Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Santoni, Giorgio ^a   Cardinali, Claudio ^a,b   Morelli, Beatrice ^a,b   Santoni, Matteo ^c   Nabissi, Massimo ^a   Amantini, Consuelo ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Caspase 1; DAMPs; IL 1 ; Inflammasome; Innate immunity; Ion channels; PAMPs; PRRs; TLRs; TRP channels

Indexed keywords

CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PATTERN RECOGNITION RECEPTOR; PROCASPASE 1; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR LIGAND; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 2; ION CHANNEL; PATHOGEN ASSOCIATED MOLECULAR PATTERN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CALCIUM SIGNALING; CELL VOLUME; CENTRAL NERVOUS SYSTEM; DANGER ASSOCIATED MOLECULAR PATTERN; ENZYME ACTIVATION; HUMAN; IMMUNOCOMPETENT CELL; INFLAMMATION; INNATE IMMUNITY; ION TRANSPORT; MICROGLIA; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; OSMOTIC STRESS; PARKINSON DISEASE; PATHOGEN ASSOCIATED MOLECULAR PATTERN; PERIPHERAL NERVOUS SYSTEM; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; SENSITIZATION; SENSORY NERVE CELL; ANIMAL; CYTOLOGY; IMMUNE SYSTEM; METABOLISM;

ANIMALS; HUMANS; IMMUNE SYSTEM; INFLAMMASOMES; ION CHANNELS; PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES; RECEPTORS, PATTERN RECOGNITION; SENSORY RECEPTOR CELLS;

EID: 84924167508     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0239-2     Document Type: Article

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