메뉴 건너뛰기




Volumn 45, Issue 3, 2015, Pages 679-686

NSAIDs: Learning new tricks from old drugs

Author keywords

L selectin; NADPH oxidase; Non steroidal anti inflammatory drugs

Indexed keywords

L SELECTIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

EID: 84924580262     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445222     Document Type: Article
Times cited : (88)

References (73)
  • 1
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
    • Warner, T. D., Giuliano, F., Vojnovic, I., Bukasa, A., Mitchell, J. A. and Vane, J. R., Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. USA 1999. 96: 7563-7568.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6
  • 2
    • 77953592687 scopus 로고    scopus 로고
    • Diclofenac: an update on its mechanism of action and safety profile
    • Gan, T. J., Diclofenac: an update on its mechanism of action and safety profile. Curr. Med. Res. Opin. 2010. 26: 1715-1731.
    • (2010) Curr. Med. Res. Opin. , vol.26 , pp. 1715-1731
    • Gan, T.J.1
  • 3
    • 84883616305 scopus 로고    scopus 로고
    • Interaction of nonsteroidal anti-inflammatory drugs with membranes: in vitro assessment and relevance for their biological actions
    • Pereira-Leite, C., Nunes, C. and Reis, S., Interaction of nonsteroidal anti-inflammatory drugs with membranes: in vitro assessment and relevance for their biological actions. Prog. Lipid Res. 2013. 52: 571-584.
    • (2013) Prog. Lipid Res. , vol.52 , pp. 571-584
    • Pereira-Leite, C.1    Nunes, C.2    Reis, S.3
  • 4
    • 84903420055 scopus 로고    scopus 로고
    • The influence of cholesterol on interactions and dynamics of ibuprofen in a lipid bilayer
    • Khajeh, A. and Modarress, H., The influence of cholesterol on interactions and dynamics of ibuprofen in a lipid bilayer. Biochim. Biophys. Acta 2014. 1838: 2431-2438.
    • (2014) Biochim. Biophys. Acta , vol.1838 , pp. 2431-2438
    • Khajeh, A.1    Modarress, H.2
  • 5
    • 0028916230 scopus 로고
    • Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs
    • Diaz-Gonzalez, F., Gonzalez-Alvaro, I., Campanero, M. R., Mollinedo, F., del Pozo, M. A., Munoz, C., Pivel, J. P. et al., Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs. J.Clin. Invest. 1995. 95: 1756-1765.
    • (1995) J.Clin. Invest. , vol.95 , pp. 1756-1765
    • Diaz-Gonzalez, F.1    Gonzalez-Alvaro, I.2    Campanero, M.R.3    Mollinedo, F.4    del Pozo, M.A.5    Munoz, C.6    Pivel, J.P.7
  • 6
    • 84904397295 scopus 로고    scopus 로고
    • A novel COX-independent mechanism of sulindac sulfide involves cleavage of epithelial cell adhesion molecule protein
    • Liggett, J. L., Min, K. W., Smolensky, D. and Baek, S. J., A novel COX-independent mechanism of sulindac sulfide involves cleavage of epithelial cell adhesion molecule protein. Exp. Cell Res. 2014. 326: 1-9.
