Wogonin Protects Rat Dorsal Root Ganglion Neurons Against Tunicamycin-Induced ER Stress Through the PERK-eIF2α-ATF4 Signaling Pathway

Journal of Molecular Neuroscience

Volumn 55, Issue 4, 2015, Pages 995-1005

  Chen, Fangyi ^a   Wu, Rongbo ^a   Zhu, Zhu ^b   Yin, Wangping ^a   Xiong, Min ^a   Sun, Jianwei ^a   Ni, Miaozhong ^a   Cai, Guoping ^a   Zhang, Xinchao ^a  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Xinhua Street Community Health Service Center ^*  (China)

Author keywords

DRG neurons; ER stress; PERK eIF2 signaling pathway; Wogonin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 12; DNA NUCLEOTIDYLEXOTRANSFERASE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TUNICAMYCIN; WOGONIN; ATF4 PROTEIN, RAT; FLAVANONE DERIVATIVE; INITIATION FACTOR 2; NEUROPROTECTIVE AGENT; PERK KINASE; PROTEIN KINASE R;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMBRYO; ENDOPLASMIC RETICULUM STRESS; IN VITRO STUDY; LIPID PEROXIDATION; NERVE GROWTH; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL GANGLION; ANIMAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; SENSORY NERVE CELL; SPRAGUE DAWLEY RAT;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; APOPTOSIS; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; FLAVANONES; GANGLIA, SPINAL; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; TUNICAMYCIN;

EID: 84925496494     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0456-7     Document Type: Article

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