메뉴 건너뛰기




Volumn 180, Issue 1, 2015, Pages 58-69

Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis

Author keywords

Graves' disease; Hashimoto's thyroiditis; Interleukins; Regulatory T cells; Th17 cells

Indexed keywords

CD4 ANTIGEN; CD45R0 ANTIGEN; CD45RA ANTIGEN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 6; THYROGLOBULIN; THYROID PEROXIDASE; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; AUTOANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; INTERLEUKIN 10; IODIDE PEROXIDASE; IRON BINDING PROTEIN; ISOPROTEIN; LEUKOCYTE ANTIGEN; LIPOPOLYSACCHARIDE; TGFB1 PROTEIN, HUMAN; TPO PROTEIN, HUMAN;

EID: 84924333596     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12557     Document Type: Article
Times cited : (37)

References (59)
  • 1
    • 0035555276 scopus 로고    scopus 로고
    • Determinants of autoimmune thyroid disease
    • Weetman AP. Determinants of autoimmune thyroid disease. Nat Immunol 2001; 2:769-770.
    • (2001) Nat Immunol , vol.2 , pp. 769-770
    • Weetman, A.P.1
  • 2
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-2357.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 3
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 4
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17:138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 5
    • 0023637828 scopus 로고
    • Enhanced production of gamma-interferon by thyroid-derived T cell clones from patients with Hashimoto's thyroiditis
    • Del Prete GF, Tiri A, Mariotti S, Pinchera A, Ricci M, Romagnani S. Enhanced production of gamma-interferon by thyroid-derived T cell clones from patients with Hashimoto's thyroiditis. Clin Exp Immunol 1987; 69:323-331.
    • (1987) Clin Exp Immunol , vol.69 , pp. 323-331
    • Del Prete, G.F.1    Tiri, A.2    Mariotti, S.3    Pinchera, A.4    Ricci, M.5    Romagnani, S.6
  • 6
    • 0032987199 scopus 로고    scopus 로고
    • Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro
    • Guo J, Rapoport B, McLachlan SM. Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro. Autoimmunity 1999; 30:1-9.
    • (1999) Autoimmunity , vol.30 , pp. 1-9
    • Guo, J.1    Rapoport, B.2    McLachlan, S.M.3
  • 8
    • 33744995604 scopus 로고    scopus 로고
    • + T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease
    • + T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease. J Clin Immunol 2006; 26:126-137.
    • (2006) J Clin Immunol , vol.26 , pp. 126-137
    • Nielsen, C.H.1    Moeller, A.C.2    Hegedus, L.3    Bendtzen, K.4    Leslie, R.G.Q.5
  • 9
    • 4444325343 scopus 로고    scopus 로고
    • Functional lymphocyte subset assessment of the Th1/Th2 profile in patients with autoimmune thyroiditis by flow cytometric analysis of peripheral lymphocytes
    • Colin IM, Isaac J, Dupret IP, Ledant T, D'Hautcourt JL. Functional lymphocyte subset assessment of the Th1/Th2 profile in patients with autoimmune thyroiditis by flow cytometric analysis of peripheral lymphocytes. J Biol Regul Homeost Agents 2004; 18:72-76.
    • (2004) J Biol Regul Homeost Agents , vol.18 , pp. 72-76
    • Colin, I.M.1    Isaac, J.2    Dupret, I.P.3    Ledant, T.4    D'Hautcourt, J.L.5
  • 10
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin-17 producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR etal. Interleukin-17 producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6:1123-1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 12
    • 42449129284 scopus 로고    scopus 로고
    • Th17 cells: a third subset of CD4+ T effector cells involved in organ-specific autoimmunity
    • Kurts C. Th17 cells: a third subset of CD4+ T effector cells involved in organ-specific autoimmunity. Nephrol Dial Transplant 2008; 23:816-819.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 816-819
    • Kurts, C.1
  • 13
    • 77955298749 scopus 로고    scopus 로고
    • Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto's thyroiditis
