-
1
-
-
79960181417
-
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
-
A.S. Doré, and N. Robertson F.H. Marshall Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure 19 2011 1283 1293
-
(2011)
Structure
, vol.19
, pp. 1283-1293
-
-
Doré, A.S.1
Robertson, N.2
Marshall, F.H.3
-
2
-
-
78651411166
-
Structure of a nanobody-stabilized active state of the β(2) adrenoceptor
-
S.G.F. Rasmussen, and H.J. Choi B.K. Kobilka Structure of a nanobody-stabilized active state of the β(2) adrenoceptor Nature 469 2011 175 180
-
(2011)
Nature
, vol.469
, pp. 175-180
-
-
Rasmussen, S.G.F.1
Choi, H.J.2
Kobilka, B.K.3
-
3
-
-
80051658642
-
Crystal structure of the β2 adrenergic receptor-Gs protein complex
-
S.G.F. Rasmussen, and B.T. DeVree B.K. Kobilka Crystal structure of the β2 adrenergic receptor-Gs protein complex Nature 477 2011 549 555
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.G.F.1
Devree, B.T.2
Kobilka, B.K.3
-
4
-
-
36448978229
-
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
-
D.M. Rosenbaum, and V. Cherezov B.K. Kobilka GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function Science 318 2007 1266 1273
-
(2007)
Science
, vol.318
, pp. 1266-1273
-
-
Rosenbaum, D.M.1
Cherezov, V.2
Kobilka, B.K.3
-
5
-
-
47949129742
-
Structure of a β1-adrenergic G-protein-coupled receptor
-
T. Warne, and M.J. Serrano-Vega G.F.X. Schertler Structure of a β1-adrenergic G-protein-coupled receptor Nature 454 2008 486 491
-
(2008)
Nature
, vol.454
, pp. 486-491
-
-
Warne, T.1
Serrano-Vega, M.J.2
Schertler, G.F.X.3
-
6
-
-
84867840947
-
Structure of the agonist-bound neurotensin receptor
-
J.F. White, and N. Noinaj R. Grisshammer Structure of the agonist-bound neurotensin receptor Nature 490 2012 508 513
-
(2012)
Nature
, vol.490
, pp. 508-513
-
-
White, J.F.1
Noinaj, N.2
Grisshammer, R.3
-
7
-
-
58149193205
-
Allosteric modulators of GPCRs: A novel approach for the treatment of CNS disorders
-
P.J. Conn, A. Christopoulos, and C.W. Lindsley Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders Nat. Rev. Drug Discov. 8 2009 41 54
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 41-54
-
-
Conn, P.J.1
Christopoulos, A.2
Lindsley, C.W.3
-
8
-
-
84871286519
-
Restructuring G-protein-coupled receptor activation
-
M. Audet, and M. Bouvier Restructuring G-protein-coupled receptor activation Cell 151 2012 14 23
-
(2012)
Cell
, vol.151
, pp. 14-23
-
-
Audet, M.1
Bouvier, M.2
-
9
-
-
33947356279
-
G protein coupled receptor structure and activation
-
B.K. Kobilka G protein coupled receptor structure and activation Biochim. Biophys. Acta 1768 2007 794 807
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 794-807
-
-
Kobilka, B.K.1
-
10
-
-
84879548723
-
The role of ligands on the equilibria between functional states of a G protein-coupled receptor
-
T.H. Kim, and K.Y. Chung R.S. Prosser The role of ligands on the equilibria between functional states of a G protein-coupled receptor J. Am. Chem. Soc. 135 2013 9465 9474
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 9465-9474
-
-
Kim, T.H.1
Chung, K.Y.2
Prosser, R.S.3
-
11
-
-
84873298278
-
The dynamic process of β(2)-adrenergic receptor activation
-
R. Nygaard, and Y. Zou B.K. Kobilka The dynamic process of β(2)-adrenergic receptor activation Cell 152 2013 532 542
-
(2013)
Cell
, vol.152
, pp. 532-542
-
-
Nygaard, R.1
Zou, Y.2
Kobilka, B.K.3
-
12
-
-
0037219686
-
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
-
G.M. Süel, and S.W. Lockless R. Ranganathan Evolutionarily conserved networks of residues mediate allosteric communication in proteins Nat. Struct. Biol. 10 2003 59 69
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 59-69
-
-
Süel, G.M.1
Lockless, S.W.2
Ranganathan, R.3
-
13
-
-
1542379652
-
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions
-
S. Madabushi, and A.K. Gross O. Lichtarge Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions J. Biol. Chem. 279 2004 8126 8132
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8126-8132
-
-
Madabushi, S.1
Gross, A.K.2
Lichtarge, O.3
-
14
-
-
34848882812
-
Signal propagation in proteins and relation to equilibrium fluctuations
-
C. Chennubhotla, and I. Bahar Signal propagation in proteins and relation to equilibrium fluctuations PLOS Comput. Biol. 3 2007 1716 1726
-
(2007)
PLOS Comput. Biol.
