Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway

Acta Pharmacologica Sinica

Volumn 32, Issue 12, 2011, Pages 1475-1482

  Liu, Yu Min ^a   Wang, Xiong ^b   Nawaz, Ahmed ^c   Kong, Zhao Hong ^a   Hong, Yan ^a   Wang, Chang Hua ^c   Zhang, Jun Jian ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

apoptosis; atherosclerosis; diacylglycerol (DAG); endoplasmic reticulum stress; palmitate; PKC; vascular smooth muscle cells; wogonin

Indexed keywords

4 PHENYLBUTYRIC ACID; DIACYLGLYCEROL; PALMITIC ACID; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; SCUTELLARIA BAICALENSIS EXTRACT; WOGONIN;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; ENDOPLASMIC RETICULUM STRESS; LIPOTOXICITY; NICK END LABELING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SCUTELLARIA BAICALENSIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; DIGLYCERIDES; FLAVANONES; MUSCLE, SMOOTH, VASCULAR; PHENYLBUTYRATES; PROTEIN KINASE C; RATS; REACTIVE OXYGEN SPECIES;

EID: 82955194996     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.120     Document Type: Article

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