    • Shi Y, Wang H, Su Z etal. Differentiation imbalance of Th1/Th17 in peripheral blood mononuclear cells might contribute to pathogenesis of Hashimoto's thyroiditis. Scand J Immunol 2010; 72:250-255.
    • (2010) Scand J Immunol , vol.72 , pp. 250-255
    • Shi, Y.1    Wang, H.2    Su, Z.3
  • 14
    • 67650345273 scopus 로고    scopus 로고
    • Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease
    • Nanba T, Watanabe M, Inoue N, Iwatani Y. Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease. Thyroid 2009; 19:495-501.
    • (2009) Thyroid , vol.19 , pp. 495-501
    • Nanba, T.1    Watanabe, M.2    Inoue, N.3    Iwatani, Y.4
  • 16
    • 84880055907 scopus 로고    scopus 로고
    • A high frequency of circulating Th22 and Th17 cells in patients with new onset Graves' disease
    • Peng D, Xu B, Wang Y, Guo H, Jiang Y. A high frequency of circulating Th22 and Th17 cells in patients with new onset Graves' disease. PLOS ONE 2013; 8:e68446.
    • (2013) PLOS ONE , vol.8 , pp. e68446
    • Peng, D.1    Xu, B.2    Wang, Y.3    Guo, H.4    Jiang, Y.5
  • 17
    • 67349151620 scopus 로고    scopus 로고
    • + regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen
    • + regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen. J Autoimmun 2009; 33:68-76.
    • (2009) J Autoimmun , vol.33 , pp. 68-76
    • Morris, G.P.1    Brown, N.K.2    Kong, Y.M.3
  • 20
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 22
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 26
    • 70049118519 scopus 로고    scopus 로고
    • Regulatory T cell suppression is potentiated by Target T cells in a cell contact, IL-35- and IL-10-dependent manner
    • Collison LW, Pillai MR, Chaturvedi V, Vignali DAA. Regulatory T cell suppression is potentiated by Target T cells in a cell contact, IL-35- and IL-10-dependent manner. J Immunol 2009; 182:6121-6128.
    • (2009) J Immunol , vol.182 , pp. 6121-6128
    • Collison, L.W.1    Pillai, M.R.2    Chaturvedi, V.3    Vignali, D.A.A.4
  • 28
    • 84881453041 scopus 로고    scopus 로고
    • Impairment of regulatory T-cell function in autoimmune thyroid disease
    • Glick AB, Wodzinski A, Pingfu F, Levine AD, Wald DN. Impairment of regulatory T-cell function in autoimmune thyroid disease. Thyroid 2013; 23:871-878.
    • (2013) Thyroid , vol.23 , pp. 871-878
    • Glick, A.B.1    Wodzinski, A.2    Pingfu, F.3    Levine, A.D.4    Wald, D.N.5
  • 30
    • 33846204725 scopus 로고    scopus 로고
    • Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease
    • Nielsen CH, Hegedus L, Rieneck K, Moeller AC, Leslie RGQ, Bendtzen K. Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease. Clin Exp Immunol 2007; 147:287-295.
    • (2007) Clin Exp Immunol , vol.147 , pp. 287-295
    • Nielsen, C.H.1    Hegedus, L.2    Rieneck, K.3    Moeller, A.C.4    Leslie, R.G.Q.5    Bendtzen, K.6
  • 31
    • 73949121456 scopus 로고    scopus 로고
    • + T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes
    • + T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes. Immunology 2009; 129:291-299.
    • (2009) Immunology , vol.129 , pp. 291-299
    • Nielsen, C.H.1    Galdiers, M.P.2    Hedegaard, C.J.3    Leslie, R.G.Q.4
  • 32
    • 84864825042 scopus 로고    scopus 로고
    • B-cell exposure to self-antigen induces IL-10 producing B cells as well as IL-6 and TNF-α producing B-cell subsets in healthy humans
    • Langkjær A, Kristensen B, Hansen BF, Schultz H, Hegedus L, Nielsen CH. B-cell exposure to self-antigen induces IL-10 producing B cells as well as IL-6 and TNF-α producing B-cell subsets in healthy humans. Clin Immunol 2012; 145:1-10.
    • (2012) Clin Immunol , vol.145 , pp. 1-10
    • Langkjær, A.1    Kristensen, B.2    Hansen, B.F.3    Schultz, H.4    Hegedus, L.5    Nielsen, C.H.6
  • 33
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGF-beta are required for differentiation of human T(H)17 cell
    • Yang L, Anderson DE, Baecher-Allan C etal. IL-21 and TGF-beta are required for differentiation of human T(H)17 cell. Nature 2008; 454:350-352.
