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Volumn 172, Issue 9, 2015, Pages 2167-2178

Autophagy: An emerging therapeutic target in vascular diseases

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ADVANCED GLYCATION END PRODUCT; BAFILOMYCIN A1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CYTOKINE; EVEROLIMUS; GROWTH FACTOR; IMIQUIMOD; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; METFORMIN; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SIMVASTATIN; SPAUTIN 1; TREHALOSE; UNCLASSIFIED DRUG; VALPROIC ACID; CARDIOVASCULAR AGENT;

EID: 84926687110     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13052     Document Type: Review
Times cited : (65)

References (107)
  • 4
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, et al. (2008). Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 182: 685-701.
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5    Habermann, A.6
  • 5
    • 0345870065 scopus 로고    scopus 로고
    • Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice
    • Basso MD, Nambi P, Adelman SJ, (2003). Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice. Transplant Proc 35: 3136-3138.
    • (2003) Transplant Proc , vol.35 , pp. 3136-3138
    • Basso, M.D.1    Nambi, P.2    Adelman, S.J.3
  • 6
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya P, Reggiori F, Codogno P, (2013). Emerging regulation and functions of autophagy. Nat Cell Biol 15: 713-720.
    • (2013) Nat Cell Biol , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 7
    • 51449085299 scopus 로고    scopus 로고
    • The role of autophagy in mammalian development: Cell makeover rather than cell death
    • Cecconi F, Levine B, (2008). The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell 15: 344-357.
    • (2008) Dev Cell , vol.15 , pp. 344-357
    • Cecconi, F.1    Levine, B.2
  • 8
    • 84888161072 scopus 로고    scopus 로고
    • Therapeutic targeting of autophagy in disease: Biology and pharmacology
    • Cheng Y, Ren X, Hait WN, Yang JM, (2013). Therapeutic targeting of autophagy in disease: biology and pharmacology. Pharmacol Rev 65: 1162-1197.
    • (2013) Pharmacol Rev , vol.65 , pp. 1162-1197
    • Cheng, Y.1    Ren, X.2    Hait, W.N.3    Yang, J.M.4
  • 9
    • 33748469506 scopus 로고    scopus 로고
    • Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
    • Clarke MC, Figg N, Maguire JJ, Davenport AP, Goddard M, Littlewood TD, et al. (2006). Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat Med 12: 1075-1080.
    • (2006) Nat Med , vol.12 , pp. 1075-1080
    • Clarke, M.C.1    Figg, N.2    Maguire, J.J.3    Davenport, A.P.4    Goddard, M.5    Littlewood, T.D.6
  • 10
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • Codogno P, Meijer AJ, (2005). Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12 (Suppl. 2): 1509-1518.
    • (2005) Cell Death Differ , vol.12 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 11
    • 84882264646 scopus 로고    scopus 로고
    • Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release
    • Dai XY, Zhao MM, Cai Y, Guan QC, Zhao Y, Guan Y, et al. (2013). Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. Kidney Int 83: 1042-1051.
    • (2013) Kidney Int , vol.83 , pp. 1042-1051
    • Dai, X.Y.1    Zhao, M.M.2    Cai, Y.3    Guan, Q.C.4    Zhao, Y.5    Guan, Y.6
  • 12
    • 0002549377 scopus 로고
    • The lysosome
    • De Duve C, (1963). The lysosome. Sci Am 208: 64-72.
    • (1963) Sci Am , vol.208 , pp. 64-72
    • De Duve, C.1
  • 13
    • 84860153374 scopus 로고    scopus 로고
    • Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques
    • De Meyer I, Martinet W, Schrijvers DM, Timmermans JP, Bult H, De Meyer GR, (2012). Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques. Basic Res Cardiol 107: 269.
