메뉴 건너뛰기




Volumn 45, Issue 2-3, 2009, Pages 195-208

Leukocyte integrins and their ligand interactions

Author keywords

Integrin; LFA 1; Mac 1; VLA 4

Indexed keywords

ABCIXIMAB; ALPHA4 INTEGRIN; BETA GLUCAN; BLOOD CLOTTING FACTOR 10; CD11B ANTIGEN; CD11B ANTIGEN ANTIBODY; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; EFALIZUMAB; FIBRINOGEN; FIBRONECTIN; IMMUNOMODULATING AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; INTERCELLULAR ADHESION MOLECULE 3; INTERCELLULAR ADHESION MOLECULE 4; INTERCELLULAR ADHESION MOLECULE 5; LYMPHOCYTE ANTIBODY; LYMPHOCYTE ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 ANTAGONIST; NATALIZUMAB; NEUTROPHIL INHIBITORY FACTOR; RECOMBINANT NEUTROPHIL INHIBITORY FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

EID: 72449156722     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-009-8101-1     Document Type: Review
Times cited : (52)

References (123)
  • 1
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multi-step paradigm
    • 7507411
    • TA Springer 1994 Traffic signals for lymphocyte recirculation and leukocyte emigration: the multi-step paradigm Cell 76 301 14 7507411
    • (1994) Cell , vol.76 , pp. 301-14
    • Springer, T.A.1
  • 2
    • 0142026204 scopus 로고    scopus 로고
    • Therapeutic antagonists and the conformational regulation of integrin structure and function
    • 12951577
    • M Shimaoka TA Springer 2003 Therapeutic antagonists and the conformational regulation of integrin structure and function Nat Rev Drug Discov 2 703 16 12951577
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 703-16
    • Shimaoka, M.1    Springer, T.A.2
  • 4
    • 34447649346 scopus 로고    scopus 로고
    • Unique and redundant roles of alpha4 and beta2 integrins in kinetics of recruitment of lymphoid vs myeloid cell subsets to the inflamed peritoneum revealed by studies of genetically deficient mice
    • 17553614
    • T Ulyanova GV Priestley ER Banerjee T Papayannopoulou 2007 Unique and redundant roles of alpha4 and beta2 integrins in kinetics of recruitment of lymphoid vs myeloid cell subsets to the inflamed peritoneum revealed by studies of genetically deficient mice Exp Hematol 35 1256 65 17553614
    • (2007) Exp Hematol , vol.35 , pp. 1256-65
    • Ulyanova, T.1    Priestley, G.V.2    Banerjee, E.R.3    Papayannopoulou, T.4
  • 5
    • 33645764646 scopus 로고    scopus 로고
    • The LFA-1 adhesion molecule is required for protective immunity during pulmonary Mycobacterium tuberculosis infection
    • 16585587
    • S Ghosh AA Chackerian CM Parker CM Ballantyne SM Behar 2006 The LFA-1 adhesion molecule is required for protective immunity during pulmonary Mycobacterium tuberculosis infection J Immunol 176 4914 22 16585587
    • (2006) J Immunol , vol.176 , pp. 4914-22
    • Ghosh, S.1    Chackerian, A.A.2    Parker, C.M.3    Ballantyne, C.M.4    Behar, S.M.5
  • 6
    • 0023644247 scopus 로고
    • Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)
    • 3315233
    • SD Marlin TA Springer 1987 Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1) Cell 51 813 9 3315233
    • (1987) Cell , vol.51 , pp. 813-9
    • Marlin, S.D.1    Springer, T.A.2
  • 7
    • 0025860094 scopus 로고
    • Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1
    • 1676048
    • AR de Fougerolles SA Stacker R Schwarting TA Springer 1991 Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1 J Exp Med 174 253 67 1676048
    • (1991) J Exp Med , vol.174 , pp. 253-67
    • De Fougerolles, A.R.1    Stacker, S.A.2    Schwarting, R.3    Springer, T.A.4
  • 8
    • 0027982997 scopus 로고
    • Characterization of the function of ICAM-3 and comparison to ICAM-1 and ICAM-2 in immune responses
    • 7905020
    • AR de Fougerolles X Qin TA Springer 1994 Characterization of the function of ICAM-3 and comparison to ICAM-1 and ICAM-2 in immune responses J Exp Med 179 619 29 7905020
    • (1994) J Exp Med , vol.179 , pp. 619-29
    • De Fougerolles, A.R.1    Qin, X.2    Springer, T.A.3
  • 9
    • 0033999503 scopus 로고    scopus 로고
    • Binding of T lymphocytes to hippocampal neurons through ICAM-5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18
    • 10741396
    • L Tian P Kilgannon Y Yoshihara K Mori WM Gallatin O Carpen CG Gahmberg 2000 Binding of T lymphocytes to hippocampal neurons through ICAM-5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18 Eur J Immunol 30 810 8 10741396