    • (2008) Nature , vol.454 , pp. 350-352
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3
  • 34
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 2007; 8:942-949.
    • (2007) Nat Immunol , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 35
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammaT
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammaT. Nat Immunol 2008; 9:641-649.
    • (2008) Nat Immunol , vol.9 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 36
    • 32244442562 scopus 로고    scopus 로고
    • TGF-beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGF-beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006; 24:179-189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 37
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W etal. Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature 2006; 441:235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 38
    • 66649115650 scopus 로고    scopus 로고
    • Human memory FOXP3 Tregs secrete IL-17 ex vivo and constitutively express the Th17 lineage-specific transcription factor RORgammaT
    • Ayyoub M, Deknuydt F, Raimbaud I etal. Human memory FOXP3 Tregs secrete IL-17 ex vivo and constitutively express the Th17 lineage-specific transcription factor RORgammaT. Proc Natl Acad Sci USA 2009; 106:8635-8640.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8635-8640
    • Ayyoub, M.1    Deknuydt, F.2    Raimbaud, I.3
  • 40
    • 65549088243 scopus 로고    scopus 로고
    • IL-17-producing human peripheral regulatory T cells retain suppressive function
    • Beriou G, Costantino CM, Ashley CW etal. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 2009; 113:4240-4249.
    • (2009) Blood , vol.113 , pp. 4240-4249
    • Beriou, G.1    Costantino, C.M.2    Ashley, C.W.3
  • 41
    • 56349109500 scopus 로고    scopus 로고
    • Role of Th1 and Th17 cells in organ-specific autoimmunity
    • Dardalhon V, Korn T, Kuchroo VK, Anderson AC. Role of Th1 and Th17 cells in organ-specific autoimmunity. J Autoimmun 2008; 31:252-256.
    • (2008) J Autoimmun , vol.31 , pp. 252-256
    • Dardalhon, V.1    Korn, T.2    Kuchroo, V.K.3    Anderson, A.C.4
  • 42
    • 36248965294 scopus 로고    scopus 로고
    • TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
    • McGreachy MJ, Bak-Jensen KS, Chen Y etal. TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology. Nat Immunol 2007; 8:1390-1397.
    • (2007) Nat Immunol , vol.8 , pp. 1390-1397
    • McGreachy, M.J.1    Bak-Jensen, K.S.2    Chen, Y.3
  • 43
    • 84860241847 scopus 로고    scopus 로고
    • Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
    • Zielinski CE, Mele F, Aschenbrenner D etal. Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. Nature 2012; 484:514-519.
    • (2012) Nature , vol.484 , pp. 514-519
    • Zielinski, C.E.1    Mele, F.2    Aschenbrenner, D.3
  • 44
    • 51249090471 scopus 로고    scopus 로고
    • T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis
    • Hedegaard CJ, Krakauer M, Bendtzen K, Lund H, Sellebjerg F, Nielsen CH. T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis. Immunology 2008; 125:161-169.
    • (2008) Immunology , vol.125 , pp. 161-169
    • Hedegaard, C.J.1    Krakauer, M.2    Bendtzen, K.3    Lund, H.4    Sellebjerg, F.5    Nielsen, C.H.6
  • 46
    • 77954866455 scopus 로고    scopus 로고
    • Expression of full-length and splice forms of FOXP3 in rheumatoid arthritis
    • Ryder LR, Woetmann A, Madsen HO etal. Expression of full-length and splice forms of FOXP3 in rheumatoid arthritis. Scand J Rheumatol 2010; 39:279-286.
    • (2010) Scand J Rheumatol , vol.39 , pp. 279-286
    • Ryder, L.R.1    Woetmann, A.2    Madsen, H.O.3
  • 47
    • 84859953961 scopus 로고    scopus 로고
    • + T cells in rheumatoid arthritis and psoriatic arthritis
    • + T cells in rheumatoid arthritis and psoriatic arthritis. APMIS 2011; 120:387-396.
    • (2011) APMIS , vol.120 , pp. 387-396