, vol.3
, pp. 1716-1726
-
-
Chennubhotla, C.1
Bahar, I.2
-
15
-
-
33646742004
-
Low-frequency normal modes that describe allosteric transitions in biological nanomachines are robust to sequence variations
-
W. Zheng, B.R. Brooks, and D. Thirumalai Low-frequency normal modes that describe allosteric transitions in biological nanomachines are robust to sequence variations Proc. Natl. Acad. Sci. USA 103 2006 7664 7669
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7664-7669
-
-
Zheng, W.1
Brooks, B.R.2
Thirumalai, D.3
-
16
-
-
40549084038
-
Contact rearrangements form coupled networks from local motions in allosteric proteins
-
M.D. Daily, T.J. Upadhyaya, and J.J. Gray Contact rearrangements form coupled networks from local motions in allosteric proteins Proteins 71 2008 455 466
-
(2008)
Proteins
, vol.71
, pp. 455-466
-
-
Daily, M.D.1
Upadhyaya, T.J.2
Gray, J.J.3
-
17
-
-
73449144096
-
Dynamic allostery in the methionine repressor revealed by force distribution analysis
-
W. Stacklies, F. Xia, and F. Gräter Dynamic allostery in the methionine repressor revealed by force distribution analysis PLOS Comput. Biol. 5 2009 e1000574
-
(2009)
PLOS Comput. Biol.
, vol.5
, pp. 1000574
-
-
Stacklies, W.1
Xia, F.2
Gräter, F.3
-
18
-
-
84856514490
-
Detection of allosteric signal transmission by information-theoretic analysis of protein dynamics
-
A. Pandini, and A. Fornili J. Kleinjung Detection of allosteric signal transmission by information-theoretic analysis of protein dynamics FASEB J. 26 2012 868 881
-
(2012)
FASEB J.
, vol.26
, pp. 868-881
-
-
Pandini, A.1
Fornili, A.2
Kleinjung, J.3
-
20
-
-
73349111643
-
Quantifying correlations between allosteric sites in thermodynamic ensembles
-
C.L. McClendon, and G. Friedland M.P. Jacobson Quantifying correlations between allosteric sites in thermodynamic ensembles J. Chem. Theory Comput. 5 2009 2486 2502
-
(2009)
