-
1
-
-
0027157692
-
A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain
-
Johnson, J. D., Edman, J. C., and Rutter, W. J. (1993) A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain. Proc. Natl. Acad. Sci. U.S.A. 90, 5677-5681
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 5677-5681
-
-
Johnson, J.D.1
Edman, J.C.2
Rutter, W.J.3
-
2
-
-
0027437634
-
Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues
-
Di Marco, E., Cutuli, N., Guerra, L., Cancedda, R., and De Luca, M. (1993) Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues. J. Biol. Chem. 268, 24290-24295
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24290-24295
-
-
Di Marco, E.1
Cutuli, N.2
Guerra, L.3
Cancedda, R.4
De Luca, M.5
-
3
-
-
0027304064
-
NEP: A novel receptorlike tyrosine kinase expressed in proliferating neuroepithelia
-
Zerlin, M., Julius, M. A., and Goldfarb, M. (1993) NEP: a novel receptorlike tyrosine kinase expressed in proliferating neuroepithelia. Oncogene 8, 2731-2739
-
(1993)
Oncogene
, vol.8
, pp. 2731-2739
-
-
Zerlin, M.1
Julius, M.A.2
Goldfarb, M.3
-
4
-
-
0029987919
-
Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines
-
Perez, J. L., Jing, S. Q., and Wong, T. W. (1996) Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines. Oncogene 12, 1469-1477
-
(1996)
Oncogene
, vol.12
, pp. 1469-1477
-
-
Perez, J.L.1
Jing, S.Q.2
Wong, T.W.3
-
5
-
-
0028143364
-
Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line
-
Laval, S., Butler, R., Shelling, A. N., Hanby, A. M., Poulsom, R., and Ganesan, T. S. (1994) Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line. Cell Growth Differ. 5, 1173-1183
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 1173-1183
-
-
Laval, S.1
Butler, R.2
Shelling, A.N.3
Hanby, A.M.4
Poulsom, R.5
Ganesan, T.S.6
-
6
-
-
0028325796
-
Multiple tyrosine protein kinases in rat hippocampal neurons: Isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain
-
Sánchez, M. P., Tapley, P., Saini, S. S., He, B., Pulido, D., and Barbacid, M. (1994) Multiple tyrosine protein kinases in rat hippocampal neurons: isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain. Proc. Natl. Acad. Sci. U.S.A. 91, 1819-1823
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 1819-1823
-
-
Sánchez, M.P.1
Tapley, P.2
Saini, S.S.3
He, B.4
Pulido, D.5
Barbacid, M.6
-
7
-
-
0028799694
-
Distinct structural characteristics of discoidin i subfamily receptor tyrosine kinases and complementary expression in human cancer
-
Alves, F., Vogel, W., Mossie, K., Millauer, B., Höfler, H., and Ullrich, A. (1995) Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer. Oncogene 10, 609-618
-
(1995)
Oncogene
, vol.10
, pp. 609-618
-
-
Alves, F.1
Vogel, W.2
Mossie, K.3
Millauer, B.4
Höfler, H.5
Ullrich, A.6
-
8
-
-
0031309902
-
The discoidin domain receptor tyrosine kinases are activated by collagen
-
Vogel, W., Gish, G. D., Alves, F., and Pawson, T. (1997) The discoidin domain receptor tyrosine kinases are activated by collagen. Mol. Cell 1, 13-23
-
(1997)
Mol. Cell
, vol.1
, pp. 13-23
-
-
Vogel, W.1
Gish, G.D.2
Alves, F.3
Pawson, T.4
-
9
-
-
80054036560
-
Transmembrane collagen receptors
-
Leitinger, B. (2011) Transmembrane collagen receptors. Annu. Rev. Cell Dev. Biol. 27, 265-290
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 265-290
-
-
Leitinger, B.1
-
10
-
-
84862305477
-
Discoidin domain receptor tyrosine kinases: New players in cancer progression
-
Valiathan, R. R., Marco, M., Leitinger, B., Kleer, C. G., and Fridman, R. (2012) Discoidin domain receptor tyrosine kinases: new players in cancer progression. Cancer Metastasis Rev. 31, 295-321
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 295-321
-
-
Valiathan, R.R.1
Marco, M.2
Leitinger, B.3
Kleer, C.G.4
Fridman, R.5
-
11
-
-
84871260039
-
A tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiation
-
Yeh, Y. C., Lin, H. H., and Tang, M. J. (2012) A tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiation. Am. J. Physiol. Cell. Physiol. 303, C1207-C1217
-
(2012)
Am. J. Physiol. Cell. Physiol.