    • (2000) Eur J Immunol , vol.30 , pp. 810-8
    • Tian, L.1    Kilgannon, P.2    Yoshihara, Y.3    Mori, K.4    Gallatin, W.M.5    Carpen, O.6    Gahmberg, C.G.7
  • 11
    • 0036008013 scopus 로고    scopus 로고
    • JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes
    • 11812992
    • G Ostermann KS Weber A Zernecke A Schroder C Weber 2002 JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes Nat Immunol 3 151 8 11812992
    • (2002) Nat Immunol , vol.3 , pp. 151-8
    • Ostermann, G.1    Weber, K.S.2    Zernecke, A.3    Schroder, A.4    Weber, C.5
  • 12
    • 0031847681 scopus 로고    scopus 로고
    • Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses
    • 9700512
    • J Wang TA Springer 1998 Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses Immunol Rev 163 197 215 9700512
    • (1998) Immunol Rev , vol.163 , pp. 197-215
    • Wang, J.1    Springer, T.A.2
  • 14
    • 0025314483 scopus 로고
    • The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells
    • 1972160
    • G van Seventer Y Shimizu K Horgan S Shaw 1990 The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells J Immunol 144 4579 86 1972160
    • (1990) J Immunol , vol.144 , pp. 4579-86
    • Van Seventer, G.1    Shimizu, Y.2    Horgan, K.3    Shaw, S.4
  • 15
    • 0022552576 scopus 로고
    • Identification and partial characterization of the human erythrocyte membrane component(s) that express the antigens of the LW blood-group system
    • 2424433
    • G Mallinson PG Martin DJ Anstee MJ Tanner AH Merry D Tills HH Sonneborn 1986 Identification and partial characterization of the human erythrocyte membrane component(s) that express the antigens of the LW blood-group system Biochem J 234 649 52 2424433
    • (1986) Biochem J , vol.234 , pp. 649-52
    • Mallinson, G.1    Martin, P.G.2    Anstee, D.J.3    Tanner, M.J.4    Merry, A.H.5    Tills, D.6    Sonneborn, H.H.7
  • 16
    • 0034004457 scopus 로고    scopus 로고
    • Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
    • 10688643
    • K Katagiri M Hattori N Minato S Irie K Takatsu T Kinashi 2000 Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase Mol Cell Biol 20 1956 69 10688643
    • (2000) Mol Cell Biol , vol.20 , pp. 1956-69
    • Katagiri, K.1    Hattori, M.2    Minato, N.3    Irie, S.4    Takatsu, K.5    Kinashi, T.6
  • 19
    • 36349034646 scopus 로고    scopus 로고
    • Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion
    • 17702895
    • H Ghandour X Cullere A Alvarez FW Luscinskas TN Mayadas 2007 Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion Blood 110 3682 90 17702895
    • (2007) Blood , vol.110 , pp. 3682-90
    • Ghandour, H.1    Cullere, X.2    Alvarez, A.3    Luscinskas, F.W.4    Mayadas, T.N.5
  • 21
    • 2342597085 scopus 로고    scopus 로고
    • Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL
    • 15134891
    • T Kinashi K Katagiri 2004 Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL Immunol Lett 93 1 5 15134891
    • (2004) Immunol Lett , vol.93 , pp. 1-5
    • Kinashi, T.1    Katagiri, K.2
  • 22
    • 33747623042 scopus 로고    scopus 로고
    • Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
    • 16892067
    • K Katagiri M Imamura T Kinashi 2006 Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion Nat Immunol 7 919 28 16892067
    • (2006) Nat Immunol , vol.7 , pp. 919-28
    • Katagiri, K.1    Imamura, M.2    Kinashi, T.3
  • 23
    • 0042490495 scopus 로고    scopus 로고
    • RAPL, a novel Rap1-binding molecule, mediates Rap1-induced adhesion through spatial regulation of LFA-1
    • 12845325
    • K Katagiri A Maeda M Shimonaka T Kinashi 2003 RAPL, a novel Rap1-binding molecule, mediates Rap1-induced adhesion through spatial regulation of LFA-1 Nat Immunol 4 741 8 12845325
    • (2003) Nat Immunol , vol.4 , pp. 741-8
    • Katagiri, K.1    Maeda, A.2    Shimonaka, M.3    Kinashi, T.4
  • 26
    • 34447314985 scopus 로고    scopus 로고
    • Integrin modulation and signaling in leukocyte adhesion and migration
    • 17624949
    • DM Rose R Alon MH Ginsberg 2007 Integrin modulation and signaling in leukocyte adhesion and migration Immunol Rev 218 126 34 17624949
    • (2007) Immunol Rev , vol.218 , pp. 126-34
    • Rose, D.M.1    Alon, R.2    Ginsberg, M.H.3
  • 27
    • 0036150120 scopus 로고    scopus 로고
