-
1
-
-
42749087763
-
The mitochondrial impairment, oxidative stress and neurodegeneration connection:reality or just an attractive hypothesis?
-
Fukui, H. and Moraes, C.T. (2008) The mitochondrial impairment, oxidative stress and neurodegeneration connection:reality or just an attractive hypothesis? Trends Neurosci., 31, 251-256.
-
(2008)
Trends Neurosci.
, vol.31
, pp. 251-256
-
-
Fukui, H.1
Moraes, C.T.2
-
2
-
-
77956224679
-
The Alzheimer's disease mitochondrial cascade hypothesis
-
Swerdlow, R.H., Burns, J.M. and Khan, S.M. (2010) The Alzheimer's disease mitochondrial cascade hypothesis. J. Alzheimers Dis., 20(Suppl. 2), S265-S279.
-
(2010)
J. Alzheimers Dis.
, vol.20
, pp. S265-S279
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
3
-
-
77956206298
-
A mitocentric view of Alzheimer's disease suggests multi-faceted treatments
-
Gibson, G.E. and Shi, Q. (2010) A mitocentric view of Alzheimer's disease suggests multi-faceted treatments. J. Alzheimers Dis., 20(Suppl. 2), S591-S607.
-
(2010)
J. Alzheimers Dis.
, vol.20
, pp. S591-S607
-
-
Gibson, G.E.1
Shi, Q.2
-
4
-
-
33646035489
-
Mild cognitive impairment.
-
Gauthier, S., Reisberg, B., Zaudig, M., Petersen, R.C., Ritchie, K., Broich, K., Belleville, S., Brodaty, H., Bennett, D., Chertkow, H. et al. (2006) Mild cognitive impairment. Lancet, 367, 1262-1270.
-
(2006)
Lancet
, vol.367
, pp. 1262-1270
-
-
Gauthier, S.1
Reisberg, B.2
Zaudig, M.3
Petersen, R.C.4
Ritchie, K.5
Broich, K.6
Belleville, S.7
Brodaty, H.8
Bennett, D.9
Chertkow, H.10
-
5
-
-
17844364259
-
Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD.
-
Mosconi, L. (2005) Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD. Eur. J. Nucl. Med. Mol. Imaging, 32, 486-510.
-
(2005)
Eur. J. Nucl. Med. Mol. Imaging
, vol.32
, pp. 486-510
-
-
Mosconi, L.1
-
6
-
-
33746256557
-
Mitochondrial alterations in Alzheimer's disease.
-
Baloyannis, S.J. (2006) Mitochondrial alterations in Alzheimer's disease. J. Alzheimers Dis., 9, 119-126.
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 119-126
-
-
Baloyannis, S.J.1
-
7
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease.
-
Hirai, K., Aliev, G., Nunomura, A., Fujioka, H., Russell, R.L., Atwood, C.S., Johnson, A.B., Kress, Y., Vinters, H.V., Tabaton, M. et al. (2001) Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci., 21, 3017-3023.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
-
8
-
-
34249881080
-
Autophagocytosis of mitochondria is prominent in Alzheimer disease.
-
Moreira, P.I., Siedlak, S.L.,Wang, X., Santos,M.S., Oliveira, C.R., Tabaton, M., Nunomura, A., Szweda, L.I., Aliev, G., Smith, M.A. et al. (2007) Autophagocytosis of mitochondria is prominent in Alzheimer disease. J. Neuropathol. Exp. Neurol., 66, 525-532.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 525-532
-
-
Moreira, P.I.1
Siedlak, S.L.2
Wang, X.3
Santos, M.S.4
Oliveira, C.R.5
Tabaton, M.6
Nunomura, A.7
Szweda, L.I.8
Aliev, G.9
Smith, M.A.10
-
9
-
-
84861674629
-
Mitochondria as a central sensor for axonal degenerative stimuli.
-
Court, F.A. and Coleman, M.P. (2012) Mitochondria as a central sensor for axonal degenerative stimuli. Trends Neurosci., 35, 364-372.
-
(2012)
Trends Neurosci.
