Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

Journal of Neuroscience

Volumn 34, Issue 23, 2014, Pages 8021-8031

  Roberts, Blaine R ^a   Lim, Nastasia K H ^a   McAllum, Erin J ^a   Donnelly, Paul S ^a,b   Hare, Dominic J ^a,c   Doble, Philip A ^c   Turner, Bradley J ^a   Price, Katherine A ^a,j   Lim, Sin Chun ^a,b   Paterson, Brett M ^a,b   Hickey, James L ^a,b   Rhoads, Timothy W ^d,e   Williams, Jared R ^d,e   Kanninen, Katja M ^a,i   Hung, Lin W ^a,b   Liddell, Jeffrey R ^a   Grubman, Alexandra ^a   Monty, Jean Francois ^f   Llanos, Roxana M ^f   Kramer, David R ^g   Mercer, Julian F B ^f   Bush, Ashley I ^a   Masters, Colin L ^a   Duce, James A ^a,h   Li, Qiao Xin ^a   Beckman, Joseph S ^d,e   Barnham, Kevin J ^a,b   White, Anthony R ^a   Crouch, Peter J ^a   more..

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^d OREGON STATE UNIVERSITY   (United States)

^e OREGON STATE UNIVERSITY   (United States)

^f DEAKIN UNIVERSITY   (Australia)

^g The Australian National University   (Australia)

^h UNIVERSITY OF LEEDS   (United Kingdom)

ⁱ UNIVERSITY OF EASTERN FINLAND   (Finland)

^j MOUNT SINAI SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; COPPER DERIVATIVE; COPPER TRANSPORTER 1; COPPER ZINC SUPEROXIDE DISMUTASE; DIACETYLBIS (4 METHYLTHIOSEMICARBAZONATO) COPPER; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GEL PERMEATION CHROMATOGRAPHY; GENOTYPE; LOCOMOTION; MALE; MASS SPECTROMETRY; MOTONEURON; MOUSE; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; NEUROPROTECTION; NONHUMAN; OXIDATION; PARALYSIS; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FOLDING; SPINAL CORD;

ADMINISTRATION, ORAL; AGE FACTORS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CATION TRANSPORT PROTEINS; CHROMATOGRAPHY, GEL; DISEASE MODELS, ANIMAL; HUMANS; LOCOMOTION; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION; ORGANOMETALLIC COMPOUNDS; PHENOTYPE; SPINAL CORD; SUPEROXIDE DISMUTASE; THIOSEMICARBAZONES;

EID: 84901765769     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4196-13.2014     Document Type: Article

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