Expression of transient receptor potential vanilloid receptor 1 and toll-like receptor 4 in aggressive periodontitis and in chronic periodontitis

Journal of Periodontal Research

Volumn 46, Issue 4, 2011, Pages 475-482

  Ozturk A ^a   Yildiz, L ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Capsaicin; Gingiva; Neurogenic inflammation; Toll like receptor 4 (TLR4); Transient receptor potential vanilloid receptor 1 (TRPV1)

Indexed keywords

TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4; TRPV1 PROTEIN, HUMAN; VANILLOID RECEPTOR;

ADULT; AGGRESSIVE PERIODONTITIS; ARTICLE; CAPILLARY; CHRONIC PERIODONTITIS; COMPARATIVE STUDY; CONNECTIVE TISSUE; DOWN REGULATION; ENDOTHELIUM CELL; EPITHELIUM CELL; FIBROBLAST; GINGIVA; GINGIVA BLEEDING; GINGIVITIS; HUMAN; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; METABOLISM; PATHOLOGY; PERIODONTAL DISEASE; PERIODONTAL POCKET; VASCULAR ENDOTHELIUM;

ADULT; AGGRESSIVE PERIODONTITIS; CAPILLARIES; CHRONIC PERIODONTITIS; CONNECTIVE TISSUE; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EPITHELIAL CELLS; FIBROBLASTS; GINGIVA; GINGIVAL HEMORRHAGE; GINGIVITIS; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINOCYTES; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; TOLL-LIKE RECEPTOR 4; TRPV CATION CHANNELS;

EID: 79959620035     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2011.01363.x     Document Type: Article

References (43)

