Computational studies of protein aggregation: Methods and applications

Annual Review of Physical Chemistry

Volumn 66, Issue , 2015, Pages 643-666

  Morriss Andrews, Alex ^a   Shea, Joan Emma ^a,b  

^a Department of Physics ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

amyloid fibrils; coarse grained models; enhanced sampling methods; molecular dynamics simulations; replica exchange molecular dynamics; systematic coarse graining

Indexed keywords

COARSE-GRAINED MODELING; COMPUTATIONAL CHEMISTRY; GLYCOPROTEINS; NEURODEGENERATIVE DISEASES; PROTEINS; SELF ASSEMBLY;

AMYLOID FIBRIL; COARSE GRAINING; COARSE-GRAINED MODELING; DYNAMICS SIMULATION; ENHANCED SAMPLING METHOD; ENHANCED SAMPLINGS; MOLECULAR DYNAMIC SIMULATION; REPLICA-EXCHANGE MOLECULAR DYNAMICS; SAMPLING METHOD; SYSTEMATIC COARSE GRAINING;

MOLECULAR DYNAMICS;

AMYLOID; PROTEIN AGGREGATE;

ALZHEIMER DISEASE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEINOSIS;

ALZHEIMER DISEASE; AMYLOID; ANIMALS; COMPUTER SIMULATION; HUMANS; MODELS, MOLECULAR; PROTEIN AGGREGATES; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN CONFORMATION;

EID: 84926483594     PISSN: 0066426X     EISSN: 15451593     Source Type: Book Series    
DOI: 10.1146/annurev-physchem-040513-103738     Document Type: Article

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