    • (2014) Exp. Cell Res. , vol.326 , pp. 1-9
    • Liggett, J.L.1    Min, K.W.2    Smolensky, D.3    Baek, S.J.4
  • 8
    • 84872453673 scopus 로고    scopus 로고
    • L-selectin shedding by NSAIDs: old friends in new dresses
    • Zarbock, A. and Rossaint, J., L-selectin shedding by NSAIDs: old friends in new dresses. Eur. J. Immunol. 2013. 43: 50-54.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 50-54
    • Zarbock, A.1    Rossaint, J.2
  • 10
    • 0037064135 scopus 로고    scopus 로고
    • Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs
    • Gomez-Gaviro, M. V., Gonzalez-Alvaro, I., Dominguez-Jimenez, C., Peschon, J., Black, R. A., Sanchez-Madrid, F. and Diaz-Gonzalez, F., Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. J. Biol. Chem. 2002. 277: 38212-38221.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38212-38221
    • Gomez-Gaviro, M.V.1    Gonzalez-Alvaro, I.2    Dominguez-Jimenez, C.3    Peschon, J.4    Black, R.A.5    Sanchez-Madrid, F.6    Diaz-Gonzalez, F.7
  • 14
    • 77954888689 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and brain inflammation: Effects on microglial functions
    • Ajmone-Cat, M. A., Bernardo, A., Greco, A. and Minghetti, L., Non-steroidal anti-inflammatory drugs and brain inflammation: Effects on microglial functions. Pharmaceuticals 2010. 3: 1949-1964.
    • (2010) Pharmaceuticals , vol.3 , pp. 1949-1964
    • Ajmone-Cat, M.A.1    Bernardo, A.2    Greco, A.3    Minghetti, L.4
  • 15
    • 34748896047 scopus 로고    scopus 로고
    • NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development?
    • Weggen, S., Rogers, M. and Eriksen, J., NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? Trends Pharmacol. Sci. 2007. 28: 536-543.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 536-543
    • Weggen, S.1    Rogers, M.2    Eriksen, J.3
  • 16
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane, J. R., Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat. New Biol. 1971. 231: 232-235.
    • (1971) Nat. New Biol. , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 17
    • 4143107932 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition
    • Simmons, D. L., Botting, R. M. and Hla, T., Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol. Rev. 2004. 56: 387-437.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 387-437
    • Simmons, D.L.1    Botting, R.M.2    Hla, T.3
  • 19
    • 80054072295 scopus 로고    scopus 로고
    • Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis
    • Smith, W. L., Urade, Y. and Jakobsson, P. J., Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem. Rev. 2011. 111: 5821-5865.
    • (2011) Chem. Rev. , vol.111 , pp. 5821-5865
    • Smith, W.L.1    Urade, Y.2    Jakobsson, P.J.3
  • 20
    • 84924577612 scopus 로고    scopus 로고
    • Firestein, G. S., Budd, R. C., Harris, E. D., MacInnes, I. B., Ruddy, S. and Sergent, J. S. (Eds.), Kelleýs textbook of rheumatology, 8th Edn. Saunders Elsevier, Philadelphia -.
    • Ballou, L. R. and Wang, B. W. E., Nonsteroidal Anti-inflammatory Drugs. In Firestein, G. S., Budd, R. C., Harris, E. D., MacInnes, I. B., Ruddy, S. and Sergent, J. S. (Eds.), Kelleýs textbook of rheumatology, 8th Edn. Saunders Elsevier, Philadelphia 2009, pp. 833-862.
    • (2009) Nonsteroidal Anti-inflammatory Drugs , pp. 833-862
    • Ballou, L.R.1    Wang, B.W.E.2
  • 21
    • 0020965569 scopus 로고
    • Anti-inflammatory effects of prostaglandin E1: in vivo modulation of the formyl peptide chemotactic receptor on the rat neutrophil
    • Fantone, J. C., Marasco, W. A., Elgas, L. J. and Ward, P. A., Anti-inflammatory effects of prostaglandin E1: in vivo modulation of the formyl peptide chemotactic receptor on the rat neutrophil. J. Immunol. 1983. 130: 1495-1497.
    • (1983) J. Immunol. , vol.130 , pp. 1495-1497
    • Fantone, J.C.1    Marasco, W.A.2    Elgas, L.J.3    Ward, P.A.4
  • 22
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell, J. A., Akarasereenont, P., Thiemermann, C., Flower, R. J. and Vane, J. R., Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA 1993. 90: 11693-11697.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 23
    • 0028925302 scopus 로고
    • Salsalate, a nonacetylated salicylate, is as efficacious as diclofenac in patients with rheumatoid arthritis. Salsalate-Diclofenac Study Group
    • Bombardier, C., Peloso, P. M. and Goldsmith, C. H., Salsalate, a nonacetylated salicylate, is as efficacious as diclofenac in patients with rheumatoid arthritis. Salsalate-Diclofenac Study Group. J. Rheumatol. 1995. 22: 617-624.