, vol.35
, pp. 364-372
-
-
Court, F.A.1
Coleman, M.P.2
-
10
-
-
84860176236
-
Synaptic mitochondrial pathology in Alzheimer's disease.
-
Du, H., Guo, L. and Yan, S.S. (2012) Synaptic mitochondrial pathology in Alzheimer's disease. Antioxid. Redox. Signal, 16, 1467-1475.
-
(2012)
Antioxid. Redox. Signal
, vol.16
, pp. 1467-1475
-
-
Du, H.1
Guo, L.2
Yan, S.S.3
-
11
-
-
84882738357
-
Amyloid beta-induced glycogen synthase kinase 3beta phosphorylated VDAC1 in Alzheimer's disease:implications for synaptic dysfunction and neuronal damage.
-
Reddy, P.H. (2013) Amyloid beta-induced glycogen synthase kinase 3beta phosphorylated VDAC1 in Alzheimer's disease:implications for synaptic dysfunction and neuronal damage. Biochim. Biophys. Acta., 1832, 1913-1921.
-
(2013)
Biochim. Biophys. Acta.
, vol.1832
, pp. 1913-1921
-
-
Reddy, P.H.1
-
12
-
-
77953877676
-
A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease
-
Chu, C.T. (2010) A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease. Hum. Mol. Genet., 19, R28-R37.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. R28-R37
-
-
Chu, C.T.1
-
13
-
-
84910141948
-
Mitochondrial dynamics and inheritance during cell division, development and disease.
-
Mishra, P. and Chan, D.C. (2014) Mitochondrial dynamics and inheritance during cell division, development and disease. Nat. Rev. Mol. Cell Biol., 15, 634-646.
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 634-646
-
-
Mishra, P.1
Chan, D.C.2
-
14
-
-
84897567836
-
Mitochondrial trafficking and anchoring in neurons: New insight and implications.
-
Sheng, Z.H. (2014) Mitochondrial trafficking and anchoring in neurons: New insight and implications. J. Cell Biol., 204, 1087-1098.
-
(2014)
J. Cell Biol.
, vol.204
, pp. 1087-1098
-
-
Sheng, Z.H.1
-
15
-
-
84856056846
-
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.
-
Sheng, Z.H. and Cai, Q. (2012) Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat. Rev. Neurosci., 13, 77-93.
-
(2012)
Nat. Rev. Neurosci.
, vol.13
, pp. 77-93
-
-
Sheng, Z.H.1
Cai, Q.2
-
17
-
-
81255190781
-
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
-
Calkins, M.J., Manczak, M., Mao, P., Shirendeb, U. and Reddy, P.H. (2011) Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum. Mol. Genet., 20, 4515-4529.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4515-4529
-
-
Calkins, M.J.1
Manczak, M.2
Mao, P.3
Shirendeb, U.4
Reddy, P.H.5
-
18
-
-
84863245760
-
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease
-
Trushina, E., Nemutlu, E., Zhang, S., Christensen, T., Camp, J., Mesa, J., Siddiqui, A., Tamura, Y., Sesaki, H.,Wengenack, T.M. et al. (2012) Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. PLoS One, 7, e32737.
-
(2012)
PLoS One
, vol.7
, pp. e32737
-
-
Trushina, E.1
Nemutlu, E.2
Zhang, S.3
Christensen, T.4
Camp, J.5
Mesa, J.6
Siddiqui, A.7
Tamura, Y.8
Sesaki, H.9
Wengenack, T.M.10
-
19
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
-
Devi, L., Prabhu, B.M., Galati, D.F., Avadhani, N.G. and Anandatheerthavarada, H.K. (2006) Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. J. Neurosci., 26, 9057-9068.
