Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 2, 2003, Pages 455-460

  Yang, Jin Kuk ^a   Park, Min S ^b   Waldo, Geoffrey S ^b   Suh, Se Won ^a  

^a Seoul National University   (South Korea)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTERONE; ASPARTIC ACID; GENE PRODUCT; HYDROXYSTEROID DEHYDROGENASE; LYSINE; MUTANT PROTEIN; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RV2002 M3 PROTEIN; SERINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CELL INCLUSION; CRYSTAL STRUCTURE; ENZYME ASSAY; ESCHERICHIA COLI; GENE OVEREXPRESSION; GENE TARGETING; GENOMICS; MOLECULAR EVOLUTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; STEROID METABOLISM;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; EVOLUTION; GENOMICS; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; POINT MUTATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ACTINOBACTERIA (CLASS); ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0037457947     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0137017100     Document Type: Article

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