Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

Nature

Volumn 519, Issue 7541, 2015, Pages 97-101

  Ewald, Collin Y ^a,b,c   Landis, Jess N ^d   Abate, Jess Porter ^a,b,c   Murphy, Coleen T ^d   Blackwell, T Keith ^a,b,c  

^a JOSLIN DIABETES CENTER   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; INSULIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR NRF2; CAENORHABDITIS ELEGANS PROTEIN; DAF-16 PROTEIN, C ELEGANS; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; SKN-1 PROTEIN, C ELEGANS; TRANSCRIPTION FACTOR;

ARTICLE; CAENORHABDITIS ELEGANS; CELL AGING; CELL SURVIVAL; EXTRACELLULAR MATRIX; LIFE EXTENSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGING; ANIMAL; BIOSYNTHESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; LONGEVITY; METABOLISM; PHYSIOLOGY;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; COLLAGEN; DNA-BINDING PROTEINS; EXTRACELLULAR MATRIX; FORKHEAD TRANSCRIPTION FACTORS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LARVA; LONGEVITY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84925488579     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14021     Document Type: Article

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