, vol.303
-
-
Yeh, Y.C.1
Lin, H.H.2
Tang, M.J.3
-
12
-
-
0035344510
-
Identification of two novel, kinase-deficient variants of discoidin domain receptor 1: Differential expression in human colon cancer cell lines
-
Alves, F., Saupe, S., Ledwon, M., Schaub, F., Hiddemann, W., and Vogel, W. F. (2001) Identification of two novel, kinase-deficient variants of discoidin domain receptor 1: differential expression in human colon cancer cell lines. FASEB J. 15, 1321-1323
-
(2001)
FASEB J
, vol.15
, pp. 1321-1323
-
-
Alves, F.1
Saupe, S.2
Ledwon, M.3
Schaub, F.4
Hiddemann, W.5
Vogel, W.F.6
-
13
-
-
48249150751
-
Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
-
Jin, P., Zhang, J., Sumariwalla, P. F., Ni, I., Jorgensen, B., Crawford, D., Phillips, S., Feldmann, M., Shepard, H. M., and Paleolog, E. M. (2008) Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis. Arthritis Res. Ther. 10, R73
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Jin, P.1
Zhang, J.2
Sumariwalla, P.F.3
Ni, I.4
Jorgensen, B.5
Crawford, D.6
Phillips, S.7
Feldmann, M.8
Shepard, H.M.9
Paleolog, E.M.10
-
14
-
-
34548211773
-
Structural similarities and functional diversity of eukaryotic discoidin-like domains
-
Kiedzierska, A., Smietana, K., Czepczynska, H., and Otlewski, J. (2007) Structural similarities and functional diversity of eukaryotic discoidin-like domains. Biochim. Biophys. Acta 1774, 1069-1078
-
(2007)
Biochim. Biophys. Acta
, vol.1774
, pp. 1069-1078
-
-
Kiedzierska, A.1
Smietana, K.2
Czepczynska, H.3
Otlewski, J.4
-
15
-
-
0035824637
-
Mapping of epitopes in discoidin domain receptor 1 critical for collagen binding
-
Curat, C. A., Eck, M., Dervillez, X., and Vogel, W. F. (2001) Mapping of epitopes in discoidin domain receptor 1 critical for collagen binding. J. Biol. Chem. 276, 45952-45958
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45952-45958
-
-
Curat, C.A.1
Eck, M.2
Dervillez, X.3
Vogel, W.F.4
-
16
-
-
0038607924
-
Molecular analysis of collagen binding by the human discoidin domain receptors, DDR1 and DDR2. Identification of collagen binding sites in DDR2
-
Leitinger, B. (2003) Molecular analysis of collagen binding by the human discoidin domain receptors, DDR1 and DDR2. Identification of collagen binding sites in DDR2. J. Biol. Chem. 278, 16761-16769
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16761-16769
-
-
Leitinger, B.1
-
17
-
-
3843108034
-
Exploring the collagen-binding site of the DDR1 tyrosine kinase receptor
-
Abdulhussein, R., McFadden, C., Fuentes-Prior, P., and Vogel, W. F. (2004) Exploring the collagen-binding site of the DDR1 tyrosine kinase receptor. J. Biol. Chem. 279, 31462-31470
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31462-31470
-
-
Abdulhussein, R.1
McFadden, C.2
Fuentes-Prior, P.3
Vogel, W.F.4
-
18
-
-
78951473449
-
Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1
-
Xu, H., Raynal, N., Stathopoulos, S., Myllyharju, J., Farndale, R. W., and Leitinger, B. (2011) Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1. Matrix Biol. 30, 16-26
-
(2011)
Matrix Biol
, vol.30
, pp. 16-26
-
-
Xu, H.1
Raynal, N.2
Stathopoulos, S.3
Myllyharju, J.4
Farndale, R.W.5
Leitinger, B.6
-
19
-
-
34648819975
-
Structural basis of the collagen-binding mode of discoidin domain receptor 2
-
Ichikawa, O., Osawa, M., Nishida, N., Goshima, N., Nomura, N., and Shimada, I. (2007) Structural basis of the collagen-binding mode of discoidin domain receptor 2. EMBO J. 26, 4168-4176
-
(2007)
EMBO J
, vol.26
, pp. 4168-4176
-
-
Ichikawa, O.1
Osawa, M.2
Nishida, N.3
Goshima, N.4
Nomura, N.5
Shimada, I.6
-
20
-
-
71049118163
-
Crystallographic insight into collagen recognition by discoidin domain receptor 2
-
Carafoli, F., Bihan, D., Stathopoulos, S., Konitsiotis, A. D., Kvansakul, M., Farndale, R. W., Leitinger, B., and Hohenester, E. (2009) Crystallographic insight into collagen recognition by discoidin domain receptor 2. Structure 17, 1573-1581
-
(2009)
Structure
, vol.17
, pp. 1573-1581
-
-
Carafoli, F.1
Bihan, D.2
Stathopoulos, S.3
Konitsiotis, A.D.4
Kvansakul, M.5
Farndale, R.W.6
Leitinger, B.7
Hohenester, E.8
-
21
-
-
84859414321
-
Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling
-
Carafoli, F., Mayer, M. C., Shiraishi, K., Pecheva, M. A., Chan, L. Y., Nan, R., Leitinger, B., and Hohenester, E. (2012) Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling. Structure 20, 688-697
-
(2012)
Structure
, vol.20
, pp. 688-697
-
-
Carafoli, F.1
Mayer, M.C.2
Shiraishi, K.3
Pecheva, M.A.4
Chan, L.Y.5
Nan, R.6
Leitinger, B.7
Hohenester, E.8
-
22
-
-
0037070593
-
Ligand-induced shedding of discoidin domain receptor 1
-
Vogel, W. F. (2002) Ligand-induced shedding of discoidin domain receptor 1. FEBS Lett. 514, 175-180
-
(2002)
FEBS Lett
, vol.514
, pp. 175-180
-
-
Vogel, W.F.1
-
23
-
-
33646581410
-
Collagen type i selectively activates ectodomain shedding of the discoidin domain receptor 1: Involvement of Src tyrosine kinase
-
Slack, B. E., Siniaia, M. S., and Blusztajn, J. K. (2006) Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase. J. Cell. Biochem. 98, 672-684
-
(2006)
J. Cell. Biochem.
, vol.98
, pp. 672-684
-
-
Slack, B.E.1
Siniaia, M.S.2
Blusztajn, J.K.3
-
24
-
-
33747330131
-
A transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase DDR1
-
Noordeen, N. A., Carafoli, F., Hohenester, E., Horton, M. A., and Leitinger, B. (2006) A transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase DDR1. J. Biol. Chem. 281, 22744-22751
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 22744-22751
-
-
Noordeen, N.A.1
Carafoli, F.2
Hohenester, E.3
Horton, M.A.4
Leitinger, B.5
-
25
-
-
9644268238
-
Structural and evolutionary division of phosphotyrosine binding (PTB) domains
-
Uhlik, M. T., Temple, B., Bencharit, S., Kimple, A. J., Siderovski, D. P., and Johnson, G. L. (2005) Structural and evolutionary division of phosphotyrosine binding (PTB) domains. J. Mol. Biol. 345, 1-20
-
(2005)
