Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span

Genes and Development

Volumn 29, Issue 7, 2015, Pages 718-731

  Pu, Mintie ^a   Ni, Zhuoyu ^a   Wang, Minghui ^a   Wang, Xiujuan ^a   Wood, Jason G ^b   Helfand, Stephen L ^b   Yu, Haiyuan ^a   Lee, Siu Sylvia ^a  

^a Department of Obstetrics Gynecology   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Aging; Epigenetics; Gene expression; H3K36me3; met 1

Indexed keywords

HISTONE H3; LYSINE; MESSENGER RNA; METHYLTRANSFERASE; HISTONE;

3' UNTRANSLATED REGION; ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DROSOPHILA MELANOGASTER; EXON; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GERM CELL; HISTONE METHYLATION; INNATE IMMUNITY; LIFESPAN; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; RNA PROCESSING; RNA STABILITY; SOMATIC CELL; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION TERMINATION; ANIMAL; GENETICS; METABOLISM; METHYLATION; PHYSIOLOGY;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HISTONES; LONGEVITY; LYSINE; METHYLATION;

EID: 84926361022     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.254144.114     Document Type: Article

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