-
(2006)
J. Neurosci.
, vol.26
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
20
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
-
Du, H., Guo, L., Yan, S., Sosunov, A.A., McKhann, G.M. and Yan, S.S. (2010) Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model. Proc. Natl Acad. Sci. USA, 107, 18670-18675.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 18670-18675
-
-
Du, H.1
Guo, L.2
Yan, S.3
Sosunov, A.A.4
McKhann, G.M.5
Yan, S.S.6
-
21
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
-
Manczak, M., Calkins, M.J. and Reddy, P.H. (2011) Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum. Mol. Genet., 20, 2495-2509.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
22
-
-
58049218922
-
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
-
Wang, X., Su, B., Siedlak, S.L., Moreira, P.I., Fujioka, H., Wang, Y., Casadesus, G. and Zhu, X. (2008) Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc. Natl Acad. Sci. USA, 105, 19318-19323.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
23
-
-
1642499152
-
Betaamyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.
-
Abramov, A.Y., Canevari, L. and Duchen, M.R. (2004) Betaamyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J. Neurosci., 24, 565-575.
-
(2004)
J. Neurosci.
, vol.24
, pp. 565-575
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
24
-
-
0030966546
-
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.
-
Keller, J.N., Pang, Z., Geddes, J.W., Begley, J.G., Germeyer, A., Waeg, G. and Mattson, M.P. (1997) Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem., 69, 273-284.
-
(1997)
J. Neurochem.
, vol.69
, pp. 273-284
-
-
Keller, J.N.1
Pang, Z.2
Geddes, J.W.3
Begley, J.G.4
Germeyer, A.5
Waeg, G.6
Mattson, M.P.7
-
25
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
-
Manczak, M., Anekonda, T.S., Henson, E., Park, B.S., Quinn, J. and Reddy, P.H. (2006) Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum. Mol. Genet., 15, 1437-1449.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
26
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
-
Du,H.,Guo, L., Fang, F., Chen,D., Sosunov,A.A.,McKhann,G.M., Yan, Y., Wang, C., Zhang, H., Molkentin, J.D. et al. (2008) Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat. Med., 14, 1097-1105.
-
(2008)
Nat. Med.
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
Yan, Y.7
Wang, C.8
Zhang, H.9
Molkentin, J.D.10
-
27
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
-
Lustbader, J.W., Cirilli, M., Lin, C., Xu, H.W., Takuma, K.,Wang, N., Caspersen, C., Chen, X., Pollak, S., Chaney, M. et al. (2004) ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science, 304, 448-452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
-
28
-
-
0032487648
-
Amyloid betapeptide induces apoptosis-related events in synapses and dendrites.
-
Mattson, M.P., Partin, J. and Begley, J.G. (1998) Amyloid betapeptide induces apoptosis-related events in synapses and dendrites. Brain Res., 807, 167-176.
-
(1998)
Brain Res.
, vol.807
, pp. 167-176
-
-
Mattson, M.P.1
Partin, J.2
Begley, J.G.3
-
29
-
-
0034213718
-
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.
-
Mucke, L., Masliah, E., Yu, G.Q., Mallory, M., Rockenstein, E.M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K. and McConlogue, L. (2000) High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci., 20, 4050-4058.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, D.8
Johnson-Wood, K.9
McConlogue, L.10
-
30
-
-
84858701257
-
Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons.
-
Cai, Q., Zakaria, H.M., Simone, A. and Sheng, Z.H. (2012) Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr. Biol., 22, 545-552.
-
(2012)
Curr. Biol.
, vol.22
, pp. 545-552
-
-
Cai, Q.1
Zakaria, H.M.2
Simone, A.3
Sheng, Z.H.4
-
31
-
-
29644440011
-
Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease
-
Jankowsky, J.L., Slunt, H.H., Gonzales, V., Savonenko, A.V., Wen, J.C., Jenkins, N.A., Copeland, N.G., Younkin, L.H., Lester, H.A., Younkin, S.G. et al. (2005) Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. PLoS Med., 2, e355.
-
(2005)
PLoS Med.
, vol.2
, pp. e355
-
-
Jankowsky, J.L.1
Slunt, H.H.2
Gonzales, V.3
Savonenko, A.V.4
Wen, J.C.5
Jenkins, N.A.6
Copeland, N.G.7
Younkin, L.H.8
Lester, H.A.9
Younkin, S.G.10
-
32
-
-
24944534881
-
Syntabulinmediated anterograde transport of mitochondria along neuronal processes.