    • The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function
    • 11809807
    • X Li X Bu B Lu H Avraham RA Flavell B Lim 2002 The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function Mol Cell Biol 22 1158 71 11809807
    • (2002) Mol Cell Biol , vol.22 , pp. 1158-71
    • Li, X.1    Bu, X.2    Lu, B.3    Avraham, H.4    Flavell, R.A.5    Lim, B.6
  • 28
    • 4644370560 scopus 로고    scopus 로고
    • RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes
    • 15300248
    • LK Cherry X Li P Schwab B Lim LB Klickstein 2004 RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes Nat Immunol 5 961 7 15300248
    • (2004) Nat Immunol , vol.5 , pp. 961-7
    • Cherry, L.K.1    Li, X.2    Schwab, P.3    Lim, B.4    Klickstein, L.B.5
  • 29
    • 0034611731 scopus 로고    scopus 로고
    • Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity
    • 10766246
    • E Bianchi S Denti A Granata G Bossi J Geginat A Villa L Rogge R Pardi 2000 Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity Nature 404 617 21 10766246
    • (2000) Nature , vol.404 , pp. 617-21
    • Bianchi, E.1    Denti, S.2    Granata, A.3    Bossi, G.4    Geginat, J.5    Villa, A.6    Rogge, L.7    Pardi, R.8
  • 30
    • 0030602819 scopus 로고    scopus 로고
    • αlβ2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule
    • 8706128
    • W Kolanus W Nagel B Schiller L Zeitlmann S Godar H Stockinger B Seed 1996 αLβ2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule Cell 86 233 42 8706128
    • (1996) Cell , vol.86 , pp. 233-42
    • Kolanus, W.1    Nagel, W.2    Schiller, B.3    Zeitlmann, L.4    Godar, S.5    Stockinger, H.6    Seed, B.7
  • 31
    • 0035846547 scopus 로고    scopus 로고
    • Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines
    • 11747824
    • KS Weber C Weber G Ostermann H Dierks W Nagel W Kolanus 2001 Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines Curr Biol 11 1969 74 11747824
    • (2001) Curr Biol , vol.11 , pp. 1969-74
    • Weber, K.S.1    Weber, C.2    Ostermann, G.3    Dierks, H.4    Nagel, W.5    Kolanus, W.6
  • 32
    • 34447301486 scopus 로고    scopus 로고
    • Small GTPases and LFA-1 reciprocally modulate adhesion and signaling
    • 17624948
    • A Mor ML Dustin MR Philips 2007 Small GTPases and LFA-1 reciprocally modulate adhesion and signaling Immunol Rev 218 114 25 17624948
    • (2007) Immunol Rev , vol.218 , pp. 114-25
    • Mor, A.1    Dustin, M.L.2    Philips, M.R.3
  • 33
    • 0242708766 scopus 로고    scopus 로고
    • Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1
    • 14528303
    • OD Perez D Mitchell GC Jager S South C Murriel J McBride LA Herzenberg S Kinoshita GP Nolan 2003 Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1 Nat Immunol 4 1083 92 14528303
    • (2003) Nat Immunol , vol.4 , pp. 1083-92
    • Perez, O.D.1    Mitchell, D.2    Jager, G.C.3    South, S.4    Murriel, C.5    McBride, J.6    Herzenberg, L.A.7    Kinoshita, S.8    Nolan, G.P.9
  • 34
    • 0033005168 scopus 로고    scopus 로고
    • Molecular mechanisms of nonmuscle myosin-II regulation
    • 10047526
    • AR Bresnick 1999 Molecular mechanisms of nonmuscle myosin-II regulation Curr Opin Cell Biol 11 26 33 10047526
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 26-33
    • Bresnick, A.R.1
  • 38
    • 21644478072 scopus 로고    scopus 로고
    • Anti-adhesion therapies
    • 15955735
    • DL Simmons 2005 Anti-adhesion therapies Curr Opin Pharmacol 5 398 404 15955735
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 398-404
    • Simmons, D.L.1
  • 40
    • 0025973002 scopus 로고
    • Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: A European Group for immunodeficiency/European Group for bone marrow transplantation report
    • 1985691
    • A Fischer W Friedrich A Fasth S Blanche F Le Deist D Girault F Veber J Vossen M Lopez C Griscelli, et al. 1991 Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: a European Group for immunodeficiency/European Group for bone marrow transplantation report Blood 77 249 56 1985691
    • (1991) Blood , vol.77 , pp. 249-56
    • Fischer, A.1    Friedrich, W.2    Fasth, A.3    Blanche, S.4    Le Deist, F.5    Girault, D.6    Veber, F.7    Vossen, J.8    Lopez, M.9    Griscelli, C.10
  • 41
    • 27444447882 scopus 로고    scopus 로고
    • Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: Two-edged swords?