    • (2012) Basic Res Cardiol , vol.107 , pp. 269
    • De Meyer, I.1    Martinet, W.2    Schrijvers, D.M.3    Timmermans, J.P.4    Bult, H.5    De Meyer, G.R.6
  • 14
    • 79951910694 scopus 로고    scopus 로고
    • Autophagy in immunity and cell-autonomous defense against intracellular microbes
    • Deretic V, (2011). Autophagy in immunity and cell-autonomous defense against intracellular microbes. Immunol Rev 240: 92-104.
    • (2011) Immunol Rev , vol.240 , pp. 92-104
    • Deretic, V.1
  • 15
    • 84885292826 scopus 로고    scopus 로고
    • Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7 g
    • Ding Z, Wang X, Schnackenberg L, Khaidakov M, Liu S, Singla S, et al. (2013). Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7 g. Int J Cardiol 168: 1378-1385.
    • (2013) Int J Cardiol , vol.168 , pp. 1378-1385
    • Ding, Z.1    Wang, X.2    Schnackenberg, L.3    Khaidakov, M.4    Liu, S.5    Singla, S.6
  • 16
    • 79958828558 scopus 로고    scopus 로고
    • Regulation of lipid droplets by autophagy
    • Dong H, Czaja MJ, (2011). Regulation of lipid droplets by autophagy. Trends Endocrinol Metab 22: 234-240.
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 234-240
    • Dong, H.1    Czaja, M.J.2
  • 17
    • 84859420971 scopus 로고    scopus 로고
    • Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis
    • Doring Y, Manthey HD, Drechsler M, Lievens D, Megens RT, Soehnlein O, et al. (2012). Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation 125: 1673-1683.
    • (2012) Circulation , vol.125 , pp. 1673-1683
    • Doring, Y.1    Manthey, H.D.2    Drechsler, M.3    Lievens, D.4    Megens, R.T.5    Soehnlein, O.6
  • 18
    • 84906935699 scopus 로고    scopus 로고
    • Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
    • Emanuel R, Sergin I, Bhattacharya S, Turner JN, Epelman S, Settembre C, et al. (2014). Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae. Arterioscler Thromb Vasc Biol 34: 1942-1952.
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 1942-1952
    • Emanuel, R.1    Sergin, I.2    Bhattacharya, S.3    Turner, J.N.4    Epelman, S.5    Settembre, C.6
  • 19
    • 0026657363 scopus 로고
    • The role of lipid peroxidation and antioxidants in oxidative modification of LDL
    • Esterbauer H, Gebicki J, Puhl H, Jurgens G, (1992). The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med 13: 341-390.
    • (1992) Free Radic Biol Med , vol.13 , pp. 341-390
    • Esterbauer, H.1    Gebicki, J.2    Puhl, H.3    Jurgens, G.4
  • 20
  • 23
    • 78650448754 scopus 로고    scopus 로고
    • Chemical modulators of autophagy as biological probes and potential therapeutics
    • Fleming A, Noda T, Yoshimori T, Rubinsztein DC, (2011). Chemical modulators of autophagy as biological probes and potential therapeutics. Nat Chem Biol 7: 9-17.
    • (2011) Nat Chem Biol , vol.7 , pp. 9-17
    • Fleming, A.1    Noda, T.2    Yoshimori, T.3    Rubinsztein, D.C.4
  • 24
    • 84881506338 scopus 로고    scopus 로고
    • The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis
    • Ge L, Melville D, Zhang M, Schekman R, (2013). The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis. Elife 2: e00947.
    • (2013) Elife , vol.2 , pp. e00947
    • Ge, L.1    Melville, D.2    Zhang, M.3    Schekman, R.4
  • 26
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M, (2010). Oxidative stress and diabetic complications. Circ Res 107: 1058-1070.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 27
    • 84863109266 scopus 로고    scopus 로고
    • AP1 is essential for generation of autophagosomes from the trans-Golgi network
    • Guo Y, Chang C, Huang R, Liu B, Bao L, Liu W, (2012). AP1 is essential for generation of autophagosomes from the trans-Golgi network. J Cell Sci 125 (Pt 7): 1706-1715.
