200000006
-
B. Giusti, A.M. Gori, R. Marcucci, C. Saracini, I. Sestini, R. Paniccia, S. Valente, D. Antoniucci, R. Abbate, and G.F. Gensini Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients Pharmacogenet Genomics 17 2007 1057 1064 (Pubitemid 351339490)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.12
, pp. 1057-1064
-
-
Giusti, B.1
Gori, A.M.2
Marcucci, R.3
Saracini, C.4
Sestini, I.5
Paniccia, R.6
Valente, S.7
Antoniucci, D.8
Abbate, R.9
Gensini, G.F.10
-
52
-
-
45249088224
-
The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
-
K.A. Kim, P.W. Park, S.J. Hong, and J.Y. Park The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance Clin Pharmacol Ther 84 2008 236 242
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 236-242
-
-
Kim, K.A.1
Park, P.W.2
Hong, S.J.3
Park, J.Y.4
-
53
-
-
41349113774
-
Effect of cytochrome p450 polymorphisms on platelet reactivity after treatment with clopidogrel in acute coronary syndrome
-
C. Frere, T. Cuisset, P.E. Morange, J. Quilici, L. Camoin-Jau, N. Saut, D. Faille, M. Lambert, I. Juhan-Vague, J.L. Bonnet, and M.C. Alessi Effect of cytochrome p450 polymorphisms on platelet reactivity after treatment with clopidogrel in acute coronary syndrome Am J Cardiol 101 2008 1088 1093
-
(2008)
Am J Cardiol
, vol.101
, pp. 1088-1093
-
-
Frere, C.1
Cuisset, T.2
Morange, P.E.3
Quilici, J.4
Camoin-Jau, L.5
Saut, N.6
Faille, D.7
Lambert, M.8
Juhan-Vague, I.9
Bonnet, J.L.10
Alessi, M.C.11
-
54
-
-
43049179414
-
Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents
-
DOI 10.1016/j.jacc.2007.12.056, PII S0735109708008656
-
D. Trenk, W. Hochholzer, M.F. Fromm, L.E. Chialda, A. Pahl, C.M. Valina, C. Stratz, P. Schmiebusch, H.P. Bestehorn, H.J. Buttner, and F.J. Neumann Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents J Am Coll Cardiol 51 2008 1925 1934 (Pubitemid 351636443)
-
(2008)
Journal of the American College of Cardiology
, vol.51
, Issue.20
, pp. 1925-1934
-
-
Trenk, D.1
Hochholzer, W.2
Fromm, M.F.3
Chialda, L.-E.4
Pahl, A.5
Valina, C.M.6
Stratz, C.7
Schmiebusch, P.8
Bestehorn, H.-P.9
Buttner, H.J.10
Neumann, F.-J.11
-
55
-
-
67949120411
-
The CYP2C19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome
-
C. Frere, T. Cuisset, B. Gaborit, M.C. Alessi, and J.S. Hulot The CYP2C19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome J Thromb Haemost 7 2009 1409 1411
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1409-1411
-
-
Frere, C.1
Cuisset, T.2
Gaborit, B.3
Alessi, M.C.4
Hulot, J.S.5
-
56
-
-
77953896604
-
Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: A systematic meta-analysis
-
J.S. Hulot, J.P. Collet, J. Silvain, A. Pena, A. Bellemain-Appaix, O. Barthelemy, G. Cayla, F. Beygui, and G. Montalescot Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis J Am Coll Cardiol 56 2010 134 143
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 134-143
-
-
Hulot, J.S.1
Collet, J.P.2
Silvain, J.3
Pena, A.4
Bellemain-Appaix, A.5
Barthelemy, O.6
Cayla, G.7
Beygui, F.8
Montalescot, G.9
-
57
-
-
33746792912
-
Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel
-
DOI 10.1161/01.ATV.0000223867.25324.1a, PII 0004360520060800000032
-