    • Ryder, L.R.1    Bartels, E.M.2    Woetmann, A.3
  • 48
    • 63449129385 scopus 로고    scopus 로고
    • Systematic method for determining an ideal housekeeping gene for real-time PCR analysis
    • Mane VP, Heuer MA, Hillyer P, Navarro MB, Rabin RL. Systematic method for determining an ideal housekeeping gene for real-time PCR analysis. J Biomol Tech 2008; 19:342-347.
    • (2008) J Biomol Tech , vol.19 , pp. 342-347
    • Mane, V.P.1    Heuer, M.A.2    Hillyer, P.3    Navarro, M.B.4    Rabin, R.L.5
  • 49
    • 77954688261 scopus 로고    scopus 로고
    • Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization
    • McAleer JP, Liu B, Li Z etal. Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization. J Leukoc Biol 2010; 88:21-31.
    • (2010) J Leukoc Biol , vol.88 , pp. 21-31
    • McAleer, J.P.1    Liu, B.2    Li, Z.3
  • 50
    • 18244378309 scopus 로고    scopus 로고
    • Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX)
    • Kobayashi I, Shiari R, Yamada M etal. Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX). J Med Genet 2001; 38:874-876.
    • (2001) J Med Genet , vol.38 , pp. 874-876
    • Kobayashi, I.1    Shiari, R.2    Yamada, M.3
  • 51
    • 34948875308 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells
    • Torgerson TR, Ochs HD. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J Allergy Clin Immunol 2007; 120:744-750.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 744-750
    • Torgerson, T.R.1    Ochs, H.D.2
  • 52
    • 57849154832 scopus 로고    scopus 로고
    • Malignant Tregs express low molecular splice forms of FOXP3 in Sezary syndrome
    • Krejsgaard T, Gjerdrum LM, Ralfkiaer E etal. Malignant Tregs express low molecular splice forms of FOXP3 in Sezary syndrome. Leukemia 2008; 22:2230-2239.
    • (2008) Leukemia , vol.22 , pp. 2230-2239
    • Krejsgaard, T.1    Gjerdrum, L.M.2    Ralfkiaer, E.3
  • 53
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci USA 2005; 102:5138-5143.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 54
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3
    • Du J, Huang C, Zhou B, Ziegler SF. Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3. J Immunol 2008; 180:4785-4792.
    • (2008) J Immunol , vol.180 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3    Ziegler, S.F.4
  • 55
    • 43449135305 scopus 로고    scopus 로고
    • TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
    • Zhou L, Lopes JE, Chong MM etal. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 2008; 453:236-240.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1    Lopes, J.E.2    Chong, M.M.3
  • 57
    • 0019760458 scopus 로고
    • Inhibition of immunoglobulin-secreting cells by antithyroid cells
    • Weiss I, Davis TF. Inhibition of immunoglobulin-secreting cells by antithyroid cells. J Clin Endocrinol Metab 1981; 53:1223-1228.
    • (1981) J Clin Endocrinol Metab , vol.53 , pp. 1223-1228
    • Weiss, I.1    Davis, T.F.2
  • 58
    • 40849147275 scopus 로고    scopus 로고
    • Thionamides inhibit the transcription factor nuclear factor-κB by suppression of Rac1 and inhibitor of κB kinase α
    • Humar M, Dohrmann H, Stein P etal. Thionamides inhibit the transcription factor nuclear factor-κB by suppression of Rac1 and inhibitor of κB kinase α. J Pharmacol Exp Ther 2008; 324:1037-1044.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 1037-1044
    • Humar, M.1    Dohrmann, H.2    Stein, P.3
  • 59
    • 0035036186 scopus 로고    scopus 로고
    • The immunomodulatory effects of anti-thyroid drugs are mediated via actions on thyroid cells, affecting thyrocyte-immunocyte signaling: a review
    • Volpe R. The immunomodulatory effects of anti-thyroid drugs are mediated via actions on thyroid cells, affecting thyrocyte-immunocyte signaling: a review. Curr Pharm Des 2001; 7:451-460.
    • (2001) Curr Pharm Des , vol.7 , pp. 451-460
    • Volpe, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.