    • (2012) J Cell Sci , vol.125 , Issue.PT 7 , pp. 1706-1715
    • Guo, Y.1    Chang, C.2    Huang, R.3    Liu, B.4    Bao, L.5    Liu, W.6
  • 28
    • 84878772042 scopus 로고    scopus 로고
    • Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response
    • Haberzettl P, Hill BG, (2013). Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response. Redox Biol 1: 56-64.
    • (2013) Redox Biol , vol.1 , pp. 56-64
    • Haberzettl, P.1    Hill, B.G.2
  • 30
    • 0037308987 scopus 로고    scopus 로고
    • The early secretory pathway contributes to autophagy in yeast
    • Hamasaki M, Noda T, Ohsumi Y, (2003). The early secretory pathway contributes to autophagy in yeast. Cell Struct Funct 28: 49-54.
    • (2003) Cell Struct Funct , vol.28 , pp. 49-54
    • Hamasaki, M.1    Noda, T.2    Ohsumi, Y.3
  • 32
    • 0029953575 scopus 로고    scopus 로고
    • Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway
    • Harding TM, Hefner-Gravink A, Thumm M, Klionsky DJ, (1996). Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway. J Biol Chem 271: 17621-17624.
    • (1996) J Biol Chem , vol.271 , pp. 17621-17624
    • Harding, T.M.1    Hefner-Gravink, A.2    Thumm, M.3    Klionsky, D.J.4
  • 34
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He C, Klionsky DJ, (2009). Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 43: 67-93.
    • (2009) Annu Rev Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 35
    • 84880616033 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B
    • He C, Zhu H, Zhang W, Okon I, Wang Q, Li H, et al. (2013). 7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. Am J Pathol 183: 626-637.
    • (2013) Am J Pathol , vol.183 , pp. 626-637
    • He, C.1    Zhu, H.2    Zhang, W.3    Okon, I.4    Wang, Q.5    Li, H.6
  • 36
    • 84859475104 scopus 로고    scopus 로고
    • Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: The protective role of autophagy
    • Higdon AN, Benavides GA, Chacko BK, Ouyang X, Johnson MS, Landar A, et al. (2012). Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy. Am J Physiol Heart Circ Physiol 302: H1394-H1409.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302 , pp. H1394-H1409
    • Higdon, A.N.1    Benavides, G.A.2    Chacko, B.K.3    Ouyang, X.4    Johnson, M.S.5    Landar, A.6
  • 37
    • 41149116150 scopus 로고    scopus 로고
    • Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells
    • Hill BG, Haberzettl P, Ahmed Y, Srivastava S, Bhatnagar A, (2008). Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells. Biochem J 410: 525-534.
    • (2008) Biochem J , vol.410 , pp. 525-534
    • Hill, B.G.1    Haberzettl, P.2    Ahmed, Y.3    Srivastava, S.4    Bhatnagar, A.5
  • 38
    • 84858249608 scopus 로고    scopus 로고
    • ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells
    • Hu P, Lai D, Lu P, Gao J, He H, (2012). ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells. Int J Mol Med 29: 613-618.
    • (2012) Int J Mol Med , vol.29 , pp. 613-618
    • Hu, P.1    Lai, D.2    Lu, P.3    Gao, J.4    He, H.5
  • 39
    • 84892678766 scopus 로고    scopus 로고
    • Bacteria-autophagy interplay: A battle for survival
    • Huang J, Brumell JH, (2014). Bacteria-autophagy interplay: a battle for survival. Nat Rev Microbiol 12: 101-114.