    • 16236118
    • R Gonzalez-Amaro M Mittelbrunn F Sanchez-Madrid 2005 Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords? Immunology 116 289 96 16236118
    • (2005) Immunology , vol.116 , pp. 289-96
    • Gonzalez-Amaro, R.1    Mittelbrunn, M.2    Sanchez-Madrid, F.3
  • 44
    • 47249143701 scopus 로고    scopus 로고
    • Integrin-associated proteins as potential therapeutic targets
    • 18613840
    • JM Cantor MH Ginsberg DM Rose 2008 Integrin-associated proteins as potential therapeutic targets Immunol Rev 223 236 51 18613840
    • (2008) Immunol Rev , vol.223 , pp. 236-51
    • Cantor, J.M.1    Ginsberg, M.H.2    Rose, D.M.3
  • 45
    • 0018758819 scopus 로고
    • Mac-1: A macrophage differentiation antigen identified by monoclonal antibody
    • 89034
    • T Springer G Galfre DS Secher C Milstein 1979 Mac-1: a macrophage differentiation antigen identified by monoclonal antibody Eur J Immunol 9 301 6 89034
    • (1979) Eur J Immunol , vol.9 , pp. 301-6
    • Springer, T.1    Galfre, G.2    Secher, D.S.3    Milstein, C.4
  • 46
    • 0031569082 scopus 로고    scopus 로고
    • A MAC-1 attack: Integrin functions directly challenged in knockout mice
    • 9077518
    • EF Plow L Zhang 1997 A MAC-1 attack: integrin functions directly challenged in knockout mice J Clin Invest 99 1145 6 9077518
    • (1997) J Clin Invest , vol.99 , pp. 1145-6
    • Plow, E.F.1    Zhang, L.2
  • 47
    • 0026708995 scopus 로고
    • CD11b (Mac-1): A marker for CD8+ cytotoxic T cell activation and memory in virus infection
    • 1500720
    • HI McFarland SR Nahill JW Maciaszek RM Welsh 1992 CD11b (Mac-1): a marker for CD8+ cytotoxic T cell activation and memory in virus infection J Immunol 149 1326 33 1500720
    • (1992) J Immunol , vol.149 , pp. 1326-33
    • McFarland, H.I.1    Nahill, S.R.2    MacIaszek, J.W.3    Welsh, R.M.4
  • 48
    • 0021707124 scopus 로고
    • Inherited deficiency of the Mac-1, LFA-1, p150, 95 glycoprotein family and its molecular basis
    • 6096477
    • TA Springer WS Thompson LJ Miller FC Schmalstieg DC Anderson 1984 Inherited deficiency of the Mac-1, LFA-1, p150, 95 glycoprotein family and its molecular basis J Exp Med 160 1901 18 6096477
    • (1984) J Exp Med , vol.160 , pp. 1901-18
    • Springer, T.A.1    Thompson, W.S.2    Miller, L.J.3    Schmalstieg, F.C.4    Anderson, D.C.5
  • 49
    • 0023387994 scopus 로고
    • Stimulated mobilization of monocyte Mac-1 and p150, 95 adhesion proteins from an intracellular vesicular compartment to the cell surface
    • 3038962
    • LJ Miller DF Bainton N Borregaard TA Springer 1987 Stimulated mobilization of monocyte Mac-1 and p150, 95 adhesion proteins from an intracellular vesicular compartment to the cell surface J Clin Invest 80 535 44 3038962
    • (1987) J Clin Invest , vol.80 , pp. 535-44
    • Miller, L.J.1    Bainton, D.F.2    Borregaard, N.3    Springer, T.A.4
  • 50
    • 0021691099 scopus 로고
    • Subcellular localization of the large subunit of Mo1 (Mo1 alpha; Formerly gp 110), a surface glycoprotein associated with neutrophil adhesion
    • 6480827
    • RF Todd III MA Arnaout RE Rosin CA Crowley WA Peters BM Babior 1984 Subcellular localization of the large subunit of Mo1 (Mo1 alpha; formerly gp 110), a surface glycoprotein associated with neutrophil adhesion J Clin Invest 74 1280 90 6480827
    • (1984) J Clin Invest , vol.74 , pp. 1280-90
    • Todd Iii, R.F.1    Arnaout, M.A.2    Rosin, R.E.3    Crowley, C.A.4    Peters, W.A.5    Babior, B.M.6
  • 51
    • 0023851511 scopus 로고
    • Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium
    • 3278004
    • NB Vedder JM Harlan 1988 Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium J Clin Invest 81 676 82 3278004
    • (1988) J Clin Invest , vol.81 , pp. 676-82
    • Vedder, N.B.1    Harlan, J.M.2
  • 52
    • 0027398448 scopus 로고
    • A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen
    • 7678422
    • MS Diamond TA Springer 1993 A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen J Cell Biol 120 545 56 7678422
    • (1993) J Cell Biol , vol.120 , pp. 545-56
    • Diamond, M.S.1    Springer, T.A.2
  • 53
    • 0034490559 scopus 로고    scopus 로고
    • Activation-dependent proteolytic degradation of polymorphonuclear CD11b
    • 11122158
    • PC Davey M Zuzel AS Kamiguti JA Hunt KA Aziz 2000 Activation-dependent proteolytic degradation of polymorphonuclear CD11b Br J Haematol 111 934 42 11122158
    • (2000) Br J Haematol , vol.111 , pp. 934-42
    • Davey, P.C.1    Zuzel, M.2    Kamiguti, A.S.3    Hunt, J.A.4    Aziz, K.A.5
  • 54
    • 33751525386 scopus 로고    scopus 로고
    • Intraluminal crawling of neutrophils to emigration sites: A molecularly distinct process from adhesion in the recruitment cascade
    • 17116736
    • M Phillipson B Heit P Colarusso L Liu CM Ballantyne P Kubes 2006 Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade J Exp Med 203 2569 75 17116736
    • (2006) J Exp Med , vol.203 , pp. 2569-75