J. Mol. Biol.
, vol.345
, pp. 1-20
-
-
Uhlik, M.T.1
Temple, B.2
Bencharit, S.3
Kimple, A.J.4
Siderovski, D.P.5
Johnson, G.L.6
-
26
-
-
79551594605
-
Protein kinases: Evolution of dynamic regulatory proteins
-
Taylor, S. S., and Kornev, A. P. (2011) Protein kinases: evolution of dynamic regulatory proteins. Trends Biochem. Sci. 36, 65-77
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 65-77
-
-
Taylor, S.S.1
Kornev, A.P.2
-
27
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
Zhang, J., Yang, P. L., and Gray, N. S. (2009) Targeting cancer with small molecule kinase inhibitors. Nat. Rev. Cancer 9, 28-39
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
28
-
-
0035185571
-
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase
-
Favelyukis, S., Till, J. H., Hubbard, S. R., and Miller, W. T. (2001) Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat. Struct. Biol. 8, 1058-1063
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 1058-1063
-
-
Favelyukis, S.1
Till, J.H.2
Hubbard, S.R.3
Miller, W.T.4
-
29
-
-
84867034578
-
The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition
-
Bertrand, T., Kothe, M., Liu, J., Dupuy, A., Rak, A., Berne, P. F., Davis, S., Gladysheva, T., Valtre, C., Crenne, J. Y., and Mathieu, M. (2012) The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition. J. Mol. Biol. 423, 439-453
-
(2012)
J. Mol. Biol.
, vol.423
, pp. 439-453
-
-
Bertrand, T.1
Kothe, M.2
Liu, J.3
Dupuy, A.4
Rak, A.5
Berne, P.F.6
Davis, S.7
Gladysheva, T.8
Valtre, C.9
Crenne, J.Y.10
Mathieu, M.11
-
30
-
-
55049111858
-
Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib
-
Day, E., Waters, B., Spiegel, K., Alnadaf, T., Manley, P. W., Buchdunger, E., Walker, C., and Jarai, G. (2008) Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib. Eur. J. Pharmacol. 599, 44-53
-
(2008)
Eur. J. Pharmacol.
, vol.599
, pp. 44-53
-
-
Day, E.1
Waters, B.2
Spiegel, K.3
Alnadaf, T.4
Manley, P.W.5
Buchdunger, E.6
Walker, C.7
Jarai, G.8
-
31
-
-
37049014938
-
Chemical proteomic profiles of the BCRABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets
-
Rix, U., Hantschel, O., Dürnberger, G., Remsing Rix, L. L., Planyavsky, M., Fernbach, N. V., Kaupe, I., Bennett, K. L., Valent, P., Colinge, J., Köcher, T., and Superti-Furga, G. (2007) Chemical proteomic profiles of the BCRABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood 110, 4055-4063
-
(2007)
Blood
, vol.110
, pp. 4055-4063
-
-
Rix, U.1
Hantschel, O.2
Dürnberger, G.3
Remsing Rix, L.L.4
Planyavsky, M.5
Fernbach, N.V.6
Kaupe, I.7
Bennett, K.L.8
Valent, P.9
Colinge, J.10
Köcher, T.11
Superti-Furga, G.12
-
32
-
-
84866709500
-
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
-
Hammerman, P. S., Sos, M. L., Ramos, A. H., Xu, C., Dutt, A., Zhou, W., Brace, L. E., Woods, B. A., Lin, W., Zhang, J., Deng, X., Lim, S. M., Heynck, S., Peifer, M., Simard, J. R., Lawrence, M. S., Onofrio, R. C., Salvesen, H. B., Seidel, D., Zander, T., Heuckmann, J. M., Soltermann, A., Moch, H., Koker, M., Leenders, F., Gabler, F., Querings, S., Ansén, S., Brambilla, E., Brambilla, C., Lorimier, P., Brustugun, O. T., Helland, A., Petersen, I., Clement, J. H., Groen, H., Timens, W., Sietsma, H., Stoelben, E., Wolf, J., Beer, D. G., Tsao, M. S., Hanna, M., Hatton, C., Eck, M. J., Janne, P. A., Johnson, B. E., Winckler, W., Greulich, H., Bass, A. J., and Cho, J. (2011) Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov. 1, 78-89
-
(2011)
Cancer Discov.
, vol.1
, pp. 78-89
-
-
Hammerman, P.S.1
Sos, M.L.2
Ramos, A.H.3
Xu, C.4
Dutt, A.5
Zhou, W.6
Brace, L.E.7
Woods, B.A.8
Lin, W.9
Zhang, J.10
Deng, X.11
Lim, S.M.12
Heynck, S.13
Peifer, M.14
Simard, J.R.15
Lawrence, M.S.16
Onofrio, R.C.17
Salvesen, H.B.18
Seidel, D.19
Zander, T.20
Heuckmann, J.M.21
Soltermann, A.22
Moch, H.23
Koker, M.24
Leenders, F.25
Gabler, F.26
Querings, S.27
Ansén, S.28
Brambilla, E.29
Brambilla, C.30
Lorimier, P.31
Brustugun, O.T.32
Helland, A.33
Petersen, I.34
Clement, J.H.35
Groen, H.36
Timens, W.37
Sietsma, H.38
Stoelben, E.39
Wolf, J.40
Beer, D.G.41
Tsao, M.S.42
Hanna, M.43
Hatton, C.44
Eck, M.J.45
Janne, P.A.46
Johnson, B.E.47
Winckler, W.48
Greulich, H.49
Bass, A.J.50
Cho, J.51
more..