D.J. Angiolillo, A. Fernandez-Ortiz, E. Bernardo, C. Ramirez, U. Cavallari, E. Trabetti, M. Sabate, R. Hernandez, R. Moreno, J. Escaned, F. Alfonso, C. Banuelos, M.A. Costa, T.A. Bass, P.F. Pignatti, and C. Macaya Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel Arterioscler Thromb Vasc Biol 26 2006 1895 1900 (Pubitemid 44305347)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.8
, pp. 1895-1900
-
-
Angiolillo, D.J.1
Fernandez-Ortiz, A.2
Bernardo, E.3
Ramirez, C.4
Cavallari, U.5
Trabetti, E.6
Sabate, M.7
Hernandez, R.8
Moreno, R.9
Escaned, J.10
Alfonso, F.11
Banuelos, C.12
Costa, M.A.13
Bass, T.A.14
Pignatti, P.F.15
Macaya, C.16
-
58
-
-
42549112187
-
Effect of CYP3A5*3 genotype on the pharmacokinetics and antiplatelet effect of clopidogrel in healthy subjects
-
K.A. Kim, P.W. Park, and J.Y. Park Effect of CYP3A5*3 genotype on the pharmacokinetics and antiplatelet effect of clopidogrel in healthy subjects Eur J Clin Pharmacol 64 2008 589 597
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 589-597
-
-
Kim, K.A.1
Park, P.W.2
Park, J.Y.3
-
59
-
-
33744968214
-
Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel
-
J.W. Suh, B.K. Koo, S.Y. Zhang, K.W. Park, J.Y. Cho, I.J. Jang, D.S. Lee, D.W. Sohn, M.M. Lee, and H.S. Kim Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel Cmaj 174 2006 1715 1722
-
(2006)
Cmaj
, vol.174
, pp. 1715-1722
-
-
Suh, J.W.1
Koo, B.K.2
Zhang, S.Y.3
Park, K.W.4
Cho, J.Y.5
Jang, I.J.6
Lee, D.S.7
Sohn, D.W.8
Lee, M.M.9
Kim, H.S.10
-
60
-
-
33745167304
-
12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy
-
DOI 10.1080/09537100500475844, PII N71615283440327
-
S.M. Smith, H.M. Judge, G. Peters, M. Armstrong, P. Fontana, P. Gaussem, M.E. Daly, and R.F. Storey Common sequence variations in the P2Y12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy Platelets 17 2006 250 258 (Pubitemid 43890796)
-
(2006)
Platelets
, vol.17
, Issue.4
, pp. 250-258
-
-
Smith, S.M.G.1
Judge, H.M.2
Peters, G.3
Armstrong, M.4
Fontana, P.5
Gaussem, P.6
Daly, M.E.7
Storey, R.F.8
-
61
-
-
24944465039
-
12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease
-
DOI 10.1016/j.thromres.2005.03.001, PII S0049384805001040
-
D.J. Angiolillo, A. Fernandez-Ortiz, E. Bernardo, C. Ramirez, U. Cavallari, E. Trabetti, M. Sabate, P. Jimenez-Quevedo, R. Hernandez, R. Moreno, J. Escaned, F. Alfonso, C. Banuelos, M.A. Costa, T.A. Bass, P.F. Pignatti, and C. Macaya Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease Thromb Res 116 2005 491 497 (Pubitemid 41330814)
-
(2005)
Thrombosis Research
, vol.116
, Issue.6
, pp. 491-497
-
-
Angiolillo, D.J.1
Fernandez-Ortiz, A.2
Bernardo, E.3
Ramirez, C.4
Cavallari, U.5
Trabetti, E.6
Sabate, M.7
Jimenez-Quevedo, P.8
Hernandez, R.9
Moreno, R.10
Escaned, J.11
Alfonso, F.12
Banuelos, C.13
Costa, M.A.14
Bass, T.A.15
Pignatti, P.F.16
Macaya, C.17
-
62
-
-
34548722718
-
Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome
-
DOI 10.1016/j.thromres.2007.01.012, PII S004938480700045X
-
T. Cuisset, C. Frere, J. Quilici, P.E. Morange, N. Saut, M. Lambert, L. Camoin, I.J. Vague, J.L. Bonnet, and M.C. Alessi Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome Thromb Res 120 2007 893 899 (Pubitemid 47432706)
-
(2007)
Thrombosis Research
, vol.120
, Issue.6
, pp. 893-899
-
-
Cuisset, T.1
Frere, C.2
Quilici, J.3
Morange, P.-E.4
Saut, N.5
Lambert, M.6
Camoin, L.7
Vague, I.J.8
Bonnet, J.-L.9
Alessi, M.-C.10
-
63
-
-
0042859862
-
12 gene sequence variations in healthy subjects
-
DOI 10.1161/01.CIR.0000085073.69189.88
-
