-
1
-
-
80755186529
-
Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6
-
Ahn, V.E., Chu, M.L., Choi, H.J. et al. (2011) Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6. Developmental Cell, 21, 862-873.
-
(2011)
Developmental Cell
, vol.21
, pp. 862-873
-
-
Ahn, V.E.1
Chu, M.L.2
Choi, H.J.3
-
2
-
-
84863164982
-
Biglycan is an extracellular MuSK binding protein important for synapse stability
-
Amenta, A.R., Creely, H.E., Mercado, M.L. et al. (2012) Biglycan is an extracellular MuSK binding protein important for synapse stability. The Journal of Neuroscience, 32, 2324-2334.
-
(2012)
The Journal of Neuroscience
, vol.32
, pp. 2324-2334
-
-
Amenta, A.R.1
Creely, H.E.2
Mercado, M.L.3
-
3
-
-
0347916881
-
Comparative genomic analysis of the eightmembered ring cystine knot-containing bone morphogenetic protein antagonists
-
Avsian-Kretchmer, O. and Hsueh, A.J.W. (2004) Comparative genomic analysis of the eightmembered ring cystine knot-containing bone morphogenetic protein antagonists. Molecular Endocrinology, 18, 1-12.
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 1-12
-
-
Avsian-Kretchmer, O.1
Hsueh, A.J.W.2
-
4
-
-
0033523005
-
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
-
Bafico, A., Gazit, A., Pramila, T. et al. (1999) Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. The Journal of Biological Chemistry, 274, 16180-16187.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 16180-16187
-
-
Bafico, A.1
Gazit, A.2
Pramila, T.3
-
5
-
-
0037519264
-
The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases
-
Bányai, L. and Patthy, L. (1999) The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases. Protein Science, 8, 1636-1642.
-
(1999)
Protein Science
, vol.8
, pp. 1636-1642
-
-
Bányai, L.1
Patthy, L.2
-
6
-
-
80052638746
-
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling
-
Berndt, J.D., Aoyagi, A., Yang, P. et al. (2011) Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling. The Journal of Cell Biology, 194, 737-750.
-
(2011)
The Journal of Cell Biology
, vol.194
, pp. 737-750
-
-
Berndt, J.D.1
Aoyagi, A.2
Yang, P.3
-
7
-
-
0029994517
-
A new member of the frizzled family from Drosophila functions as a Wingless receptor
-
Bhanot, P., Brink, M., Samos, C.H. et al. (1996) A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature, 382, 225-230.
-
(1996)
Nature
, vol.382
, pp. 225-230
-
-
Bhanot, P.1
Brink, M.2
Samos, C.H.3
-
8
-
-
36849048683
-
Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function
-
Bhat, R.A., Stauffer, B., Komm, B.S., and Bodine, P.V.N. (2007) Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function. Journal of Cellular Biochemistry, 102, 1519-1528.
-
(2007)
Journal of Cellular Biochemistry
, vol.102
, pp. 1519-1528
-
-
Bhat, R.A.1
Stauffer, B.2
Komm, B.S.3
Bodine, P.V.N.4
-
9
-
-
34250827150
-
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
-
Bilic, J., Huang, Y-L., Davidson, G. et al. (2007) Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science, 316, 1619-1622.
-
(2007)
Science
, vol.316
, pp. 1619-1622
-
-
Bilic, J.1
Huang, Y.-L.2
Davidson, G.3
-
10
-
-
77950592184
-
Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6
-
Bourhis, E., Tam, C., Franke, Y. et al. (2010) Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. The Journal of Biological Chemistry, 285, 9172-9179.
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 9172-9179
-
-
Bourhis, E.1
Tam, C.2
Franke, Y.3
-
11
-
-
0032581370
-
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family
-
Brown, S.D., Twells, R.C., Hey, P.J. et al. (1998) Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. Biochemical and Biophysical Research Communications, 248, 879-888.
-
(1998)
Biochemical and Biophysical Research Communications
, vol.248
, pp. 879-888
-
-
Brown, S.D.1
Twells, R.C.2
Hey, P.J.3
-
12
-
-
78751692388
-
Mitogenactivated protein kinases promote WNT/β-catenin signaling via phosphorylation of LRP6
-
Cervenka, I., Wolf, J., Mašek, J. et al. (2010) Mitogenactivated protein kinases promote WNT/β-catenin signaling via phosphorylation of LRP6. Molecular and Cellular Biology, 31, 179-189.
-
(2010)
Molecular and Cellular Biology
, vol.31
, pp. 179-189
-
-
Cervenka, I.1
Wolf, J.2
Mašek, J.3
-
13
-
-
0041470133
-
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
-
Chen, W., ten Berge, D., Brown, J. et al. (2003) Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science, 301, 1391-1394.
-
(2003)
Science
, vol.301
, pp. 1391-1394
-
-
Chen, W.1
ten Berge, D.2
Brown, J.3
-
14
-
-
71749094586
-
G proteincoupled receptor kinases phosphorylate LRP6 in the Wnt pathway
-
Chen, M., Philipp, M., Wang, J. et al. (2009) G proteincoupled receptor kinases phosphorylate LRP6 in the Wnt pathway. The Journal of Biological Chemistry, 284, 35040-35048.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 35040-35048
-
-
Chen, M.1
Philipp, M.2
Wang, J.3
-
15
-
-
79952470911
-
Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6
-
Chen, J., Liu, CC., Li, Q. et al. (2011) Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6. Structure, 19, 313-323.
-
(2011)
Structure
, vol.19
, pp. 313-323
-
-
Chen, J.1
Liu, C.C.2
Li, Q.3
-
17
-
-
8444223093
-
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
-
Cong, F., Schweizer, L., and Varmus, H. (2004) Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development, 131, 5103-5115.
