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Volumn 5, Issue 4, 2015, Pages 357-370

Off to the organelles - killing cancer cells with targeted gold nanoparticles

Author keywords

AuNPs; Cancer cell imaging; Gold nanoparticles

Indexed keywords

DOXORUBICIN; EPIDERMAL GROWTH FACTOR; GLUCOCORTICOID RECEPTOR; GOLD NANOPARTICLE; MACROGOL; DRUG CARRIER; GOLD; NANOPARTICLE;

EID: 84924325424     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.10657     Document Type: Review
Times cited : (144)

References (146)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg Robert A. Hallmarks of cancer: The next generation. Cell. 2011; 144: 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg Robert, A.2
  • 2
    • 84892963544 scopus 로고    scopus 로고
    • Cancer therapy: Targeting mitochondria and other sub-cellular organelles
    • Ubah OC, Wallace HM. Cancer therapy: Targeting mitochondria and other sub-cellular organelles. Curr Pharm Des. 2014; 20: 201-22.
    • (2014) Curr Pharm Des , vol.20 , pp. 201-222
    • Ubah, O.C.1    Wallace, H.M.2
  • 3
    • 84901610137 scopus 로고    scopus 로고
    • Nanotechnology: Deliver on a promise
    • Wright J. Nanotechnology: Deliver on a promise. Nature. 2014; 509: S58-S9.
    • (2014) Nature , vol.509 , pp. S58-S59
    • Wright, J.1
  • 5
    • 79959494450 scopus 로고    scopus 로고
    • Gold nanoparticles and quantum dots for bioimaging
    • Hutter E, Maysinger D. Gold nanoparticles and quantum dots for bioimaging. Microsc Res Tech. 2011; 74: 592-604.
    • (2011) Microsc Res Tech , vol.74 , pp. 592-604
    • Hutter, E.1    Maysinger, D.2
  • 6
    • 84883775150 scopus 로고    scopus 로고
    • Gold-nanoparticle-based biosensors for detection of enzyme activity
    • Hutter E, Maysinger D. Gold-nanoparticle-based biosensors for detection of enzyme activity. Trends Pharmacol Sci. 2013; 34: 497-507.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 497-507
    • Hutter, E.1    Maysinger, D.2
  • 7
    • 84872311694 scopus 로고    scopus 로고
    • State of the art in gold nanoparticle synthesis
    • Zhao P, Li N, Astruc D. State of the art in gold nanoparticle synthesis. Coord Chem Rev. 2013; 257: 638-65.
    • (2013) Coord Chem Rev , vol.257 , pp. 638-665
    • Zhao, P.1    Li, N.2    Astruc, D.3
  • 8
    • 0035902370 scopus 로고    scopus 로고
    • Wet chemical synthesis of high aspect ratio cylindrical gold nanorods
    • Jana NR, Gearheart L, Murphy CJ. Wet chemical synthesis of high aspect ratio cylindrical gold nanorods. J Phys Chem B. 2001; 105: 4065-7.
    • (2001) J Phys Chem B , vol.105 , pp. 4065-4067
    • Jana, N.R.1    Gearheart, L.2    Murphy, C.J.3
  • 9
    • 0031997929 scopus 로고    scopus 로고
    • Hydroxylamine seeding of colloidal au nanoparticles in solution and on surfaces
    • Brown KR, Natan MJ. Hydroxylamine seeding of colloidal au nanoparticles in solution and on surfaces. Langmuir. 1998; 14: 726-8.
    • (1998) Langmuir , vol.14 , pp. 726-728
    • Brown, K.R.1    Natan, M.J.2
  • 10
    • 0038175155 scopus 로고    scopus 로고
    • Preparation and growth mechanism of gold nanorods (NRs) using seed-mediated growth method
    • Nikoobakht B, El-Sayed MA. Preparation and growth mechanism of gold nanorods (NRs) using seed-mediated growth method. Chem Mater. 2003; 15: 1957-62.
    • (2003) Chem Mater , vol.15 , pp. 1957-1962
    • Nikoobakht, B.1    El-Sayed, M.A.2
  • 11
    • 84875206491 scopus 로고    scopus 로고
    • Functionalizing nanoparticles with biological molecules: Developing chemistries that facilitate nanotechnology
    • Sapsford KE, Algar WR, Berti L, Gemmill KB, Casey BJ, Oh E, et al. Functionalizing nanoparticles with biological molecules: Developing chemistries that facilitate nanotechnology. Chem Rev. 2013; 113: 1904-2074.
    • (2013) Chem Rev , vol.113 , pp. 1904-2074
    • Sapsford, K.E.1    Algar, W.R.2    Berti, L.3    Gemmill, K.B.4    Casey, B.J.5    Oh, E.6
  • 12
    • 84902329592 scopus 로고    scopus 로고
    • Gold nanoparticles explore cells: Cellular uptake and their use as intracellular probes
    • Huefner A, Septiadi D, Wilts BD, Patel II, Kuan W-L, Fragniere A, et al. Gold nanoparticles explore cells: Cellular uptake and their use as intracellular probes. Methods. 2014; 68: 354-63.
    • (2014) Methods , vol.68 , pp. 354-363
    • Huefner, A.1    Septiadi, D.2    Wilts, B.D.3    Patel, I.I.4    Kuan, W.-L.5    Fragniere, A.6
  • 13
    • 84893043993 scopus 로고    scopus 로고
    • Uptake of engineered gold nanoparticles into mammalian cells
    • Dykman LA, Khlebtsov NG. Uptake of engineered gold nanoparticles into mammalian cells. Chem Rev. 2014; 114: 1258-88.
    • (2014) Chem Rev , vol.114 , pp. 1258-1288
    • Dykman, L.A.1    Khlebtsov, N.G.2
  • 14
    • 79954480999 scopus 로고    scopus 로고
    • Gold nanoparticles delivery in mammalian live cells: A critical review
    • Lévy R, Shaheen U, Cesbron Y, Sée V. Gold nanoparticles delivery in mammalian live cells: A critical review. Nano Reviews. 2010; 1: 10.3402/nano.v1i0.4889.
    • (2010) Nano Reviews , vol.1
    • Lévy, R.1    Shaheen, U.2    Cesbron, Y.3    Sée, V.4
  • 16
    • 84857250783 scopus 로고    scopus 로고
    • Gold nanoparticles as novel agents for cancer therapy
    • Jain S, Hirst DG, O'Sullivan JM. Gold nanoparticles as novel agents for cancer therapy. Br J Radiol. 2012; 85: 101-13.
    • (2012) Br J Radiol , vol.85 , pp. 101-113
    • Jain, S.1    Hirst, D.G.2    O'Sullivan, J.M.3
  • 17
  • 18
    • 84859252945 scopus 로고    scopus 로고
    • Size matters: Gold nanoparticles in targeted cancer drug delivery
    • Dreaden EC, Austin LA, Mackey MA, El-Sayed MA. Size matters: Gold nanoparticles in targeted cancer drug delivery. Ther Deliv. 2012; 3: 457-78.
    • (2012) Ther Deliv , vol.3 , pp. 457-478
    • Dreaden, E.C.1    Austin, L.A.2    Mackey, M.A.3    El-Sayed, M.A.4
  • 19
    • 79961172204 scopus 로고    scopus 로고
    • Intratumoral drug delivery with nanoparticulate carriers
    • Holback H, Yeo Y. Intratumoral drug delivery with nanoparticulate carriers. Pharm Res. 2011; 28: 1819-30.