-
Cai, Q., Gerwin, C. and Sheng, Z.H. (2005) Syntabulinmediated anterograde transport of mitochondria along neuronal processes. J. Cell Biol., 170, 959-969.
-
(2005)
J. Cell Biol.
, vol.170
, pp. 959-969
-
-
Cai, Q.1
Gerwin, C.2
Sheng, Z.H.3
-
33
-
-
0025471534
-
Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation.
-
Sims, N.R. (1990) Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation. J. Neurochem., 55, 698-707.
-
(1990)
J. Neurochem.
, vol.55
, pp. 698-707
-
-
Sims, N.R.1
-
34
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
-
Chan, N.C., Salazar, A.M., Pham, A.H., Sweredoski, M.J., Kolawa, N.J., Graham, R.L., Hess, S. and Chan, D.C. (2011) Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet., 20, 1726-1737.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
Hess, S.7
Chan, D.C.8
-
35
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
-
Yoshii, S.R., Kishi, C., Ishihara, N. and Mizushima, N. (2011) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J. Biol. Chem., 286, 19630-19640.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
36
-
-
84885176082
-
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
-
Chu, C.T., Ji, J., Dagda, R.K., Jiang, J.F., Tyurina, Y.Y., Kapralov, A.A., Tyurin, V.A., Yanamala, N., Shrivastava, I.H., Mohammadyani, D. et al. (2013) Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nat. Cell Biol., 15, 1197-1205.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 1197-1205
-
-
Chu, C.T.1
Ji, J.2
Dagda, R.K.3
Jiang, J.F.4
Tyurina, Y.Y.5
Kapralov, A.A.6
Tyurin, V.A.7
Yanamala, N.8
Shrivastava, I.H.9
Mohammadyani, D.10
-
37
-
-
51349110166
-
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
-
Hansson Petersen, C.A., Alikhani, N., Behbahani, H., Wiehager, B., Pavlov, P.F., Alafuzoff, I., Leinonen, V., Ito, A.,Winblad, B., Glaser, E. et al. (2008) The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc. Natl Acad. Sci. USA, 105, 13145-13150.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 13145-13150
-
-
Hansson Petersen, C.A.1
Alikhani, N.2
Behbahani, H.3
Wiehager, B.4
Pavlov, P.F.5
Alafuzoff, I.6
Leinonen, V.7
Ito, A.8
Winblad, B.9
Glaser, E.10
-
38
-
-
84877337663
-
Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.
-
Hedskog, L., Pinho, C.M., Filadi, R., Ronnback, A., Hertwig, L., Wiehager, B., Larssen, P., Gellhaar, S., Sandebring, A., Westerlund, M. et al. (2013) Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models. Proc. Natl Acad. Sci. USA, 110, 7916-7921.
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 7916-7921
-
-
Hedskog, L.1
Pinho, C.M.2
Filadi, R.3
Ronnback, A.4
Hertwig, L.5
Wiehager, B.6
Larssen, P.7
Gellhaar, S.8
Sandebring, A.9
Westerlund, M.10
-
39
-
-
84886925692
-
Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model.
-
Xie, H., Guan, J., Borrelli, L.A., Xu, J., Serrano-Pozo, A. and Bacskai, B.J. (2013) Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model. J. Neurosci., 33, 17042-17051.
-
(2013)
J. Neurosci.
, vol.33
, pp. 17042-17051
-
-
Xie, H.1
Guan, J.2
Borrelli, L.A.3
Xu, J.4
Serrano-Pozo, A.5
Bacskai, B.J.6
-
40
-
-
84903179483
-
The mitochondrial deubiquitinase USP30 opposes parkinmediated mitophagy.
-
Bingol, B., Tea, J.S., Phu, L., Reichelt, M., Bakalarski, C.E., Song, Q., Foreman, O., Kirkpatrick, D.S. and Sheng, M. (2014) The mitochondrial deubiquitinase USP30 opposes parkinmediated mitophagy. Nature, 510, 370-375.