J. Chem. Theory Comput.
, vol.5
, pp. 2486-2502
-
-
McClendon, C.L.1
Friedland, G.2
Jacobson, M.P.3
-
22
-
-
84879707465
-
Activation and dynamic network of the M2 muscarinic receptor
-
Y. Miao, and S.E. Nichols J.A. McCammon Activation and dynamic network of the M2 muscarinic receptor Proc. Natl. Acad. Sci. USA 110 2013 10982 10987
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10982-10987
-
-
Miao, Y.1
Nichols, S.E.2
McCammon, J.A.3
-
23
-
-
63849294621
-
Identification of two distinct inactive conformations of the β2-adrenergic receptor reconciles structural and biochemical observations
-
R.O. Dror, and D.H. Arlow D.E. Shaw Identification of two distinct inactive conformations of the β2-adrenergic receptor reconciles structural and biochemical observations Proc. Natl. Acad. Sci. USA 106 2009 4689 4694
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4689-4694
-
-
Dror, R.O.1
Arlow, D.H.2
Shaw, D.E.3
-
25
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
A.D. MacKerell, and D. Bashford M. Karplus All-atom empirical potential for molecular modeling and dynamics studies of proteins J. Phys. Chem. B 102 1998 3586 3616
-
(1998)
J. Phys. Chem. B
, vol.102
, pp. 3586-3616
-
-
Mackerell, A.D.1
Bashford, D.2
Karplus, M.3
-
26
-
-
34147120474
-
A note on two problems in connexion with graphs
-
E.W. Dijkstra A note on two problems in connexion with graphs Numer. Math. 1 1959 269 271
-
(1959)
Numer. Math.
, vol.1
, pp. 269-271
-
-
Dijkstra, E.W.1
-
27
-
-
79953234218
-
Crystal structure of metarhodopsin II
-
H.W. Choe, and Y.J. Kim O.P. Ernst Crystal structure of metarhodopsin II Nature 471 2011 651 655
-
(2011)
Nature
, vol.471
, pp. 651-655
-
-
Choe, H.W.1
Kim, Y.J.2
Ernst, O.P.3
-
28
-
-
80052038573
-
β-Arrestin-mediated receptor trafficking and signal transduction
-
S.K. Shenoy, and R.J. Lefkowitz β-Arrestin-mediated receptor trafficking and signal transduction Trends Pharmacol. Sci. 32 2011 521 533
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 521-533
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
29
-
-
38949158505
-
Conformational thermostabilization of the β1-adrenergic receptor in a detergent-resistant form
-
M.J. Serrano-Vega, and F. Magnani C.G. Tate Conformational thermostabilization of the β1-adrenergic receptor in a detergent-resistant form Proc. Natl. Acad. Sci. USA 105 2008 877 882
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 877-882
-
-
Serrano-Vega, M.J.1
Magnani, F.2
Tate, C.G.3
-
30
-
-
79956124396
-
Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor
-
G. Lebon, and K. Bennett C.G. Tate Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor J. Mol. Biol. 409 2011 298 310
-
(2011)
J. Mol. Biol.
, vol.409
, pp. 298-310
-
-
Lebon, G.1
Bennett, K.2
Tate, C.G.3
-
31
-
-
77957055780
-
[19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors
-
J. Ballesteros, and H. Weinstein [19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors Methods Neurosci. 25 1995 366 428
-
(1995)
Methods Neurosci.
