LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST

Journal of Biological Chemistry

Volumn 281, Issue 50, 2006, Pages 38276-38284

  Semenov, Mikhail V ^a,b   He, Xi ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE HOMEOSTASIS; MUTATIONS; SCLEROSTEOSIS;

BONE; CHEMICAL BONDS; DISEASES; ENZYME INHIBITION; GROWTH KINETICS;

GENETIC ENGINEERING;

LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; PROTEIN DKK 1; SCLEROSTIN; UNCLASSIFIED DRUG; WNT 10B PROTEIN; WNT 6 PROTEIN; WNT PROTEIN;

ARTICLE; BONE DISEASE; BONE GROWTH; BONE MASS; CONTROLLED STUDY; DRUG ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; HIGH BONE MASS DISEASE; HUMAN; HUMAN CELL; OSTEOPOROSIS; OSTEOSCLEROSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

BONE DISEASES; BONE MORPHOGENETIC PROTEINS; CELL LINE; DNA, COMPLEMENTARY; GENETIC MARKERS; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MUTATION; PROTEIN BINDING;

EID: 33845994036     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609509200     Document Type: Article

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