    • (2014) Nat Rev Microbiol , vol.12 , pp. 101-114
    • Huang, J.1    Brumell, J.H.2
  • 40
    • 84886517584 scopus 로고    scopus 로고
    • Adenosine monophosphate-activated protein kinase is required for pulmonary artery smooth muscle cell survival and the development of hypoxic pulmonary hypertension
    • Ibe JC, Zhou Q, Chen T, Tang H, Yuan JX, Raj JU, et al. (2013). Adenosine monophosphate-activated protein kinase is required for pulmonary artery smooth muscle cell survival and the development of hypoxic pulmonary hypertension. Am J Respir Cell Mol Biol 49: 609-618.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , pp. 609-618
    • Ibe, J.C.1    Zhou, Q.2    Chen, T.3    Tang, H.4    Yuan, J.X.5    Raj, J.U.6
  • 41
    • 33747863220 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and TNF-alpha regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
    • Jia G, Cheng G, Gangahar DM, Agrawal DK, (2006). Insulin-like growth factor-1 and TNF-alpha regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells. Immunol Cell Biol 84: 448-454.
    • (2006) Immunol Cell Biol , vol.84 , pp. 448-454
    • Jia, G.1    Cheng, G.2    Gangahar, D.M.3    Agrawal, D.K.4
  • 44
    • 0032563650 scopus 로고    scopus 로고
    • Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal
    • Kockx MM, De Meyer GR, Buyssens N, Knaapen MW, Bult H, Herman AG, (1998). Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal. Circ Res 83: 378-387.
    • (1998) Circ Res , vol.83 , pp. 378-387
    • Kockx, M.M.1    De Meyer, G.R.2    Buyssens, N.3    Knaapen, M.W.4    Bult, H.5    Herman, A.G.6
  • 45
    • 84864120303 scopus 로고    scopus 로고
    • Translational evidence that impaired autophagy contributes to arterial ageing
    • LaRocca TJ, Henson GD, Thorburn A, Sindler AL, Pierce GL, Seals DR, (2012). Translational evidence that impaired autophagy contributes to arterial ageing. J Physiol 590 (Pt 14): 3305-3316.
    • (2012) J Physiol , vol.590 , Issue.PT 14 , pp. 3305-3316
    • Larocca, T.J.1    Henson, G.D.2    Thorburn, A.3    Sindler, A.L.4    Pierce, G.L.5    Seals, D.R.6
  • 47
    • 84555195856 scopus 로고    scopus 로고
    • Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
    • Lee J, Giordano S, Zhang J, (2012). Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J 441: 523-540.
    • (2012) Biochem J , vol.441 , pp. 523-540
    • Lee, J.1    Giordano, S.2    Zhang, J.3
  • 48
    • 79961102995 scopus 로고    scopus 로고
    • Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
    • Lee SJ, Kim HP, Jin Y, Choi AM, Ryter SW, (2011a). Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy 7: 829-839.
    • (2011) Autophagy , vol.7 , pp. 829-839
    • Lee, S.J.1    Kim, H.P.2    Jin, Y.3    Choi, A.M.4    Ryter, S.W.5
  • 49
    • 79952217657 scopus 로고    scopus 로고
    • Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension
    • Lee SJ, Smith A, Guo L, Alastalo TP, Li M, Sawada H, et al. (2011b). Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med 183: 649-658.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 649-658
    • Lee, S.J.1    Smith, A.2    Guo, L.3    Alastalo, T.P.4    Li, M.5    Sawada, H.6
  • 50
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • Levine B, Yuan J, (2005). Autophagy in cell death: an innocent convict? J Clin Invest 115: 2679-2688.
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 51
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW, (2011). Autophagy in immunity and inflammation. Nature 469: 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 52
  • 53
    • 79960021457 scopus 로고    scopus 로고
    • Kruppel-like factor 4 regulates macrophage polarization
    • Liao X, Sharma N, Kapadia F, Zhou G, Lu Y, Hong H, et al. (2011). Kruppel-like factor 4 regulates macrophage polarization. J Clin Invest 121: 2736-2749.
    • (2011) J Clin Invest , vol.121 , pp. 2736-2749
    • Liao, X.1    Sharma, N.2    Kapadia, F.3    Zhou, G.4    Lu, Y.5    Hong, H.6
  • 55
    • 84867041125 scopus 로고    scopus 로고
    • Angiogenesis impairment in diabetes: Role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2
    • Liu H, Yu S, Zhang H, Xu J, (2012). Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. PLoS ONE 7: e46720.