    • (2011) Pharm Res , vol.28 , pp. 1819-1830
    • Holback, H.1    Yeo, Y.2
  • 20
    • 84884182689 scopus 로고    scopus 로고
    • Investigation of sub-100 nm gold nanoparticles for laser-induced thermotherapy of cancer
    • Leung J, Wu S, Chou K, Signorell R. Investigation of sub-100 nm gold nanoparticles for laser-induced thermotherapy of cancer. Nanomaterials. 2013; 3: 86-106.
    • (2013) Nanomaterials , vol.3 , pp. 86-106
    • Leung, J.1    Wu, S.2    Chou, K.3    Signorell, R.4
  • 21
    • 84924295890 scopus 로고    scopus 로고
    • [Internet] N.I.H: Clinical trials.
    • [Internet] NIH: Clinical trials. 2014. http://clinicaltrials.gov/
    • (2014)
  • 22
    • 78650348824 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine
    • Libutti SK, Paciotti GF, Byrnes AA, Alexander HR, Gannon WE, Walker M, et al. Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res. 2010; 16: 6139-49.
    • (2010) Clin Cancer Res , vol.16 , pp. 6139-6149
    • Libutti, S.K.1    Paciotti, G.F.2    Byrnes, A.A.3    Alexander, H.R.4    Gannon, W.E.5    Walker, M.6
  • 24
    • 84893643000 scopus 로고    scopus 로고
    • Cell-selective intracellular drug delivery using doxorubicin and a-helical peptides conjugated to gold nanoparticles
    • Park H, Tsutsumi H, Mihara H. Cell-selective intracellular drug delivery using doxorubicin and a-helical peptides conjugated to gold nanoparticles. Biomaterials. 2014; 35: 3480-7.
    • (2014) Biomaterials , vol.35 , pp. 3480-3487
    • Park, H.1    Tsutsumi, H.2    Mihara, H.3
  • 25
    • 84880445847 scopus 로고    scopus 로고
    • Organelle targeting: Third level of drug targeting
    • Sakhrani NM, Padh H. Organelle targeting: Third level of drug targeting. Drug Des Devel Ther. 2013; 7: 585-99.
    • (2013) Drug Des Devel Ther , vol.7 , pp. 585-599
    • Sakhrani, N.M.1    Padh, H.2
  • 26
    • 84863912661 scopus 로고    scopus 로고
    • Tat peptide-functionalized gold nanostars: Enhanced intracellular delivery and efficient nir photothermal therapy using ultralow irradiance
    • Yuan H, Fales AM, Vo-Dinh T. Tat peptide-functionalized gold nanostars: Enhanced intracellular delivery and efficient nir photothermal therapy using ultralow irradiance. J Am Chem Soc. 2012; 134: 11358-61.
    • (2012) J Am Chem Soc , vol.134 , pp. 11358-11361
    • Yuan, H.1    Fales, A.M.2    Vo-Dinh, T.3
  • 27
    • 52649181184 scopus 로고    scopus 로고
    • Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles
    • Kong T, Zeng J, Wang X, Yang X, Yang J, McQuarrie S, et al. Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles. Small. 2008; 4: 1537-43.
    • (2008) Small , vol.4 , pp. 1537-1543
    • Kong, T.1    Zeng, J.2    Wang, X.3    Yang, X.4    Yang, J.5    McQuarrie, S.6
  • 28
    • 77950814037 scopus 로고    scopus 로고
    • Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin
    • Brown SD, Nativo P, Smith J-A, Stirling D, Edwards PR, Venugopal B, et al. Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin. J Am Chem Soc. 2010; 132: 4678-84.
    • (2010) J Am Chem Soc , vol.132 , pp. 4678-4684
    • Brown, S.D.1    Nativo, P.2    Smith, J.-A.3    Stirling, D.4    Edwards, P.R.5    Venugopal, B.6
  • 29
    • 84884685174 scopus 로고    scopus 로고
    • Randomized phase II trial of weekly vs every 2 weeks vs. every 3 weeks nanoparticle albumin-bound paclitaxel with bevacizumab as first-line chemotherapy for metastatic breast cancer
    • e1
    • Seidman AD, Conlin AK, Bach A, Moynahan ME, Lake D, Forero A, et al. Randomized phase II trial of weekly vs. every 2 weeks vs. every 3 weeks nanoparticle albumin-bound paclitaxel with bevacizumab as first-line chemotherapy for metastatic breast cancer. Clin Breast Cancer. 2013; 13: 239-46.e1.
    • (2013) Clin Breast Cancer , vol.13 , pp. 239-246
    • Seidman, A.D.1    Conlin, A.K.2    Bach, A.3    Moynahan, M.E.4    Lake, D.5    Forero, A.6
  • 30
    • 84155167955 scopus 로고    scopus 로고
    • Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy
    • Jaggi AS, Singh N. Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy. Toxicology. 2012; 291: 1-9.
    • (2012) Toxicology , vol.291 , pp. 1-9
    • Jaggi, A.S.1    Singh, N.2
  • 31
    • 84902530810 scopus 로고    scopus 로고
    • Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis
    • Vyas D, Laput G, Vyas AK. Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis. Onco Targets Ther. 2014; 7: 1015-23.
    • (2014) Onco Targets Ther , vol.7 , pp. 1015-1023
    • Vyas, D.1    Laput, G.2    Vyas, A.K.3
  • 32
    • 84879337681 scopus 로고    scopus 로고
    • Inducing cancer cell death by targeting its nucleus: Solid gold nanospheres versus hollow gold nanocages
    • Mackey MA, Saira F, Mahmoud MA, El-Sayed MA. Inducing cancer cell death by targeting its nucleus: Solid gold nanospheres versus hollow gold nanocages. Bioconjug Chem. 2013; 24: 897-906.
    • (2013) Bioconjug Chem , vol.24 , pp. 897-906
    • Mackey, M.A.1    Saira, F.2    Mahmoud, M.A.3    El-Sayed, M.A.4
  • 33
    • 84880907153 scopus 로고    scopus 로고
    • A new anti- cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles
    • Chen W-H, Chen J-X, Cheng H, Chen C-S, Yang J, Xu X-D, et al. A new anti- cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles. Chem Commun (Camb). 2013; 49: 6403-5.
    • (2013) Chem Commun (Camb) , vol.49 , pp. 6403-6405
    • Chen, W.-H.1    Chen, J.-X.2    Cheng, H.3    Chen, C.-S.4    Yang, J.5    Xu, X.-D.6
  • 34
    • 80051516660 scopus 로고    scopus 로고
    • Doxorubicin- tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells
    • Wang F, Wang Y-C, Dou S, Xiong M-H, Sun T-M, Wang J. Doxorubicin- tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells. ACS Nano. 2011; 5: 3679-92.
    • (2011) ACS Nano , vol.5 , pp. 3679-3692
    • Wang, F.1    Wang, Y.-C.2    Dou, S.3    Xiong, M.-H.4    Sun, T.-M.5    Wang, J.6
  • 35
    • 35048826817 scopus 로고    scopus 로고
    • Paclitaxel-functionalized gold nanoparticles
    • Gibson JD, Khanal BP, Zubarev ER. Paclitaxel-functionalized gold nanoparticles. J Am Chem Soc. 2007; 129: 11653-61.
