Genotype-property patient-phenotype relations suggest that proteome exhaustion can cause amyotrophic lateral sclerosis

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Kepp, Kasper P ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; PROTEASOME; PROTEASOME INHIBITOR; ISOPROTEIN; PROTEOME; SOD1 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; GENETIC RISK; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MISSENSE MUTATION; MITOCHONDRIAL RESPIRATION; MOTONEURON; NERVE DEGENERATION; NEUROMUSCULAR SYNAPSE; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN MISFOLDING; PROTEIN MODIFICATION; PROTEIN STABILITY; RESTING ENERGY EXPENDITURE; RNA METABOLISM; SURVIVAL TIME; ADOLESCENT; ADULT; AGED; CHEMISTRY; DEGENERATIVE DISEASE; GENETICS; GENOTYPE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; PHENOTYPE; PROTEIN FOLDING; SURVIVAL ANALYSIS;

ADOLESCENT; ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; GENOTYPE; HUMANS; MIDDLE AGED; MOTOR NEURONS; MUTATION; NEURODEGENERATIVE DISEASES; PHENOTYPE; PROTEIN FOLDING; PROTEIN ISOFORMS; PROTEOME; RNA, MESSENGER; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE-1; SURVIVAL ANALYSIS;

EID: 84925748556     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118649     Document Type: Article

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