Synthesis, spectral studies and biological evaluation of a novel series of 2-substituted-5,6-diarylsubstituted imidazo(2,1-b)-1,3, 4-thiadiazole derivatives as possible anti-tubercular agents

Medicinal Chemistry Research

Volumn 21, Issue 7, 2012, Pages 1313-1321

  Palkar, Mahesh B ^a   Noolvi, Malleshappa N ^b   Maddi, Veeresh S ^a   Ghatole, Mangala ^c   Nargund, Laxmivenkat G ^d  

^a KLE College of Pharmacy   (India)

^b Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy   (India)

^c Dr Vaishampayan Memorial Medical College   (India)

^d Nargund College of Pharmacy   (India)

Author keywords

2 Amino 5 substituted 1,3,4 thiadiazoles; Anti tubercular activity; Cytotoxicity; Imidazo (2,1 b) 1,3,4 thiadiazoles

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; GATIFLOXACIN; IMIDAZOLE DERIVATIVE; ISONIAZID; KETONE DERIVATIVE; TUBERCULOSTATIC AGENT;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; IC 50; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; VERO CELL;

EID: 84861853702     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9646-9     Document Type: Article

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