P. Fontana, A. Dupont, S. Gandrille, C. Bachelot-Loza, J.L. Reny, M. Aiach, and P. Gaussem Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects Circulation 108 2003 989 995 (Pubitemid 37048230)
-
(2003)
Circulation
, vol.108
, Issue.8
, pp. 989-995
-
-
Fontana, P.1
Dupont, A.2
Gandrille, S.3
Bachelot-Loza, C.4
Reny, J.-L.5
Aiach, M.6
Gaussem, P.7
-
64
-
-
33751080762
-
Impact of P-glycoprotein on clopidogrel absorption
-
DOI 10.1016/j.clpt.2006.07.007, PII S0009923606003018
-
D. Taubert, N. von Beckerath, G. Grimberg, A. Lazar, N. Jung, T. Goeser, A. Kastrati, A. Schomig, and E. Schomig Impact of P-glycoprotein on clopidogrel absorption Clin Pharmacol Ther 80 2006 486 501 (Pubitemid 44767878)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.5
, pp. 486-501
-
-
Taubert, D.1
Von Beckerath, N.2
Grimberg, G.3
Lazar, A.4
Jung, N.5
Goeser, T.6
Kastrati, A.7
Schomig, A.8
Schomig, E.9
-
65
-
-
68149180722
-
Recent developments in clopidogrel pharmacology and their relation to clinical outcomes
-
P.A. Gurbel, M.J. Antonino, and U.S. Tantry Recent developments in clopidogrel pharmacology and their relation to clinical outcomes Expert Opin Drug Metab Toxicol 5 2009 989 1004
-
(2009)
Expert Opin Drug Metab Toxicol
, vol.5
, pp. 989-1004
-
-
Gurbel, P.A.1
Antonino, M.J.2
Tantry, U.S.3
-
66
-
-
77952400164
-
Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel
-
D. Sibbing, N. von Beckerath, T. Morath, J. Stegherr, J. Mehilli, N. Sarafoff, S. Braun, S. Schulz, A. Schomig, and A. Kastrati Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel Eur Heart J 31 2010 1205 1211
-
(2010)
Eur Heart J
, vol.31
, pp. 1205-1211
-
-
Sibbing, D.1
Von Beckerath, N.2
Morath, T.3
Stegherr, J.4
Mehilli, J.5
Sarafoff, N.6
Braun, S.7
Schulz, S.8
Schomig, A.9
Kastrati, A.10
-
67
-
-
68049115736
-
Drug interaction between clopidogrel and proton pump inhibitors
-
S.C. Khalique, and A. Cheng-Lai Drug interaction between clopidogrel and proton pump inhibitors Cardiol Rev 17 2009 198 200
-
(2009)
Cardiol Rev
, vol.17
, pp. 198-200
-
-
Khalique, S.C.1
Cheng-Lai, A.2
-
70
-
-
79959978247
-
Platelet Function and Antiplatelet Therapy in Cardiovascular Disease: Implications of Genetic Polymorphisms
-
[pii] [Epub ahead of print]
-
J. Shanker, A.Y. Gasparyan, G.D. Kitas, and V.V. Kakkar Platelet Function and Antiplatelet Therapy in Cardiovascular Disease: Implications of Genetic Polymorphisms Curr Vasc Pharmacol Feb. 14 2011 doi:BSP/CVP/E-Pub/0000138 [pii] [Epub ahead of print]
-
(2011)
Curr Vasc Pharmacol
-
-
Shanker, J.1
Gasparyan, A.Y.2
Kitas, G.D.3
Kakkar, V.V.4
-
71
-
-
0034762075
-
Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement [1]
-
I. Muller, M. Seyfarth, S. Rudiger, B. Wolf, G. Pogatsa-Murray, A. Schomig, and M. Gawaz Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement Heart 85 2001 92 93 (Pubitemid 32973418)
-
(2001)
Heart
, vol.85
, Issue.1
, pp. 92-93
-
-
Muller, I.1
Seyfarth, M.2
Rudiger, S.3
Wolf, B.4
Pogatsa-Murray, G.5
Schomig, A.6
Gawaz, M.7
-
72
-
-
7544239072
-
High clopidogrel loading dose during coronary stenting: Effects on drug response and interindividual variability
-
DOI 10.1016/j.ehj.2004.07.036, PII S0195668X04005512
-
D.J. Angiolillo, A. Fernandez-Ortiz, E. Bernardo, C. Ramirez, M. Sabate, C. Banuelos, R. Hernandez-Antolin, J. Escaned, R. Moreno, F. Alfonso, and C. Macaya High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability Eur Heart J 25 2004 1903 1910 (Pubitemid 39452607)