-
(2004)
Development
, vol.131
, pp. 5103-5115
-
-
Cong, F.1
Schweizer, L.2
Varmus, H.3
-
19
-
-
45849104800
-
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin
-
Cselenyi, C.S., Jernigan, K.K., Tahinci, E. et al. (2008) LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin. Proceedings of the National Academy of Sciences of the United States of America, 105, 8032-8037.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 8032-8037
-
-
Cselenyi, C.S.1
Jernigan, K.K.2
Tahinci, E.3
-
20
-
-
0037423256
-
Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila
-
Culi, J. and Mann, R.S. (2003) Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell, 112, 343-354.
-
(2003)
Cell
, vol.112
, pp. 343-354
-
-
Culi, J.1
Mann, R.S.2
-
21
-
-
0035811492
-
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
-
Dann, C.E., Hsieh, J.C., Rattner, A. et al. (2001) Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature, 412, 86-90.
-
(2001)
Nature
, vol.412
, pp. 86-90
-
-
Dann, C.E.1
Hsieh, J.C.2
Rattner, A.3
-
22
-
-
77955317205
-
Emerging links between CDK cell cycle regulators and Wnt signaling
-
Davidson, G. and Niehrs, C. (2010) Emerging links between CDK cell cycle regulators and Wnt signaling. Trends in Cell Biology, 20, 453-460.
-
(2010)
Trends in Cell Biology
, vol.20
, pp. 453-460
-
-
Davidson, G.1
Niehrs, C.2
-
23
-
-
28644444440
-
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson, G., Wu, W., Shen, J. et al. (2005) Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature, 438, 867-872.
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
Wu, W.2
Shen, J.3
-
24
-
-
71649108294
-
Cell cycle control of wnt receptor activation
-
Davidson, G., Shen, J., Huang, Y.L. et al. (2009) Cell cycle control of wnt receptor activation. Developmental Cell, 17, 788-799.
-
(2009)
Developmental Cell
, vol.17
, pp. 788-799
-
-
Davidson, G.1
Shen, J.2
Huang, Y.L.3
-
25
-
-
79960361661
-
Coordinated action of CK1 isoforms in canonical Wnt signaling
-
del Valle-Perez, B., Arques, O., Vinyoles, M. et al. (2011) Coordinated action of CK1 isoforms in canonical Wnt signaling. Molecular and Cellular Biology, 31, 2877-2888.
-
(2011)
Molecular and Cellular Biology
, vol.31
, pp. 2877-2888
-
-
del Valle-Perez, B.1
Arques, O.2
Vinyoles, M.3
-
26
-
-
0033545936
-
Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein- coupled receptor kinases
-
Dicker, F., Quitterer, U., Winstel, R. et al. (1999) Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein- coupled receptor kinases. Proceedings of the National Academy of Sciences of the United States of America, 96, 5476-5481.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 5476-5481
-
-
Dicker, F.1
Quitterer, U.2
Winstel, R.3
-
27
-
-
19344363080
-
The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye
-
Djiane, A., Yogev, S., and Mlodzik, M. (2005) The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell, 121, 621-631.
-
(2005)
Cell
, vol.121
, pp. 621-631
-
-
Djiane, A.1
Yogev, S.2
Mlodzik, M.3
-
28
-
-
33846449190
-
Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
-
Ellies, D.L. Viviano, B., McCarthy, J. et al. (2006) Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. Journal of Bone and Mineral Research, 21, 1738-1749.
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, pp. 1738-1749
-
-
Ellies, D.L.1
Viviano, B.2
McCarthy, J.3
-
29
-
-
79952148045
-
Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin
-
Fiedler, M., Mendoza-Topaz, C., Rutherford, T.J. et al. (2011) Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin. Proceedings of the National Academy of Sciences of the United States of America, 108, 1937-1942.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 1937-1942
-
-
Fiedler, M.1
Mendoza-Topaz, C.2
Rutherford, T.J.3
-
30
-
-
84861970846
-
A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway
-
Flowers, G.P., Topczewska, J.M., and Topczewski, J. (2012) A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway. Development, 139, 2416-2425.
-
(2012)
Development
, vol.139
, pp. 2416-2425
-
-
Flowers, G.P.1
Topczewska, J.M.2
Topczewski, J.3
-
31
-
-
73949092833
-
A study on the interactions between heparan sulfate proteoglycans and Wnt proteins
-
Fuerer, C., Habib, S.J., and Nusse, R. (2010) A study on the interactions between heparan sulfate proteoglycans and Wnt proteins. Developmental Dynamics, 239, 184-190.
-
(2010)
Developmental Dynamics
, vol.239
, pp. 184-190
-
-
Fuerer, C.1
Habib, S.J.2
Nusse, R.3
-
32
-
-
0037422571
-
Lowdensity lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
-
Fujino, T., Hiroshi, A., Man-Jong, K. et al. (2003) Lowdensity lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proceedings of the National Academy of Sciences of the United States of America, 100, 229-234.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 229-234
-
-
Fujino, T.1
Hiroshi, A.2
Man-Jong, K.3
-
33
-
-
34249893122
-
Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings
-
Furushima, K., Yamamoto, A., Nagano, T. et al. (2007) Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Developmental Biology, 306, 480-492.
-
(2007)
Developmental Biology
, vol.306
, pp. 480-492
-
-
Furushima, K.1
Yamamoto, A.2
Nagano, T.3
-
34
-
-
0036111641
-
HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient
-
Giráldez, A.J., Copley, R.R., and Cohen, S.M. (2002) HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Developmental Cell, 2, 667-676.
-
(2002)
Developmental Cell
, vol.2
, pp. 667-676
-
-
Giráldez, A.J.1
Copley, R.R.2
Cohen, S.M.3
-
35
-
-
0032556910
-
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
-
Glinka, A., Wu, W., Delius, H. et al. (1998) Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature, 391, 357-362.
-
(1998)
Nature
, vol.391
, pp. 357-362
-
-
Glinka, A.1
Wu, W.2
Delius, H.3
-
36
-
-
84856722605
-
Initiation of synapse formation by Wnt-induced MuSK endocytosis
-
Gordon, L.R., Gribble, K.D., Syrett, C.M., and Granato, M. (2012) Initiation of synapse formation by Wnt-induced MuSK endocytosis. Development, 139, 1023-1033.