-
(2014)
Nature
, vol.510
, pp. 370-375
-
-
Bingol, B.1
Tea, J.S.2
Phu, L.3
Reichelt, M.4
Bakalarski, C.E.5
Song, Q.6
Foreman, O.7
Kirkpatrick, D.S.8
Sheng, M.9
-
41
-
-
84901407276
-
Lysine 27 ubiquitination of the mitochondrial transport protein miro is dependent on serine 65 of the parkin ubiquitin ligase.
-
Birsa, N., Norkett, R., Wauer, T., Mevissen, T.E., Wu, H.C., Foltynie, T., Bhatia, K., Hirst, W.D., Komander, D., Plun-Favreau, H. et al. (2014) Lysine 27 ubiquitination of the mitochondrial transport protein miro is dependent on serine 65 of the parkin ubiquitin ligase. J. Biol. Chem., 289, 14569-14582.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 14569-14582
-
-
Birsa, N.1
Norkett, R.2
Wauer, T.3
Mevissen, T.E.4
Wu, H.C.5
Foltynie, T.6
Bhatia, K.7
Hirst, W.D.8
Komander, D.9
Plun-Favreau, H.10
-
42
-
-
84859237566
-
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
-
Liu, S., Sawada, T., Lee, S., Yu,W., Silverio, G., Alapatt, P., Millan, I., Shen, A., Saxton, W., Kanao, T. et al. (2012) Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet., 8, e1002537.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1002537
-
-
Liu, S.1
Sawada, T.2
Lee, S.3
Yu, W.4
Silverio, G.5
Alapatt, P.6
Millan, I.7
Shen, A.8
Saxton, W.9
Kanao, T.10
-
43
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
-
Wang, X.,Winter, D., Ashrafi, G., Schlehe, J.,Wong, Y.L., Selkoe, D., Rice, S., Steen, J., LaVoie, M.J. and Schwarz, T.L. (2011) PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell, 147, 893-906.
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
LaVoie, M.J.9
Schwarz, T.L.10
-
44
-
-
77957325618
-
Snapin-regulated late endosomal transport is critical for efficient autophagy-lysosomal function in neurons.
-
Cai, Q., Lu, L., Tian, J.H., Zhu, Y.B., Qiao, H. and Sheng, Z.H. (2010) Snapin-regulated late endosomal transport is critical for efficient autophagy-lysosomal function in neurons. Neuron, 68, 73-86.
-
(2010)
Neuron
, vol.68
, pp. 73-86
-
-
Cai, Q.1
Lu, L.2
Tian, J.H.3
Zhu, Y.B.4
Qiao, H.5
Sheng, Z.H.6
-
45
-
-
84892504040
-
Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons.
-
Ye, X. and Cai, Q. (2014) Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons. Cell Rep., 6, 24-31.
-
(2014)
Cell Rep.
, vol.6
, pp. 24-31
-
-
Ye, X.1
Cai, Q.2
-
46
-
-
79957663035
-
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy.
-
Lee, S., Sato, Y. and Nixon, R.A. (2011) Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy. J. Neurosci., 31, 7817-7830.
-
(2011)
J. Neurosci.
, vol.31
, pp. 7817-7830
-
-
Lee, S.1
Sato, Y.2
Nixon, R.A.3
-
47
-
-
33748744258
-
Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.
-
Shukkur, E.A., Shimohata, A., Akagi, T., Yu, W., Yamaguchi, M., Murayama, M., Chui, D., Takeuchi, T., Amano, K., Subramhanya, K.H. et al. (2006) Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome. Hum. Mol. Genet., 15, 2752-2762.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2752-2762
-
-
Shukkur, E.A.1
Shimohata, A.2
Akagi, T.3
Yu, W.4
Yamaguchi, M.5
Murayama, M.6
Chui, D.7
Takeuchi, T.8
Amano, K.9
Subramhanya, K.H.10
-
48
-
-
33749854516
-
Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.
-
Rui, Y., Tiwari, P., Xie, Z. and Zheng, J.Q. (2006) Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons. J. Neurosci., 26, 10480-10487.
