Inhibition of xenograft tumor growth in mice by gold nanoparticle-assisted delivery of short hairpin RNAs against Mcl-1L

Journal of Biotechnology

Volumn 156, Issue 2, 2011, Pages 89-94

  Ryou, Sang Mi ^a   Park, Mira ^a   Kim, Jong Myung ^b   Jeon, Che Ok ^b   Yun, Cheol Hui ^c   Han, Seung Hyun ^c   Kim, Si Wouk ^d   Lee, Younghoon ^e   Kim, Sudeok ^b   Han, Min Su ^b   Bae, Jeehyeon ^a   Lee, Kangseok ^b  

^a CHA University   (South Korea)

^b Chung Ang University   (South Korea)

^c Seoul National University   (South Korea)

^d Chosun University   (South Korea)

^e Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Gold nanoparticle assisted gene delivery system (AuNP GDS); Mcl 1; Short hairpin RNAs (shRNAs); Xenograft tumor

Indexed keywords

ANIMAL MODEL; ANTI-TUMOR ACTIVITIES; CULTURED HUMAN CELL; DNA OLIGONUCLEOTIDES; FUNCTIONALIZED; GENE DELIVERY SYSTEMS; GOLD NANOPARTICLES; IN-VITRO; LIVING SYSTEMS; MCL-1; MOUSE MODELS; SHORT HAIRPIN RNA; SHORT HAIRPIN RNAS (SHRNAS); SMALL RNA; THERAPEUTIC USE; TUMOR CELLS; TUMOR GROWTH; XENOGRAFT TUMOR;

BIOSYNTHESIS; CELL DEATH; GENE THERAPY; GENE TRANSFER; GOLD; MAMMALS; NANOPARTICLES; NUCLEIC ACIDS; OLIGONUCLEOTIDES;

TUMORS;

GOLD NANOPARTICLE; MESSENGER RNA; PROTEIN; PROTEIN MCL 1L; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RNA SYNTHESIS; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GOLD; HUMANS; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; RNA, SMALL INTERFERING;

ANIMALIA; MUS;

EID: 80054014120     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2011.07.037     Document Type: Article

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