    • (2007) J Am Chem Soc , vol.129 , pp. 11653-11661
    • Gibson, J.D.1    Khanal, B.P.2    Zubarev, E.R.3
  • 36
    • 84901684201 scopus 로고    scopus 로고
    • Neuropilin-1-targeted gold nanoparticles enhance therapeutic efficacy of platinum(IV) drug for prostate cancer treatment
    • Kumar A, Huo S, Zhang X, Liu J, Tan A, Li S, et al. Neuropilin-1-targeted gold nanoparticles enhance therapeutic efficacy of platinum(IV) drug for prostate cancer treatment. ACS Nano. 2014; 8: 4205-20.
    • (2014) ACS Nano , vol.8 , pp. 4205-4220
    • Kumar, A.1    Huo, S.2    Zhang, X.3    Liu, J.4    Tan, A.5    Li, S.6
  • 37
    • 84883203589 scopus 로고    scopus 로고
    • Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy
    • Chen H, Zhang X, Dai S, Ma Y, Cui S, Achilefu S, et al. Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy. Theranostics. 2013; 3: 633-49.
    • (2013) Theranostics , vol.3 , pp. 633-649
    • Chen, H.1    Zhang, X.2    Dai, S.3    Ma, Y.4    Cui, S.5    Achilefu, S.6
  • 42
    • 84869768331 scopus 로고    scopus 로고
    • Detecting and destroying cancer cells in more than one way with noble metals and different confinement properties on the nanoscale
    • Dreaden EC, El-Sayed MA. Detecting and destroying cancer cells in more than one way with noble metals and different confinement properties on the nanoscale. Acc Chem Res. 2012; 45: 1854-65.
    • (2012) Acc Chem Res , vol.45 , pp. 1854-1865
    • Dreaden, E.C.1    El-Sayed, M.A.2
  • 43
    • 73949087550 scopus 로고    scopus 로고
    • Effect of surface properties on nanoparticle-cell interactions
    • Verma A, Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small. 2010; 6: 12-21.
    • (2010) Small , vol.6 , pp. 12-21
    • Verma, A.1    Stellacci, F.2
  • 44
    • 82455211825 scopus 로고    scopus 로고
    • Applications of vectorized gold nanoparticles to the diagnosis and therapy of cancer
    • Llevot A, Astruc D. Applications of vectorized gold nanoparticles to the diagnosis and therapy of cancer. Chem Soc Rev. 2012; 41: 242-57.
    • (2012) Chem Soc Rev , vol.41 , pp. 242-257
    • Llevot, A.1    Astruc, D.2
  • 45
    • 65249086959 scopus 로고    scopus 로고
    • Understanding the role of surface charges in cellular adsorption versus internalization by selectively removing gold nanoparticles on the cell surface with a I2/KI etchant
    • Cho EC, Xie J, Wurm PA, Xia Y. Understanding the role of surface charges in cellular adsorption versus internalization by selectively removing gold nanoparticles on the cell surface with a I2/KI etchant. Nano Lett. 2009; 9: 1080-4.
    • (2009) Nano Lett , vol.9 , pp. 1080-1084
    • Cho, E.C.1    Xie, J.2    Wurm, P.A.3    Xia, Y.4
  • 46
    • 84922061271 scopus 로고    scopus 로고
    • Gold nanoparticles induce nuclear damage in breast cancer cells which is further amplified by hyperthermia
    • Kodiha M, Hutter E, Boridy S, Juhas M, Maysinger D, Stochaj U. Gold nanoparticles induce nuclear damage in breast cancer cells which is further amplified by hyperthermia. Cell Mol Life Sci. 2014; 71: 4259-73.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 4259-4273
    • Kodiha, M.1    Hutter, E.2    Boridy, S.3    Juhas, M.4    Maysinger, D.5    Stochaj, U.6
  • 47
    • 79851500107 scopus 로고    scopus 로고
    • Selective targeting of gold nanorods at the mitochondria of cancer cells: Implications for cancer therapy
    • Wang L, Liu Y, Li W, Jiang X, Ji Y, Wu X, et al. Selective targeting of gold nanorods at the mitochondria of cancer cells: Implications for cancer therapy. Nano Lett. 2010; 11: 772-80.
    • (2010) Nano Lett , vol.11 , pp. 772-780
    • Wang, L.1    Liu, Y.2    Li, W.3    Jiang, X.4    Ji, Y.5    Wu, X.6
  • 48
    • 2442660623 scopus 로고    scopus 로고
    • Cellular trajectories of peptide-modified gold particle complexes: Comparison of nuclear localization signals and peptide transduction domains
    • Tkachenko AG, Xie H, Liu YL, Coleman D, Ryan J, Glomm WR, et al. Cellular trajectories of peptide-modified gold particle complexes: Comparison of nuclear localization signals and peptide transduction domains. Bioconjug Chem. 2004; 15: 482-90.
    • (2004) Bioconjug Chem , vol.15 , pp. 482-490
    • Tkachenko, A.G.1    Xie, H.2    Liu, Y.L.3    Coleman, D.4    Ryan, J.5    Glomm, W.R.6
  • 49
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • Chithrani BD, Ghazani AA, Chan WCW. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 2006; 6: 662-8.
    • (2006) Nano Lett , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 50
    • 34547302844 scopus 로고    scopus 로고
    • Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes
    • Chithrani BD, Chan WCW. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett. 2007; 7: 1542-50.
    • (2007) Nano Lett , vol.7 , pp. 1542-1550
    • Chithrani, B.D.1    Chan, W.C.W.2
  • 51
    • 58549089280 scopus 로고    scopus 로고
    • Cellular uptake of gold nanoparticles directly cross-linked with carrier peptides by osteosarcoma cells
    • Mandal D, Maran A, Yaszemski M, Bolander M, Sarkar G. Cellular uptake of gold nanoparticles directly cross-linked with carrier peptides by osteosarcoma cells. J Mater Sci Mater Med. 2009; 20: 347-50.
    • (2009) J Mater Sci Mater Med , vol.20 , pp. 347-350
    • Mandal, D.1    Maran, A.2    Yaszemski, M.3    Bolander, M.4    Sarkar, G.5
  • 52
    • 52649159760 scopus 로고    scopus 로고
    • Functional gold nanoparticle-peptide complexes as cell-targeting agents
    • Sun L, Liu D, Wang Z. Functional gold nanoparticle-peptide complexes as cell-targeting agents. Langmuir. 2008; 24: 10293-7.
    • (2008) Langmuir , vol.24 , pp. 10293-10297
    • Sun, L.1    Liu, D.2    Wang, Z.3
  • 53
    • 84864001167 scopus 로고    scopus 로고
    • Peptide-mediated cell penetration and targeted delivery of gold nanoparticles into lysosomes
    • Dekiwadia CD, Lawrie AC, Fecondo JV. Peptide-mediated cell penetration and targeted delivery of gold nanoparticles into lysosomes. J Pept Sci. 2012; 18: 527-34.