    • Phillipson, M.1    Heit, B.2    Colarusso, P.3    Liu, L.4    Ballantyne, C.M.5    Kubes, P.6
  • 55
    • 0027530684 scopus 로고
    • The i domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands
    • 7679388
    • MS Diamond J Garcia-Aguilar JK Bickford AL Corbi TA Springer 1993 The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands J Cell Biol 120 1031 43 7679388
    • (1993) J Cell Biol , vol.120 , pp. 1031-43
    • Diamond, M.S.1    Garcia-Aguilar, J.2    Bickford, J.K.3    Corbi, A.L.4    Springer, T.A.5
  • 57
    • 0030854195 scopus 로고    scopus 로고
    • Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules
    • 9330867
    • CG Gahmberg 1997 Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules Curr Opin Cell Biol 9 643 50 9330867
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 643-50
    • Gahmberg, C.G.1
  • 58
    • 0024109978 scopus 로고
    • Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen
    • 3053736
    • DC Altieri R Bader PM Mannucci TS Edgington 1988 Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen J Cell Biol 107 1893 900 3053736
    • (1988) J Cell Biol , vol.107 , pp. 1893-900
    • Altieri, D.C.1    Bader, R.2    Mannucci, P.M.3    Edgington, T.S.4
  • 59
    • 0019953149 scopus 로고
    • Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor
    • 7153706
    • DI Beller TA Springer RD Schreiber 1982 Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor J Exp Med 156 1000 9 7153706
    • (1982) J Exp Med , vol.156 , pp. 1000-9
    • Beller, D.I.1    Springer, T.A.2    Schreiber, R.D.3
  • 60
    • 0034122721 scopus 로고    scopus 로고
    • CR3: A general purpose adhesion-recognition receptor essential for innate immunity
    • 10758405
    • MR Ehlers 2000 CR3: a general purpose adhesion-recognition receptor essential for innate immunity Microbes Infect 2 289 94 10758405
    • (2000) Microbes Infect , vol.2 , pp. 289-94
    • Ehlers, M.R.1
  • 61
    • 0025759969 scopus 로고
    • Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation
    • 1675157
    • MS Diamond DE Staunton SD Marlin TA Springer 1991 Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation Cell 65 961 71 1675157
    • (1991) Cell , vol.65 , pp. 961-71
    • Diamond, M.S.1    Staunton, D.E.2    Marlin, S.D.3    Springer, T.A.4
  • 62
    • 0030007678 scopus 로고    scopus 로고
    • Competition between lymphocyte function-associated antigen 1 (CD11a/CD18) and Mac-1 (CD11b/CD18) for binding to intercellular adhesion molecule-1 (CD54)
    • 8656049
    • M Lub Y van Kooyk CG Figdor 1996 Competition between lymphocyte function-associated antigen 1 (CD11a/CD18) and Mac-1 (CD11b/CD18) for binding to intercellular adhesion molecule-1 (CD54) J Leukoc Biol 59 648 55 8656049
    • (1996) J Leukoc Biol , vol.59 , pp. 648-55
    • Lub, M.1    Van Kooyk, Y.2    Figdor, C.G.3
  • 64
    • 0037073752 scopus 로고    scopus 로고
    • A molecular basis for integrin alphaMbeta 2 ligand binding promiscuity
    • 12377763
    • VP Yakubenko VK Lishko SC Lam TP Ugarova 2002 A molecular basis for integrin alphaMbeta 2 ligand binding promiscuity J Biol Chem 277 48635 42 12377763
    • (2002) J Biol Chem , vol.277 , pp. 48635-42
    • Yakubenko, V.P.1    Lishko, V.K.2    Lam, S.C.3    Ugarova, T.P.4
  • 65
    • 0033594871 scopus 로고    scopus 로고
    • Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi
    • 10387051
    • L Zhang EF Plow 1999 Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi Biochemistry 38 8064 71 10387051
    • (1999) Biochemistry , vol.38 , pp. 8064-71
    • Zhang, L.1    Plow, E.F.2
  • 66
    • 0032908819 scopus 로고    scopus 로고
    • Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domains
    • 10198043
    • KS Weber LB Klickstein C Weber 1999 Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domains Mol Biol Cell 10 861 73 10198043
    • (1999) Mol Biol Cell , vol.10 , pp. 861-73
    • Weber, K.S.1    Klickstein, L.B.2    Weber, C.3
  • 67
    • 29244459407 scopus 로고    scopus 로고
    • Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis
    • 16249234
    • B Heit P Colarusso P Kubes 2005 Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis J Cell Sci 118 5205 20 16249234
    • (2005) J Cell Sci , vol.118 , pp. 5205-20
    • Heit, B.1    Colarusso, P.2    Kubes, P.3
  • 68
    • 27944476021 scopus 로고    scopus 로고
    • Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms
    • 16301335
    • SC Fagerholm TJ Hilden SM Nurmi CG Gahmberg 2005 Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms J Cell Biol 171 705 15 16301335
    • (2005) J Cell Biol , vol.171 , pp. 705-15
    • Fagerholm, S.C.1    Hilden, T.J.2    Nurmi, S.M.3    Gahmberg, C.G.4
  • 69
    • 33751198499 scopus 로고    scopus 로고
    • Alpha-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation
    • 16857989
    • SC Fagerholm M Varis M Stefanidakis TJ Hilden CG Gahmberg 2006 alpha-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation Blood 108 3379 86 16857989