-
33
-
-
33746831573
-
The discoidin domain receptor DDR2 is a receptor for type X collagen
-
Leitinger, B., and Kwan, A. P. (2006) The discoidin domain receptor DDR2 is a receptor for type X collagen. Matrix Biol. 25, 355-364
-
(2006)
Matrix Biol
, vol.25
, pp. 355-364
-
-
Leitinger, B.1
Kwan, A.P.2
-
34
-
-
42449113812
-
Cell-collagen interactions: The use of peptide Toolkits to investigate collagen-receptor interactions
-
Farndale, R. W., Lisman, T., Bihan, D., Hamaia, S., Smerling, C. S., Pugh, N., Konitsiotis, A., Leitinger, B., de Groot, P. G., Jarvis, G. E., and Raynal, N. (2008) Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions. Biochem. Soc. Trans. 36, 241-250
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 241-250
-
-
Farndale, R.W.1
Lisman, T.2
Bihan, D.3
Hamaia, S.4
Smerling, C.S.5
Pugh, N.6
Konitsiotis, A.7
Leitinger, B.8
De Groot, P.G.9
Jarvis, G.E.10
Raynal, N.11
-
35
-
-
79251579592
-
Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
-
Gu, T. L., Deng, X., Huang, F., Tucker, M., Crosby, K., Rimkunas, V., Wang, Y., Deng, G., Zhu, L., Tan, Z., Hu, Y., Wu, C., Nardone, J., MacNeill, J., Ren, J., Reeves, C., Innocenti, G., Norris, B., Yuan, J., Yu, J., Haack, H., Shen, B., Peng, C., Li, H., Zhou, X., Liu, X., Rush, J., and Comb, M. J. (2011) Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma. PLoS ONE 6, e15640
-
(2011)
PLoS ONE
, vol.6
-
-
Gu, T.L.1
Deng, X.2
Huang, F.3
Tucker, M.4
Crosby, K.5
Rimkunas, V.6
Wang, Y.7
Deng, G.8
Zhu, L.9
Tan, Z.10
Hu, Y.11
Wu, C.12
Nardone, J.13
MacNeill, J.14
Ren, J.15
Reeves, C.16
Innocenti, G.17
Norris, B.18
Yuan, J.19
Yu, J.20
Haack, H.21
Shen, B.22
Peng, C.23
Li, H.24
Zhou, X.25
Liu, X.26
Rush, J.27
Comb, M.J.28
more..
-
36
-
-
50349096759
-
Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens
-
Giudici, C., Raynal, N., Wiedemann, H., Cabral, W. A., Marini, J. C., Timpl, R., Bächinger, H. P., Farndale, R. W., Sasaki, T., and Tenni, R. (2008) Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens. J. Biol. Chem. 283, 19551-19560
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19551-19560
-
-
Giudici, C.1
Raynal, N.2
Wiedemann, H.3
Cabral, W.A.4
Marini, J.C.5
Timpl, R.6
Bächinger, H.P.7
Farndale, R.W.8
Sasaki, T.9
Tenni, R.10
-
37
-
-
79551505872
-
Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes
-
Parkin, J. D., San Antonio, J. D., Pedchenko, V., Hudson, B., Jensen, S. T., and Savige, J. (2011) Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes. Hum. Mutat. 32, 127-143
-
(2011)
Hum. Mutat.
, vol.32
, pp. 127-143
-
-
Parkin, J.D.1
San Antonio, J.D.2
Pedchenko, V.3
Hudson, B.4
Jensen, S.T.5
Savige, J.6
-
38
-
-
70349859994
-
The relative roles of collagen adhesive receptor DDR2 activation and matrix stiffness in the down-regulation of focal adhesion kinase in vascular smooth muscle cells
-
Bhadriraju, K., Chung, K. H., Spurlin, T. A., Haynes, R. J., Elliott, J. T., and Plant, A. L. (2009) The relative roles of collagen adhesive receptor DDR2 activation and matrix stiffness in the down-regulation of focal adhesion kinase in vascular smooth muscle cells. Biomaterials 30, 6687-6694
-
(2009)
Biomaterials
, vol.30
, pp. 6687-6694
-
-
Bhadriraju, K.1
Chung, K.H.2
Spurlin, T.A.3
Haynes, R.J.4
Elliott, J.T.5
Plant, A.L.6
-
39
-
-
14744294813
-
Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development
-
Ith, B., Wei, J., Yet, S. F., Perrella, M. A., and Layne, M. D. (2005) Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development. Gene Expr. Patterns 5, 533-537
-
(2005)
Gene Expr. Patterns
, vol.5
, pp. 533-537
-
-
Ith, B.1
Wei, J.2
Yet, S.F.3
Perrella, M.A.4
Layne, M.D.5
-
40
-
-
0037125948
-
Binding of discoidin domain receptor 2 to collagen I: An atomic force microscopy investigation
-
Agarwal, G., Kovac, L., Radziejewski, C., and Samuelsson, S. J. (2002) Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation. Biochemistry 41, 11091-11098
-
(2002)
Biochemistry
, vol.41
, pp. 11091-11098
-
-
Agarwal, G.1
Kovac, L.2
Radziejewski, C.3
Samuelsson, S.J.4
-
41
-
-
33847122893
-
Interaction of discoidin domain receptor 1 with collagen type 1
-
Agarwal, G., Mihai, C., and Iscru, D. F. (2007) Interaction of discoidin domain receptor 1 with collagen type 1. J. Mol. Biol. 367, 443-455
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 443-455
-
-
Agarwal, G.1
Mihai, C.2
Iscru, D.F.3
-
42
-
-
1942469341
-
Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: Potential implications in atherosclerosis and lymphangioleiomyomatosis
-
Ferri, N., Carragher, N. O., and Raines, E. W. (2004) Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. Am. J. Pathol. 164, 1575-1585
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1575-1585
-
-
Ferri, N.1
Carragher, N.O.2
Raines, E.W.3
-
43
-
-
28844477778
-
Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen
-
Wall, S. J., Werner, E., Werb, Z., and DeClerck, Y. A. (2005) Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen. J. Biol. Chem. 280, 40187-40194
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40187-40194
-
-
Wall, S.J.1
Werner, E.2
Werb, Z.3
Declerck, Y.A.4
-
44
-
-
0035085253
-
Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development
-
Vogel, W. F., Aszódi, A., Alves, F., and Pawson, T. (2001) Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development. Mol. Cell. Biol. 21, 2906-2917
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2906-2917
-
-
Vogel, W.F.1
Aszódi, A.2
Alves, F.3
Pawson, T.4
-
45
-
-
0034988084
-
The collagen receptor DDR2 regulates proliferation, and its elimination leads to dwarfism
-
Labrador, J. P., Azcoitia, V., Tuckermann, J., Lin, C., Olaso, E., Mañes, S., Brückner, K., Goergen, J. L., Lemke, G., Yancopoulos, G., Angel, P., Martínez, C., and Klein, R. (2001) The collagen receptor DDR2 regulates proliferation, and its elimination leads to dwarfism. EMBO Rep. 2, 446-452
-
(2001)
EMBO Rep
, vol.2
, pp. 446-452
-
-
Labrador, J.P.1
Azcoitia, V.2
Tuckermann, J.3
Lin, C.4
Olaso, E.5
Mañes, S.6
Brückner, K.7
Goergen, J.L.8
Lemke, G.9
Yancopoulos, G.10
Angel, P.11
Martínez, C.12
Klein, R.13
-
46
-
-
73449140118
-
Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice
-
Kano, K., Kitamura, A., Matsuwaki, T., Morimatsu, M., and Naito, K. (2010) Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice. Mol. Reprod. Dev. 77, 29-37
-
(2010)
Mol. Reprod. Dev.
