Nociceptors are interleukin-1β sensors

Journal of Neuroscience

Volumn 28, Issue 52, 2008, Pages 14062-14073

  Binshtok, Alexander M ^a   Wang, Haibin ^a   Zimmermann, Katharina ^b   Amaya, Fumimasa ^a   Vardeh, Daniel ^a   Shi, Lin ^a   Brenner, Gary J ^a   Ji, Ru Rong ^c   Bean, Bruce P ^d   Woolf, Clifford J ^a   Samad, Tarek A ^a,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e PFIZER INC   (United States)

Author keywords

Dorsal root ganglion; Excitability; Inflammation; Interleukin; Nociception; Sodium channel

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; TETRODOTOXIN; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; INTERMEDIATE FILAMENT PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; PERIPHERIN; PYRIDINE DERIVATIVE; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXCITABILITY; INFLAMMATION; MALE; NOCICEPTION; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; TISSUE; ACTION POTENTIAL; ANIMAL; BIOPHYSICS; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; METHODOLOGY; NONMYELINATED NERVE; PATCH CLAMP; PHYSIOLOGY; SENSORY RECEPTOR; SPINAL GANGLION; SPRAGUE DAWLEY RAT; STIMULATION; TIME;

ACTION POTENTIALS; ANIMALS; BIOPHYSICS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GANGLIA, SPINAL; IMIDAZOLES; INTERLEUKIN-1BETA; INTERMEDIATE FILAMENT PROTEINS; MALE; MEMBRANE GLYCOPROTEINS; NERVE FIBERS, UNMYELINATED; NERVE TISSUE PROTEINS; NOCICEPTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PATCH-CLAMP TECHNIQUES; PHYSICAL STIMULATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TIME FACTORS;

EID: 58149387593     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3795-08.2008     Document Type: Article

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