    • (2012) J Pept Sci , vol.18 , pp. 527-534
    • Dekiwadia, C.D.1    Lawrie, A.C.2    Fecondo, J.V.3
  • 54
    • 84865141619 scopus 로고    scopus 로고
    • Self-assembled plasmonic vesicles of sers-encoded amphiphilic gold nanoparticles for cancer cell targeting and traceable intracellular drug delivery
    • Song J, Zhou J, Duan H. Self-assembled plasmonic vesicles of sers-encoded amphiphilic gold nanoparticles for cancer cell targeting and traceable intracellular drug delivery. J Am Chem Soc. 2012; 134: 13458-69.
    • (2012) J Am Chem Soc , vol.134 , pp. 13458-13469
    • Song, J.1    Zhou, J.2    Duan, H.3
  • 56
    • 76149117212 scopus 로고    scopus 로고
    • Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosis
    • Kang B, Mackey MA, El-Sayed MA. Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosis. J Am Chem Soc. 2010; 132: 1517-9.
    • (2010) J Am Chem Soc , vol.132 , pp. 1517-1519
    • Kang, B.1    Mackey, M.A.2    El-Sayed, M.A.3
  • 57
    • 79952976353 scopus 로고    scopus 로고
    • Cellular uptake and nanoscale localization of gold nanoparticles in cancer using label-free confocal raman microscopy
    • Shah NB, Dong J, Bischof JC. Cellular uptake and nanoscale localization of gold nanoparticles in cancer using label-free confocal raman microscopy. Mol Pharm. 2010; 8: 176-84.
    • (2010) Mol Pharm , vol.8 , pp. 176-184
    • Shah, N.B.1    Dong, J.2    Bischof, J.C.3
  • 59
    • 36849070899 scopus 로고    scopus 로고
    • Cellular uptake of gold nanoparticles passivated with bsa-sv40 large t antigen conjugates
    • Ryan JA, Overton KW, Speight ME, Oldenburg CM, Loo L, Robarge W, et al. Cellular uptake of gold nanoparticles passivated with bsa-sv40 large t antigen conjugates. Anal Chem. 2007; 79: 9150-9.
    • (2007) Anal Chem , vol.79 , pp. 9150-9159
    • Ryan, J.A.1    Overton, K.W.2    Speight, M.E.3    Oldenburg, C.M.4    Loo, L.5    Robarge, W.6
  • 60
    • 84903438002 scopus 로고    scopus 로고
    • Ultrasmall gold nanoparticles as carriers for nucleus-based gene therapy due to size-dependent nuclear entry
    • Huo S, Jin S, Ma X, Xue X, Yang K, Kumar A, et al. Ultrasmall gold nanoparticles as carriers for nucleus-based gene therapy due to size-dependent nuclear entry. ACS Nano. 2014; 8: 5852-62.
    • (2014) ACS Nano , vol.8 , pp. 5852-5862
    • Huo, S.1    Jin, S.2    Ma, X.3    Xue, X.4    Yang, K.5    Kumar, A.6
  • 61
    • 25444484386 scopus 로고    scopus 로고
    • Tat peptide as an efficient molecule to translocate gold nanoparticles into the cell nucleus
    • de la Fuente JM, Berry CC. Tat peptide as an efficient molecule to translocate gold nanoparticles into the cell nucleus. Bioconjug Chem. 2005; 16: 1176-80.
    • (2005) Bioconjug Chem , vol.16 , pp. 1176-1180
    • de la Fuente, J.M.1    Berry, C.C.2
  • 64
    • 84866672211 scopus 로고    scopus 로고
    • Facile preparation of cationic gold nanoparticle-bioconjugates for cell penetration and nuclear targeting
    • Ojea-Jimenez I, Garcia-Fernandez L, Lorenzo J, Puntes VF. Facile preparation of cationic gold nanoparticle-bioconjugates for cell penetration and nuclear targeting. ACS Nano. 2012; 6: 7692-702.
    • (2012) ACS Nano , vol.6 , pp. 7692-7702
    • Ojea-Jimenez, I.1    Garcia-Fernandez, L.2    Lorenzo, J.3    Puntes, V.F.4
  • 66
    • 51849119730 scopus 로고    scopus 로고
    • Uptake and intracellular fate of surface-modified gold nanoparticles
    • Nativo P, Prior IA, Brust M. Uptake and intracellular fate of surface-modified gold nanoparticles. ACS Nano. 2008; 2: 1639-44.
    • (2008) ACS Nano , vol.2 , pp. 1639-1644
    • Nativo, P.1    Prior, I.A.2    Brust, M.3
  • 68
    • 84907494139 scopus 로고    scopus 로고
    • Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention
    • Yang C, Uertz J, Yohan D, Chithrani BD. Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention. Nanoscale. 2014; 6: 12026-33.
    • (2014) Nanoscale , vol.6 , pp. 12026-12033
    • Yang, C.1    Uertz, J.2    Yohan, D.3    Chithrani, B.D.4
  • 69
    • 25444448098 scopus 로고    scopus 로고
    • Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity
    • Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small. 2005; 1: 325-7.
    • (2005) Small , vol.1 , pp. 325-327
    • Connor, E.E.1    Mwamuka, J.2    Gole, A.3    Murphy, C.J.4    Wyatt, M.D.5
  • 70
    • 33646920343 scopus 로고    scopus 로고
    • Synthesis and grafting of thioctic acid-PEG-folate conjugates onto au nanoparticles for selective targeting of folate receptor-positive tumor cells
    • Dixit V, Van den Bossche J, Sherman DM, Thompson DH, Andres RP. Synthesis and grafting of thioctic acid-PEG-folate conjugates onto au nanoparticles for selective targeting of folate receptor-positive tumor cells. Bioconjug Chem. 2006; 17: 603-9.
    • (2006) Bioconjug Chem , vol.17 , pp. 603-609
    • Dixit, V.1    Van den Bossche, J.2    Sherman, D.M.3    Thompson, D.H.4    Andres, R.P.5
  • 73
    • 34548240631 scopus 로고    scopus 로고
    • Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells
    • Bhattacharya R, Patra CR, Earl A, Wang S, Katarya A, Lu L, et al. Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells. Nanomed Nanotechnol Biol Med. 2007; 3: 224-38.
    • (2007) Nanomed Nanotechnol Biol Med , vol.3 , pp. 224-238
    • Bhattacharya, R.1    Patra, C.R.2    Earl, A.3    Wang, S.4    Katarya, A.5    Lu, L.6
  • 74
    • 84881365378 scopus 로고    scopus 로고
    • Surface decorated gold nanoparticles by linear and cyclic peptides as molecular transporters
    • Shirazi AN, Tiwari RK, Oh D, Sullivan B, McCaffrey K, Mandal D, et al. Surface decorated gold nanoparticles by linear and cyclic peptides as molecular transporters. Mol Pharm. 2013; 10: 10.1021/mp400199e.
    • (2013) Mol Pharm , vol.10
    • Shirazi, A.N.1    Tiwari, R.K.2    Oh, D.3    Sullivan, B.4    McCaffrey, K.5    Mandal, D.6
  • 75
    • 28044446787 scopus 로고    scopus 로고
    • Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: A microscopic overview
    • Shukla R, Bansal V, Chaudhary M, Basu A, Bhonde RR, Sastry M. Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: A microscopic overview. Langmuir. 2005; 21: 10644-54.