, vol.77
, pp. 29-37
-
-
Kano, K.1
Kitamura, A.2
Matsuwaki, T.3
Morimatsu, M.4
Naito, K.5
-
47
-
-
48249091732
-
A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse
-
Kano, K., Marín de Evsikova, C., Young, J., Wnek, C., Maddatu, T. P., Nishina, P. M., and Naggert, J. K. (2008) A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Mol. Endocrinol. 22, 1866-1880
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1866-1880
-
-
Kano, K.1
Marín De Evsikova, C.2
Young, J.3
Wnek, C.4
Maddatu, T.P.5
Nishina, P.M.6
Naggert, J.K.7
-
48
-
-
34249678458
-
Quantitative proteomic assessment of very early cellular signaling events
-
Dengjel, J., Akimov, V., Olsen, J. V., Bunkenborg, J., Mann, M., Blagoev, B., and Andersen, J. S. (2007) Quantitative proteomic assessment of very early cellular signaling events. Nat. Biotechnol. 25, 566-568
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 566-568
-
-
Dengjel, J.1
Akimov, V.2
Olsen, J.V.3
Bunkenborg, J.4
Mann, M.5
Blagoev, B.6
Andersen, J.S.7
-
49
-
-
33344455174
-
Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction
-
Furdui, C. M., Lew, E. D., Schlessinger, J., and Anderson, K. S. (2006) Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction. Mol. Cell 21, 711-717
-
(2006)
Mol. Cell
, vol.21
, pp. 711-717
-
-
Furdui, C.M.1
Lew, E.D.2
Schlessinger, J.3
Anderson, K.S.4
-
50
-
-
78951489049
-
Feedback regulation of EGFR signalling: Decision making by early and delayed loops
-
Avraham, R., and Yarden, Y. (2011) Feedback regulation of EGFR signalling: decision making by early and delayed loops. Nat. Rev. Mol. Cell Biol. 12, 104-117
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 104-117
-
-
Avraham, R.1
Yarden, Y.2
-
51
-
-
33847292778
-
From Tpr-Met to Met, tumorigenesis and tubes
-
Peschard, P., and Park, M. (2007) From Tpr-Met to Met, tumorigenesis and tubes. Oncogene 26, 1276-1285
-
(2007)
Oncogene
, vol.26
, pp. 1276-1285
-
-
Peschard, P.1
Park, M.2
-
52
-
-
34047174559
-
A module of negative feedback regulators defines growth factor signaling
-
Amit, I., Citri, A., Shay, T., Lu, Y., Katz, M., Zhang, F., Tarcic, G., Siwak, D., Lahad, J., Jacob-Hirsch, J., Amariglio, N., Vaisman, N., Segal, E., Rechavi, G., Alon, U., Mills, G. B., Domany, E., and Yarden, Y. (2007) A module of negative feedback regulators defines growth factor signaling. Nat. Genet. 39, 503-512
-
(2007)
Nat. Genet.
, vol.39
, pp. 503-512
-
-
Amit, I.1
Citri, A.2
Shay, T.3
Lu, Y.4
Katz, M.5
Zhang, F.6
Tarcic, G.7
Siwak, D.8
Lahad, J.9
Jacob-Hirsch, J.10
Amariglio, N.11
Vaisman, N.12
Segal, E.13
Rechavi, G.14
Alon, U.15
Mills, G.B.16
Domany, E.17
Yarden, Y.18
-
53
-
-
33744764925
-
A discoidin domain receptor 1/SHP-2 signaling complex inhibits α2β1-integrin- mediated signal transducers and activators of transcription 1/3 activation and cell migration
-
Wang, C. Z., Su, H. W., Hsu, Y. C., Shen, M. R., and Tang, M. J. (2006) A discoidin domain receptor 1/SHP-2 signaling complex inhibits α2β1-integrin- mediated signal transducers and activators of transcription 1/3 activation and cell migration. Mol. Biol. Cell 17, 2839-2852
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2839-2852
-
-
Wang, C.Z.1
Su, H.W.2
Hsu, Y.C.3
Shen, M.R.4
Tang, M.J.5
-
54
-
-
68849099260
-
DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading
-
Wang, C. Z., Yeh, Y. C., and Tang, M. J. (2009) DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading. Am. J. Physiol. Cell Physiol. 297, C419-C429
-
(2009)
Am. J. Physiol. Cell Physiol.
, vol.297
-
-
Wang, C.Z.1
Yeh, Y.C.2
Tang, M.J.3
-
55
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
56
-
-
33847355217
-
Growth factorinduced MAPK network topology shapes Erk response determining PC-12 cell fate
-
Santos, S. D., Verveer, P. J., and Bastiaens, P. I. (2007) Growth factorinduced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat. Cell Biol. 9, 324-330
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 324-330
-
-
Santos, S.D.1
Verveer, P.J.2
Bastiaens, P.I.3
-
57
-
-
0034015551
-
Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: Activation of juxtamembrane domains in PDGFR/ DDR/TrkA chimeric receptors
-
Foehr, E. D., Tatavos, A., Tanabe, E., Raffioni, S., Goetz, S., Dimarco, E., De Luca, M., and Bradshaw, R. A. (2000) Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/ DDR/TrkA chimeric receptors. FASEB J. 14, 973-981
-
(2000)
FASEB J
, vol.14
, pp. 973-981
-
-
Foehr, E.D.1
Tatavos, A.2
Tanabe, E.3
Raffioni, S.4
Goetz, S.5
Dimarco, E.6
De Luca, M.7
Bradshaw, R.A.8
-
58
-
-
80055062698
-
Integrin-linked kinase: Not so 'pseudo' after all
-
Hannigan, G. E., McDonald, P. C., Walsh, M. P., and Dedhar, S. (2011) Integrin-linked kinase: not so 'pseudo' after all. Oncogene 30, 4375-4385
-
(2011)
Oncogene
, vol.30
, pp. 4375-4385
-
-
Hannigan, G.E.1
McDonald, P.C.2
Walsh, M.P.3
Dedhar, S.4
-
59
-
-
84859075498
-
The role of pseudokinases in cancer
-
Zhang, H., Photiou, A., Grothey, A., Stebbing, J., and Giamas, G. (2012) The role of pseudokinases in cancer. Cell. Signal. 24, 1173-1184
-
(2012)
Cell. Signal.