-
(2012)
Development
, vol.139
, pp. 1023-1033
-
-
Gordon, L.R.1
Gribble, K.D.2
Syrett, C.M.3
Granato, M.4
-
38
-
-
34748880246
-
Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6
-
Guidato, S. and Itasaki, N. (2007) Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6. Developmental Biology, 310, 250-263.
-
(2007)
Developmental Biology
, vol.310
, pp. 250-263
-
-
Guidato, S.1
Itasaki, N.2
-
39
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund, K. and Dikic, I. (2005) Ubiquitylation and cell signaling. The EMBO Journal, 24, 3353-3359.
-
(2005)
The EMBO Journal
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
40
-
-
84860765166
-
ZNRF3 promotes Wnt receptor turnover in an R-spondinsensitive manner
-
Hao, H-X., Xie, Y., Zhang, Y. et al. (2012) ZNRF3 promotes Wnt receptor turnover in an R-spondinsensitive manner. Nature, 485, 195-200.
-
(2012)
Nature
, vol.485
, pp. 195-200
-
-
Hao, H.-X.1
Xie, Y.2
Zhang, Y.3
-
41
-
-
38349026604
-
Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling
-
Hassler, C., Cruciat, C.M., Huang, Y.L. et al. (2007) Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. Development, 134, 4255-4263.
-
(2007)
Development
, vol.134
, pp. 4255-4263
-
-
Hassler, C.1
Cruciat, C.M.2
Huang, Y.L.3
-
42
-
-
4544377878
-
Wnt signaling went derailed again: a new track via the LIN-18 receptor?
-
He, X. (2004) Wnt signaling went derailed again: a new track via the LIN-18 receptor? Cell, 118, 668-670.
-
(2004)
Cell
, vol.118
, pp. 668-670
-
-
He, X.1
-
43
-
-
12944321364
-
Antagonizing Wnt and FGF receptors: an enemy from within (the ER)
-
He, X. (2005) Antagonizing Wnt and FGF receptors: an enemy from within (the ER). Cell, 120, 156-158.
-
(2005)
Cell
, vol.120
, pp. 156-158
-
-
He, X.1
-
44
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/betacatenin signaling: arrows point the way
-
He, X., Semenov, M., Tamai, K., and Zeng, X. (2004) LDL receptor-related proteins 5 and 6 in Wnt/betacatenin signaling: arrows point the way. Development, 131, 1663-1677.
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
45
-
-
84856393994
-
Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8
-
Hendaoui, I., Lavergne, E., Lee, H.S. et al. (2012) Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8. PLoS One, 7, e30601.
-
(2012)
PLoS One
, vol.7
, pp. e30601
-
-
Hendaoui, I.1
Lavergne, E.2
Lee, H.S.3
-
46
-
-
84858228855
-
Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis
-
Ho, H-Y.H., Susman, M.W., Bikoff, J.B. et al. (2012) Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis. Proceedings of the National Academy of Sciences of the United States of America, 109, 4044-4051.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 4044-4051
-
-
Ho, H.-Y.H.1
Susman, M.W.2
Bikoff, J.B.3
-
47
-
-
0037423222
-
Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity
-
Hsieh, J-C., Lee, L., Zhang, L. et al. (2003) Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell, 112, 355-367.
-
(2003)
Cell
, vol.112
, pp. 355-367
-
-
Hsieh, J.-C.1
Lee, L.2
Zhang, L.3
-
48
-
-
4544329969
-
C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling
-
Inoue, T., Oz, H.S., Wiland, D. et al. (2004) C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling. Cell, 118, 795-806.
-
(2004)
Cell
, vol.118
, pp. 795-806
-
-
Inoue, T.1
Oz, H.S.2
Wiland, D.3
-
49
-
-
0141725483
-
Wise, a context-dependent activator and inhibitor of Wnt signalling
-
Itasaki, N., Jones, C.M., Mercurio, S. et al. (2003) Wise, a context-dependent activator and inhibitor of Wnt signalling. Development, 130, 4295-4305.
-
(2003)
Development
, vol.130
, pp. 4295-4305
-
-
Itasaki, N.1
Jones, C.M.2
Mercurio, S.3
-
50
-
-
84863543371
-
Structural basis of Wnt recognition by Frizzled
-
Janda, C.Y., Waghray, D., Levin, A.M. et al. (2012) Structural basis of Wnt recognition by Frizzled. Science, 337, 59-64.
-
(2012)
Science
, vol.337
, pp. 59-64
-
-
Janda, C.Y.1
Waghray, D.2
Levin, A.M.3
-
51
-
-
11144237279
-
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I
-
Jia, J., Tong, C., Wang, B. et al. (2004) Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature, 432, 1045-1050.
-
(2004)
Nature
, vol.432
, pp. 1045-1050
-
-
Jia, J.1
Tong, C.2
Wang, B.3
-
52
-
-
61549135797
-
Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor
-
Jing, L., Lefebvre, J.L., Gordon, L.R., and Granato, M. (2009) Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor. Neuron, 61, 721-733.
-
(2009)
Neuron
, vol.61
, pp. 721-733
-
-
Jing, L.1
Lefebvre, J.L.2
Gordon, L.R.3
Granato, M.4
-
53
-
-
27944471018
-
Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice
-
Johnson, E.B., Hammer, R.E., and Herz, J. (2005) Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Human Molecular Genetics, 14, 3523-3538.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 3523-3538
-
-
Johnson, E.B.1
Hammer, R.E.2
Herz, J.3
-
54
-
-
13844269808
-
LRP5 and Wnt signaling: a union made for bone
-
Johnson, M.L., Harnish, K., Nusse, R., and Van Hul, W. (2004) LRP5 and Wnt signaling: a union made for bone. Journal of Bone and Mineral Research, 19, 1749-1757.