    • (2012) PLoS ONE , vol.7 , pp. e46720
    • Liu, H.1    Yu, S.2    Zhang, H.3    Xu, J.4
  • 56
    • 84862611041 scopus 로고    scopus 로고
    • TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes
    • Longatti A, Lamb CA, Razi M, Yoshimura S, Barr FA, Tooze SA, (2012). TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes. J Cell Biol 197: 659-675.
    • (2012) J Cell Biol , vol.197 , pp. 659-675
    • Longatti, A.1    Lamb, C.A.2    Razi, M.3    Yoshimura, S.4    Barr, F.A.5    Tooze, S.A.6
  • 57
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ, (2000). Atherosclerosis. Nature 407: 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 58
  • 59
    • 84871858239 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein E-deficient mice
    • Macritchie N, Grassia G, Sabir SR, Maddaluno M, Welsh P, Sattar N, et al. (2012). Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 32: 2569-2579.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2569-2579
    • Macritchie, N.1    Grassia, G.2    Sabir, S.R.3    Maddaluno, M.4    Welsh, P.5    Sattar, N.6
  • 60
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G, (2007). Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 62
    • 61949233502 scopus 로고    scopus 로고
    • Autophagy in atherosclerosis: A cell survival and death phenomenon with therapeutic potential
    • Martinet W, De Meyer GR, (2009). Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential. Circ Res 104: 304-317.
    • (2009) Circ Res , vol.104 , pp. 304-317
    • Martinet, W.1    De Meyer, G.R.2
  • 63
    • 10644244534 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells
    • Martinet W, De Bie M, Schrijvers DM, De Meyer GR, Herman AG, Kockx MM, (2004). 7-Ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 24: 2296-2301.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2296-2301
    • Martinet, W.1    De Bie, M.2    Schrijvers, D.M.3    De Meyer, G.R.4    Herman, A.G.5    Kockx, M.M.6
  • 64
    • 33646801237 scopus 로고    scopus 로고
    • Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: Implications for the stabilization of macrophage-rich atherosclerotic plaques
    • Martinet W, De Meyer GR, Timmermans JP, Herman AG, Kockx MM, (2006). Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-rich atherosclerotic plaques. J Pharmacol Exp Ther 317: 1356-1364.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 1356-1364
    • Martinet, W.1    De Meyer, G.R.2    Timmermans, J.P.3    Herman, A.G.4    Kockx, M.M.5
  • 66
    • 47249152694 scopus 로고    scopus 로고
    • Interactions between cell death induced by statins and 7-Ketocholesterol in rabbit aorta smooth muscle cells
    • Martinet W, Schrijvers DM, Timmermans JP, Bult H, (2008). Interactions between cell death induced by statins and 7-Ketocholesterol in rabbit aorta smooth muscle cells. Br J Pharmacol 154: 1236-1246.
    • (2008) Br J Pharmacol , vol.154 , pp. 1236-1246
    • Martinet, W.1    Schrijvers, D.M.2    Timmermans, J.P.3    Bult, H.4
  • 67
  • 68
    • 84896295961 scopus 로고    scopus 로고
    • MTOR inhibition: A promising strategy for stabilization of atherosclerotic plaques
    • Martinet W, De Loof H, De Meyer GR, (2014). mTOR inhibition: a promising strategy for stabilization of atherosclerotic plaques. Atherosclerosis 233: 601-607.
    • (2014) Atherosclerosis , vol.233 , pp. 601-607
    • Martinet, W.1    De Loof, H.2    De Meyer, G.R.3
  • 69
    • 79955693448 scopus 로고    scopus 로고
    • The inflammasome in atherosclerosis and type 2 diabetes
    • Masters SL, Latz E, O'Neill LA, (2011). The inflammasome in atherosclerosis and type 2 diabetes. Sci Transl Med 3: 81ps17.