, vol.24
, pp. 1173-1184
-
-
Zhang, H.1
Photiou, A.2
Grothey, A.3
Stebbing, J.4
Giamas, G.5
-
60
-
-
78650512223
-
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
-
Hidalgo-Carcedo, C., Hooper, S., Chaudhry, S. I., Williamson, P., Harrington, K., Leitinger, B., and Sahai, E. (2011) Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat. Cell Biol. 13, 49-58
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 49-58
-
-
Hidalgo-Carcedo, C.1
Hooper, S.2
Chaudhry, S.I.3
Williamson, P.4
Harrington, K.5
Leitinger, B.6
Sahai, E.7
-
61
-
-
58549118075
-
Linear combinations of docking affinities explain quantitative differences in RTK signaling
-
Gordus, A., Krall, J. A., Beyer, E. M., Kaushansky, A., Wolf-Yadlin, A., Sevecka, M., Chang, B. H., Rush, J., and MacBeath, G. (2009) Linear combinations of docking affinities explain quantitative differences in RTK signaling. Mol. Syst. Biol. 5, 235
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 235
-
-
Gordus, A.1
Krall, J.A.2
Beyer, E.M.3
Kaushansky, A.4
Wolf-Yadlin, A.5
Sevecka, M.6
Chang, B.H.7
Rush, J.8
MacBeath, G.9
-
62
-
-
84862232059
-
Phosphotyrosine-mediated protein interactions of the discoidin domain receptor 1
-
Lemeer, S., Bluwstein, A., Wu, Z., Leberfinger, J., Müller, K., Kramer, K., and Kuster, B. (2012) Phosphotyrosine-mediated protein interactions of the discoidin domain receptor 1. J. Proteomics 75, 3465-3477
-
(2012)
J. Proteomics
, vol.75
, pp. 3465-3477
-
-
Lemeer, S.1
Bluwstein, A.2
Wu, Z.3
Leberfinger, J.4
Müller, K.5
Kramer, K.6
Kuster, B.7
-
63
-
-
67649889124
-
Differential effects of EGFR ligands on endocytic sorting of the receptor
-
Roepstorff, K., Grandal, M. V., Henriksen, L., Knudsen, S. L., Lerdrup, M., Grøvdal, L., Willumsen, B. M., and van Deurs, B. (2009) Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic 10, 1115-1127
-
(2009)
Traffic
, vol.10
, pp. 1115-1127
-
-
Roepstorff, K.1
Grandal, M.V.2
Henriksen, L.3
Knudsen, S.L.4
Lerdrup, M.5
Grøvdal, L.6
Willumsen, B.M.7
Van Deurs, B.8
-
64
-
-
63049100044
-
Functional selectivity of EGF family peptide growth factors: Implications for cancer
-
Wilson, K. J., Gilmore, J. L., Foley, J., Lemmon, M. A., and Riese, D. J., 2nd (2009) Functional selectivity of EGF family peptide growth factors: implications for cancer. Pharmacol. Ther. 122, 1-8
-
(2009)
Pharmacol. Ther.
, vol.122
, pp. 1-8
-
-
Wilson, K.J.1
Gilmore, J.L.2
Foley, J.3
Lemmon, M.A.4
Riese II, D.J.5
-
65
-
-
66149149720
-
Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases
-
Abella, J. V., and Park, M. (2009) Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases. Am. J. Physiol. Endocrinol Metab. 296, E973-E984
-
(2009)
Am. J. Physiol. Endocrinol Metab.
, vol.296
-
-
Abella, J.V.1
Park, M.2
-
66
-
-
58149096469
-
Mapping of DDR1 distribution and oligomerization on the cell surface by FRET microscopy
-
Mihai, C., Chotani, M., Elton, T. S., and Agarwal, G. (2009) Mapping of DDR1 distribution and oligomerization on the cell surface by FRET microscopy. J. Mol. Biol. 385, 432-445
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 432-445
-
-
Mihai, C.1
Chotani, M.2
Elton, T.S.3
Agarwal, G.4
-
67
-
-
70449552889
-
Endosomes: A legitimate platform for the signaling train
-
Murphy, J. E., Padilla, B. E., Hasdemir, B., Cottrell, G. S., and Bunnett, N. W. (2009) Endosomes: a legitimate platform for the signaling train. Proc. Natl. Acad. Sci. U.S.A. 106, 17615-17622
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
68
-
-
80053321997
-
Mechanisms of integrin activation and trafficking
-
Margadant, C., Monsuur, H. N., Norman, J. C., and Sonnenberg, A. (2011) Mechanisms of integrin activation and trafficking. Curr. Opin. Cell Biol. 23, 607-614
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 607-614
-
-
Margadant, C.1
Monsuur, H.N.2
Norman, J.C.3
Sonnenberg, A.4
-
69
-
-
84867728445
-
Numb/Numbl-opo antagonism controls retinal epithelium morphogenesis by regulating integrin endocytosis
-
Bogdanović, O., Delfino-Machín, M., Nicolás- Pérez, M., Gavilán, M. P., Gago-Rodrigues, I., Fernández-Miñán, A., Lillo, C., Ríos, R. M., Wittbrodt, J., and Martínez-Morales, J. R. (2012) Numb/Numbl-opo antagonism controls retinal epithelium morphogenesis by regulating integrin endocytosis. Dev. Cell 23, 782-795
-
(2012)
Dev. Cell
, vol.23
, pp. 782-795
-
-
Bogdanović, O.1
Delfino-Machín, M.2
Nicolás-Pérez, M.3
Gavilán, M.P.4
Gago-Rodrigues, I.5
Fernández-Miñán, A.6
Lillo, C.7
Ríos, R.M.8
Wittbrodt, J.9
Martínez-Morales, J.R.10
-
70
-
-
77953151717
-
Molecular and cellular mechanisms of ectodomain shedding
-
Hayashida, K., Bartlett, A. H., Chen, Y., and Park, P. W. (2010) Molecular and cellular mechanisms of ectodomain shedding. Anat. Rec. 293, 925-937
-
(2010)
Anat. Rec.
