Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 14, 2012, Pages

  Tauriello, Daniele V F ^a,e   Jordens, Ingrid ^a   Kirchner, Katharina ^b   Slootstra, Jerry W ^c   Kruitwagen, Tom ^a   Bouwman, Britta A M ^a   Noutsou, Maria ^a   Rüdiger, Stefan G D ^d   Schwamborn, Klaus ^c   Schambony, Alexandra ^b   Maurice, Madelon M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c Pepscan Systems   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

^e INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

Peptide microarray; Protein protein interaction; Wingless signaling

Indexed keywords

BETA CATENIN; DNA; FRIZZLED PROTEIN; SYNTHETIC PEPTIDE; WNT PROTEIN;

ARTICLE; CELL STRAIN HEK293; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MICROARRAY; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; XENOPUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BETA CATENIN; CELL LINE; FLUORESCENCE POLARIZATION; FRIZZLED RECEPTORS; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN BINDING; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 84859464757     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114802109     Document Type: Article

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