Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes

Cellular Physiology and Biochemistry

Volumn 31, Issue 6, 2013, Pages 925-937

  Wei, Yu Miao ^a   Li, Xiang ^a   Xu, Ming ^a   Abais, Justine M ^a   Chen, Yang ^a   Riebling, Christopher R ^a   Boini, Krishna M ^a   Li, Pin Lan ^a   Zhang, Yang ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Autophagy; Coronary arterial myocyte; mTOR; Simvastatin

Indexed keywords

3 METHYLADENINE; BECLIN 1; CALPONIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDIC ACID; RAC1 PROTEIN; SIMVASTATIN; BIOLOGICAL MARKER; PROTEIN LC3B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; AUTOPHAGOSOME; AUTOPHAGY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORONARY ARTERIAL MYOCYTE; CORONARY ARTERY; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENE SILENCING; IN VIVO STUDY; LYSOSOME; MOUSE; MUSCLE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL TISSUE; ATG7 GENE; ATHEROGENESIS; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; GENE; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA;

EID: 84879495351     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000350111     Document Type: Article

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