    • (1995) J. Rheumatol. , vol.22 , pp. 617-624
    • Bombardier, C.1    Peloso, P.M.2    Goldsmith, C.H.3
  • 24
    • 0024528916 scopus 로고
    • The mechanisms of action of nonsteroidal antiinflammatory drugs
    • Abramson, S. B. and Weissmann, G., The mechanisms of action of nonsteroidal antiinflammatory drugs. Arthritis Rheum. 1989. 32: 1-9.
    • (1989) Arthritis Rheum. , vol.32 , pp. 1-9
    • Abramson, S.B.1    Weissmann, G.2
  • 25
    • 0028818913 scopus 로고
    • Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
    • Dinchuk, J. E., Car, B. D., Focht, R. J., Johnston, J. J., Jaffee, B. D., Covington, M. B., Contel, N. R. et al., Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995. 378: 406-409.
    • (1995) Nature , vol.378 , pp. 406-409
    • Dinchuk, J.E.1    Car, B.D.2    Focht, R.J.3    Johnston, J.J.4    Jaffee, B.D.5    Covington, M.B.6    Contel, N.R.7
  • 27
    • 0028843881 scopus 로고
    • Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
    • Langenbach, R., Morham, S. G., Tiano, H. F., Loftin, C. D., Ghanayem, B. I., Chulada, P. C., Mahler, J. F. et al., Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995. 83: 483-492.
    • (1995) Cell , vol.83 , pp. 483-492
    • Langenbach, R.1    Morham, S.G.2    Tiano, H.F.3    Loftin, C.D.4    Ghanayem, B.I.5    Chulada, P.C.6    Mahler, J.F.7
  • 28
    • 0030777729 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders
    • Walker, J. S., Sheather-Reid, R. B., Carmody, J. J., Vial, J. H. and Day, R. O., Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders". Arthritis Rheum. 1997. 40: 1944-1954.
    • (1997) Arthritis Rheum. , vol.40 , pp. 1944-1954
    • Walker, J.S.1    Sheather-Reid, R.B.2    Carmody, J.J.3    Vial, J.H.4    Day, R.O.5
  • 29
    • 84860820855 scopus 로고    scopus 로고
    • Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine
    • Lichtenberger, L. M., Zhou, Y., Jayaraman, V., Doyen, J. R., O'Neil, R. G., Dial, E. J., Volk, D. E. et al., Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine. Biochim. Biophys. Acta 2012. 1821: 994-1002.
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 994-1002
    • Lichtenberger, L.M.1    Zhou, Y.2    Jayaraman, V.3    Doyen, J.R.4    O'Neil, R.G.5    Dial, E.J.6    Volk, D.E.7
  • 30
    • 0025319927 scopus 로고
    • Neutrophil activation: an alternative to prostaglandin inhibition as the mechanism of action for NSAIDs
    • Altman, R. D., Neutrophil activation: an alternative to prostaglandin inhibition as the mechanism of action for NSAIDs. Semin. Arthritis Rheum. 1990. 19: 1-5.
    • (1990) Semin. Arthritis Rheum. , vol.19 , pp. 1-5
    • Altman, R.D.1
  • 31
    • 84903205231 scopus 로고    scopus 로고
    • Neutrophil migration towards C5a and CXCL8 is prevented by non-steroidal anti-inflammatory drugs via inhibition of different pathways
    • Bertolotto, M., Contini, P., Ottonello, L., Pende, A., Dallegri, F. and Montecucco, F., Neutrophil migration towards C5a and CXCL8 is prevented by non-steroidal anti-inflammatory drugs via inhibition of different pathways. Br. J. Pharmacol. 2014. 171: 3376-3393.
