Communication over the Network of Binary Switches Regulates the Activation of A2A Adenosine Receptor

PLoS Computational Biology

Volumn 11, Issue 2, 2015, Pages

  Lee, Yoonji ^a   Choi, Sun ^a   Hyeon, Changbong ^b  

^a Ewha Womans University   (South Korea)

^b School of Computing   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING SITES; CHEMICAL ACTIVATION; LIGANDS; SIGNALING;

ACCURATELY REGULATED; ADENOSINE RECEPTOR; APO-STATE; BINARY SWITCH; BINDING-SITES; DYNAMICS SIMULATION; G PROTEIN COUPLED RECEPTORS; MICROSTATES; RECEPTOR ACTIVITY; STRUCTURAL MOTIFS;

MOLECULAR DYNAMICS;

ADENOSINE A2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; WATER; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; PROTEIN SUBUNIT;

ARTICLE; BINARY SWITCH; BINDING SITE; CONTROLLED STUDY; LIGAND BINDING; MEMBRANE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PROTEIN CONFORMATION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; CHEMISTRY; HYDROGEN BOND; METABOLISM; PROTEIN SUBUNIT;

ADENOSINE A2 RECEPTOR AGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; HYDROGEN BONDING; MOLECULAR DYNAMICS SIMULATION; PROTEIN SUBUNITS; RECEPTOR, ADENOSINE A2A;

EID: 84924405241     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004044     Document Type: Article

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