Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2210-2215

  Vassall, Kenrick A ^a   Stubbs, Helen R ^a   Primmer, Heather A ^a   Tong, Ming Sze ^a   Sullivan, Sarah M ^a   Sobering, Ryan ^a,d   Srinivasan, Saipraveen ^c   Briere, Lee Ann K ^b   Dunn, Stanley D ^b   Colón, Wilfredo ^c   Meiering, Elizabeth M ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c Research Rensselaer Polytechnic Institute   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; COPPER ZINC SUPEROXIDE DISMUTASE; CYSTEINE; SERINE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISEASE DURATION; DISEASE SEVERITY; ENZYME DENATURATION; LIGHT SCATTERING; MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN STABILITY; QUANTITATIVE ANALYSIS; THERMODYNAMICS; ULTRACENTRIFUGATION;

AMYOTROPHIC LATERAL SCLEROSIS; ENZYME STABILITY; HOT TEMPERATURE; HUMANS; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; SUPEROXIDE DISMUTASE;

EID: 79952308169     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0913021108     Document Type: Article

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