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 3376-3393
    • Bertolotto, M.1    Contini, P.2    Ottonello, L.3    Pende, A.4    Dallegri, F.5    Montecucco, F.6
  • 32
    • 0035109560 scopus 로고    scopus 로고
    • Mechanism of superoxide generation system in indomethacin-induced gastric mucosal injury in rats
    • Tanaka, J., Yuda, Y. and Yamakawa, T., Mechanism of superoxide generation system in indomethacin-induced gastric mucosal injury in rats. Biol. Pharm. Bull. 2001. 24: 155-158.
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 155-158
    • Tanaka, J.1    Yuda, Y.2    Yamakawa, T.3
  • 34
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases
    • Barnes, P. J. and Karin, M., Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 1997. 336: 1066-1071.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 35
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • Yin, M. J., Yamamoto, Y. and Gaynor, R. B., The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 1998. 396: 77-80.
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 36
    • 0029842020 scopus 로고    scopus 로고
    • Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin
    • Sakurada, S., Kato, T. and Okamoto, T., Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin. Int. Immunol. 1996. 8: 1483-1493.
    • (1996) Int. Immunol. , vol.8 , pp. 1483-1493
    • Sakurada, S.1    Kato, T.2    Okamoto, T.3
  • 37
  • 38
    • 0028951498 scopus 로고
    • Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells
    • Weber, C., Erl, W., Pietsch, A. and Weber, P. C., Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation 1995. 91: 1914-1917.
    • (1995) Circulation , vol.91 , pp. 1914-1917
    • Weber, C.1    Erl, W.2    Pietsch, A.3    Weber, P.C.4
  • 39
    • 0031990814 scopus 로고    scopus 로고
    • Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen
    • Scheuren, N., Bang, H., Munster, T., Brune, K. and Pahl, A., Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br. J. Pharmacol. 1998. 123: 645-652.
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 645-652
    • Scheuren, N.1    Bang, H.2    Munster, T.3    Brune, K.4    Pahl, A.5
  • 40
    • 0028795227 scopus 로고
    • Suppression of NF kappa B activation and NF kappa B-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase
    • Kazmi, S. M., Plante, R. K., Visconti, V., Taylor, G. R., Zhou, L. and Lau, C. Y., Suppression of NF kappa B activation and NF kappa B-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase. J Cell. Biochem. 1995. 57: 299-310.
    • (1995) J Cell. Biochem. , vol.57 , pp. 299-310
    • Kazmi, S.M.1    Plante, R.K.2    Visconti, V.3    Taylor, G.R.4    Zhou, L.5    Lau, C.Y.6
  • 41
    • 34247092489 scopus 로고    scopus 로고
    • Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT
    • Ou, Y. C., Yang, C. R., Cheng, C. L., Raung, S. L., Hung, Y. Y. and Chen, C. J., Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT. Eur. J. Pharmacol. 2007. 563: 49-60.
    • (2007) Eur. J. Pharmacol. , vol.563 , pp. 49-60
    • Ou, Y.C.1    Yang, C.R.2    Cheng, C.L.3    Raung, S.L.4    Hung, Y.Y.5    Chen, C.J.6
  • 42
    • 78049513349 scopus 로고    scopus 로고
    • The role of NF-kappaB and PPARgamma in experimentally induced colorectal cancer and chemoprevention by cyclooxygenase-2 inhibitors
    • Vaish, V., Tanwar, L. and Sanyal, S. N., The role of NF-kappaB and PPARgamma in experimentally induced colorectal cancer and chemoprevention by cyclooxygenase-2 inhibitors. Tumour Biol. 2010. 31: 427-436.
