-
1
-
-
0347357617
-
Protein folding and misfolding
-
Dobson C.M. Protein folding and misfolding. Nature 426 (2003) 884-890
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
2
-
-
33750361540
-
A century-old debate on protein aggregation and neurodegeneration enters the clinic
-
Lansbury P.T., and Lashuel H.A. A century-old debate on protein aggregation and neurodegeneration enters the clinic. Nature 443 (2006) 774-779
-
(2006)
Nature
, vol.443
, pp. 774-779
-
-
Lansbury, P.T.1
Lashuel, H.A.2
-
3
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
-
Haass C., and Selkoe D.J. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide. Nature Rev. Mol. Cell Biol. 8 (2007) 101-112
-
(2007)
Nature Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
4
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
-
Caughey B., and Lansbury P.T. Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu. Rev. Neurosci. 26 (2003) 267-298
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury, P.T.2
-
5
-
-
17944368176
-
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation
-
Nilsberth C., Westlind-Danielsson A., Eckman C.B., Condron M.M., Axelman K., Forsell C., et al. The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation. Nature Neurosci. 4 (2001) 887-893
-
(2001)
Nature Neurosci.
, vol.4
, pp. 887-893
-
-
Nilsberth, C.1
Westlind-Danielsson, A.2
Eckman, C.B.3
Condron, M.M.4
Axelman, K.5
Forsell, C.6
-
6
-
-
9144272296
-
Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation
-
Cheng I.H., Palop J.J., Esposito L.A., Bien-Ly N., Yan F., and Mucke L. Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nature Med. 10 (2004) 1190-1192
-
(2004)
Nature Med.
, vol.10
, pp. 1190-1192
-
-
Cheng, I.H.1
Palop, J.J.2
Esposito, L.A.3
Bien-Ly, N.4
Yan, F.5
Mucke, L.6
-
7
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy
-
Conway K.A., Lee S.J., Rochet J.C., Ding T.T., Williamson R.E., and Lansbury P.T. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc. Natl Acad. Sci. USA 97 (2000) 571-576
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury, P.T.6
-
8
-
-
9044229145
-
On the nucleation and growth of amyloid β-protein fibrils: detection of nuclei and quantitation of rate constants
-
Lomakin A., Chung D.S., Benedek G.B., Kirschner D.A., and Teplow D.B. On the nucleation and growth of amyloid β-protein fibrils: detection of nuclei and quantitation of rate constants. Proc. Natl Acad. Sci. USA 93 (1996) 1125-1129
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 1125-1129
-
-
Lomakin, A.1
Chung, D.S.2
Benedek, G.B.3
Kirschner, D.A.4
Teplow, D.B.5
-
10
-
-
0032006678
-
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
-
Kelly J.W. The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways. Curr. Opin. Struct. Biol. 8 (1998) 101-106
-
(1998)
Curr. Opin. Struct. Biol.
, vol.8
, pp. 101-106
-
-
Kelly, J.W.1
-
11
-
-
23444445907
-
Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid
-
Gosal W.S., Morten I.J., Hewitt E.W., Smith D.A., Thomson N.H., and Radford S.E. Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid. J. Mol. Biol. 351 (2005) 850-864
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 850-864
-
-
Gosal, W.S.1
Morten, I.J.2
Hewitt, E.W.3
Smith, D.A.4
Thomson, N.H.5
Radford, S.E.6
-
12
-
-
33144467755
-
Amyloid formation under physiological conditions proceeds via a native-like folding intermediate
-
Jahn T.R., Parker M.J., Homans S.W., and Radford S. E. Amyloid formation under physiological conditions proceeds via a native-like folding intermediate. Nature Struct. Mol. Biol. 13 (2006) 195-201
-
(2006)
Nature Struct. Mol. Biol.
, vol.13
, pp. 195-201
-
-
Jahn, T.R.1
Parker, M.J.2
Homans, S.W.3
Radford, S. E.4
-
14
-
-
0035254995
-
Energy landscape theory for Alzheimer's amyloid β-peptide fibril elongation
-
Massi F., and Straub J.E. Energy landscape theory for Alzheimer's amyloid β-peptide fibril elongation. Proteins: Struct. Funct. Bioinformatics 42 (2001) 217-229
-
(2001)
Proteins: Struct. Funct. Bioinformatics
, vol.42
, pp. 217-229
-
-
Massi, F.1
Straub, J.E.2
-
15
-
-
0037255361
-
Assembly of amyloid protofibrils via critical oligomers-a novel pathway of amyloid formation
-
Modler A.J., Gast K., Lutsch G., and Damaschun G. Assembly of amyloid protofibrils via critical oligomers-a novel pathway of amyloid formation. J. Mol. Biol. 325 (2003) 135-148
-
(2003)