, vol.25
, pp. 366-428
-
-
Ballesteros, J.1
Weinstein, H.2
-
32
-
-
84861961427
-
Structural basis for allosteric regulation of GPCRs by sodium ions
-
W. Liu, and E. Chun R.C. Stevens Structural basis for allosteric regulation of GPCRs by sodium ions Science 337 2012 232 236
-
(2012)
Science
, vol.337
, pp. 232-236
-
-
Liu, W.1
Chun, E.2
Stevens, R.C.3
-
33
-
-
44649172481
-
A specific cholesterol binding site is established by the 2.8 A structure of the human β2-adrenergic receptor
-
M.A. Hanson, and V. Cherezov R.C. Stevens A specific cholesterol binding site is established by the 2.8 A structure of the human β2-adrenergic receptor Structure 16 2008 897 905
-
(2008)
Structure
, vol.16
, pp. 897-905
-
-
Hanson, M.A.1
Cherezov, V.2
Stevens, R.C.3
-
34
-
-
0036239236
-
Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation
-
P.J. Greasley, and F. Fanelli S. Cotecchia Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation Mol. Pharmacol. 61 2002 1025 1032
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1025-1032
-
-
Greasley, P.J.1
Fanelli, F.2
Cotecchia, S.3
-
35
-
-
57649138443
-
Dual role of the β2-adrenergic receptor C terminus for the binding of β-arrestin and receptor internalization
-
C. Krasel, and U. Zabel M.J. Lohse Dual role of the β2-adrenergic receptor C terminus for the binding of β-arrestin and receptor internalization J. Biol. Chem. 283 2008 31840 31848
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31840-31848
-
-
Krasel, C.1
Zabel, U.2
Lohse, M.J.3
-
36
-
-
0024519931
-
Structural basis of β-adrenergic receptor function
-
C.D. Strader, I.S. Sigal, and R.A. Dixon Structural basis of β-adrenergic receptor function FASEB J. 3 1989 1825 1832
-
(1989)
FASEB J.
, vol.3
, pp. 1825-1832
-
-
Strader, C.D.1
Sigal, I.S.2
Dixon, R.A.3
-
37
-
-
0030577241
-
Amino acids of the α1β-adrenergic receptor involved in agonist binding: Differences in docking catecholamines to receptor subtypes
-
A. Cavalli, and F. Fanelli S. Cotecchia Amino acids of the α1β-adrenergic receptor involved in agonist binding: differences in docking catecholamines to receptor subtypes FEBS Lett. 399 1996 9 13
-
(1996)
FEBS Lett.
, vol.399
, pp. 9-13
-
-
Cavalli, A.1
Fanelli, F.2
Cotecchia, S.3
-
38
-
-
0032586276
-
Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human β2-adrenoceptor contributes to agonist binding and receptor activation
-
T. Sato, and H. Kobayashi H. Kurose Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human β2-adrenoceptor contributes to agonist binding and receptor activation Br. J. Pharmacol. 128 1999 272 274
-
(1999)
Br. J. Pharmacol.
, vol.128
, pp. 272-274
-
-
Sato, T.1
Kobayashi, H.2
Kurose, H.3
-
39
-
-
0034529234
-
The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the β2-adrenergic receptor
-
G. Liapakis, and J.A. Ballesteros J.A. Javitch The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the β2-adrenergic receptor J. Biol. Chem. 275 2000 37779 37788
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37779-37788
-
-
Liapakis, G.1
Ballesteros, J.A.2
Javitch, J.A.3
-
41
-
-
84872024032
-
Emerging opportunities for allosteric modulation of G-protein coupled receptors
-
C.I.A. Wang, and R.J. Lewis Emerging opportunities for allosteric modulation of G-protein coupled receptors Biochem. Pharmacol. 85 2013 153 162
-
(2013)
Biochem. Pharmacol.
, vol.85
, pp. 153-162
-
-
Wang, C.I.A.1
Lewis, R.J.2
-
42
-
-
77955249382
-
Mapping the druggable allosteric space of G-protein coupled receptors: A fragment-based molecular dynamics approach
-
A. Ivetac, and J.A. McCammon Mapping the druggable allosteric space of G-protein coupled receptors: a fragment-based molecular dynamics approach Chem. Biol. Drug Des. 76 2010 201 217
-
(2010)
Chem. Biol. Drug Des.