    • (2005) Langmuir , vol.21 , pp. 10644-10654
    • Shukla, R.1    Bansal, V.2    Chaudhary, M.3    Basu, A.4    Bhonde, R.R.5    Sastry, M.6
  • 76
    • 84906807354 scopus 로고    scopus 로고
    • Sandwich-type Au-PEI/DNA/PEI-Dexa nanocomplex for nucleus-targeted gene delivery in vitro and in vivo
    • Chen Z, Zhang L, He Y, Li Y. Sandwich-type Au-PEI/DNA/PEI-Dexa nanocomplex for nucleus-targeted gene delivery in vitro and in vivo. ACS Appl Mater Interfaces. 2014; 6: 14196-206.
    • (2014) ACS Appl Mater Interfaces , vol.6 , pp. 14196-14206
    • Chen, Z.1    Zhang, L.2    He, Y.3    Li, Y.4
  • 77
    • 33746191917 scopus 로고    scopus 로고
    • Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles
    • Han G, You C-C, Kim B-j, Turingan RS, Forbes NS, Martin CT, et al. Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles. Angew Chem Int Ed Engl. 2006; 45: 3165-9.
    • (2006) Angew Chem Int Ed Engl , vol.45 , pp. 3165-3169
    • Han, G.1    You, C.-C.2    Kim, B.-J.3    Turingan, R.S.4    Forbes, N.S.5    Martin, C.T.6
  • 78
    • 19944401541 scopus 로고    scopus 로고
    • Surface plasmon resonance scattering and absorption of anti-egfr antibody conjugated gold nanoparticles in cancer diagnostics: Applications in oral cancer
    • El-Sayed IH, Huang X, El-Sayed MA. Surface plasmon resonance scattering and absorption of anti-egfr antibody conjugated gold nanoparticles in cancer diagnostics: Applications in oral cancer. Nano Lett. 2005; 5: 829-34.
    • (2005) Nano Lett , vol.5 , pp. 829-834
    • El-Sayed, I.H.1    Huang, X.2    El-Sayed, M.A.3
  • 79
    • 33244457595 scopus 로고    scopus 로고
    • Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods
    • Huang X, El-Sayed IH, Qian W, El-Sayed MA. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J Am Chem Soc. 2006; 128: 2115-20.
    • (2006) J Am Chem Soc , vol.128 , pp. 2115-2120
    • Huang, X.1    El-Sayed, I.H.2    Qian, W.3    El-Sayed, M.A.4
  • 80
    • 38849085772 scopus 로고    scopus 로고
    • Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells
    • Hauck TS, Ghazani AA, Chan WCW. Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small. 2008; 4: 153-9.
    • (2008) Small , vol.4 , pp. 153-159
    • Hauck, T.S.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 81
    • 80052045191 scopus 로고    scopus 로고
    • Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size
    • Oh E, Delehanty JB, Sapsford KE, Susumu K, Goswami R, Blanco-Canosa JB, et al. Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size. ACS Nano. 2011; 5: 6434-48.
    • (2011) ACS Nano , vol.5 , pp. 6434-6448
    • Oh, E.1    Delehanty, J.B.2    Sapsford, K.E.3    Susumu, K.4    Goswami, R.5    Blanco-Canosa, J.B.6
  • 82
    • 84880577646 scopus 로고    scopus 로고
    • Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells
    • Liu X, Huang N, Li H, Jin Q, Ji J. Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. Langmuir. 2013; 29: 9138-48.
    • (2013) Langmuir , vol.29 , pp. 9138-9148
    • Liu, X.1    Huang, N.2    Li, H.3    Jin, Q.4    Ji, J.5
  • 83
    • 84873260520 scopus 로고    scopus 로고
    • Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
    • Coradeghini R, Gioria S, García CP, Nativo P, Franchini F, Gilliland D, et al. Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts. Toxicol Lett. 2013; 217: 205-16.
    • (2013) Toxicol Lett , vol.217 , pp. 205-216
    • Coradeghini, R.1    Gioria, S.2    García, C.P.3    Nativo, P.4    Franchini, F.5    Gilliland, D.6
  • 85
    • 84864670257 scopus 로고    scopus 로고
    • Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo
    • Huang K, Ma H, Liu J, Huo S, Kumar A, Wei T, et al. Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo. ACS Nano. 2012; 6: 4483-93.
    • (2012) ACS Nano , vol.6 , pp. 4483-4493
    • Huang, K.1    Ma, H.2    Liu, J.3    Huo, S.4    Kumar, A.5    Wei, T.6
  • 86
  • 87
    • 38349036163 scopus 로고    scopus 로고
    • Mito-porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion
    • Yamada Y, Akita H, Kamiya H, Kogure K, Yamamoto T, Shinohara Y, et al. Mito-porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion. Biochim Biophys Acta. 2008; 1778: 423-32.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 423-432
    • Yamada, Y.1    Akita, H.2    Kamiya, H.3    Kogure, K.4    Yamamoto, T.5    Shinohara, Y.6
  • 88
    • 84883192484 scopus 로고    scopus 로고
    • Surface chemistry of gold nanorods: Origin of cell membrane damage and cytotoxicity
    • Wang L, Jiang X, Ji Y, Bai R, Zhao Y, Wu X, et al. Surface chemistry of gold nanorods: Origin of cell membrane damage and cytotoxicity. Nanoscale. 2013; 5: 8384-91.
    • (2013) Nanoscale , vol.5 , pp. 8384-8391
    • Wang, L.1    Jiang, X.2    Ji, Y.3    Bai, R.4    Zhao, Y.5    Wu, X.6
  • 89
    • 84890852662 scopus 로고    scopus 로고
    • Targeted surface- functionalized gold nanoclusters for mitochondrial imaging
    • Zhuang Q, Jia H, Du L, Li Y, Chen Z, Huang S, et al. Targeted surface- functionalized gold nanoclusters for mitochondrial imaging. Biosensors Bioelectron. 2014; 55: 76-82.
    • (2014) Biosensors Bioelectron , vol.55 , pp. 76-82
    • Zhuang, Q.1    Jia, H.2    Du, L.3    Li, Y.4    Chen, Z.5    Huang, S.6
  • 90
    • 84887946947 scopus 로고    scopus 로고
    • Surface plasmon resonance-induced photoactivation of gold nanoparticles as mitochondria- targeted therapeutic agents for pancreatic cancer
    • Mocan L, Ilie I, Tabaran FA, Dana B, Zaharie F, Zdrehus C, et al. Surface plasmon resonance-induced photoactivation of gold nanoparticles as mitochondria- targeted therapeutic agents for pancreatic cancer. Expert Opin Ther Targets. 2013; 17: 1383-93.
    • (2013) Expert Opin Ther Targets , vol.17 , pp. 1383-1393
    • Mocan, L.1    Ilie, I.2    Tabaran, F.A.3    Dana, B.4    Zaharie, F.5    Zdrehus, C.6
  • 91
    • 84923207020 scopus 로고    scopus 로고
    • The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate
    • Marrache S, Dhar S. The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate. Chem Science. 2015. doi:10.1039/C4SC01963.
    • (2015) Chem Science
    • Marrache, S.1    Dhar, S.2
  • 92
    • 80051776218 scopus 로고    scopus 로고
    • Addressing brain tumors with targeted gold nanoparticles: A new gold standard for hydrophobic drug delivery?
    • Cheng Y, Meyers JD, Agnes RS, Doane TL, Kenney ME, Broome A-M, et al. Addressing brain tumors with targeted gold nanoparticles: A new gold standard for hydrophobic drug delivery? Small. 2011; 7: 2301-6.