    • (2006) Blood , vol.108 , pp. 3379-86
    • Fagerholm, S.C.1    Varis, M.2    Stefanidakis, M.3    Hilden, T.J.4    Gahmberg, C.G.5
  • 70
    • 0028020563 scopus 로고
    • Functional interaction between the integrin antagonist neutrophil inhibitory factor and the i domain of CD11b/CD18
    • 7929363
    • PJ Muchowski L Zhang ER Chang HR Soule EF Plow M Moyle 1994 Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18 J Biol Chem 269 26419 23 7929363
    • (1994) J Biol Chem , vol.269 , pp. 26419-23
    • Muchowski, P.J.1    Zhang, L.2    Chang, E.R.3    Soule, H.R.4    Plow, E.F.5    Moyle, M.6
  • 71
    • 0032579788 scopus 로고    scopus 로고
    • Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat
    • DOI 10.1016/S0006-8993(97)01503-5, PII S0006899397015035
    • N Jiang M Chopp S Chahwala 1998 Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat Brain Res 788 25 34 9554941 (Pubitemid 28202140)
    • (1998) Brain Research , vol.788 , Issue.1-2 , pp. 25-34
    • Jiang, N.1    Chopp, M.2    Chahwala, S.3
  • 72
    • 0242694372 scopus 로고    scopus 로고
    • Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): An adaptive dose-response study of UK-279, 276 in acute ischemic stroke
    • 14563972
    • M Krams KR Lees W Hacke AP Grieve JM Orgogozo GA Ford 2003 Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): an adaptive dose-response study of UK-279, 276 in acute ischemic stroke Stroke 34 2543 8 14563972
    • (2003) Stroke , vol.34 , pp. 2543-8
    • Krams, M.1    Lees, K.R.2    Hacke, W.3    Grieve, A.P.4    Orgogozo, J.M.5    Ford, G.A.6
  • 73
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. the EPIC investigation
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The EPIC investigation. N Engl J Med. 1994;330:956-61.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 76
    • 0031963688 scopus 로고    scopus 로고
    • Clinical significance of neutrophil adhesion molecules expression after coronary angioplasty on the development of restenosis
    • 9459323
    • T Inoue Y Sakai T Fujito K Hoshi T Hayashi K Takayanagi S Morooka 1998 Clinical significance of neutrophil adhesion molecules expression after coronary angioplasty on the development of restenosis Thromb Haemost 79 54 8 9459323
    • (1998) Thromb Haemost , vol.79 , pp. 54-8
    • Inoue, T.1    Sakai, Y.2    Fujito, T.3    Hoshi, K.4    Hayashi, T.5    Takayanagi, K.6    Morooka, S.7
  • 77
    • 0028967898 scopus 로고
    • Late lumen loss after coronary angioplasty is associated with the activation status of circulating phagocytes before treatment
    • 7867168
    • A Pietersma M Kofflard LE de Wit T Stijnen JF Koster PW Serruys W Sluiter 1995 Late lumen loss after coronary angioplasty is associated with the activation status of circulating phagocytes before treatment Circulation 91 1320 5 7867168
    • (1995) Circulation , vol.91 , pp. 1320-5
    • Pietersma, A.1    Kofflard, M.2    De Wit, L.E.3    Stijnen, T.4    Koster, J.F.5    Serruys, P.W.6    Sluiter, W.7
  • 78
    • 0030221129 scopus 로고    scopus 로고
    • Leukocyte activation with platelet adhesion after coronary angioplasty: A mechanism for recurrent disease?
    • 8800108
    • JK Mickelson NM Lakkis G Villarreal-Levy BJ Hughes CW Smith 1996 Leukocyte activation with platelet adhesion after coronary angioplasty: a mechanism for recurrent disease? J Am Coll Cardiol 28 345 53 8800108
    • (1996) J Am Coll Cardiol , vol.28 , pp. 345-53
    • Mickelson, J.K.1    Lakkis, N.M.2    Villarreal-Levy, G.3    Hughes, B.J.4    Smith, C.W.5
  • 79
    • 0037104688 scopus 로고    scopus 로고
    • The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, alphaMbeta2)
    • 12431477
    • M Schwarz T Nordt C Bode K Peter 2002 The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, alphaMbeta2) Thromb Res 107 121 8 12431477
    • (2002) Thromb Res , vol.107 , pp. 121-8
    • Schwarz, M.1    Nordt, T.2    Bode, C.3    Peter, K.4
  • 80
    • 0032543958 scopus 로고    scopus 로고
    • A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits
    • 9707613
    • C Rogers ER Edelman DI Simon 1998 A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits Proc Natl Acad Sci USA 95 10134 9 9707613
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10134-9
    • Rogers, C.1    Edelman, E.R.2    Simon, D.I.3
  • 81
    • 0023077050 scopus 로고
    • Specificity of membrane complement receptor type three (CR3) for beta-glucans
    • 3040332
    • GD Ross JA Cain BL Myones SL Newman PJ Lachmann 1987 Specificity of membrane complement receptor type three (CR3) for beta-glucans Complement 4 61 74 3040332
    • (1987) Complement , vol.4 , pp. 61-74
    • Ross, G.D.1    Cain, J.A.2    Myones, B.L.3    Newman, S.L.4    Lachmann, P.J.5
  • 82
    • 0030029478 scopus 로고    scopus 로고
    • Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18)
    • 8558003