    • (2011) Sci Transl Med , vol.3 , pp. 81ps17
    • Masters, S.L.1    Latz, E.2    O'Neill, L.A.3
  • 70
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima N, (2007). Autophagy: process and function. Genes Dev 21: 2861-2873.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 71
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima N, Komatsu M, (2011). Autophagy: renovation of cells and tissues. Cell 147: 728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 73
    • 79955535643 scopus 로고    scopus 로고
    • Macrophages in the pathogenesis of atherosclerosis
    • Moore KJ, Tabas I, (2011). Macrophages in the pathogenesis of atherosclerosis. Cell 145: 341-355.
    • (2011) Cell , vol.145 , pp. 341-355
    • Moore, K.J.1    Tabas, I.2
  • 74
    • 79960774898 scopus 로고    scopus 로고
    • Autophagosome precursor maturation requires homotypic fusion
    • Moreau K, Ravikumar B, Renna M, Puri C, Rubinsztein DC, (2011). Autophagosome precursor maturation requires homotypic fusion. Cell 146: 303-317.
    • (2011) Cell , vol.146 , pp. 303-317
    • Moreau, K.1    Ravikumar, B.2    Renna, M.3    Puri, C.4    Rubinsztein, D.C.5
  • 75
    • 79954417021 scopus 로고    scopus 로고
    • HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs
    • Muller C, Salvayre R, Negre-Salvayre A, Vindis C, (2011a). HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs. Cell Death Differ 18: 817-828.
    • (2011) Cell Death Differ , vol.18 , pp. 817-828
    • Muller, C.1    Salvayre, R.2    Negre-Salvayre, A.3    Vindis, C.4
  • 76
    • 79955697957 scopus 로고    scopus 로고
    • Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: Prevention by HDLs
    • Muller C, Salvayre R, Negre-Salvayre A, Vindis C, (2011b). Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs. Autophagy 7: 541-543.
    • (2011) Autophagy , vol.7 , pp. 541-543
    • Muller, C.1    Salvayre, R.2    Negre-Salvayre, A.3    Vindis, C.4
  • 77
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik E, Dixit VM, (2011). Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J Exp Med 208: 417-420.
    • (2011) J Exp Med , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 78
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. (2011). Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12: 222-230.
    • (2011) Nat Immunol , vol.12 , pp. 222-230
    • Nakahira, K.1    Haspel, J.A.2    Rathinam, V.A.3    Lee, S.J.4    Dolinay, T.5    Lam, H.C.6
  • 79
    • 34548604527 scopus 로고    scopus 로고
    • No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy
    • Nowicki M, Zabirnyk O, Duerrschmidt N, Borlak J, Spanel-Borowski K, (2007). No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy. Eur J Cell Biol 86: 605-616.
    • (2007) Eur J Cell Biol , vol.86 , pp. 605-616
    • Nowicki, M.1    Zabirnyk, O.2    Duerrschmidt, N.3    Borlak, J.4    Spanel-Borowski, K.5
  • 80
    • 79958030075 scopus 로고    scopus 로고
    • Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase
    • Ouimet M, Franklin V, Mak E, Liao X, Tabas I, Marcel YL, (2011). Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. Cell Metab 13: 655-667.
    • (2011) Cell Metab , vol.13 , pp. 655-667
    • Ouimet, M.1    Franklin, V.2    Mak, E.3    Liao, X.4    Tabas, I.5    Marcel, Y.L.6
  • 81
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • NC-IUPHAR
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl. Acids Res. 42 (Database Issue): D1098-D1106.
    • (2014) Nucl. Acids Res. , vol.42 , Issue.DATABASE ISSUE , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 82
    • 84880133893 scopus 로고    scopus 로고
    • The use of electron microscopy for the detection of autophagy in human atherosclerosis
    • Perrotta I, (2013). The use of electron microscopy for the detection of autophagy in human atherosclerosis. Micron 50: 7-13.