    • (2011) Small. , vol.7 , pp. 2301-2306
    • Cheng, Y.1    Meyers, J.D.2    Agnes, R.S.3    Doane, T.L.4    Kenney, M.E.5    Broome, A.-M.6
  • 93
    • 84858713151 scopus 로고    scopus 로고
    • Gold nanoparticles capped by a gc-containing peptide functionalized with an rgd motif for integrin targeting
    • Scarì G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, et al. Gold nanoparticles capped by a gc-containing peptide functionalized with an rgd motif for integrin targeting. Bioconjug Chem. 2012; 23: 340-9.
    • (2012) Bioconjug Chem , vol.23 , pp. 340-349
    • Scarì, G.1    Porta, F.2    Fascio, U.3    Avvakumova, S.4    Dal Santo, V.5    De Simone, M.6
  • 95
    • 84903475162 scopus 로고    scopus 로고
    • Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency
    • Sykes EA, Chen J, Zheng G, Chan WCW. Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency. ACS Nano. 2014; 8: 5696-706.
    • (2014) ACS Nano , vol.8 , pp. 5696-5706
    • Sykes, E.A.1    Chen, J.2    Zheng, G.3    Chan, W.C.W.4
  • 96
    • 61649110773 scopus 로고    scopus 로고
    • Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells
    • Eghtedari M, Liopo AV, Copland JA, Oraevsky AA, Motamedi M. Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells. Nano Lett. 2008; 9: 287-91.
    • (2008) Nano Lett , vol.9 , pp. 287-291
    • Eghtedari, M.1    Liopo, A.V.2    Copland, J.A.3    Oraevsky, A.A.4    Motamedi, M.5
  • 97
    • 33646257222 scopus 로고    scopus 로고
    • Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles
    • El-Sayed IH, Huang X, El-Sayed MA. Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles. Cancer Lett. 2006; 239: 129-35.
    • (2006) Cancer Lett , vol.239 , pp. 129-135
    • El-Sayed, I.H.1    Huang, X.2    El-Sayed, M.A.3
  • 98
    • 84875604713 scopus 로고    scopus 로고
    • Cancer biology and the nuclear envelope: A convoluted relationship
    • de las Heras JI, Batrakou DG, Schirmer EC. Cancer biology and the nuclear envelope: A convoluted relationship. Semin Cancer Biol. 2013; 23: 125-37.
    • (2013) Semin Cancer Biol , vol.23 , pp. 125-137
    • de las Heras, J.I.1    Batrakou, D.G.2    Schirmer, E.C.3
  • 101
    • 84873522918 scopus 로고    scopus 로고
    • Nuclear importin alpha and its physiological importance
    • Miyamoto Y, Loveland KL, Yoneda Y. Nuclear importin alpha and its physiological importance. Commun Integr Biol. 2012; 5: 220-2.
    • (2012) Commun Integr Biol , vol.5 , pp. 220-222
    • Miyamoto, Y.1    Loveland, K.L.2    Yoneda, Y.3
  • 103
    • 84866376082 scopus 로고    scopus 로고
    • Revisiting the nucleolus: From marker to dynamic integrator of cancer signaling
    • Ruggero D. Revisiting the nucleolus: From marker to dynamic integrator of cancer signaling. Sci Signal. 2012; 5: pe38.
    • (2012) Sci Signal , vol.5 , pp. pe38
    • Ruggero, D.1
  • 105
    • 84857739015 scopus 로고    scopus 로고
    • Global enhancement of nuclear localization-dependent nuclear transport in transformed cells
    • Kuusisto HV, Wagstaff KM, Alvisi G, Roth DM, Jans DA. Global enhancement of nuclear localization-dependent nuclear transport in transformed cells. FASEB J. 2012; 26: 1181-93.
    • (2012) FASEB J , vol.26 , pp. 1181-1193
    • Kuusisto, H.V.1    Wagstaff, K.M.2    Alvisi, G.3    Roth, D.M.4    Jans, D.A.5
  • 106
    • 0025371353 scopus 로고
    • The permeability of the nuclear envelope in dividing and nondividing cell cultures
    • Feldherr CM, Akin D. The permeability of the nuclear envelope in dividing and nondividing cell cultures. J Cell Biol. 1990; 111: 1-8.
    • (1990) J Cell Biol , vol.111 , pp. 1-8
    • Feldherr, C.M.1    Akin, D.2
  • 107
    • 0026353709 scopus 로고
    • Signal-mediated nuclear transport in proliferating and growth-arrested BALB/c 3T3 cells
    • Feldherr CM, Akin D. Signal-mediated nuclear transport in proliferating and growth-arrested BALB/c 3T3 cells. J Cell Biol. 1991; 115: 933-9.
    • (1991) J Cell Biol , vol.115 , pp. 933-939
    • Feldherr, C.M.1    Akin, D.2
  • 108
    • 0027197282 scopus 로고
    • Regulation of nuclear transport in proliferating and quiescent cells
    • Feldherr CM, Akin D. Regulation of nuclear transport in proliferating and quiescent cells. Exp Cell Res. 1993; 205: 179-86.
    • (1993) Exp Cell Res , vol.205 , pp. 179-186
    • Feldherr, C.M.1    Akin, D.2
  • 109
  • 110
    • 0036175701 scopus 로고    scopus 로고
    • Nuclear pore complex is able to transport macromolecules with diameters of ~39 nm
    • Panté N, Kann M. Nuclear pore complex is able to transport macromolecules with diameters of ~39 nm. Mol Biol Cell. 2002; 13: 425-34.
    • (2002) Mol Biol Cell , vol.13 , pp. 425-434
    • Panté, N.1    Kann, M.2
  • 111
    • 0035691870 scopus 로고    scopus 로고
    • Regulation of functional nuclear pore size in fibroblasts
    • Feldherr CM, Akin D, Cohen RJ. Regulation of functional nuclear pore size in fibroblasts. J Cell Sci. 2001; 114: 4621-7.
    • (2001) J Cell Sci , vol.114 , pp. 4621-4627
    • Feldherr, C.M.1    Akin, D.2    Cohen, R.J.3
  • 112
    • 0031454975 scopus 로고    scopus 로고
    • The location of the transport gate in the nuclear pore complex
    • Feldherr CM, Akin D. The location of the transport gate in the nuclear pore complex. J Cell Sci. 1997; 110: 3065-70.
    • (1997) J Cell Sci , vol.110 , pp. 3065-3070
    • Feldherr, C.M.1    Akin, D.2
  • 113
    • 0035583381 scopus 로고    scopus 로고
    • Purification of molecularly bridged metal nanoparticle arrays by centrifugation and size exclusion chromatography
    • Novak JP, Nickerson C, Franzen S, Feldheim DL. Purification of molecularly bridged metal nanoparticle arrays by centrifugation and size exclusion chromatography. Anal Chem. 2001; 73: 5758-61.
    • (2001) Anal Chem , vol.73 , pp. 5758-5761
    • Novak, J.P.1    Nickerson, C.2    Franzen, S.3    Feldheim, D.L.4
  • 114
    • 79959809016 scopus 로고    scopus 로고
    • Negotiation of intracellular membrane barriers by TAT-modified gold nanoparticles
    • Krpetic Ž, Saleemi S, Prior IA, Sée V, Qureshi R, Brust M. Negotiation of intracellular membrane barriers by TAT-modified gold nanoparticles. ACS Nano. 2011; 5: 5195-201.