    • BP Thornton V Vetvicka M Pitman RC Goldman GD Ross 1996 Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18) J Immunol 156 1235 46 8558003
    • (1996) J Immunol , vol.156 , pp. 1235-46
    • Thornton, B.P.1    Vetvicka, V.2    Pitman, M.3    Goldman, R.C.4    Ross, G.D.5
  • 83
    • 0345552244 scopus 로고    scopus 로고
    • The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells
    • 9973505
    • Y Xia V Vetvicka J Yan M Hanikyrova T Mayadas GD Ross 1999 The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells J Immunol 162 2281 90 9973505
    • (1999) J Immunol , vol.162 , pp. 2281-90
    • Xia, Y.1    Vetvicka, V.2    Yan, J.3    Hanikyrova, M.4    Mayadas, T.5    Ross, G.D.6
  • 84
    • 0346690258 scopus 로고    scopus 로고
    • Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells
    • 14695221
    • F Hong RD Hansen J Yan DJ Allendorf JT Baran GR Ostroff GD Ross 2003 Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells Cancer Res 63 9023 31 14695221
    • (2003) Cancer Res , vol.63 , pp. 9023-31
    • Hong, F.1    Hansen, R.D.2    Yan, J.3    Allendorf, D.J.4    Baran, J.T.5    Ostroff, G.R.6    Ross, G.D.7
  • 85
    • 0345281592 scopus 로고    scopus 로고
    • Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18)
    • 10477568
    • J Yan V Vetvicka Y Xia A Coxon MC Carroll TN Mayadas GD Ross 1999 Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18) J Immunol 163 3045 52 10477568
    • (1999) J Immunol , vol.163 , pp. 3045-52
    • Yan, J.1    Vetvicka, V.2    Xia, Y.3    Coxon, A.4    Carroll, M.C.5    Mayadas, T.N.6    Ross, G.D.7
  • 86
    • 34147152321 scopus 로고    scopus 로고
    • Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents
    • 17164347
    • SU Eisenhardt M Schwarz N Schallner J Soosairajah N Bassler D Huang C Bode K Peter 2007 Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents Blood 109 3521 8 17164347
    • (2007) Blood , vol.109 , pp. 3521-8
    • Eisenhardt, S.U.1    Schwarz, M.2    Schallner, N.3    Soosairajah, J.4    Bassler, N.5    Huang, D.6    Bode, C.7    Peter, K.8
  • 87
    • 0028173015 scopus 로고
    • The pathophysiologic role of alpha 4 integrins in vivo
    • 7525645
    • RR Lobb ME Hemler 1994 The pathophysiologic role of alpha 4 integrins in vivo J Clin Invest 94 1722 8 7525645
    • (1994) J Clin Invest , vol.94 , pp. 1722-8
    • Lobb, R.R.1    Hemler, M.E.2
  • 88
    • 34247891506 scopus 로고    scopus 로고
    • Structural basis of integrin regulation and signaling
    • 17201681
    • BH Luo CV Carman TA Springer 2007 Structural basis of integrin regulation and signaling Annu Rev Immunol 25 619 47 17201681
    • (2007) Annu Rev Immunol , vol.25 , pp. 619-47
    • Luo, B.H.1    Carman, C.V.2    Springer, T.A.3
  • 90
  • 92
    • 0032081280 scopus 로고    scopus 로고
    • Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function
    • 9616217
    • F Prosper D Stroncek JB McCarthy CM Verfaillie 1998 Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function J Clin Invest 101 2456 67 9616217
    • (1998) J Clin Invest , vol.101 , pp. 2456-67
    • Prosper, F.1    Stroncek, D.2    McCarthy, J.B.3    Verfaillie, C.M.4
  • 93
    • 0028955748 scopus 로고
    • Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development
    • 7539359
    • JT Yang H Rayburn RO Hynes 1995 Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development Development 121 549 60 7539359
    • (1995) Development , vol.121 , pp. 549-60
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3
  • 95
    • 0346025727 scopus 로고    scopus 로고
    • Junctional adhesion molecules (JAMs): More molecules with dual functions?
    • 14657270
    • K Ebnet A Suzuki S Ohno D Vestweber 2004 Junctional adhesion molecules (JAMs): more molecules with dual functions? J Cell Sci 117 19 29 14657270
    • (2004) J Cell Sci , vol.117 , pp. 19-29
    • Ebnet, K.1    Suzuki, A.2    Ohno, S.3    Vestweber, D.4
  • 99
    • 0036696174 scopus 로고    scopus 로고
    • The immunological synapse: Integrins take the stage
    • 12234366
    • TN Sims ML Dustin 2002 The immunological synapse: integrins take the stage Immunol Rev 186 100 17 12234366
    • (2002) Immunol Rev , vol.186 , pp. 100-17
    • Sims, T.N.1    Dustin, M.L.2
  • 103
    • 0041976960 scopus 로고    scopus 로고
    • Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration
    • 12913113
    • LE Goldfinger J Han WB Kiosses AK Howe MH Ginsberg 2003 Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration J Cell Biol 162 731 41 12913113
    • (2003) J Cell Biol , vol.162 , pp. 731-41
    • Goldfinger, L.E.1    Han, J.2    Kiosses, W.B.3    Howe, A.K.4    Ginsberg, M.H.5
  • 104
    • 0041315888 scopus 로고    scopus 로고
    • Integrin α4β1-dependent cell migration requires both phosphorylation and de-phosphorylation of the a4 cytoplasmic domain
    • 12837751
    • J Han DM Rose DG Woodside LE Goldfinger MH Ginsberg 2003 Integrin α4β1-dependent cell migration requires both phosphorylation and de-phosphorylation of the a4 cytoplasmic domain J Biol Chem 278 34845 53 12837751