    • (2010) Tumour Biol. , vol.31 , pp. 427-436
    • Vaish, V.1    Tanwar, L.2    Sanyal, S.N.3
  • 43
    • 24344444134 scopus 로고    scopus 로고
    • Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention
    • Kashfi, K. and Rigas, B., Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention. Biochem. Pharmacol. 2005. 70: 969-986.
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 969-986
    • Kashfi, K.1    Rigas, B.2
  • 45
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: the leukocyte adhesion cascade updated
    • Ley, K., Laudanna, C., Cybulsky, M. I. and Nourshargh, S., Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 2007. 7: 678-689.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 46
    • 77954179519 scopus 로고    scopus 로고
    • Anti-adhesion molecule therapy for inflammatory bowel disease
    • Ghosh, S. and Panaccione, R., Anti-adhesion molecule therapy for inflammatory bowel disease. Therap. Adv. Gastroenterol. 2010. 3: 239-258.
    • (2010) Therap. Adv. Gastroenterol. , vol.3 , pp. 239-258
    • Ghosh, S.1    Panaccione, R.2
  • 47
    • 84879496433 scopus 로고    scopus 로고
    • Targeting cells in motion: migrating toward improved therapies
    • Griffith, J. W. and Luster, A. D., Targeting cells in motion: migrating toward improved therapies. Eur. J. Immunol. 2013. 43: 1430-1435.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 1430-1435
    • Griffith, J.W.1    Luster, A.D.2
  • 48
    • 84901288697 scopus 로고    scopus 로고
    • Therapeutic potential of carbohydrate-based polymeric and nanoparticle systems
    • Sunasee, R., Adokoh, C. K., Darkwa, J. and Narain, R., Therapeutic potential of carbohydrate-based polymeric and nanoparticle systems. Expert Opin. Drug Deliv. 2014. 11: 867-884.
    • (2014) Expert Opin. Drug Deliv. , vol.11 , pp. 867-884
    • Sunasee, R.1    Adokoh, C.K.2    Darkwa, J.3    Narain, R.4
  • 49
    • 80055107448 scopus 로고    scopus 로고
    • Comparative in vitro dissolution and in vivo bioequivalence of two diclofenac enteric coated formulations
    • Basmenji, S., Valizadeh, H. and Zakeri-Milani, P., Comparative in vitro dissolution and in vivo bioequivalence of two diclofenac enteric coated formulations. Arzneimittelforschung 2011. 61: 566-570.
    • (2011) Arzneimittelforschung , vol.61 , pp. 566-570
    • Basmenji, S.1    Valizadeh, H.2    Zakeri-Milani, P.3
  • 52
    • 34250181263 scopus 로고    scopus 로고
    • Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding
    • Gomez-Gaviro, M., Dominguez-Luis, M., Canchado, J., Calafat, J., Janssen, H., Lara-Pezzi, E., Fourie, A. et al., Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding. J. Immunol. 2007. 178: 8053-8063.
    • (2007) J. Immunol. , vol.178 , pp. 8053-8063
    • Gomez-Gaviro, M.1    Dominguez-Luis, M.2    Canchado, J.3    Calafat, J.4    Janssen, H.5    Lara-Pezzi, E.6    Fourie, A.7
  • 53
    • 24044469049 scopus 로고    scopus 로고
    • L-selectin: mechanisms and physiological significance of ectodomain cleavage
    • Smalley, D. M. and Ley, K., L-selectin: mechanisms and physiological significance of ectodomain cleavage. J. Cell Mol. Med. 2005. 9: 255-266.
    • (2005) J. Cell Mol. Med. , vol.9 , pp. 255-266
    • Smalley, D.M.1    Ley, K.2
  • 54
    • 0026660377 scopus 로고
    • Soluble L-selectin is present in human plasma at high levels and retains functional activity
    • Schleiffenbaum, B., Spertini, O. and Tedder, T. F., Soluble L-selectin is present in human plasma at high levels and retains functional activity. J. Cell Biol. 1992. 119: 229-238.