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, pp. 1749-1757
-
-
Johnson, M.L.1
Harnish, K.2
Nusse, R.3
Van Hul, W.4
-
55
-
-
83555162471
-
Waif1/5 T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization
-
Kagermeier-Schenk, B., Wehner, D., Ozhan-Kizil, G. et al. (2011) Waif1/5 T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization. Developmental Cell, 21, 1129-1143.
-
(2011)
Developmental Cell
, vol.21
, pp. 1129-1143
-
-
Kagermeier-Schenk, B.1
Wehner, D.2
Ozhan-Kizil, G.3
-
56
-
-
0037092049
-
Cbfa1- independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
-
Kato, M., Patel, M.S., Levasseur, R. et al. (2002) Cbfa1- independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. The Journal of Cell Biology, 157, 303-314.
-
(2002)
The Journal of Cell Biology
, vol.157
, pp. 303-314
-
-
Kato, M.1
Patel, M.S.2
Levasseur, R.3
-
57
-
-
2342441840
-
The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice
-
Kelly, O.G., Pinson, K.I., and Skarnes, W.C. (2004) The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development, 131, 2803-2815.
-
(2004)
Development
, vol.131
, pp. 2803-2815
-
-
Kelly, O.G.1
Pinson, K.I.2
Skarnes, W.C.3
-
58
-
-
80054777961
-
New insights into the mechanism of Wnt signaling pathway activation
-
Kikuchi, A., Yamamoto, H., Sato, A., and Matsumoto, S. (2011) New insights into the mechanism of Wnt signaling pathway activation. International Review of Cell and Molecular Biology, 291, 21-71.
-
(2011)
International Review of Cell and Molecular Biology
, vol.291
, pp. 21-71
-
-
Kikuchi, A.1
Yamamoto, H.2
Sato, A.3
Matsumoto, S.4
-
59
-
-
72749084368
-
Mouse models of altered protein kinase A signaling
-
Kirschner, L.S., Yin, Z., Jones, G.N., and Mahoney, E. (2009) Mouse models of altered protein kinase A signaling. Endocrine-Related Cancer, 16, 773-793.
-
(2009)
Endocrine-Related Cancer
, vol.16
, pp. 773-793
-
-
Kirschner, L.S.1
Yin, Z.2
Jones, G.N.3
Mahoney, E.4
-
60
-
-
84865517676
-
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
-
Koo, B-K., Spit, M., Jordens, I. et al. (2012) Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature, 488, 665-669.
-
(2012)
Nature
, vol.488
, pp. 665-669
-
-
Koo, B.-K.1
Spit, M.2
Jordens, I.3
-
61
-
-
80054685356
-
Yellow submarine of the Wnt/ Frizzled signaling: submerging from the G protein harbor to the targets
-
Koval, A., Purvanov, V., Egger-Adam, D., and Katanaev, V.L. (2011) Yellow submarine of the Wnt/ Frizzled signaling: submerging from the G protein harbor to the targets. Biochemical Pharmacology, 82, 1311-1319.
-
(2011)
Biochemical Pharmacology
, vol.82
, pp. 1311-1319
-
-
Koval, A.1
Purvanov, V.2
Egger-Adam, D.3
Katanaev, V.L.4
-
62
-
-
0030933978
-
Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
-
Leyns, L., Bouwmeester, T., Kim, S.H. et al. (1997) Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell, 88, 747-756.
-
(1997)
Cell
, vol.88
, pp. 747-756
-
-
Leyns, L.1
Bouwmeester, T.2
Kim, S.H.3
-
63
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
Li, X., Zhang, Y., Kang, H. et al. (2005) Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. The Journal of Biological Chemistry, 280, 19883-19887.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
-
64
-
-
79959467696
-
Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation
-
Liang, J., Fu, Y., Cruciat, C.M. et al. (2011) Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Molecular and Cellular Biology, 31, 2577-2590.
-
(2011)
Molecular and Cellular Biology
, vol.31
, pp. 2577-2590
-
-
Liang, J.1
Fu, Y.2
Cruciat, C.M.3
-
65
-
-
0030799081
-
The cysteine- rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling
-
Lin, K., Wang, S., Julius, M.A. et al. (1997) The cysteine- rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America, 94, 11196-11200.
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, pp. 11196-11200
-
-
Lin, K.1
Wang, S.2
Julius, M.A.3
-
66
-
-
69249112245
-
Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals
-
Lintern, K.B., Guidato, S., Rowe, A. et al. (2009) Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals. The Journal of Biological Chemistry, 284, 23159-23168.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 23159-23168
-
-
Lintern, K.B.1
Guidato, S.2
Rowe, A.3
-
67
-
-
0042131956
-
A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
-
Liu, G., Bafico, A., Harris, V.K., and Aaronson, S.A. (2003) A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Molecular Cell Biology, 23, 5825-5835.
-
(2003)
Molecular Cell Biology
, vol.23
, pp. 5825-5835
-
-
Liu, G.1
Bafico, A.2
Harris, V.K.3
Aaronson, S.A.4
-
68
-
-
5344273899
-
Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth
-
Lu, W., Yamamoto, V., Ortega, B., and Baltimore, D. (2004) Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell, 119, 97-108.
-
(2004)
Cell
, vol.119
, pp. 97-108
-
-
Lu, W.1
Yamamoto, V.2
Ortega, B.3
Baltimore, D.4
-
69
-
-
55349114398
-
Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis
-
Lyu, J., Yamamoto, V., and Lu, W. (2008) Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis. Developmental Cell, 15, 773-780.
-
(2008)
Developmental Cell
, vol.15
, pp. 773-780
-
-
Lyu, J.1
Yamamoto, V.2
Lu, W.3
-
70
-
-
84867071759
-
A finger on the pulse of Wnt receptor signaling
-
MacDonald, B.T. and He, X. (2012) A finger on the pulse of Wnt receptor signaling. Cell Research, 22, 1410-1412.