    • (2013) Micron , vol.50 , pp. 7-13
    • Perrotta, I.1
  • 83
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy gene-dependent clearance of apoptotic cells during embryonic development
    • Qu X, Zou Z, Sun Q, Luby-Phelps K, Cheng P, Hogan RN, et al. (2007). Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 128: 931-946.
    • (2007) Cell , vol.128 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.N.6
  • 84
    • 77955131007 scopus 로고    scopus 로고
    • Plasma membrane contributes to the formation of pre-autophagosomal structures
    • Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC, (2010). Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat Cell Biol 12: 747-757.
    • (2010) Nat Cell Biol , vol.12 , pp. 747-757
    • Ravikumar, B.1    Moreau, K.2    Jahreiss, L.3    Puri, C.4    Rubinsztein, D.C.5
  • 85
    • 84859448447 scopus 로고    scopus 로고
    • Autophagy links inflammasomes to atherosclerotic progression
    • Razani B, Feng C, Coleman T, Emanuel R, Wen H, Hwang S, et al. (2012). Autophagy links inflammasomes to atherosclerotic progression. Cell Metab 15: 534-544.
    • (2012) Cell Metab , vol.15 , pp. 534-544
    • Razani, B.1    Feng, C.2    Coleman, T.3    Emanuel, R.4    Wen, H.5    Hwang, S.6
  • 87
    • 84876237304 scopus 로고    scopus 로고
    • PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress
    • Salabei JK, Cummins TD, Singh M, Jones SP, Bhatnagar A, Hill BG, (2013). PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress. Biochem J 451: 375-388.
    • (2013) Biochem J , vol.451 , pp. 375-388
    • Salabei, J.K.1    Cummins, T.D.2    Singh, M.3    Jones, S.P.4    Bhatnagar, A.5    Hill, B.G.6
  • 89
    • 34247161367 scopus 로고    scopus 로고
    • Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein
    • Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC, (2007). Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein. J Biol Chem 282: 5641-5652.
    • (2007) J Biol Chem , vol.282 , pp. 5641-5652
    • Sarkar, S.1    Davies, J.E.2    Huang, Z.3    Tunnacliffe, A.4    Rubinsztein, D.C.5
  • 90
    • 78650890352 scopus 로고    scopus 로고
    • Regulation of autophagy by ROS: Physiology and pathology
    • Scherz-Shouval R, Elazar Z, (2011). Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci 36: 30-38.
    • (2011) Trends Biochem Sci , vol.36 , pp. 30-38
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 91
    • 84871388330 scopus 로고    scopus 로고
    • Oxidative stress mediates chemerin-induced autophagy in endothelial cells
    • Shen W, Tian C, Chen H, Yang Y, Zhu D, Gao P, et al. (2013). Oxidative stress mediates chemerin-induced autophagy in endothelial cells. Free Radic Biol Med 55: 73-82.
    • (2013) Free Radic Biol Med , vol.55 , pp. 73-82
    • Shen, W.1    Tian, C.2    Chen, H.3    Yang, Y.4    Zhu, D.5    Gao, P.6
  • 92
    • 40849086607 scopus 로고    scopus 로고
    • Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis
    • Sluimer JC, Gasc JM, van Wanroij JL, Kisters N, Groeneweg M, Sollewijn Gelpke MD, et al. (2008). Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J Am Coll Cardiol 51: 1258-1265.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1258-1265
    • Sluimer, J.C.1    Gasc, J.M.2    Van Wanroij, J.L.3    Kisters, N.4    Groeneweg, M.5    Sollewijn Gelpke, M.D.6
  • 95
    • 84887489438 scopus 로고    scopus 로고
    • Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor
    • Torisu T, Torisu K, Lee IH, Liu J, Malide D, Combs CA, et al. (2013). Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor. Nat Med 19: 1281-1287.
    • (2013) Nat Med , vol.19 , pp. 1281-1287
    • Torisu, T.1    Torisu, K.2    Lee, I.H.3    Liu, J.4    Malide, D.5    Combs, C.A.6
  • 96
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • Tsukada M, Ohsumi Y, (1993). Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333: 169-174.
