Diclofenac readily penetrates the cerebrospinal fluid in children

British Journal of Clinical Pharmacology

Volumn 65, Issue 6, 2008, Pages 879-884

  Kokki, Hannu ^a,b,c   Kumpulainen, Elina ^b,c   Laisalmi, Merja ^c   Savolainen, Jouko ^d   Rautio, Jarkko ^b   Lehtonen, Marko ^b  

^a Department of Anaesthesiology and Intensive Care ^*  (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d Oy Fennopharma Ltd   (Finland)

Author keywords

Cerebrospinal fluid; Child; Diclofenac; Infant; Non steroidal anti inflammatory agents; Pharmacokinetics

Indexed keywords

DICLOFENAC; PROSTAGLANDIN SYNTHASE;

AGITATION; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG PENETRATION; DRUG PROTEIN BINDING; ENZYME INHIBITION; FEMALE; HERNIOTOMY; HUMAN; INFANT; INGUINAL HERNIA; MALE; NAUSEA; ORCHIDOPEXY; PAIN; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SHIVERING; SIDE EFFECT; SINGLE DRUG DOSE; VOMITING; WOUND PAIN;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CEREBROSPINAL FLUID; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE INHIBITORS; DICLOFENAC; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAVENOUS; MALE; PAIN, POSTOPERATIVE; STATISTICS AS TOPIC; TIME FACTORS;

EID: 43549084099     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2008.03126.x     Document Type: Article

References (22)