-
(2012)
Cell Research
, vol.22
, pp. 1410-1412
-
-
MacDonald, B.T.1
He, X.2
-
71
-
-
47049121052
-
Wnt signal amplification: activity, cooperativity and regulation of multiple intracellular PPPSP motifs in the Wnt coreceptor LRP6
-
MacDonald, B.T., Yokota, C., Tamai, K. et al. (2008) Wnt signal amplification: activity, cooperativity and regulation of multiple intracellular PPPSP motifs in the Wnt coreceptor LRP6. The Journal of Biological Chemistry, 283, 16115-16123.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 16115-16123
-
-
MacDonald, B.T.1
Yokota, C.2
Tamai, K.3
-
72
-
-
84865457715
-
The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling
-
Macheda, M.L., Sun, W.W., Kugathasan, K. et al. (2012) The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling. The Journal of Biological Chemistry, 287, 29312-29323.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 29312-29323
-
-
Macheda, M.L.1
Sun, W.W.2
Kugathasan, K.3
-
73
-
-
0038515322
-
Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E
-
Magoori, K., Kang, M.J., Ito, M.R. et al. (2003) Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E. The Journal of Biological Chemistry, 278, 11331-11336.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 11331-11336
-
-
Magoori, K.1
Kang, M.J.2
Ito, M.R.3
-
74
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
Mao, J., Wang, J., Liu, B. et al. (2001a) Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Molecular Cell, 7, 801-809.
-
(2001)
Molecular Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
-
75
-
-
0035902050
-
LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins
-
Mao, B., Wu, W., Li, Y. et al. (2001b) LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins. Nature, 411, 321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
-
76
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/ beta-catenin signalling
-
Mao, B., Wu, W., Davidson, G. et al. (2002) Kremen proteins are Dickkopf receptors that regulate Wnt/ beta-catenin signalling. Nature, 417, 664-667.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
-
77
-
-
71449089518
-
Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range
-
Mii, Y. and Taira, M. (2009) Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range. Development, 136, 4083-4088.
-
(2009)
Development
, vol.136
, pp. 4083-4088
-
-
Mii, Y.1
Taira, M.2
-
78
-
-
0242719831
-
Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken
-
Moeller, C., Swindell, E.C., Kispert, A., and Eichele, G. (2003) Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken. Development, 130, 5103-5111.
-
(2003)
Development
, vol.130
, pp. 5103-5111
-
-
Moeller, C.1
Swindell, E.C.2
Kispert, A.3
Eichele, G.4
-
79
-
-
77954903507
-
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
-
Mukai, A., Yamamoto-Hino, M., Awano, W. et al. (2010) Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt. The EMBO Journal, 29, 2114-2125.
-
(2010)
The EMBO Journal
, vol.29
, pp. 2114-2125
-
-
Mukai, A.1
Yamamoto-Hino, M.2
Awano, W.3
-
80
-
-
18044399916
-
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse
-
Mukhopadhyay, M., Shtrom, S., Rodriguez-Esteban, C. et al. (2001) Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Developmental Cell, 1, 423-434.
-
(2001)
Developmental Cell
, vol.1
, pp. 423-434
-
-
Mukhopadhyay, M.1
Shtrom, S.2
Rodriguez-Esteban, C.3
-
81
-
-
84858611820
-
The origin and evolution of G proteincoupled receptor kinases
-
Mushegian, A., Gurevich, V.V., and Gurevich, E.V. (2012) The origin and evolution of G proteincoupled receptor kinases. PLoS One, 7, e33806.
-
(2012)
PLoS One
, vol.7
, pp. e33806
-
-
Mushegian, A.1
Gurevich, V.V.2
Gurevich, E.V.3
-
82
-
-
33846085476
-
Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos
-
Nagano, T., Takehara, S., Takahashi, M. et al. (2006) Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos. Development, 133, 4643-4654.
-
(2006)
Development
, vol.133
, pp. 4643-4654
-
-
Nagano, T.1
Takehara, S.2
Takahashi, M.3
-
83
-
-
84861994937
-
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes
-
Naito, A.T., Sumida, T., Nomura, S. et al. (2012) Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell, 149, 1298-1313.
-
(2012)
Cell
, vol.149
, pp. 1298-1313
-
-
Naito, A.T.1
Sumida, T.2
Nomura, S.3
-
84
-
-
33845359084
-
Function and biological roles of the Dickkopf family of Wnt modulators
-
Niehrs, C. (2006) Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene, 25, 7469-7481.
-
(2006)
Oncogene
, vol.25
, pp. 7469-7481
-
-
Niehrs, C.1
-
85
-
-
28644448036
-
Cell biology: relays at the membrane
-
Nusse, R. (2005) Cell biology: relays at the membrane. Nature, 438, 747-749.
-
(2005)
Nature
, vol.438
, pp. 747-749
-
-
Nusse, R.1
-
86
-
-
78649651742
-
Lrp4: a novel modulator of extracellular signaling in craniofacial organogenesis
-
Ohazama, A., Porntaveetus, T., Ota, M.S. et al. (2010) Lrp4: a novel modulator of extracellular signaling in craniofacial organogenesis. American Journal of Medical Genetics A, 152A, 2974-2983.
-
(2010)
American Journal of Medical Genetics A
, vol.152 A
, pp. 2974-2983
-
-
Ohazama, A.1
Porntaveetus, T.2
Ota, M.S.3
-
87
-
-
79952491185
-
Rspo3 binds Syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis
-
Ohkawara, B., Glinka, A., and Niehrs, C. (2011) Rspo3 binds Syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Developmental Cell, 20, 303-314.
-
(2011)
Developmental Cell
, vol.20
, pp. 303-314
-
-
Ohkawara, B.1
Glinka, A.2
Niehrs, C.3
-
88
-
-
10744219743
-
The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway
-
Oishi, I., Suzuki, H., Onishi, N. et al. (2003) The receptor tyrosine kinase Ror2 is involved in noncanonical Wnt5a/JNK signalling pathway. Genes to Cells, 8, 645-654.