    • (1993) FEBS Lett , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 98
    • 84879495351 scopus 로고    scopus 로고
    • Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes
    • Wei YM, Li X, Xu M, Abais JM, Chen Y, Riebling CR, et al. (2013). Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. Cell Physiol Biochem 31: 925-937.
    • (2013) Cell Physiol Biochem , vol.31 , pp. 925-937
    • Wei, Y.M.1    Li, X.2    Xu, M.3    Abais, J.M.4    Chen, Y.5    Riebling, C.R.6
  • 99
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • Williams RS, Cheng L, Mudge AW, Harwood AJ, (2002). A common mechanism of action for three mood-stabilizing drugs. Nature 417: 292-295.
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 100
    • 77956813124 scopus 로고    scopus 로고
    • Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells
    • Xu K, Yang Y, Yan M, Zhan J, Fu X, Zheng X, (2010). Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells. J Lipid Res 51: 2581-2590.
    • (2010) J Lipid Res , vol.51 , pp. 2581-2590
    • Xu, K.1    Yang, Y.2    Yan, M.3    Zhan, J.4    Fu, X.5    Zheng, X.6
  • 101
    • 71649112895 scopus 로고    scopus 로고
    • 3D tomography reveals connections between the phagophore and endoplasmic reticulum
    • Yla-Anttila P, Vihinen H, Jokitalo E, Eskelinen EL, (2009a). 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 5: 1180-1185.
    • (2009) Autophagy , vol.5 , pp. 1180-1185
    • Yla-Anttila, P.1    Vihinen, H.2    Jokitalo, E.3    Eskelinen, E.L.4
  • 104
    • 84861983563 scopus 로고    scopus 로고
    • Autophagy activation: A novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway
    • Zhang Q, Yang YJ, Wang H, Dong QT, Wang TJ, Qian HY, et al. (2012). Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway. Stem Cells Dev 21: 1321-1332.
    • (2012) Stem Cells Dev , vol.21 , pp. 1321-1332
    • Zhang, Q.1    Yang, Y.J.2    Wang, H.3    Dong, Q.T.4    Wang, T.J.5    Qian, H.Y.6
  • 105
    • 77950188875 scopus 로고    scopus 로고
    • The autophagy-lysosome pathway: A novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells
    • Zhang YL, Cao YJ, Zhang X, Liu HH, Tong T, Xiao GD, et al. (2010). The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells. Biochem Biophys Res Commun 394: 377-382.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 377-382
    • Zhang, Y.L.1    Cao, Y.J.2    Zhang, X.3    Liu, H.H.4    Tong, T.5    Xiao, G.D.6
  • 106
    • 80054943500 scopus 로고    scopus 로고
    • Osteopontin stimulates autophagy via integrin/CD44 and p38 MAPK signaling pathways in vascular smooth muscle cells
    • Zheng YH, Tian C, Meng Y, Qin YW, Du YH, Du J, et al. (2012). Osteopontin stimulates autophagy via integrin/CD44 and p38 MAPK signaling pathways in vascular smooth muscle cells. J Cell Physiol 227: 127-135.
    • (2012) J Cell Physiol , vol.227 , pp. 127-135
    • Zheng, Y.H.1    Tian, C.2    Meng, Y.3    Qin, Y.W.4    Du, Y.H.5    Du, J.6
  • 107
    • 77955239270 scopus 로고    scopus 로고
    • Autophagosome formation depends on the small GTPase Rab1 and functional ER exit sites
    • Zoppino FC, Militello RD, Slavin I, Alvarez C, Colombo MI, (2010). Autophagosome formation depends on the small GTPase Rab1 and functional ER exit sites. Traffic 11: 1246-1261.
    • (2010) Traffic , vol.11 , pp. 1246-1261
    • Zoppino, F.C.1    Militello, R.D.2    Slavin, I.3    Alvarez, C.4    Colombo, M.I.5


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