, vol.76
, pp. 201-217
-
-
Ivetac, A.1
McCammon, J.A.2
-
43
-
-
84889564886
-
Activation and allosteric modulation of a muscarinic acetylcholine receptor
-
A.C. Kruse, and A.M. Ring B.K. Kobilka Activation and allosteric modulation of a muscarinic acetylcholine receptor Nature 504 2013 101 106
-
(2013)
Nature
, vol.504
, pp. 101-106
-
-
Kruse, A.C.1
Ring, A.M.2
Kobilka, B.K.3
-
44
-
-
0037414774
-
Identification of an allosteric binding site for Zn2+ on the β2 adrenergic receptor
-
G. Swaminath, T.W. Lee, and B. Kobilka Identification of an allosteric binding site for Zn2+ on the β2 adrenergic receptor J. Biol. Chem. 278 2003 352 356
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 352-356
-
-
Swaminath, G.1
Lee, T.W.2
Kobilka, B.3
-
45
-
-
84889573352
-
The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor
-
H. Gutiérrez-de-Terán, and A. Massink R.C. Stevens The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor Structure 21 2013 2175 2185
-
(2013)
Structure
, vol.21
, pp. 2175-2185
-
-
Gutiérrez-De-Terán, H.1
Massink, A.2
Stevens, R.C.3
-
46
-
-
80051769266
-
The role of conformational ensembles in ligand recognition in G-protein coupled receptors
-
M.J. Niesen, S. Bhattacharya, and N. Vaidehi The role of conformational ensembles in ligand recognition in G-protein coupled receptors J. Am. Chem. Soc. 133 2011 13197 13204
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 13197-13204
-
-
Niesen, M.J.1
Bhattacharya, S.2
Vaidehi, N.3
-
47
-
-
0024382126
-
Site-directed mutagenesis of β-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation
-
C.M. Fraser Site-directed mutagenesis of β-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation J. Biol. Chem. 264 1989 9266 9270
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 9266-9270
-
-
Fraser, C.M.1
-
48
-
-
84862777405
-
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
-
K. Haga, and A.C. Kruse T. Kobayashi Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist Nature 482 2012 547 551
-
(2012)
Nature
, vol.482
, pp. 547-551
-
-
Haga, K.1
Kruse, A.C.2
Kobayashi, T.3
-
49
-
-
0029589916
-
Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation
-
J. Liu, and B.R. Conklin J. Wess Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation Proc. Natl. Acad. Sci. USA 92 1995 11642 11646
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11642-11646
-
-
Liu, J.1
Conklin, B.R.2
Wess, J.3
-
50
-
-
84867010308
-
The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling
-
A. Bock, and N. Merten K. Mohr The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling Nat. Commun. 3 2012 1044
-
(2012)
Nat. Commun.
, vol.3
, pp. 1044
-
-
Bock, A.1
Merten, N.2
Mohr, K.3
-
51
-
-
73849149844
-
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
-
M.P. Bokoch, and Y. Zou B.K. Kobilka Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor Nature 463 2010 108 112
-
(2010)
Nature
, vol.463
, pp. 108-112
-
-
Bokoch, M.P.1
Zou, Y.2
Kobilka, B.K.3
-
52
-
-
84863115467
-
Structure and dynamics of the M3 muscarinic acetylcholine receptor
-
A.C. Kruse, and J. Hu B.K. Kobilka Structure and dynamics of the M3 muscarinic acetylcholine receptor Nature 482 2012 552 556
-
(2012)
Nature
, vol.482
, pp. 552-556
-
-
Kruse, A.C.1
Hu, J.2
Kobilka, B.K.3
-
53
-
-
84887620421
-
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
-
R.O. Dror, and H.F. Green D.E. Shaw Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs Nature 503 2013 295 299
-
(2013)
Nature
, vol.503
, pp. 295-299
-
-
Dror, R.O.1
Green, H.F.2
Shaw, D.E.3
-
54
-
-
0028793627
-
The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the β2-adrenergic receptor
-
L.S. Barak, and L. Ménard M.G. Caron The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the β2-adrenergic receptor Biochemistry 34 1995 15407 15414
-
(1995)
Biochemistry
, vol.34
, pp. 15407-15414
-
