Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives

European Journal of Medicinal Chemistry

Volumn 95, Issue , 2015, Pages 49-63

  Ramprasad, Jurupula ^a   Nayak, Nagabhushana ^a   Dalimba, Udayakumar ^a   Yogeeswari, Perumal ^b   Sriram, Dharmarajan ^b   Peethambar, S K ^c   Achur, Rajeshwara ^c   Kumar, H S Santosh ^c  

^a NATIONAL INSTITUTE OF TECHNOLOGY KARNATAKA   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^c KUVEMPU UNIVERSITY   (India)

Author keywords

Antibacterial agent; Antioxidant activity; Benzimidazole; Cytotoxicity; Imidazo 2,1 b 1,3,4 thiadiazole; Mycobacterium tuberculosis

Indexed keywords

2 (IMIDAZO[2,1 B ] [1,3,4]THIADIAZOL 5 YL) 1H BENZIMIDAZOLE DERIVATIVE; 2 [2 METHYL 6 (4 METHYL PHENYL) IMIDAZO[2,1 B ][1,3,4]THIADIAZOL 5 YL] 1H BENZIMIDAZOLE; 6 (4 METHOXYPHENYL) 2 (4 METHYLPHENYL)IMIDAZO[2,1 B[1,3,4]THIADIAZOLE 5 CARBALDEHYDE; BENZIMIDAZOLE DERIVATIVE; BUTYLCRESOL; FLUCONAZOLE; STREPTOMYCIN; UNCLASSIFIED DRUG; 2-(2-METHYL-6-(4-METHYL PHENYL)IMIDAZO(2,1-B)(1,3,4)THIADIAZOL-5-YL)-1H-BENZIMIDAZOLE; 5-CHLORO-2-(6-(4-FLUOROPHENYL)-2-METHYLIMIDAZO(2,1-B)(1,3,4)THIADIAZOL-5-YL)-1H-BENZO(D)IMIDAZOLE; ANTIFUNGAL AGENT; ANTIOXIDANT; BENZIMIDAZOLE; THIADIAZOLE DERIVATIVE; TUBERCULOSTATIC AGENT;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; ANIMAL; CELL SURVIVAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; EVALUATION STUDY; GROWTH, DEVELOPMENT AND AGING; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUBERCULOSIS; VERO CELL LINE;

ANIMALS; ANTIFUNGAL AGENTS; ANTIOXIDANTS; ANTITUBERCULAR AGENTS; BENZIMIDAZOLES; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; TUBERCULOSIS; VERO CELLS;

EID: 84924855172     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.03.024     Document Type: Article

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