J. Mol. Biol.
, vol.325
, pp. 135-148
-
-
Modler, A.J.1
Gast, K.2
Lutsch, G.3
Damaschun, G.4
-
16
-
-
22044455269
-
A toy model for predicting the rate of amyloid formation from unfolded protein
-
Hall D., Hirota N., and Dobson C.M. A toy model for predicting the rate of amyloid formation from unfolded protein. J. Mol. Biol. 351 (2005) 195-205
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 195-205
-
-
Hall, D.1
Hirota, N.2
Dobson, C.M.3
-
17
-
-
23144459082
-
Molecular recycling within amyloid fibrils
-
Carulla N., Caddy G.L., Hall D.R., Zurdo J., Gairi M., Feliz M., et al. Molecular recycling within amyloid fibrils. Nature 436 (2005) 554-558
-
(2005)
Nature
, vol.436
, pp. 554-558
-
-
Carulla, N.1
Caddy, G.L.2
Hall, D.R.3
Zurdo, J.4
Gairi, M.5
Feliz, M.6
-
18
-
-
0032573090
-
Folding and aggregation of designed proteins
-
Broglia R.A., Tiana G., Pasquali S., Roman H.E., and Vigezzi E. Folding and aggregation of designed proteins. Proc. Natl Acad. Sci. USA 95 (1998) 12930-12933
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 12930-12933
-
-
Broglia, R.A.1
Tiana, G.2
Pasquali, S.3
Roman, H.E.4
Vigezzi, E.5
-
19
-
-
0031696773
-
Effect of denaturant and protein concentrations upon protein refolding and aggregation: a simple lattice model
-
Gupta P., Hall C.K., and Voegler A.C. Effect of denaturant and protein concentrations upon protein refolding and aggregation: a simple lattice model. Protein Sci. 7 (1998) 2642-2652
-
(1998)
Protein Sci.
, vol.7
, pp. 2642-2652
-
-
Gupta, P.1
Hall, C.K.2
Voegler, A.C.3
-
20
-
-
0033582587
-
Thermodynamics of model prions and its implications for the problem of prion protein folding
-
Harrison P.M., Chan H.S., Prusiner S.B., and Cohen F. E. Thermodynamics of model prions and its implications for the problem of prion protein folding. J. Mol. Biol. 286 (1999) 593-606
-
(1999)
J. Mol. Biol.
, vol.286
, pp. 593-606
-
-
Harrison, P.M.1
Chan, H.S.2
Prusiner, S.B.3
Cohen, F. E.4
-
21
-
-
0036228167
-
Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics
-
Dima R.I., and Thirumalai D. Exploring protein aggregation and self-propagation using lattice models: phase diagram and kinetics. Protein Sci. 11 (2002) 1036-1049
-
(2002)
Protein Sci.
, vol.11
, pp. 1036-1049
-
-
Dima, R.I.1
Thirumalai, D.2
-
22
-
-
10644278760
-
In silico study of amyloid β-protein folding and oligomerization
-
Urbanc B., Cruz L., Yun S., Buldyrev S.V., Bitan G., Teplow D.B., and Stanley H.E. In silico study of amyloid β-protein folding and oligomerization. Proc. Natl Acad. Sci. USA 101 (2004) 17345-17350
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 17345-17350
-
-
Urbanc, B.1
Cruz, L.2
Yun, S.3
Buldyrev, S.V.4
Bitan, G.5
Teplow, D.B.6
Stanley, H.E.7
-
23
-
-
9244260521
-
Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides
-
Nguyen H.D., and Hall C.K. Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides. Proc. Natl Acad. Sci. USA 101 (2004) 16180-16185
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 16180-16185
-
-
Nguyen, H.D.1
Hall, C.K.2
-
24
-
-
0346688724
-
Assembly and kinetic folding pathways of a tetrameric beta-sheet complex: molecular dynamics simulations on simplified off-lattice protein models
-
Jang H., Hall C.K., and Zhou Y. Assembly and kinetic folding pathways of a tetrameric beta-sheet complex: molecular dynamics simulations on simplified off-lattice protein models. Biophys. J. 86 (2004) 31-49
-
(2004)
Biophys. J.
