Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms

International Journal of Legal Medicine

Volumn 122, Issue 2, 2008, Pages 149-155

  Thieme, Detlef ^a,b   Rolf, Burkhard ^a   Sachs, Hans ^a,b   Schmid, Dagmar ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Forensic Toxicological Centre   (Germany)

Author keywords

Amitriptyline; CYP polymorphism; Drug facilitated crime; Pharmacogenetics; Segmental hair analysis

Indexed keywords

AMITRIPTYLINE; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6;

ALLELE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMETHYLATION; DNA POLYMORPHISM; DRUG METABOLISM; GENETIC VARIABILITY; HAIR ANALYSIS; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOGENETICS; PRIORITY JOURNAL;

ALLELES; AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ARYL HYDROCARBON HYDROXYLASES; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP2D6; FORENSIC TOXICOLOGY; GENOTYPE; HAIR; HUMANS; MASS SPECTROMETRY; NORTRIPTYLINE; POLYMORPHISM, GENETIC;

EID: 38649126903     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-007-0184-4     Document Type: Article

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