    • (1992) J. Cell Biol. , vol.119 , pp. 229-238
    • Schleiffenbaum, B.1    Spertini, O.2    Tedder, T.F.3
  • 55
    • 0036345148 scopus 로고    scopus 로고
    • Soluble L-selectin attenuates tumor necrosis factor-alpha-mediated leukocyte adherence and vascular permeability: a protective role for elevated soluble L-selectin in sepsis
    • Ferri, L. E., Pascual, J., Seely, A. J., Chaudhury, P. and Christou, N. V., Soluble L-selectin attenuates tumor necrosis factor-alpha-mediated leukocyte adherence and vascular permeability: a protective role for elevated soluble L-selectin in sepsis. Crit. Care Med. 2002. 30: 1842-1847.
    • (2002) Crit. Care Med. , vol.30 , pp. 1842-1847
    • Ferri, L.E.1    Pascual, J.2    Seely, A.J.3    Chaudhury, P.4    Christou, N.V.5
  • 56
    • 0035260351 scopus 로고    scopus 로고
    • Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate
    • Zhang, Z., Oliver, P., Lancaster, J. R., Jr., Schwarzenberger, P. O., Joshi, M. S., Cork, J. and Kolls, J. K., Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate. FASEB J. 2001. 15: 303-305.
    • (2001) FASEB J. , vol.15 , pp. 303-305
    • Zhang, Z.1    Oliver, P.2    Lancaster Jr, J.R.3    Schwarzenberger, P.O.4    Joshi, M.S.5    Cork, J.6    Kolls, J.K.7
  • 57
    • 0034704120 scopus 로고    scopus 로고
    • Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly
    • Gorzalczany, Y., Sigal, N., Itan, M., Lotan, O. and Pick, E., Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly. J. Biol. Chem. 2000. 275: 40073-40081.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40073-40081
    • Gorzalczany, Y.1    Sigal, N.2    Itan, M.3    Lotan, O.4    Pick, E.5
  • 59
    • 72449156722 scopus 로고    scopus 로고
    • Leukocyte integrins and their ligand interactions
    • Hyun, Y. M., Lefort, C. T. and Kim, M., Leukocyte integrins and their ligand interactions. Immunol. Res. 2009. 45: 195-208.
    • (2009) Immunol. Res. , vol.45 , pp. 195-208
    • Hyun, Y.M.1    Lefort, C.T.2    Kim, M.3
  • 60
    • 0032858268 scopus 로고    scopus 로고
    • Anti-L-selectin antibody treatment of hemorrhagic-traumatic shock in baboons
    • Schlag, G., Redl, H. R., Till, G. O., Davies, J., Martin, U. and Dumont, L., Anti-L-selectin antibody treatment of hemorrhagic-traumatic shock in baboons. Crit. Care. Med. 1999. 27: 1900-1907.
    • (1999) Crit. Care. Med. , vol.27 , pp. 1900-1907
    • Schlag, G.1    Redl, H.R.2    Till, G.O.3    Davies, J.4    Martin, U.5    Dumont, L.6
  • 61
    • 0030975020 scopus 로고    scopus 로고
    • The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand
    • Takada, M., Nadeau, K. C., Shaw, G. D., Marquette, K. A. and Tilney, N. L., The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand. J. Clin. Invest. 1997. 99: 2682-2690.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2682-2690
    • Takada, M.1    Nadeau, K.C.2    Shaw, G.D.3    Marquette, K.A.4    Tilney, N.L.5
  • 62
    • 50049089619 scopus 로고    scopus 로고
    • Moving targets: cell migration inhibitors as new anti-inflammatory therapies
    • Mackay, C. R., Moving targets: cell migration inhibitors as new anti-inflammatory therapies. Nat. Immunol. 2008. 9: 988-998.