, vol.86
, pp. 31-49
-
-
Jang, H.1
Hall, C.K.2
Zhou, Y.3
-
25
-
-
55449095000
-
Molecular origin of polyglutamine aggregation in neurodegenerative diseases
-
Khare S.D., Ding F., Gwanmesia K.N., and Dokholyan N.V. Molecular origin of polyglutamine aggregation in neurodegenerative diseases. PLoS Comput. Biol. 1 (2005) 230-235
-
(2005)
PLoS Comput. Biol.
, vol.1
, pp. 230-235
-
-
Khare, S.D.1
Ding, F.2
Gwanmesia, K.N.3
Dokholyan, N.V.4
-
26
-
-
27644528932
-
A single disulfide bond differentiates aggregation pathways of beta2-microglobulin
-
Chen Y., and Dokholyan N.V. A single disulfide bond differentiates aggregation pathways of beta2-microglobulin. J. Mol. Biol. 354 (2005) 473-482
-
(2005)
J. Mol. Biol.
, vol.354
, pp. 473-482
-
-
Chen, Y.1
Dokholyan, N.V.2
-
27
-
-
20344391939
-
Theoretical model of prion propagation: a misfolded protein induces misfolding
-
Malolepsza E., Boniecki M., Kolinski A., and Piela L. Theoretical model of prion propagation: a misfolded protein induces misfolding. Proc. Natl Acad. Sci. USA 102 (2005) 7835-7840
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 7835-7840
-
-
Malolepsza, E.1
Boniecki, M.2
Kolinski, A.3
Piela, L.4
-
28
-
-
34547251863
-
Self-assembly of beta-sheet forming peptides into chiral fibrillar clusters
-
Bellesia G., and Shea J.-E. Self-assembly of beta-sheet forming peptides into chiral fibrillar clusters. J. Chem. Phys. 126 (2007) 245104
-
(2007)
J. Chem. Phys.
, vol.126
, pp. 245104
-
-
Bellesia, G.1
Shea, J.-E.2
-
29
-
-
23444447864
-
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates
-
Plakoutsi G., Bemporad F., Calamai M., Taddei N., Dobson C.M., and Chiti F. Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates. J. Mol. Biol. 351 (2005) 910-922
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 910-922
-
-
Plakoutsi, G.1
Bemporad, F.2
Calamai, M.3
Taddei, N.4
Dobson, C.M.5
Chiti, F.6
-
31
-
-
0037627715
-
The role of side-chain interactions in the early steps of aggregation: molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35
-
Gsponer J., Haberthür U., and Caflisch A. The role of side-chain interactions in the early steps of aggregation: molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35. Proc. Natl Acad. Sci. USA 100 (2003) 5154-5159
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 5154-5159
-
-
Gsponer, J.1
Haberthür, U.2
Caflisch, A.3
-
32
-
-
0037337271
-
16-22 amyloid peptides into antiparallel β sheets
-
16-22 amyloid peptides into antiparallel β sheets. Structure 11 (2003) 295-307
-
(2003)
Structure
, vol.11
, pp. 295-307
-
-
Klimov, D.1
Thirumalai, D.2
-
33
-
-
10044289451
-
Sampling the self-assembly pathways of KFFE hexamers
-
Wei G., Mousseau N., and Derreumaux P. Sampling the self-assembly pathways of KFFE hexamers. Biophys. J. 87 (2004) 3648-3656
-
(2004)
Biophys. J.
, vol.87
, pp. 3648-3656
-
-
Wei, G.1
Mousseau, N.2
Derreumaux, P.3
-
34
-
-
4444346811
-
Kinetic control of dimer structure formation in amyloid fibrillogenesis
-
Hwang W., Zhang S., Kamm R.D., and Karplus M. Kinetic control of dimer structure formation in amyloid fibrillogenesis. Proc. Natl Acad. Sci. USA 101 (2004) 12916-12921
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 12916-12921
-
-
Hwang, W.1
Zhang, S.2
Kamm, R.D.3
Karplus, M.4
-
35
-
-
26844435756
-
Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments
-
Buchete N.-V., Tycko R., and Hummer G. Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments. J. Mol. Biol. 353 (2005) 804-821
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 804-821
-
-
Buchete, N.-V.1
Tycko, R.2
Hummer, G.3
-
36
-
-
19544375553
-
Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations
-
Lopez de la Paz M., de Mori G.M.S., Serrano L., and Colombo G. Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations. J. Mol. Biol. 349 (2005) 583-596
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 583-596
-
-
Lopez de la Paz, M.1
de Mori, G.M.S.2
Serrano, L.3
Colombo, G.4
-
37
-
-
33745727173
-
Interpreting the aggregation kinetics of amyloid peptides
-
Pellarin R., and Caflisch A. Interpreting the aggregation kinetics of amyloid peptides. J. Mol. Biol. 360 (2006) 882-892
-
(2006)