-
(2006)
J. Neurosci.
, vol.26
, pp. 10480-10487
-
-
Rui, Y.1
Tiwari, P.2
Xie, Z.3
Zheng, J.Q.4
-
49
-
-
77957737750
-
Tau reduction prevents Abeta-induced defects in axonal transport
-
Vossel, K.A., Zhang, K., Brodbeck, J., Daub, A.C., Sharma, P., Finkbeiner, S., Cui, B. and Mucke, L. (2010) Tau reduction prevents Abeta-induced defects in axonal transport. Science, 330, 198.
-
(2010)
Science
, vol.330
, pp. 198
-
-
Vossel, K.A.1
Zhang, K.2
Brodbeck, J.3
Daub, A.C.4
Sharma, P.5
Finkbeiner, S.6
Cui, B.7
Mucke, L.8
-
50
-
-
84906861963
-
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.
-
Ashrafi, G., Schlehe, J.S., LaVoie, M.J. and Schwarz, T.L. (2014) Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J. Cell Biol., 206, 655-670.
-
(2014)
J. Cell Biol.
, vol.206
, pp. 655-670
-
-
Ashrafi, G.1
Schlehe, J.S.2
LaVoie, M.J.3
Schwarz, T.L.4
-
51
-
-
84864873195
-
Long time-lapse imaging reveals unique features of PARK2/Parkin-mediated mitophagy in mature cortical neurons.
-
Cai, Q., Zakaria, H.M. and Sheng, Z.H. (2012) Long time-lapse imaging reveals unique features of PARK2/Parkin-mediated mitophagy in mature cortical neurons. Autophagy, 8, 976-978.
-
(2012)
Autophagy
, vol.8
, pp. 976-978
-
-
Cai, Q.1
Zakaria, H.M.2
Sheng, Z.H.3
-
52
-
-
35848931249
-
Increased autophagic degradation of mitochondria in Alzheimer disease.
-
Moreira, P.I., Siedlak, S.L.,Wang, X., Santos, M.S., Oliveira, C.R., Tabaton, M., Nunomura, A., Szweda, L.I., Aliev, G., Smith, M.A. et al. (2007) Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy, 3, 614-615.
-
(2007)
Autophagy
, vol.3
, pp. 614-615
-
-
Moreira, P.I.1
Siedlak, S.L.2
Wang, X.3
Santos, M.S.4
Oliveira, C.R.5
Tabaton, M.6
Nunomura, A.7
Szweda, L.I.8
Aliev, G.9
Smith, M.A.10
-
53
-
-
84857858536
-
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons.
-
Maday, S., Wallace, K.E. and Holzbaur, E.L. (2012) Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J. Cell Biol., 196, 407-417.
-
(2012)
J. Cell Biol.
, vol.196
, pp. 407-417
-
-
Maday, S.1
Wallace, K.E.2
Holzbaur, E.L.3
-
54
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
-
Nixon, R.A., Wegiel, J., Kumar, A., Yu, W.H., Peterhoff, C., Cataldo, A. and Cuervo, A.M. (2005) Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J. Neuropathol. Exp. Neurol., 64, 113-122.
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
55
-
-
26444587508
-
Macroautophagy-a novel Betaamyloid peptide-generating pathway activated in Alzheimer's disease.
-
Yu, W.H., Cuervo, A.M., Kumar, A., Peterhoff, C.M., Schmidt, S.D., Lee, J.H., Mohan, P.S., Mercken, M., Farmery, M.R., Tjernberg, L.O. et al. (2005) Macroautophagy-a novel Betaamyloid peptide-generating pathway activated in Alzheimer's disease. J. Cell Biol., 171, 87-98.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
-
56
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
-
Boland, B., Kumar, A., Lee, S., Platt, F.M., Wegiel, J., Yu, W.H. and Nixon, R.A. (2008) Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci., 28, 6926-6937.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
57
-
-
77953913051
-
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
-
Lee, J.H., Yu, W.H., Kumar, A., Lee, S., Mohan, P.S., Peterhoff, C.M., Wolfe, D.M., Martinez-Vicente, M., Massey, A.C., Sovak, G. et al. (2010) Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell, 141, 1146-1158.