-
(2003)
Genes to Cells
, vol.8
, pp. 645-654
-
-
Oishi, I.1
Suzuki, H.2
Onishi, N.3
-
89
-
-
51149123490
-
Wnt3amediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation
-
Pan, W., Choi, S-C., Wang, H. et al. (2008) Wnt3amediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science, 321, 1350-1353.
-
(2008)
Science
, vol.321
, pp. 1350-1353
-
-
Pan, W.1
Choi, S.-C.2
Wang, H.3
-
90
-
-
18344378499
-
Lipoprotein particles are required for Hedgehog and Wingless signalling
-
Panáková, D., Sprong, H., Marois, E. et al. (2005) Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature, 435, 58-65.
-
(2005)
Nature
, vol.435
, pp. 58-65
-
-
Panáková, D.1
Sprong, H.2
Marois, E.3
-
91
-
-
84862178250
-
The many roles of PTK7: a versatile regulator of cell-cell communication
-
Peradziryi, H., Tolwinski, N.S., and Borchers, A. (2012) The many roles of PTK7: a versatile regulator of cell-cell communication. Archives of Biochemistry and Biophysics, 524, 71-76.
-
(2012)
Archives of Biochemistry and Biophysics
, vol.524
, pp. 71-76
-
-
Peradziryi, H.1
Tolwinski, N.S.2
Borchers, A.3
-
92
-
-
0034643323
-
Specificities of heparan sulphate proteoglycans in developmental processes
-
Perrimon, N. and Bernfield, M. (2000) Specificities of heparan sulphate proteoglycans in developmental processes. Nature, 404, 725-728.
-
(2000)
Nature
, vol.404
, pp. 725-728
-
-
Perrimon, N.1
Bernfield, M.2
-
93
-
-
58149185151
-
Direct inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-catenin signaling
-
Piao, S., Lee, S-H., Kim, H. et al. (2008) Direct inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-catenin signaling. PLoS One, 3, e4046.
-
(2008)
PLoS One
, vol.3
, pp. e4046
-
-
Piao, S.1
Lee, S.-H.2
Kim, H.3
-
94
-
-
0034727078
-
An LDL-receptor-related protein mediates Wnt signalling in mice
-
Pinson, K.I., Brennan, J., Monkley, S. et al. (2000) An LDL-receptor-related protein mediates Wnt signalling in mice. Nature, 407, 535-538.
-
(2000)
Nature
, vol.407
, pp. 535-538
-
-
Pinson, K.I.1
Brennan, J.2
Monkley, S.3
-
95
-
-
0037162282
-
Casein kinase 1: a Wnt'er of disconnect
-
Polakis, P. (2002) Casein kinase 1: a Wnt'er of disconnect. Current Biology, 12, R499-R501.
-
(2002)
Current Biology
, vol.12
, pp. R499-R501
-
-
Polakis, P.1
-
96
-
-
78650905901
-
Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling
-
Puppo, F., Thomé, V., Lhoumeau, A.C. et al. (2011) Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling. EMBO Report, 12, 43-49.
-
(2011)
EMBO Report
, vol.12
, pp. 43-49
-
-
Puppo, F.1
Thomé, V.2
Lhoumeau, A.C.3
-
97
-
-
44849129873
-
A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling
-
Quélard, D., Lavergne, E., Hendaoui, I. et al. (2008) A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling. PLoS One, 3, e1878.
-
(2008)
PLoS One
, vol.3
, pp. e1878
-
-
Quélard, D.1
Lavergne, E.2
Hendaoui, I.3
-
98
-
-
0035200832
-
Carboxypeptidases from A to z: implications in embryonic development and Wnt binding
-
Reznik, S.E. and Fricker, L.D. (2001) Carboxypeptidases from A to z: implications in embryonic development and Wnt binding. Cellular and Molecular Life Sciences, 58, 1790-1804.
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, pp. 1790-1804
-
-
Reznik, S.E.1
Fricker, L.D.2
-
99
-
-
27744495867
-
SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor
-
Rodriguez, J., Esteve, P., Weinl, C. et al. (2005) SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor. Nature Neuroscience, 8, 1301-1309.
-
(2005)
Nature Neuroscience
, vol.8
, pp. 1301-1309
-
-
Rodriguez, J.1
Esteve, P.2
Weinl, C.3
-
100
-
-
76649119449
-
LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse
-
Sakane, H., Yamamoto, H., and Kikuchi, A. (2010) LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse. Journal of Cell Science, 123, 360-368.
-
(2010)
Journal of Cell Science
, vol.123
, pp. 360-368
-
-
Sakane, H.1
Yamamoto, H.2
Kikuchi, A.3
-
101
-
-
34247589181
-
Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway
-
Schambony, A. and Wedlich, D. (2007) Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. Developmental Cell, 12, 779-792.
-
(2007)
Developmental Cell
, vol.12
, pp. 779-792
-
-
Schambony, A.1
Wedlich, D.2
-
102
-
-
0037701521
-
LDL receptor relatives at the crossroad of endocytosis and signaling
-
Schneider, W.J. and Nimpf, J. (2003) LDL receptor relatives at the crossroad of endocytosis and signaling. Cellular and Molecular Life Sciences, 60, 892-903.
-
(2003)
Cellular and Molecular Life Sciences
, vol.60
, pp. 892-903
-
-
Schneider, W.J.1
Nimpf, J.2
-
103
-
-
78650150896
-
International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors
-
Schulte, G. (2010) International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors. Pharmacological Reviews, 62, 632-667.
-
(2010)
Pharmacological Reviews
, vol.62
, pp. 632-667
-
-
Schulte, G.1
-
104
-
-
34249890531
-
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
-
Schwarz-Romond, T., Fiedler, M., Shibata, N. et al. (2007) The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization. Nature Structural and Molecular Biology, 14, 484-492.