J. Mol. Biol.
, vol.360
, pp. 882-892
-
-
Pellarin, R.1
Caflisch, A.2
-
38
-
-
33846160381
-
Polymorphism in the intermediates and products of amyloid assembly
-
Kodali R., and Wetzel R. Polymorphism in the intermediates and products of amyloid assembly. Curr. Opin. Struct. Biol. 17 (2007) 48-57
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 48-57
-
-
Kodali, R.1
Wetzel, R.2
-
39
-
-
34547156274
-
Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins
-
Murphy R.M. Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins. Biochim. Biophys. Acta 1768 (2007) 1923-1934
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 1923-1934
-
-
Murphy, R.M.1
-
40
-
-
4143090730
-
The protein folding network
-
Rao F., and Caflisch A. The protein folding network. J. Mol. Biol. 342 (2004) 299-306
-
(2004)
J. Mol. Biol.
, vol.342
, pp. 299-306
-
-
Rao, F.1
Caflisch, A.2
-
41
-
-
32344450229
-
Network and graph analyses of folding free energy surfaces
-
Caflisch A. Network and graph analyses of folding free energy surfaces. Curr. Opin. Struct. Biol. 16 (2006) 71-78
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 71-78
-
-
Caflisch, A.1
-
42
-
-
0034733023
-
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism
-
Esler W.P., Stimson E.R., Jennings J.M., Vinters H. V., Ghilardi J.R., Lee J.P., et al. Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism. Biochemistry 39 (2000) 6288-6295
-
(2000)
Biochemistry
, vol.39
, pp. 6288-6295
-
-
Esler, W.P.1
Stimson, E.R.2
Jennings, J.M.3
Vinters, H. V.4
Ghilardi, J.R.5
Lee, J.P.6
-
43
-
-
33644854942
-
Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the "dock-and-lock" model
-
Gobbi M., Colombo L., Morbin M., Mazzoleni G., Accardo E., Vanoni M., et al. Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the "dock-and-lock" model. J. Biol. Chem. 281 (2006) 843-849
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 843-849
-
-
Gobbi, M.1
Colombo, L.2
Morbin, M.3
Mazzoleni, G.4
Accardo, E.5
Vanoni, M.6
-
44
-
-
33846036362
-
Monomer adds to preformed structured oligomers of abeta-peptides by a two-stage dock-lock mechanism
-
Nguyen P.H., Li M.S., Stock G., Straub J.E., and Thirumalai D. Monomer adds to preformed structured oligomers of abeta-peptides by a two-stage dock-lock mechanism. Proc. Natl Acad. Sci. USA 104 (2007) 111-116
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 111-116
-
-
Nguyen, P.H.1
Li, M.S.2
Stock, G.3
Straub, J.E.4
Thirumalai, D.5
-
45
-
-
17144426174
-
Amyloidogenic self-assembly of insulin aggregates probed by high resolution atomic force microscopy
-
Jansen R., Dzwolak W., and Winter R. Amyloidogenic self-assembly of insulin aggregates probed by high resolution atomic force microscopy. Biophys. J. 88 (2005) 1344-1353
-
(2005)
Biophys. J.
, vol.88
, pp. 1344-1353
-
-
Jansen, R.1
Dzwolak, W.2
Winter, R.3
-
46
-
-
0033520461
-
Amyloid β-protein fibrillogenesis. structure and biological activity of protofibrillar intermediates
-
Walsh D., Hartley D.M., Kusumoto Y., Fezoui Y., Condron M., Lomakin A., et al. Amyloid β-protein fibrillogenesis. structure and biological activity of protofibrillar intermediates. J. Biol. Chem. 274 (1999) 25945-25952
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25945-25952
-
-
Walsh, D.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.5
Lomakin, A.6
-
48
-
-
3042584515
-
The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
-
Tartaglia G.G., Cavalli A., Pellarin R., and Caflisch A. The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates. Protein Sci. 13 (2004) 1939-1941
-
(2004)
Protein Sci.
, vol.13
, pp. 1939-1941
-
-
Tartaglia, G.G.1
Cavalli, A.2
Pellarin, R.3
Caflisch, A.4
|