, vol.293
, pp. 925-937
-
-
Hayashida, K.1
Bartlett, A.H.2
Chen, Y.3
Park, P.W.4
-
71
-
-
0036840511
-
Discoidin domain receptor 1 controls growth and adhesion of mesangial cells
-
Curat, C. A., and Vogel, W. F. (2002) Discoidin domain receptor 1 controls growth and adhesion of mesangial cells. J. Am. Soc. Nephrol. 13, 2648-2656
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2648-2656
-
-
Curat, C.A.1
Vogel, W.F.2
-
72
-
-
73249126900
-
Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2
-
Flynn, L. A., Blissett, A. R., Calomeni, E. P., and Agarwal, G. (2010) Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2. J. Mol. Biol. 395, 533-543
-
(2010)
J. Mol. Biol.
, vol.395
, pp. 533-543
-
-
Flynn, L.A.1
Blissett, A.R.2
Calomeni, E.P.3
Agarwal, G.4
-
73
-
-
77951975626
-
The influence of discoidin domain receptor 2 on the persistence length of collagen type i fibers
-
Sivakumar, L., and Agarwal, G. (2010) The influence of discoidin domain receptor 2 on the persistence length of collagen type I fibers. Biomaterials 31, 4802-4808
-
(2010)
Biomaterials
, vol.31
, pp. 4802-4808
-
-
Sivakumar, L.1
Agarwal, G.2
-
74
-
-
70350233406
-
Navigating ECM barriers at the invasive front: The cancer cell-stroma interface
-
Rowe, R. G., and Weiss, S. J. (2009) Navigating ECM barriers at the invasive front: the cancer cell-stroma interface. Annu. Rev. Cell Dev. Biol. 25, 567-595
-
(2009)
Annu. Rev. Cell Dev. Biol.
, vol.25
, pp. 567-595
-
-
Rowe, R.G.1
Weiss, S.J.2
-
75
-
-
0036480050
-
Functional analysis of discoidin domain receptor 1: Effect of adhesion on DDR1 phosphorylation
-
L'hôte, C. G., Thomas, P. H., and Ganesan, T. S. (2002) Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation. FASEB J. 16, 234-236
-
(2002)
FASEB J.
, vol.16
, pp. 234-236
-
-
L'Hôte, C.G.1
Thomas, P.H.2
Ganesan, T.S.3
-
76
-
-
0037454766
-
Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion
-
Dejmek, J., Dib, K., Jönsson, M., and Andersson, T. (2003) Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion. Int. J. Cancer 103, 344-351
-
(2003)
Int. J. Cancer
, vol.103
, pp. 344-351
-
-
Dejmek, J.1
Dib, K.2
Jönsson, M.3
Andersson, T.4
-
77
-
-
29344437297
-
Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1
-
Koo, D. H., McFadden, C., Huang, Y., Abdulhussein, R., Friese-Hamim, M., and Vogel, W. F. (2006) Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1. FEBS Lett. 580, 15-22
-
(2006)
FEBS Lett
, vol.580
, pp. 15-22
-
-
Koo, D.H.1
McFadden, C.2
Huang, Y.3
Abdulhussein, R.4
Friese-Hamim, M.5
Vogel, W.F.6
-
78
-
-
70350458156
-
Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins
-
Yang, G., Li, Q., Ren, S., Lu, X., Fang, L., Zhou, W., Zhang, F., Xu, F., Zhang, Z., Zeng, R., Lottspeich, F., and Chen, Z. (2009) Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins. Proteomics 9, 4944-4961
-
(2009)
Proteomics
, vol.9
, pp. 4944-4961
-
-
Yang, G.1
Li, Q.2
Ren, S.3
Lu, X.4
Fang, L.5
Zhou, W.6
Zhang, F.7
Xu, F.8
Zhang, Z.9
Zeng, R.10
Lottspeich, F.11
Chen, Z.12
-
79
-
-
79551610201
-
Collagen stimulates discoidin domain receptor 1-mediated migration of smooth muscle cells through Src
-
Lu, K. K., Trcka, D., and Bendeck, M. P. (2011) Collagen stimulates discoidin domain receptor 1-mediated migration of smooth muscle cells through Src. Cardiovasc. Pathol. 20, 71-76
-
(2011)
Cardiovasc. Pathol.
, vol.20
, pp. 71-76
-
-
Lu, K.K.1
Trcka, D.2
Bendeck, M.P.3
-
80
-
-
80051544191
-
Collagen i regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1
-
Suh, H. N., and Han, H. J. (2011) Collagen I regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1. J. Cell. Phyisiol. 226, 3422-3432
-
(2011)