    • (2003) J Biol Chem , vol.278 , pp. 34845-53
    • Han, J.1    Rose, D.M.2    Woodside, D.G.3    Goldfinger, L.E.4    Ginsberg, M.H.5
  • 105
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin
    • 1538783
    • TA Yednock C Cannon LC Fritz F Sanchez-Madrid L Steinman N Karin 1992 Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin Nature 356 63 6 1538783
    • (1992) Nature , vol.356 , pp. 63-6
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 107
    • 0028962429 scopus 로고
    • Role of VLA-4 and LFA-1 in allergen-induced airway hyperresponsiveness and lung inflammation in the rat
    • 7881677
    • S Laberge H Rabb TB Issekutz JG Martin 1995 Role of VLA-4 and LFA-1 in allergen-induced airway hyperresponsiveness and lung inflammation in the rat Am J Respir Crit Care Med 151 822 9 7881677
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 822-9
    • Laberge, S.1    Rabb, H.2    Issekutz, T.B.3    Martin, J.G.4
  • 110
    • 0026432216 scopus 로고
    • Inflammatory bowel disease (1)
    • 1881418
    • DK Podolsky 1991 Inflammatory bowel disease (1) N Engl J Med 325 928 37 1881418
    • (1991) N Engl J Med , vol.325 , pp. 928-37
    • Podolsky, D.K.1
  • 111
    • 0036259277 scopus 로고    scopus 로고
    • α4 integrin antagonists
    • 12052218
    • DY Jackson 2002 α4 integrin antagonists Curr Pharm Des 8 1229 53 12052218
    • (2002) Curr Pharm des , vol.8 , pp. 1229-53
    • Jackson, D.Y.1
  • 112
    • 0036174736 scopus 로고    scopus 로고
    • Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases
    • 11857637
    • H Yusuf-Makagiansar ME Anderson TV Yakovleva JS Murray TJ Siahaan 2002 Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases Med Res Rev 22 146 67 11857637
    • (2002) Med Res Rev , vol.22 , pp. 146-67
    • Yusuf-Makagiansar, H.1    Anderson, M.E.2    Yakovleva, T.V.3    Murray, J.S.4    Siahaan, T.J.5
  • 114
    • 0025195762 scopus 로고
    • Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions
    • 2142475
    • ME Hemler MJ Elices C Parker Y Takada 1990 Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions Immunol Rev 114 45 65 2142475
    • (1990) Immunol Rev , vol.114 , pp. 45-65
    • Hemler, M.E.1    Elices, M.J.2    Parker, C.3    Takada, Y.4
  • 115
    • 20844454381 scopus 로고    scopus 로고
    • Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab
    • 15931259
    • L Steinman 2005 Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab Nat Rev Drug Discov 4 510 8 15931259
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 510-8
    • Steinman, L.1
  • 116
    • 22844439662 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
    • 15947079
    • BK Kleinschmidt-DeMasters KL Tyler 2005 Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis N Engl J Med 353 369 74 15947079
    • (2005) N Engl J Med , vol.353 , pp. 369-74
    • Kleinschmidt-Demasters, B.K.1    Tyler, K.L.2
  • 117
    • 22844445230 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
    • 15947078
    • A Langer-Gould SW Atlas AJ Green AW Bollen D Pelletier 2005 Progressive multifocal leukoencephalopathy in a patient treated with natalizumab N Engl J Med 353 375 81 15947078
    • (2005) N Engl J Med , vol.353 , pp. 375-81
    • Langer-Gould, A.1    Atlas, S.W.2    Green, A.J.3    Bollen, A.W.4    Pelletier, D.5
  • 119
    • 2642572579 scopus 로고    scopus 로고
    • New insights into progressive multifocal leukoencephalopathy
    • 15167073
    • IJ Koralnik 2004 New insights into progressive multifocal leukoencephalopathy Curr Opin Neurol 17 365 70 15167073
    • (2004) Curr Opin Neurol , vol.17 , pp. 365-70
    • Koralnik, I.J.1
  • 121
    • 33750525799 scopus 로고    scopus 로고
    • New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation
    • 16870156
    • C Kummer MH Ginsberg 2006 New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation Biochem Pharmacol 72 1460 8 16870156
    • (2006) Biochem Pharmacol , vol.72 , pp. 1460-8
    • Kummer, C.1    Ginsberg, M.H.2
  • 122
    • 0032212143 scopus 로고    scopus 로고
    • Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (αIIbβ3) inhibitors
    • 9787160
    • K Peter M Schwarz J Ylanne B Kohler M Moser T Nordt P Salbach W Kubler C Bode 1998 Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (αIIbβ3) inhibitors Blood 92 3240 9 9787160
    • (1998) Blood , vol.92 , pp. 3240-9
    • Peter, K.1    Schwarz, M.2    Ylanne, J.3    Kohler, B.4    Moser, M.5    Nordt, T.6    Salbach, P.7    Kubler, W.8    Bode, C.9
  • 123
    • 0037118664 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa inhibitors: Recognition of a two-edged sword?
    • 12119257
    • MJ Quinn EF Plow EJ Topol 2002 Platelet glycoprotein IIb/IIIa inhibitors: recognition of a two-edged sword? Circulation 106 379 85 12119257
    • (2002) Circulation , vol.106 , pp. 379-85
    • Quinn, M.J.1    Plow, E.F.2    Topol, E.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.