-
(2010)
Cell
, vol.141
, pp. 1146-1158
-
-
Lee, J.H.1
Yu, W.H.2
Kumar, A.3
Lee, S.4
Mohan, P.S.5
Peterhoff, C.M.6
Wolfe, D.M.7
Martinez-Vicente, M.8
Massey, A.C.9
Sovak, G.10
-
58
-
-
78650716872
-
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
-
Yang, D.S., Stavrides, P., Mohan, P.S., Kaushik, S., Kumar, A., Ohno, M., Schmidt, S.D., Wesson, D., Bandyopadhyay, U., Jiang, Y. et al. (2011) Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits. Brain, 134, 258-277.
-
(2011)
Brain
, vol.134
, pp. 258-277
-
-
Yang, D.S.1
Stavrides, P.2
Mohan, P.S.3
Kaushik, S.4
Kumar, A.5
Ohno, M.6
Schmidt, S.D.7
Wesson, D.8
Bandyopadhyay, U.9
Jiang, Y.10
-
59
-
-
0028979993
-
Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro.
-
Gregori, L., Fuchs, C., Figueiredo-Pereira, M.E., Van Nostrand, W.E. and Goldgaber, D. (1995) Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro. J. Biol. Chem., 270, 19702-19708.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19702-19708
-
-
Gregori, L.1
Fuchs, C.2
Figueiredo-Pereira, M.E.3
Van Nostrand, W.E.4
Goldgaber, D.5
-
60
-
-
51449096696
-
Abeta inhibits the proteasome and enhances amyloid and tau accumulation.
-
Tseng, B.P., Green, K.N., Chan, J.L., Blurton-Jones, M. and LaFerla, F.M. (2008) Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiol. Aging, 29, 1607-1618.
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1607-1618
-
-
Tseng, B.P.1
Green, K.N.2
Chan, J.L.3
Blurton-Jones, M.4
LaFerla, F.M.5
-
61
-
-
0034131044
-
Impaired proteasome function in Alzheimer's disease.
-
Keller, J.N., Hanni, K.B. and Markesbery,W.R. (2000) Impaired proteasome function in Alzheimer's disease. J. Neurochem., 75, 436-439.
-
(2000)
J. Neurochem.
, vol.75
, pp. 436-439
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
62
-
-
0026134421
-
Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections.
-
Braak, H. and Braak, E. (1991) Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections. Brain Pathol., 1, 213-216.
-
(1991)
Brain Pathol.
, vol.1
, pp. 213-216
-
-
Braak, H.1
Braak, E.2
-
63
-
-
0018670019
-
Further observations on hippocampal neurons in dispersed cell culture.
-
Banker, G.A. and Cowan, W.M. (1979) Further observations on hippocampal neurons in dispersed cell culture. J. Comp. Neurol., 187, 469-493.
-
(1979)
J. Comp. Neurol.
, vol.187
, pp. 469-493
-
-
Banker, G.A.1
Cowan, W.M.2
-
64
-
-
37749053855
-
Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.
-
Kang, J.S., Tian, J.H., Pan, P.Y., Zald, P., Li, C., Deng, C. and Sheng, Z.H. (2008) Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell, 132, 137-148.
-
(2008)
Cell
, vol.132
, pp. 137-148
-
-
Kang, J.S.1
Tian, J.H.2
Pan, P.Y.3
Zald, P.4
Li, C.5
Deng, C.6
Sheng, Z.H.7
-
65
-
-
84864304346
-
Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons.
-
Zhou, B., Cai, Q., Xie, Y. and Sheng, Z.H. (2012) Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons. Cell Rep., 2, 42-51.
-
(2012)
Cell Rep.
, vol.2
, pp. 42-51
-
-
Zhou, B.1
Cai, Q.2
Xie, Y.3
Sheng, Z.H.4
-
66
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy.
-
Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J.A. et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8, 445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
|