-
Barak, L.S.1
Ménard, L.2
Caron, M.G.3
-
55
-
-
1342329641
-
Random mutagenesis of the human adenosine A2B receptor followed by growth selection in yeast. Identification of constitutively active and gain of function mutations
-
M.W. Beukers, and J. van Oppenraaij A.P. IJzerman Random mutagenesis of the human adenosine A2B receptor followed by growth selection in yeast. Identification of constitutively active and gain of function mutations Mol. Pharmacol. 65 2004 702 710
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 702-710
-
-
Beukers, M.W.1
Van Oppenraaij, J.2
Ijzerman, A.P.3
-
56
-
-
0031939636
-
The role of the seventh transmembrane region in high affinity binding of a β2-selective agonist TA-2005
-
H. Kikkawa, and M. Isogaya H. Kurose The role of the seventh transmembrane region in high affinity binding of a β2-selective agonist TA-2005 Mol. Pharmacol. 53 1998 128 134
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 128-134
-
-
Kikkawa, H.1
Isogaya, M.2
Kurose, H.3
-
57
-
-
65549109031
-
Configurational entropy in protein-peptide binding: Computational study of Tsg101 ubiquitin E2 variant domain with an HIV-derived PTAP nonapeptide
-
B.J. Killian, and J.Y. Kravitz M.K. Gilson Configurational entropy in protein-peptide binding: computational study of Tsg101 ubiquitin E2 variant domain with an HIV-derived PTAP nonapeptide J. Mol. Biol. 389 2009 315 335
-
(2009)
J. Mol. Biol.
, vol.389
, pp. 315-335
-
-
Killian, B.J.1
Kravitz, J.Y.2
Gilson, M.K.3
-
58
-
-
0026639831
-
Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor. Role of conserved cysteines in receptor function
-
T.M. Savarese, C.D. Wang, and C.M. Fraser Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor. Role of conserved cysteines in receptor function J. Biol. Chem. 267 1992 11439 11448
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11439-11448
-
-
Savarese, T.M.1
Wang, C.D.2
Fraser, C.M.3
-
59
-
-
84856043672
-
The mathematical theory of communication
-
C.E. Shannon The mathematical theory of communication Bell Syst. Tech. J. 27 1948 379 423
-
(1948)
Bell Syst. Tech. J.
, vol.27
, pp. 379-423
-
-
Shannon, C.E.1
-
60
-
-
0042526388
-
The mutual information: Detecting and evaluating dependencies between variables
-
R. Steuer, and J. Kurths J. Selbig The mutual information: detecting and evaluating dependencies between variables Bioinformatics 18 Suppl 2 2002 S231 S240
-
(2002)
Bioinformatics
, vol.18
, Issue.SUPPL. 2
-
-
Steuer, R.1
Kurths, J.2
Selbig, J.3
-
61
-
-
0036128982
-
β (1)-Selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4- dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for β (1)-selective binding in resting and active states
-
Y. Sugimoto, and R. Fujisawa H. Kurose β (1)-Selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for β (1)-selective binding in resting and active states J. Pharmacol. Exp. Ther. 301 2002 51 58
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 51-58
-
-
Sugimoto, Y.1
Fujisawa, R.2
Kurose, H.3
-
62
-
-
0034465336
-
Constitutive activation of G protein-coupled receptors as a result of selective substitution of a conserved leucine residue in transmembrane helix III
-
Y.X. Tao, and A.N. Abell D.L. Segaloff Constitutive activation of G protein-coupled receptors as a result of selective substitution of a conserved leucine residue in transmembrane helix III Mol. Endocrinol. 14 2000 1272 1282
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1272-1282
-
-
Tao, Y.X.1
Abell, A.N.2
Segaloff, D.L.3
-
63
-
-
78651405537
-
The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor
-
T. Warne, and R. Moukhametzianov C.G. Tate The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor Nature 469 2011 241 244
-
(2011)
Nature
, vol.469
, pp. 241-244
-
-
Warne, T.1
Moukhametzianov, R.2
Tate, C.G.3
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