Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: Implications for co-crystallization

Acta Crystallographica Section D: Biological Crystallography

Volumn 71, Issue , 2015, Pages 896-906

  Johnson, Jennifer L ^a   Entzminger, Kevin C ^b   Hyun, Jeongmin ^b   Kalyoncu, Sibel ^a   Heaner, David P ^a   Morales, Ivan A ^a   Sheppard, Aly ^a   Gumbart, James C ^a   Maynard, Jennifer A ^b   Lieberman, Raquel L ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

crystallization chaperones; Fab fragment; GPCRs; membrane proteins; barrel

Indexed keywords

EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; MEMBRANE PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; MOUSE; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; EPITOPES; IMMUNOGLOBULIN FAB FRAGMENTS; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; PROTEIN CONFORMATION; SINGLE-CHAIN ANTIBODIES;

EID: 84927583454     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S1399004715001856     Document Type: Article

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