Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice

European Journal of Neuroscience

Volumn 14, Issue 12, 2001, Pages 2032-2036

  Fukada, Kei ^a   Nagano, Seiichi ^a   Satoh, Masahiko ^b   Tohyama, Chiharu ^b   Nakanishi, Toyofumi ^c   Shimizu, Akira ^c   Yanagihara, Takehiko ^a   Sakoda, Saburo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Cu Zn superoxide dismutase; Mass spectrometry; Metallothionein; Transgenic mice

Indexed keywords

COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; METALLOTHIONEIN; MUTANT PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FAMILIAL DISEASE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE MUTATION; GENETIC STABILITY; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPINAL CORD; TRANSGENIC MOUSE; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; FEMALE; FREE RADICALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; METALLOTHIONEIN; MICE; MICE, NEUROLOGIC MUTANTS; MICE, TRANSGENIC; MUTATION; OXIDATIVE STRESS; SPINAL CORD; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 0035783937     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01828.x     Document Type: Article

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