    • (2011) ACS Nano , vol.5 , pp. 5195-5201
    • Krpetic, Ž.1    Saleemi, S.2    Prior, I.A.3    Sée, V.4    Qureshi, R.5    Brust, M.6
  • 115
    • 84870324924 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport blockage by SV40 peptide-modified gold nanoparticles induces cellular autophagy
    • Tsai TL, Hou CC, Wang HC, Yang ZS, Yeh CS, Shieh DB, et al. Nucleocytoplasmic transport blockage by SV40 peptide-modified gold nanoparticles induces cellular autophagy. Int J Nanomedicine. 2012; 7: 5215-34.
    • (2012) Int J Nanomedicine , vol.7 , pp. 5215-5234
    • Tsai, T.L.1    Hou, C.C.2    Wang, H.C.3    Yang, Z.S.4    Yeh, C.S.5    Shieh, D.B.6
  • 116
    • 84866676318 scopus 로고    scopus 로고
    • Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA
    • Huschka R, Barhoumi A, Liu Q, Roth JA, Ji L, Halas NJ. Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA. ACS Nano. 2012; 6: 7681-91.
    • (2012) ACS Nano , vol.6 , pp. 7681-7691
    • Huschka, R.1    Barhoumi, A.2    Liu, Q.3    Roth, J.A.4    Ji, L.5    Halas, N.J.6
  • 117
    • 80054014120 scopus 로고    scopus 로고
    • Inhibition of xenograft tumor growth in mice by gold nanoparticle-assisted delivery of short hairpin RNAs against Mcl-1L
    • Ryou S-M, Park M, Kim J-M, Jeon CO, Yun C-H, Han SH, et al. Inhibition of xenograft tumor growth in mice by gold nanoparticle-assisted delivery of short hairpin RNAs against Mcl-1L. J Biotechnol. 2011; 156: 89-94.
    • (2011) J Biotechnol , vol.156 , pp. 89-94
    • Ryou, S.-M.1    Park, M.2    Kim, J.-M.3    Jeon, C.O.4    Yun, C.-H.5    Han, S.H.6
  • 118
    • 77953202973 scopus 로고    scopus 로고
    • A functionalized gold nanoparticles-assisted universal carrier for antisense DNA
    • Kim J-H, Jang HH, Ryou S-M, Kim S, Bae J, Lee K, et al. A functionalized gold nanoparticles-assisted universal carrier for antisense DNA. Chem Commun (Camb). 2010; 46: 4151-3.
    • (2010) Chem Commun (Camb) , vol.46 , pp. 4151-4153
    • Kim, J.-H.1    Jang, H.H.2    Ryou, S.-M.3    Kim, S.4    Bae, J.5    Lee, K.6
  • 119
    • 79251597782 scopus 로고    scopus 로고
    • Modulation of biological processes in the nucleus by delivery of DNA oligonucleotides conjugated with gold nanoparticles
    • Kim D-W, Kim J-H, Park M, Yeom J-H, Go H, Kim S, et al. Modulation of biological processes in the nucleus by delivery of DNA oligonucleotides conjugated with gold nanoparticles. Biomaterials. 2011; 32: 2593-604.
    • (2011) Biomaterials , vol.32 , pp. 2593-2604
    • Kim, D.-W.1    Kim, J.-H.2    Park, M.3    Yeom, J.-H.4    Go, H.5    Kim, S.6
  • 120
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine. Annu Rev Genet. 2005; 39: 359-407.
    • (2005) Annu Rev Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 121
    • 71549171732 scopus 로고    scopus 로고
    • Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism
    • Pathania D, Millard M, Neamati N. Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism. Adv Drug Del Rev. 2009; 61: 1250-75.
    • (2009) Adv Drug Del Rev , vol.61 , pp. 1250-1275
    • Pathania, D.1    Millard, M.2    Neamati, N.3
  • 122
    • 84871604292 scopus 로고    scopus 로고
    • Targeting cancer cell mitochondria as a therapeutic approach
    • Wen S, Zhu D, Huang P. Targeting cancer cell mitochondria as a therapeutic approach. Future Med Chem. 2012; 5: 53-67.
    • (2012) Future Med Chem , vol.5 , pp. 53-67
    • Wen, S.1    Zhu, D.2    Huang, P.3
  • 123
    • 0242669353 scopus 로고    scopus 로고
    • Protein insertion into the mitochondrial inner membrane by a twin-pore translocase
    • Rehling P, Model K, Brandner K, Kovermann P, Sickmann A, Meyer HE, et al. Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science. 2003; 299: 1747-51.
    • (2003) Science , vol.299 , pp. 1747-1751
    • Rehling, P.1    Model, K.2    Brandner, K.3    Kovermann, P.4    Sickmann, A.5    Meyer, H.E.6
  • 124
    • 84900395214 scopus 로고    scopus 로고
    • Mitochondrial channels: Ion fluxes and more
    • Szabo I, Zoratti M. Mitochondrial channels: Ion fluxes and more. Physiol Rev. 2014; 94: 519-608.
    • (2014) Physiol Rev , vol.94 , pp. 519-608
    • Szabo, I.1    Zoratti, M.2
  • 125
    • 80155167926 scopus 로고    scopus 로고
    • Mitochondria-targeted small molecule therapeutics and probes
    • Smith RA, Hartley RC, Murphy MP. Mitochondria-targeted small molecule therapeutics and probes. Antioxid Redox Signal. 2011; 15: 3021-38.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 3021-3038
    • Smith, R.A.1    Hartley, R.C.2    Murphy, M.P.3
  • 127
    • 44449122444 scopus 로고    scopus 로고
    • Increased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose clinical electron beams on tumor-bearing mice
    • Chang M-Y, Shiau A-L, Chen Y-H, Chang C-J, Chen HHW, Wu C-L. Increased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose clinical electron beams on tumor-bearing mice. Cancer Sci. 2008; 99: 1479-84.
    • (2008) Cancer Sci , vol.99 , pp. 1479-1484
    • Chang, M.-Y.1    Shiau, A.-L.2    Chen, Y.-H.3    Chang, C.-J.4    Chen, H.H.W.5    Wu, C.-L.6
  • 128
    • 34547444104 scopus 로고    scopus 로고
    • Molecular effects of uptake of gold nanoparticles in HeLa cells
    • Khan JA, Pillai B, Das TK, Singh Y, Maiti S. Molecular effects of uptake of gold nanoparticles in HeLa cells. ChemBioChem. 2007; 8: 1237-40.
    • (2007) ChemBioChem , vol.8 , pp. 1237-1240
    • Khan, J.A.1    Pillai, B.2    Das, T.K.3    Singh, Y.4    Maiti, S.5
  • 129
    • 62249098384 scopus 로고    scopus 로고
    • Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles
    • Cho W-S, Cho M, Jeong J, Choi M, Cho H-Y, Han BS, et al. Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles. Toxicol Appl Pharmacol. 2009; 236: 16-24.
    • (2009) Toxicol Appl Pharmacol , vol.236 , pp. 16-24
    • Cho, W.-S.1    Cho, M.2    Jeong, J.3    Choi, M.4    Cho, H.-Y.5    Han, B.S.6
  • 130
    • 84555194632 scopus 로고    scopus 로고
    • Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis
    • Tsai Y-Y, Huang Y-H, Chao Y-L, Hu K-Y, Chin L-T, Chou S-H, et al. Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis. ACS Nano. 2011; 5: 9354-69.
