A multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide gnnqqny from the yeast prion sup-35

PLoS Computational Biology

Volumn 7, Issue 5, 2011, Pages

  Nasica Labouze, Jessica ^a   Meli, Massimiliano ^b   Derreumaux, Philippe ^c   Colombo, Giorgio ^b   Mousseau, Normand ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CNR   (Italy)

^c France   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMS; GLYCOPROTEINS; MOLECULAR DYNAMICS; OLIGOMERS;

AGGREGATION PROCESS; ATOMIC-RESOLUTION; COARSE-GRAINED POTENTIAL; DEGENERATIVE DISEASE; MULTI-SCALE APPROACHES; REPLICA-EXCHANGE MOLECULAR DYNAMICS SIMULATIONS; SAMPLING PROPERTIES; SELF ORGANIZATIONS; YEAST PRIONS;

PEPTIDES;

AMYLOID PROTEIN; GLYCYLASPARAGINYLASPARAGINYLGLUTAMINYLGLUTAMINYLASPARAGINYLTYROSINE; PEPTIDE; UNCLASSIFIED DRUG; AMYLOID; OLIGOPEPTIDE; SACCHAROMYCES CEREVISIAE PROTEIN; SUP35 PROTEIN, S CEREVISIAE; TRANSLATION TERMINATION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR DYNAMICS; OLIGOMERIZATION; PEPTIDE ANALYSIS; PROTEIN AGGREGATION; PROTEIN POLYMERIZATION; STRUCTURE ANALYSIS; THERMOSTABILITY; CHEMISTRY; PRION; PROTEIN CONFORMATION;

AMYLOID; MOLECULAR DYNAMICS SIMULATION; OLIGOPEPTIDES; PEPTIDE TERMINATION FACTORS; PRIONS; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 79958122197     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002051     Document Type: Article

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