J. Cell. Phyisiol.
, vol.226
, pp. 3422-3432
-
-
Suh, H.N.1
Han, H.J.2
-
81
-
-
0344837350
-
P53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop
-
Ongusaha, P. P., Kim, J. I., Fang, L., Wong, T. W., Yancopoulos, G. D., Aaronson, S. A., and Lee, S. W. (2003) p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop. EMBO J. 22, 1289-1301
-
(2003)
EMBO J
, vol.22
, pp. 1289-1301
-
-
Ongusaha, P.P.1
Kim, J.I.2
Fang, L.3
Wong, T.W.4
Yancopoulos, G.D.5
Aaronson, S.A.6
Lee, S.W.7
-
82
-
-
0037166277
-
Discoidin domain receptor 2 interacts with Src and Shc following its activation by type i collagen
-
Ikeda, K., Wang, L. H., Torres, R., Zhao, H., Olaso, E., Eng, F. J., Labrador, P., Klein, R., Lovett, D., Yancopoulos, G. D., Friedman, S. L., and Lin, H. C. (2002) Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen. J. Biol. Chem. 277, 19206-19212
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19206-19212
-
-
Ikeda, K.1
Wang, L.H.2
Torres, R.3
Zhao, H.4
Olaso, E.5
Eng, F.J.6
Labrador, P.7
Klein, R.8
Lovett, D.9
Yancopoulos, G.D.10
Friedman, S.L.11
Lin, H.C.12
-
83
-
-
79951830551
-
Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling
-
Olaso, E., Lin, H. C., Wang, L. H., and Friedman, S. L. (2011) Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling. Fibrogenesis Tissue Repair 4, 5
-
Fibrogenesis Tissue Repair
, vol.4
, Issue.2011
, pp. 5
-
-
Olaso, E.1
Lin, H.C.2
Wang, L.H.3
Friedman, S.L.4
-
84
-
-
28244437005
-
Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation
-
Yang, K., Kim, J. H., Kim, H. J., Park, I. S., Kim, I. Y., and Yang, B. S. (2005) Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation. J. Biol. Chem. 280, 39058-39066
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39058-39066
-
-
Yang, K.1
Kim, J.H.2
Kim, H.J.3
Park, I.S.4
Kim, I.Y.5
Yang, B.S.6
-
85
-
-
51049121850
-
Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates
-
Sweeney, S. M., Orgel, J. P., Fertala, A., McAuliffe, J. D., Turner, K. R., Di Lullo, G. A., Chen, S., Antipova, O., Perumal, S., Ala-Kokko, L., Forlino, A., Cabral, W. A., Barnes, A. M., Marini, J. C., and San Antonio, J. D. (2008) Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates. J. Biol. Chem. 283, 21187-21197
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21187-21197
-
-
Sweeney, S.M.1
Orgel, J.P.2
Fertala, A.3
McAuliffe, J.D.4
Turner, K.R.5
Di Lullo, G.A.6
Chen, S.7
Antipova, O.8
Perumal, S.9
Ala Kokko, L.10
Forlino, A.11
Cabral, W.A.12
Barnes, A.M.13
Marini, J.C.14
San Antonio, J.D.15
-
86
-
-
41549155540
-
Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1
-
Shintani, Y., Fukumoto, Y., Chaika, N., Svoboda, R., Wheelock, M. J., and Johnson, K. R. (2008) Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1. J. Cell Biol. 180, 1277-1289
-
(2008)
J. Cell Biol.
, vol.180
, pp. 1277-1289
-
-
Shintani, Y.1
Fukumoto, Y.2
Chaika, N.3
Svoboda, R.4
Wheelock, M.J.5
Johnson, K.R.6
-
87
-
-
58149142702
-
Discoidin domain receptor 1 activation suppresses α2β1 integrin-dependent cell spreading through inhibition of Cdc42 activity
-
Yeh, Y. C., Wang, C. Z., and Tang, M. J. (2009) Discoidin domain receptor 1 activation suppresses α2β1 integrin-dependent cell spreading through inhibition of Cdc42 activity. J. Cell. Physiol. 218, 146-156
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 146-156
-
-
Yeh, Y.C.1
Wang, C.Z.2
Tang, M.J.3
-
88
-
-
84871457764
-
Discoidin domain receptors promote α1β1- and α2β1-integrinmediated cell adhesion to collagen by enhancing integrin activation
-
Xu, H., Bihan, D., Chang, F., Huang, P. H., Farndale, R. W., and Leitinger, B. (2012) Discoidin domain receptors promote α1β1- and α2β1-integrinmediated cell adhesion to collagen by enhancing integrin activation. PLoS ONE 7, e52209
-
(2012)
PLoS ONE
, vol.7
-
-
Xu, H.1
Bihan, D.2
Chang, F.3
Huang, P.H.4
Farndale, R.W.5
Leitinger, B.6
-
89
-
-
0034960540
-
Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells
-
Jönsson, M., and Andersson, T. (2001) Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells. J. Cell Sci. 114, 2043-2053
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2043-2053
-
-
Jönsson, M.1
Andersson, T.2
-
90
-
-
36549025433
-
Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth
-
Roarty, K., and Serra, R. (2007) Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth. Development 134, 3929-3939
-
(2007)
Development
, vol.134
, pp. 3929-3939
-
-
Roarty, K.1
Serra, R.2
-
91
-
-
79955968796
-
DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation
-
Kim, H. G., Hwang, S. Y., Aaronson, S. A., Mandinova, A., and Lee, S. W. (2011) DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation. J. Biol. Chem. 286, 17672-17681
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17672-17681
-
-
Kim, H.G.1
Hwang, S.Y.2
Aaronson, S.A.3
Mandinova, A.4
Lee, S.W.5
-
92
-
-
84878788785
-
Phosphoproteomic analysis identifies insulin enhancement of discoidin domain receptor 2 phosphorylation
-
Iwai, L. K., Chang, F., and Huang, P. H. (2013) Phosphoproteomic analysis identifies insulin enhancement of discoidin domain receptor 2 phosphorylation. Cell Adh. Migr. 7, 1-4
-
(2013)
Cell Adh. Migr.
, vol.7
, pp. 1-4
-
-
Iwai, L.K.1
Chang, F.2
Huang, P.H.3
-
93
-
-
84858028202
-
Phosphoproteomic studies of receptor tyrosine kinases: Future perspectives
-
Huang, P. H. (2012) Phosphoproteomic studies of receptor tyrosine kinases: future perspectives. Mol. Biosyst. 8, 1100-1107
-
(2012)
Mol. Biosyst.
, vol.8
, pp. 1100-1107
-
-
Huang, P.H.1
-
94
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network (2012) Comprehensive molecular portraits of human breast tumours. Nature 490, 61-70
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
|