Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques

Basic Research in Cardiology

Volumn 107, Issue 3, 2012, Pages

  De Meyer, Inge ^a   Martinet, Wim ^a   Schrijvers, Dorien M ^a   Timmermans, Jean Pierre ^a   Bult, Hidde ^a   De Meyer, Guido R Y ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Atherosclerosis; Autophagy; Inflammation; Macrophage; Toll like receptor 7

Indexed keywords

DEXAMETHASONE; IMIQUIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 7; VASCULAR CELL ADHESION MOLECULE 1; AMINOQUINOLINE DERIVATIVE; ANTIINFLAMMATORY AGENT; AUTACOID; CYTOKINE; MEMBRANE PROTEIN; TLR7 PROTEIN, HUMAN; TLR7 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTOPHAGOSOME; BIOACCUMULATION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; ENDOTHELIUM CELL; EXPERIMENTAL RABBIT; HEART CELL CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; LYMPHOCYTIC INFILTRATION; MACROAUTOPHAGY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER MEMBRANE; UPREGULATION; WESTERN BLOTTING; ANIMAL; AUTOPHAGY; C57BL MOUSE; CELL STRAIN U937; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; MOUSE MUTANT; NECROSIS; PATHOLOGY; RABBIT; TIME;

AMINOQUINOLINES; ANIMALS; ANTI-INFLAMMATORY AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CYTOKINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; NF-KAPPA B; PLAQUE, ATHEROSCLEROTIC; RABBITS; TIME FACTORS; TOLL-LIKE RECEPTOR 7; U937 CELLS;

EID: 84860153374     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-012-0269-1     Document Type: Article

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