IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes in gene expression and cytokine release in stimulated human monocytes

Innate Immunity

Volumn 21, Issue 4, 2015, Pages 429-449

  Gopinathan, Unni ^a,b   Brusletto, Berit Sletbakk ^a   Olstad, Ole Kristoffer ^a   Kierulf, Peter ^a,b   Berg, Jens Petter ^a,b   Brandtzaeg, Petter ^a,b   Øvstebø, Reidun ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

gene expression; inflammasomes; Interleukin 10; leukocyte immunoglobulin like receptor family; monocytes; Neisseria meningitidis; septic shock; systemic meningococcal disease; tissue factor; type I interferon signaling

Indexed keywords

CEFOTAXIME; CHLORAMPHENICOL; CREATININE; HEPARIN; IMMUNOGLOBULIN RECEPTOR; INFLAMMASOME; INFUSION FLUID; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NORADRENALIN; PENICILLIN G; TUMOR NECROSIS FACTOR ALPHA; TOLL LIKE RECEPTOR;

ADULT; ALKALOSIS; ANTIBIOTIC SENSITIVITY; ARTICLE; ARTIFICIAL VENTILATION; BACKACHE; BLOOD CLOTTING; BLOOD CLOTTING TEST; BLOOD CULTURE; CELL FUNCTION; CELL GROWTH; CELL INTERACTION; CELL MATURATION; CELL MOTION; CELL PROLIFERATION; CEREBROSPINAL FLUID; CHILD; CHILD HOSPITALIZATION; CLINICAL ARTICLE; CYTOKINE RELEASE; DIARRHEA; DISSEMINATED INTRAVASCULAR CLOTTING; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATIGUE; FEMALE; FEVER; FIBRINOLYSIS; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEADACHE; HOSPITAL ADMISSION; HUMAN; HUMAN CELL; INFANT; INTENSIVE CARE UNIT; MALE; MENINGOCOCCEMIA; METABOLIC ACIDOSIS; MONOCYTE; MULTIPLE ORGAN FAILURE; NEISSERIA MENINGITIDIS; NONHUMAN; PETECHIA; PH; PRESCHOOL CHILD; REHYDRATION; SEPTIC SHOCK; SIGNAL TRANSDUCTION; SORE THROAT; UPREGULATION; YOUNG ADULT; ADOLESCENT; ANTAGONISTS AND INHIBITORS; BLOOD; CASE REPORT; GENE EXPRESSION REGULATION; GENETICS; IMMUNITY; IMMUNOLOGY; MENINGOCOCCAL INFECTIONS; METABOLISM; MICROBIOLOGY; MONONUCLEAR CELL; SEPSIS;

NEISSERIA MENINGITIDIS;

ADOLESCENT; ADULT; BLOOD COAGULATION; CHILD; CHILD, PRESCHOOL; FEMALE; FIBRINOLYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY; INFANT; INFLAMMASOMES; INTERFERON TYPE I; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MENINGOCOCCAL INFECTIONS; NEISSERIA MENINGITIDIS; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; YOUNG ADULT;

EID: 84926487897     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425914547743     Document Type: Article

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