    • (2008) Nat. Immunol. , vol.9 , pp. 988-998
    • Mackay, C.R.1
  • 63
    • 5644300385 scopus 로고    scopus 로고
    • The effect of anti-L-selectin (aselizumab) in multiple traumatized patients-results of a phase II clinical trial
    • Seekamp, A., van Griensven, M., Dhondt, E., Diefenbeck, M., Demeyer, I., Vundelinckx, G., Haas, N. et al., The effect of anti-L-selectin (aselizumab) in multiple traumatized patients-results of a phase II clinical trial. Crit. Care Med. 2004. 32: 2021-2028.
    • (2004) Crit. Care Med. , vol.32 , pp. 2021-2028
    • Seekamp, A.1    Griensven van, M.2    Dhondt, E.3    Diefenbeck, M.4    Demeyer, I.5    Vundelinckx, G.6    Haas, N.7
  • 64
    • 40949086098 scopus 로고    scopus 로고
    • Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia
    • Mayr, F. B., Firbas, C., Leitner, J. M., Spiel, A. O., Reiter, R. A., Beyer, D., Meyer, M. et al., Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia. Shock 2008. 29: 475-482.
    • (2008) Shock , vol.29 , pp. 475-482
    • Mayr, F.B.1    Firbas, C.2    Leitner, J.M.3    Spiel, A.O.4    Reiter, R.A.5    Beyer, D.6    Meyer, M.7
  • 70
    • 0031704871 scopus 로고    scopus 로고
    • Interference of nonsteroidal antiinflammatory drugs with very late activation antigen 4/vascular cells adhesion molecule 1-mediated lymphocyte-endothelial cell adhesion
    • Gonzalez-Alvaro, I., Munoz, C., Garcia-Vicuna, R., Sabando, P., Cabanas, C., Sanchez-Madrid, F. and Diaz-Gonzalez, F., Interference of nonsteroidal antiinflammatory drugs with very late activation antigen 4/vascular cells adhesion molecule 1-mediated lymphocyte-endothelial cell adhesion. Arthritis Rheum. 1998. 41: 1677-1688.
    • (1998) Arthritis Rheum. , vol.41 , pp. 1677-1688
    • Gonzalez-Alvaro, I.1    Munoz, C.2    Garcia-Vicuna, R.3    Sabando, P.4    Cabanas, C.5    Sanchez-Madrid, F.6    Diaz-Gonzalez, F.7
  • 71
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF-kappaB pathway
    • Yamamoto, Y., Yin, M. J., Lin, K. M. and Gaynor, R. B., Sulindac inhibits activation of the NF-kappaB pathway. J. Biol. Chem. 1999. 274: 27307-27314.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 72
    • 42549170070 scopus 로고    scopus 로고
    • Indomethacin enhances the cytotoxicity of recombinant human lymphotoxin alpha on tumor cells by suppressing NFkappaB signaling
    • Shen, Y., Yang, T., Wang, J., Xu, Q., Li, R., Pan, W., Li, G. et al., Indomethacin enhances the cytotoxicity of recombinant human lymphotoxin alpha on tumor cells by suppressing NFkappaB signaling. Cancer Biol. Ther. 2007. 6: 1428-1433.
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 1428-1433
    • Shen, Y.1    Yang, T.2    Wang, J.3    Xu, Q.4    Li, R.5    Pan, W.6    Li, G.7
  • 73
    • 0029875122 scopus 로고    scopus 로고
    • Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils
    • Gonzalez-Alvaro, I., Carmona, L., Diaz-Gonzalez, F., Gonzalez-Amaro, R., Mollinedo, F., Sanchez-Madrid, F., Laffon, A. et al., Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. J. Rheumatol. 1996. 23: 723-729.
    • (1996) J. Rheumatol. , vol.23 , pp. 723-729
    • Gonzalez-Alvaro, I.1    Carmona, L.2    Diaz-Gonzalez, F.3    Gonzalez-Amaro, R.4    Mollinedo, F.5    Sanchez-Madrid, F.6    Laffon, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.