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Volumn 466, Issue 7305, 2010, Pages 498-502

A new DAF-16 isoform regulates longevity

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO;

EID: 77954959936     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09184     Document Type: Article
Times cited : (151)

References (30)
  • 1
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • Calnan, D. R. & Brunet, A. The FoxO code. Oncogene 27, 2276-2288 (2008).
    • (2008) Oncogene , vol.27 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 2
    • 34848911606 scopus 로고    scopus 로고
    • Genetics of aging in Caenorhabditis elegans
    • Antebi, A. Genetics of aging in Caenorhabditis elegans. PLoS Genet. 3, e129 (2007).
    • (2007) PLoS Genet. , vol.3
    • Antebi, A.1
  • 3
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon, C. J. The genetics of ageing. Nature 464, 504-512 (2010).
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 4
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin, K., Dorman, J. B., Rodan, A. & Kenyon, C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322 (1997).
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 5
    • 0030659557 scopus 로고    scopus 로고
    • The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg, S. et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999 (1997).
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1
  • 8
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin, K., Hsin, H., Libina, N. & Kenyon, C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nature Genet. 28, 139-145 (2001).
    • (2001) Nature Genet. , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 9
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson, S. T. & Johnson, T. E. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr. Biol. 11, 1975-1980 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 10
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee, R. Y., Hench, J. & Ruvkun, G. Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr. Biol. 11, 1950-1957 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 11
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
    • Libina, N., Berman, J. R. & Kenyon, C. Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115, 489-502 (2003).
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 12
    • 41849087003 scopus 로고    scopus 로고
    • FOXO animal models reveal a variety of diverse roles for FOXO transcription factors
    • Arden, K. C. FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene 27, 2345-2350 (2008).
    • (2008) Oncogene , vol.27 , pp. 2345-2350
    • Arden, K.C.1
  • 13
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
    • Oh, S. W. et al. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc. Natl Acad. Sci. USA 102, 4494-4499 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4494-4499
    • Oh, S.W.1
  • 14
    • 33646934067 scopus 로고    scopus 로고
    • A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
    • Lehtinen, M. K. et al. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001 (2006).
    • (2006) Cell , vol.125 , pp. 987-1001
    • Lehtinen, M.K.1
  • 15
    • 33744976074 scopus 로고    scopus 로고
    • Elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
    • Berdichevsky, A., Viswanathan, M., Horvitz, H. R. & Guarente, L. C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. Cell 125, 1165-1177 (2006).
    • (2006) Cell , vol.125 , pp. 1165-1177
    • Berdichevsky, A.1    Viswanathan, M.2    Horvitz, H.R.3    Guarente, L.C.4
  • 16
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • Brunet, A. et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015 (2004).
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1
  • 17
    • 0037466652 scopus 로고    scopus 로고
    • DAF-16 target genes that control C. elegans life-span and metabolism
    • Lee, S. S., Kennedy, S., Tolonen, A. C. & Ruvkun, G. DAF-16 target genes that control C. elegans life-span and metabolism. Science 300, 644-647 (2003).
    • (2003) Science , vol.300 , pp. 644-647
    • Lee, S.S.1    Kennedy, S.2    Tolonen, A.C.3    Ruvkun, G.4
  • 18
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee, J., Bubb, K. & Thomas, J. H. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2, 111-121 (2003).
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 19
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy, C. T. et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-283 (2003).
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1
  • 20
    • 0029443155 scopus 로고
    • Mosaic analysis
    • Herman, R. K. Mosaic analysis. Methods Cell Biol. 48, 123-146 (1995).
    • (1995) Methods Cell Biol. , vol.48 , pp. 123-146
    • Herman, R.K.1
  • 21
    • 61349123235 scopus 로고    scopus 로고
    • A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation
    • Padmanabhan, S. et al. A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation. Cell 136, 939-951 (2009).
    • (2009) Cell , vol.136 , pp. 939-951
    • Padmanabhan, S.1
  • 22
    • 0001104583 scopus 로고    scopus 로고
    • eds Riddle, D. L., Blumenthal, T., Meyer, B. J. & Priess, J. R. Cold Spring Harbor Laboratory Press
    • Riddle, D. L. & Albert, P. S. in C. elegans II (eds Riddle, D. L., Blumenthal, T., Meyer, B. J. & Priess, J. R.) 739-768 (Cold Spring Harbor Laboratory Press, 1997).
    • (1997) C. Elegans II , pp. 739-768
    • Riddle, D.L.1    Albert, P.S.2
  • 23
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda, Y. & Honda, S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13, 1385-1393 (1999).
    • (1999) FASEB J. , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 24
    • 0030014296 scopus 로고    scopus 로고
    • A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    • Murakami, S. & Johnson, T. E. A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics 143, 1207-1218 (1996).
    • (1996) Genetics , vol.143 , pp. 1207-1218
    • Murakami, S.1    Johnson, T.E.2
  • 25
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptorlike gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura, K. D., Tissenbaum, H. A., Liu, Y. & Ruvkun, G. daf-2, an insulin receptorlike gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277, 942-946 (1997).
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 26
    • 61449244533 scopus 로고    scopus 로고
    • Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
    • Soukas, A. A., Kane, E. A., Carr, C. E., Melo, J. A. & Ruvkun, G. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 23, 496-511 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 496-511
    • Soukas, A.A.1    Kane, E.A.2    Carr, C.E.3    Melo, J.A.4    Ruvkun, G.5
  • 27
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Oh, S. W. et al. Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nature Genet. 38, 251-257 (2005).
    • (2005) Nature Genet. , vol.38 , pp. 251-257
    • Oh, S.W.1
  • 28
    • 38449085292 scopus 로고    scopus 로고
    • Maintenance of C. elegans
    • doi:10.1895/wormbook.1.101.1
    • Stiernagle, T. Maintenance of C. elegans. WormBook. doi:10.1895/wormbook. 1.101.1 (2006).
    • (2006) WormBook
    • Stiernagle, T.1
  • 29
    • 0019949378 scopus 로고
    • Life span of the wild and mutant nematode Caenorhabditis elegans. Effects of sex, sterilization, and temperature
    • Hosono, R., Mitsui, Y., Sato, Y., Aizawa, S. & Miwa, J. Life span of the wild and mutant nematode Caenorhabditis elegans. Effects of sex, sterilization, and temperature. Exp. Gerontol. 17, 163-172 (1982).
    • (1982) Exp. Gerontol. , vol.17 , pp. 163-172
    • Hosono, R.1    Mitsui, Y.2    Sato, Y.3    Aizawa, S.4    Miwa, J.5
  • 30
    • 0025942107 scopus 로고
    • Efficient gene transfer in C.elegans: Extrachromosomal maintenance and integration of transforming sequences
    • Mello, C. C., Kramer, J. M., Stinchcomb, D. & Ambros, V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10, 3959-3970 (1991).
    • (1991) EMBO J. , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4


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