-
(2004)
European Heart Journal
, vol.25
, Issue.21
, pp. 1903-1910
-
-
Angiolillo, D.J.1
Fernandez-Ortiz, A.2
Bernardo, E.3
Ramirez, C.4
Sabate, M.5
Banuelos, C.6
Hernandez-Antolin, R.7
Escaned, J.8
Moreno, R.9
Alfonso, F.10
Macaya, C.11
-
73
-
-
66349133650
-
Cytochrome P450 genetic polymorphisms and the response to prasugrel: Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
-
J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, R.D. Hockett, J.T. Brandt, J.R. Walker, E.M. Antman, W.L. Macias, E. Braunwald, and M.S. Sabatine Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes Circulation 119 2009 2553 2560
-
(2009)
Circulation
, vol.119
, pp. 2553-2560
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
Walker, J.R.7
Antman, E.M.8
MacIas, W.L.9
Braunwald, E.10
Sabatine, M.S.11
-
74
-
-
74549137908
-
New P2Y(12) inhibitors
-
M. Cattaneo New P2Y(12) inhibitors Circulation 121 2010 171 179
-
(2010)
Circulation
, vol.121
, pp. 171-179
-
-
Cattaneo, M.1
-
75
-
-
77950508416
-
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: The RESPOND study
-
P.A. Gurbel, K.P. Bliden, K. Butler, M.J. Antonino, C. Wei, R. Teng, L. Rasmussen, R.F. Storey, T. Nielsen, J.W. Eikelboom, G. Sabe-Affaki, S. Husted, D.J. Kereiakes, D. Henderson, D.V. Patel, and U.S. Tantry Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study Circulation 121 2010 1188 1199
-
(2010)
Circulation
, vol.121
, pp. 1188-1199
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
Antonino, M.J.4
Wei, C.5
Teng, R.6
Rasmussen, L.7
Storey, R.F.8
Nielsen, T.9
Eikelboom, J.W.10
Sabe-Affaki, G.11
Husted, S.12
Kereiakes, D.J.13
Henderson, D.14
Patel, D.V.15
Tantry, U.S.16
-
76
-
-
73149118496
-
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: First experience in patients
-
P.A. Gurbel, K.P. Bliden, M.J. Antonino, G. Stephens, D.D. Gretler, M.M. Jurek, R.E. Pakyz, A.R. Shuldiner, P.B. Conley, and U.S. Tantry The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients J Thromb Haemost 8 2010 43 53
-
(2010)
J Thromb Haemost
, vol.8
, pp. 43-53
-
-
Gurbel, P.A.1
Bliden, K.P.2
Antonino, M.J.3
Stephens, G.4
Gretler, D.D.5
Jurek, M.M.6
Pakyz, R.E.7
Shuldiner, A.R.8
Conley, P.B.9
Tantry, U.S.10
-
77
-
-
79551534844
-
Late-breaking clinical trials presented at the American Heart Association Congress in Chicago 2010
-
C. Gensch, U. Hoppe, M. Bohm, and U. Laufs Late-breaking clinical trials presented at the American Heart Association Congress in Chicago 2010 Clin Res Cardiol 100 2010 1 9
-
(2010)
Clin Res Cardiol
, vol.100
, pp. 1-9
-
-
Gensch, C.1
Hoppe, U.2
Bohm, M.3
Laufs, U.4
-
78
-
-
77649230712
-
Genetic causes of clopidogrel nonresponsiveness: Which ones really count?
-
K.M. Momary, M.P. Dorsch, and E.R. Bates Genetic causes of clopidogrel nonresponsiveness: which ones really count? Pharmacotherapy 30 2010 265 274
-
(2010)
Pharmacotherapy
, vol.30
, pp. 265-274
-
-
Momary, K.M.1
Dorsch, M.P.2
Bates, E.R.3
-
79
-
-
80052642128
-
Variability in response to clopidogrel: How important are pharmacogenetics and drug interactions?
-
T.K. Ma, Y.Y. Lam, V.P. Tan, and B.P. Yan Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions? Br J Clin Pharmacol 72 2011 697 706
-
(2011)
Br J Clin Pharmacol
, vol.72
, pp. 697-706
-
-
Ma, T.K.1
Lam, Y.Y.2
Tan, V.P.3
Yan, B.P.4
|