1. Downing JE, Miyan JA. Neural immunoregulation: emerging roles for nerves in immune homeostasis and disease. Immunol Today 2000;21:281-289.
2. Kaplin A, Bartner S. Reciprocal communication between the nervous and immune systems: crosstalk, back-talk and motivational speeches. Int Rev Psychiatry 2005;17:439-441.
3. Bayliss WM. On the origin from the spinal cord of the vasodilator fibres of the hind limb and on the nature of these fibres. J Phyiol (Lond) 1901;26:173-209.
4. Jancsó N, Jancsó-Gábor A, Szolcsányi J. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin. Br J Pharmacol Chemother 1967;31:138-151.
5. Richardson JD, Vasko MR. Cellular mechanisms of neurogenic inflammation. J Pharmacol Exp Ther 2002;302:839-845.
6. Malmberg AB, Mizisin AP, Calcutt NA, von Stein T, Robbins WR, Bley KR. Reduced heatsensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch. Pain 2004;111:360-367.
7. Cateria MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-824.
8. Szallasi A, Dimarzo V. New perspectives on enigmatic vanilloid receptors. Trends Neurosci 2000;23:491-497.
9. Roosterman D, Goerge T, Schneider SW, Bunnett NW, Steinhoff M. Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiol Rev 2006;86:1309-1379.
10. Kimberly CL, Byers MR. Inflammation of rat molar pulp and periodontium causes increased calcitonin gene-related peptide and axonal sprouting. Anat Rec 1988;222:289-300.
11. Gyorfi A, Fazekas A, Rosivall L. Neurogenic inflammation and the oral mucosa. J Clin Periodontol 1992;19:731-736.
12. Gyorfi A, Fazekas A, Suba ZS, Ender F, Rosivall L. Neurogenic component in ligature-induced periodontitis in the rat. J Clin Periodontol 1994;21:601-605.
13. Kondo T, Kido MA, Kiyoshima T, Yamaza T, Tanaka T. An immunohistochemical and monastral blue-vascular labelling study on the involvement of capsaicin-sensitive sensory innervation of the junctional epithelium in neurogenic plasma extravasation in the rat gingiva. Arch Oral Biol 1995;40:931-940.
14. Avellan NL, Kemppainen P, Tervahartiala T, Vilppola P, Forster C, Sorsa T. Capsaicin-induced local elevations in collagenase-2 (matrix metalloproteinase-8) levels in human gingival crevice fluid. J Periodontal Res 2006;41:33-38.
15. Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-2088.
16. Takeuchi O, Hoshino K, Kawai T et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 1999;11:443-451.
17. Mori Y, Yoshimura A, Ukai T, Lien E, Espevik T, Hara Y. Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiol Immunol 2003;18:54-58.
18. Ren L, Leung WK, Darveau RP, Jin L. The expression profile of lipopolysaccharide-binding protein, membrane-bound CD14, and toll-like receptors 2 and 4 in chronic periodontitis. J Periodontol 2005;76:1950-1959.
19. Wang PL, Ohura K, Fujii T et al. DNA microarray analysis of human gingival fibroblasts from healthy and inflammatory gingival tissues. Biochem Biophys Res Commun 2003;305:970-973.
20. Medzhitov R, Janeway C Jr. The Toll receptor family and microbial recognition. Trends Microbiol 2000;8:452-456.
21. Wang PL, Azuma Y, Shinohara M, Ohura K. Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts. Biochem Biophys Res Commun 2000;273:1161-1167.
22. Qureshi ST, Lariviere L, Leveque G et al. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J Exp Med 1999;189:615-625.
23. Nomura F, Akashi S, Sakao Y et al. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J Immunol 2000;164:3476-3479.
24. Wadachi R, Hargreaves KM. Trigeminal nociceptors express TLR-4 and CD14: a mechanism for pain due to infection. J Dent Res 2006;85:49-53.
25. Seymour GJ, Gemmell E, Walsh LJ, Powell RN. Immunohistological analysis of experimental gingivitis in humans. Clin Exp Immunol 1988;71:132-137.
26. Yamazaki K, Ohsawa Y, Yoshie H. Elevated proportion of natural killer T cells in periodontitis lesions: a common feature of chronic inflammatory diseases. Am J Pathol 2001;158:1391-1398.
27. Academy of Periodontology. 1999 International Workshop for a classification of periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
28. Krajewska M, Krajewski S, Epstein JL et al. Immunohistochemical analysis of bcl-2, bax, bcl-X and mcl-1 expression in prostate cancers. Am J Pathol 1996;148:1567-1576.
29. Premkumar LS, Ahern GP. Induction of vanilloid receptor channel activity by protein kinase C. Nature 2000;408:985-990.
30. Zygmunt PM, Petersson J, Andersson DA et al. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 1999;400:452-457.
31. Hwang SW, Cho H, Kwak J et al. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A 2000;97:6155-6160.
32. Lundy FT, Linden GJ. Neuropeptides and neurogenic mechanisms in oral and periodontal inflammation. Crit Rev Oral Biol Med 2004;15:82-98.
33. Bodo E, Kovacs I, Telek A et al. Vanilloid receptor-1 (VR1) is widely expressed on various epithelial and mesenchymal cell types of human skin. J Invest Dermatol 2004;123:410-413.
34. Inoue K, Koizumi S, Fuziwara S, Denda S, Denda M. Functional vanilloid receptors in cultured normal human epidermal keratinocytes. Biochem Biophys Res Commun 2002;291:124-129.
35. Stander S, Moormann C, Schumacher M et al. Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 2004;13:129-139.
36. Armitage GC, Cullinan MP, Seymour GJ. Comparative biology of chronic and aggressive periodontitis: introduction. Periodontol 2000 2010;53:7-11.
37. Ford PJ, Gamonal J, Seymour GJ. Immunological differences and similarities between chronic periodontitis and aggressive periodontitis. Periodontol 2000 2010;53:111-123.
38. Schenkein HA. Host responses in maintaining periodontal health and determining periodontal disease. Periodontol 2000 2006;40:77-93.
39. Muthukuru M, Jotwani R, Cutler CW. Oral mucosal endotoxin tolerance induction in chronic periodontitis. Infect Immun 2005;73:687-694.
40. Beklen A, Hukkanen M, Richardson R, Konttinen YT. Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis. Oral Microbiol Immunol 2008;23:425-431.
41. Wang PL, Oido-Mori M, Fujii T et al. Heterogeneous expression of Toll-like receptor 4 and downregulation of Toll-like receptor 4 expression on human gingival fibroblasts by Porphyromonas gingivalis lipopolysaccharide. Biochem Biophys Res Commun 2001;288:863-867.
42. Deschner J, Singhal A, Long P, Liu CC, Piesco N, Agarwal S. Cleavage of CD14 and LBP by a protease from Prevotella intermedia. Arch Microbiol 2003;179:430-436.
43. Sugawara S, Nemoto E, Tada H, Miyake K, Imamura T, Takada H. Proteolysis of human monocyte CD14 by cysteine proteinases (gingipains) from Porphyromonas gingivalis leading to lipopolysaccharide hyporesponsiveness. J Immunol 2000;165:411-418.