Naturally-existing CD4+CD25+Foxp3+ regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen

Journal of Autoimmunity

Volumn 33, Issue 1, 2009, Pages 68-76

  Morris, Gerald P ^a   Brown, Nicholas K ^a   Kong, Yi chi M ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmune thyroiditis; CTLA 4; Regulatory T cells; Self tolerance; Tolerance induction

Indexed keywords

AUTOANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; THYROGLOBULIN; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE THYROIDITIS; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENETIC SUSCEPTIBILITY; HASHIMOTO DISEASE; HISTOPATHOLOGY; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD4; AUTOANTIGENS; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HASHIMOTO DISEASE; HUMANS; IMMUNIZATION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED CBA; SELF TOLERANCE; T-LYMPHOCYTES, REGULATORY; THYROGLOBULIN; THYROIDITIS, AUTOIMMUNE;

EID: 67349151620     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2009.03.010     Document Type: Article

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