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, pp. 484-492
-
-
Schwarz-Romond, T.1
Fiedler, M.2
Shibata, N.3
-
105
-
-
33845994036
-
LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST
-
Semenov, M.V. and He, X. (2006) LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST. The Journal of Biological Chemistry, 281, 38276-38284.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 38276-38284
-
-
Semenov, M.V.1
He, X.2
-
106
-
-
22844445934
-
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
-
Semenov, M., Tamai, K., and He, X. (2005) SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. The Journal of Biological Chemistry, 280, 26770-26775.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 26770-26775
-
-
Semenov, M.1
Tamai, K.2
He, X.3
-
107
-
-
84879422644
-
Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway
-
Skalka, N., Caspi, M., Caspi, E. et al. (2012) Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway. Oncogene, 32, 2836-2847.
-
(2012)
Oncogene
, vol.32
, pp. 2836-2847
-
-
Skalka, N.1
Caspi, M.2
Caspi, E.3
-
108
-
-
33947533683
-
Mutational analysis of Norrin-Frizzled4 recognition
-
Smallwood, P.M., Williams, J., Xu, Q. et al. (2007) Mutational analysis of Norrin-Frizzled4 recognition. The Journal of Biological Chemistry, 282, 4057-4068.
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 4057-4068
-
-
Smallwood, P.M.1
Williams, J.2
Xu, Q.3
-
109
-
-
8244240418
-
Targeting G protein-coupled receptor kinases to their receptor substrates
-
Stoffel, R.H., Pitcher, J.A., and Lefkowitz, R.J. (1997) Targeting G protein-coupled receptor kinases to their receptor substrates. Journal of Membrane Biology, 157, 1-8.
-
(1997)
Journal of Membrane Biology
, vol.157
, pp. 1-8
-
-
Stoffel, R.H.1
Pitcher, J.A.2
Lefkowitz, R.J.3
-
110
-
-
0028030060
-
Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family
-
Stoffel, R.H., Randall, R.R., Premont, R.T. et al. (1994) Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family. The Journal of Biological Chemistry, 269, 27791-27794.
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 27791-27794
-
-
Stoffel, R.H.1
Randall, R.R.2
Premont, R.T.3
-
111
-
-
84855814436
-
Wnt4 participates in the formation of vertebrate neuromuscular junction
-
Strochlic, L., Falk, J., Goillot, E. et al. (2012) Wnt4 participates in the formation of vertebrate neuromuscular junction. PLoS One, 7, e29976.
-
(2012)
PLoS One
, vol.7
, pp. e29976
-
-
Strochlic, L.1
Falk, J.2
Goillot, E.3
-
112
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
Taelman, V.F., Dobrowolski, R. Plouhinec, J.L. et al. (2010) Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell, 143, 1136-1148.
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
Dobrowolski, R.2
Plouhinec, J.L.3
-
113
-
-
0034727104
-
LDLreceptor- related proteins in Wnt signal transduction
-
Tamai, K., Semenov, M., Kato, Y. et al. (2000) LDLreceptor- related proteins in Wnt signal transduction. Nature, 407, 530-535.
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
Semenov, M.2
Kato, Y.3
-
114
-
-
1642564513
-
A mechanism for Wnt coreceptor activation
-
Tamai, K., Zeng, X., Liu, C. et al. (2004) A mechanism for Wnt coreceptor activation. Molecular Cell, 13, 149-156.
-
(2004)
Molecular Cell
, vol.13
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
-
115
-
-
79955009076
-
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation
-
Tanneberger, K., Pfister, A., Brauburger, K. et al. (2011) Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation. The EMBO Journal, 30, 1433-1443.
-
(2011)
The EMBO Journal
, vol.30
, pp. 1433-1443
-
-
Tanneberger, K.1
Pfister, A.2
Brauburger, K.3
-
116
-
-
84859464757
-
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
-
Tauriello, D.V.F., Jordens, I., Kirchner, K. et al. (2012) Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled. Proceedings of the National Academy of Sciences of the United States of America, 109, E812-E820.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. E812-E820
-
-
Tauriello, D.V.F.1
Jordens, I.2
Kirchner, K.3
-
117
-
-
0037343952
-
Wg/ Wnt signal can be transmitted through arrow/ LRP5,6 and Axin independently of Zw3/Gsk3beta activity
-
Tolwinski, N.S., Wehrli, M., Rives, A. et al. (2003) Wg/ Wnt signal can be transmitted through arrow/ LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Developmental Cell, 4, 407-418.
-
(2003)
Developmental Cell
, vol.4
, pp. 407-418
-
-
Tolwinski, N.S.1
Wehrli, M.2
Rives, A.3
-
118
-
-
0023216739
-
Directional noncell autonomy and the transmission of polarity information by the frizzled gene of Drosophila
-
Vinson, C.R. and Adler, P.N. (1987) Directional noncell autonomy and the transmission of polarity information by the frizzled gene of Drosophila. Nature, 329, 549-551.
-
(1987)
Nature
, vol.329
, pp. 549-551
-
-
Vinson, C.R.1
Adler, P.N.2
-
119
-
-
55749091843
-
Parathyroid hormone signaling through low-density lipoproteinrelated protein 6
-
Wan, M., Yang, C., Li, J. et al. (2008) Parathyroid hormone signaling through low-density lipoproteinrelated protein 6. Genes & Development, 22, 2968-2979.
-
(2008)
Genes & Development
, vol.22
, pp. 2968-2979
-
-
Wan, M.1
Yang, C.2
Li, J.3
-
120
-
-
58649119034
-
Carboxypeptidase Z (CPZ) links thyroid hormone and Wnt signaling pathways in growth plate chondrocytes
-
Wang, L., Shao, Y.Y., and Ballock, R.T. (2009) Carboxypeptidase Z (CPZ) links thyroid hormone and Wnt signaling pathways in growth plate chondrocytes. Journal of Bone and Mineral Research, 24, 265-273.
-
(2009)
Journal of Bone and Mineral Research
, vol.24
, pp. 265-273
-
-
Wang, L.1
Shao, Y.Y.2
Ballock, R.T.3
-
121
-
-
0030892061
-
Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8
-
Wang, S., Krinks, M., Lin, K. et al. (1997) Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell, 88, 757-766.