    • (2011) ACS Nano , vol.5 , pp. 9354-9369
    • Tsai, Y.-Y.1    Huang, Y.-H.2    Chao, Y.-L.3    Hu, K.-Y.4    Chin, L.-T.5    Chou, S.-H.6
  • 132
    • 84903463411 scopus 로고    scopus 로고
    • Surface chemistry of gold nanoparticles mediates their exocytosis in macrophages
    • Oh N, Park J-H. Surface chemistry of gold nanoparticles mediates their exocytosis in macrophages. ACS Nano. 2014; 8: 6232-41.
    • (2014) ACS Nano. , vol.8 , pp. 6232-6241
    • Oh, N.1    Park, J.-H.2
  • 133
    • 84873720901 scopus 로고    scopus 로고
    • In vivo toxicity, biodistribution, and clearance of glutathione-coated gold nanoparticles
    • Simpson CA, Salleng KJ, Cliffel DE, Feldheim DL. In vivo toxicity, biodistribution, and clearance of glutathione-coated gold nanoparticles. Nanomedicine. 2013; 9: 257-63.
    • (2013) Nanomedicine , vol.9 , pp. 257-263
    • Simpson, C.A.1    Salleng, K.J.2    Cliffel, D.E.3    Feldheim, D.L.4
  • 135
    • 84875536799 scopus 로고    scopus 로고
    • The nuclear import receptor kpnb1 and its potential as an anticancer therapeutic target
    • van der Watt PJ, Stowell CL, Leaner VD. The nuclear import receptor kpnb1 and its potential as an anticancer therapeutic target. Crit Rev Eukaryot Gene Expr. 2013; 23: 1-10.
    • (2013) Crit Rev Eukaryot Gene Expr , vol.23 , pp. 1-10
    • van der Watt, P.J.1    Stowell, C.L.2    Leaner, V.D.3
  • 136
    • 84873527068 scopus 로고    scopus 로고
    • The functional role of the novel biomarker karyopherin a 2 (KPNA2) in cancer
    • Christiansen A, Dyrskjøt L. The functional role of the novel biomarker karyopherin a 2 (KPNA2) in cancer. Cancer Lett. 2013; 331: 18-23.
    • (2013) Cancer Lett , vol.331 , pp. 18-23
    • Christiansen, A.1    Dyrskjøt, L.2
  • 137
    • 84886102006 scopus 로고    scopus 로고
    • High ran level is correlated with poor prognosis in patients with colorectal cancer
    • Fan H, Lu Y, Qin H, Zhou Y, Gu Y, Zhou J, et al. High ran level is correlated with poor prognosis in patients with colorectal cancer. Int J Clin Oncol. 2013; 18: 856-63.
    • (2013) Int J Clin Oncol , vol.18 , pp. 856-863
    • Fan, H.1    Lu, Y.2    Qin, H.3    Zhou, Y.4    Gu, Y.5    Zhou, J.6
  • 138
    • 0032911885 scopus 로고    scopus 로고
    • The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin ß-dependent nuclear localization signals
    • Truant R, Cullen BR. The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin ß-dependent nuclear localization signals. Mol Cell Biol. 1999; 19: 1210-7.
    • (1999) Mol Cell Biol , vol.19 , pp. 1210-1217
    • Truant, R.1    Cullen, B.R.2
  • 139
    • 84881228732 scopus 로고    scopus 로고
    • Cell type-specific nuclear pores: A case in point for context-dependent stoichiometry of molecular machines
    • Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, et al. Cell type-specific nuclear pores: A case in point for context-dependent stoichiometry of molecular machines. Mol Syst Biol. 2013; 9:648.
    • (2013) Mol Syst Biol , vol.9 , pp. 648
    • Ori, A.1    Banterle, N.2    Iskar, M.3    Andrés-Pons, A.4    Escher, C.5    Khanh Bui, H.6
  • 140
    • 78449301679 scopus 로고    scopus 로고
    • Inflicting controlled nonthermal damage to subcellular structures by laser-activated gold nanoparticles
    • Krpetic Z, Nativo P, See V, Prior IA, Brust M, Volk M. Inflicting controlled nonthermal damage to subcellular structures by laser-activated gold nanoparticles. Nano Lett. 2010; 10: 4549-54.
    • (2010) Nano Lett. , vol.10 , pp. 4549-4554
    • Krpetic, Z.1    Nativo, P.2    See, V.3    Prior, I.A.4    Brust, M.5    Volk, M.6
  • 141
    • 84910011032 scopus 로고    scopus 로고
    • Recent developments in nucleic acid delivery with polyethylenimines
    • Neuberg P, Kichler A. Recent developments in nucleic acid delivery with polyethylenimines. Adv Genet. 2014; 88: 263-88.
    • (2014) Adv Genet , vol.88 , pp. 263-288
    • Neuberg, P.1    Kichler, A.2
  • 142
    • 34347375300 scopus 로고    scopus 로고
    • Direct interorganellar transfer of iron from endosome to mitochondrion
    • Sheftel AD, Zhang AS, Brown C, Shirihai OS, Ponka P. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood. 2007; 110: 125-32.
    • (2007) Blood , vol.110 , pp. 125-132
    • Sheftel, A.D.1    Zhang, A.S.2    Brown, C.3    Shirihai, O.S.4    Ponka, P.5
  • 143
    • 84871981690 scopus 로고    scopus 로고
    • Superior penetration and retention behavior of 50 nm gold nanoparticles in tumors
    • Huo S, Ma H, Huang K, Liu J, Wei T, Jin S, et al. Superior penetration and retention behavior of 50 nm gold nanoparticles in tumors. Cancer Res. 2013; 73: 319-30.
    • (2013) Cancer Res , vol.73 , pp. 319-330
    • Huo, S.1    Ma, H.2    Huang, K.3    Liu, J.4    Wei, T.5    Jin, S.6
  • 144
    • 84899560914 scopus 로고    scopus 로고
    • Polypyrrole-coated chainlike gold nanoparticle architectures with the 808 nm photothermal transduction efficiency up to 70%
    • Lin M, Guo C, Li J, Zhou D, Liu K, Zhang X, et al. Polypyrrole-coated chainlike gold nanoparticle architectures with the 808 nm photothermal transduction efficiency up to 70%. ACS Appl Mater Interfaces. 2014; 6: 5860-8.
    • (2014) ACS Appl Mater Interfaces , vol.6 , pp. 5860-5868
    • Lin, M.1    Guo, C.2    Li, J.3    Zhou, D.4    Liu, K.5    Zhang, X.6
  • 145
    • 84883257899 scopus 로고    scopus 로고
    • Photolabile plasmonic vesicles assembled from amphiphilic gold nanoparticles for remote-controlled traceable drug delivery
    • Song J, Fang Z, Wang C, Zhou J, Duan B, Pu L, et al. Photolabile plasmonic vesicles assembled from amphiphilic gold nanoparticles for remote-controlled traceable drug delivery. Nanoscale. 2013; 5: 5816-24.
    • (2013) Nanoscale , vol.5 , pp. 5816-5824
    • Song, J.1    Fang, Z.2    Wang, C.3    Zhou, J.4    Duan, B.5    Pu, L.6


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