-
(1997)
Cell
, vol.88
, pp. 757-766
-
-
Wang, S.1
Krinks, M.2
Lin, K.3
-
122
-
-
33846155569
-
LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction
-
Weatherbee, S.D., Anderson, K.V., and Niswander, L.A. (2006) LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development, 133, 4993-5000.
-
(2006)
Development
, vol.133
, pp. 4993-5000
-
-
Weatherbee, S.D.1
Anderson, K.V.2
Niswander, L.A.3
-
123
-
-
0034727099
-
Arrow encodes an LDL-receptor-related protein essential for Wingless signalling
-
Wehrli, M., Dougan, S.T., Caldwell, K. et al. (2000) Arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature, 407, 527-530.
-
(2000)
Nature
, vol.407
, pp. 527-530
-
-
Wehrli, M.1
Dougan, S.T.2
Caldwell, K.3
-
124
-
-
48249092251
-
Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system
-
Wouda, R.R., Bansraj, M.R.K.S., de Jong, A.W.M. et al. (2008) Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system. Development, 135, 2277-2287.
-
(2008)
Development
, vol.135
, pp. 2277-2287
-
-
Wouda, R.R.1
Bansraj, M.R.K.S.2
de Jong, A.W.M.3
-
125
-
-
62849125293
-
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6
-
Wu, G., Huang, H., Garcia Abreu, J., and He, X. (2009) Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One, 4, e4926.
-
(2009)
PLoS One
, vol.4
, pp. e4926
-
-
Wu, G.1
Huang, H.2
Garcia Abreu, J.3
He, X.4
-
126
-
-
0032482447
-
The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases
-
Xu, Y.K. and Nusse, R. (1998) The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases. Current Biology, 8, R405-R406.
-
(1998)
Current Biology
, vol.8
, pp. R405-R406
-
-
Xu, Y.K.1
Nusse, R.2
-
127
-
-
12144289950
-
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand- receptor pair
-
Xu, Q., Wang, Y., Dabdoub, A. et al. (2004) Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand- receptor pair. Cell, 116, 883-895.
-
(2004)
Cell
, vol.116
, pp. 883-895
-
-
Xu, Q.1
Wang, Y.2
Dabdoub, A.3
-
128
-
-
12944308329
-
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF
-
Yamamoto, A., Nagano, T., Takehara, S. et al. (2005) Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. Cell, 120, 223-235.
-
(2005)
Cell
, vol.120
, pp. 223-235
-
-
Yamamoto, A.1
Nagano, T.2
Takehara, S.3
-
129
-
-
46049089076
-
Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling
-
Yamamoto, H., Sakane, H., Yamamoto, H. et al. (2008) Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling. Developmental Cell, 15, 37-48.
-
(2008)
Developmental Cell
, vol.15
, pp. 37-48
-
-
Yamamoto, H.1
Sakane, H.2
Yamamoto, H.3
-
130
-
-
33744964883
-
Phosphorylation of frizzled-3
-
Yanfeng, W.A., Tan, C., Fagan, R.J., and Klein, P.S. (2006) Phosphorylation of frizzled-3. The Journal of Biological Chemistry, 281, 11603-11609.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 11603-11609
-
-
Yanfeng, W.A.1
Tan, C.2
Fagan, R.J.3
Klein, P.S.4
-
131
-
-
0030265570
-
A frizzled homolog functions in a vertebrate Wnt signaling pathway
-
Yang-Snyder, J., Miller, J.R., Brown, J.D. et al. (1996) A frizzled homolog functions in a vertebrate Wnt signaling pathway. Current Biology, 6, 1302-1306.
-
(1996)
Current Biology
, vol.6
, pp. 1302-1306
-
-
Yang-Snyder, J.1
Miller, J.R.2
Brown, J.D.3
-
132
-
-
62049083647
-
The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors
-
Yum, S., Lee, S-J., Piao, S. et al. (2009) The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors. Biochemical and Biophysical Research Communications, 381, 345-349.
-
(2009)
Biochemical and Biophysical Research Communications
, vol.381
, pp. 345-349
-
-
Yum, S.1
Lee, S.-J.2
Piao, S.3
-
133
-
-
28644439005
-
A dualkinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng, X., Tamai, K., Doble, B. et al. (2005) A dualkinase mechanism for Wnt co-receptor phosphorylation and activation. Nature, 438, 873-877.
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
-
134
-
-
38949194936
-
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
Zeng, X., Huang, H., Tamai, K. et al. (2008) Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development, 135, 367-375.
-
(2008)
Development
, vol.135
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
-
135
-
-
11144248964
-
Extensive phosphorylation of Smoothened in Hedgehog pathway activation
-
Zhang, C., Williams, E.H., Guo, Y. et al. (2004) Extensive phosphorylation of Smoothened in Hedgehog pathway activation. Proceedings of the National Academy of Sciences of the United States of America, 101, 17900-17907.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 17900-17907
-
-
Zhang, C.1
Williams, E.H.2
Guo, Y.3
-
136
-
-
33749511242
-
Regulation of wingless signaling by the CKI family in Drosophila limb development
-
Zhang, L., Jia, J., Wang, B. et al. (2006) Regulation of wingless signaling by the CKI family in Drosophila limb development. Developmental Biology, 299, 221-237.
-
(2006)
Developmental Biology
, vol.299
, pp. 221-237
-
-
Zhang, L.1
Jia, J.2
Wang, B.3
-
137
-
-
84856563661
-
Wnt proteins regulate acetylcholine receptor clustering in muscle cells
-
Zhang, B., Liang, C., Bates, R. et al. (2012) Wnt proteins regulate acetylcholine receptor clustering in muscle cells. Molecular Brain, 5, 7.
-
(2012)
Molecular Brain
, vol.5
, pp. 7
-
-
Zhang, B.1
Liang, C.2
Bates, R.3
|