Humans are more sensitive to the taste of linoleic and α-linolenic than oleic acid

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 308, Issue 5, 2015, Pages G442-G449

  Running, Cordelia A ^a   Mattes, Richard D ^b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Fat detection; Fat taste; Nonesterified fatty acids; Unsaturation

Indexed keywords

FATTY ACID; LINOLEIC ACID; LINOLENIC ACID; OLEIC ACID; EMULSION;

ADULT; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; EMULSION; FAT INTAKE; FATTY ACID DESATURATION; FEMALE; FLOW KINETICS; FORCED CHOICE METHOD; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; LEARNING; MALE; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SHEAR RATE; SOLUTION AND SOLUBILITY; TASTE; TASTE ACUITY; VISCOSITY; ADOLESCENT; CHEMISTRY; CLINICAL TRIAL; DRUG EFFECTS; MIDDLE AGED; MOUTH MUCOSA; PERCEPTIVE THRESHOLD; PHARMACOLOGY; PHYSIOLOGY; RANDOMIZATION;

ADOLESCENT; ADULT; ALPHA-LINOLENIC ACID; CROSS-OVER STUDIES; EMULSIONS; FEMALE; HUMANS; LINOLEIC ACID; MALE; MIDDLE AGED; MOUTH MUCOSA; OLEIC ACID; RANDOM ALLOCATION; SENSORY THRESHOLDS; TASTE;

EID: 84924039644     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00394.2014     Document Type: Article

References (37)

1. American Society for Testing and Materials International. Standard Practice for Determination of Odor and Taste Thresholds By a Forced- Choice Ascending Concentration Series Method of Limits. West Conshohocken, PA: ASTM, 2011. [Standard E679-04 (2011)]
2. Block G, Gillespie C, Rosenbaum EH, Jenson C. A rapid food screener to assess fat and fruit and vegetable intake. Am J Prev Med 18: 284–288, 2000.
3. Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278: 11303–11311, 2003.
4. Cartoni C, Yasumatsu K, Ohkuri T, Shigemura N, Yoshida R, Godinot N, le Coutre J, Ninomiya Y, Damak S. Taste preference for fatty acids is mediated by GPR40 and GPR120. J Neurosci 30: 8376–8382, 2010.
5. Chale-Rush A, Burgess JR, Mattes RD. Evidence for human orosensory (taste?) sensitivity to free fatty acids. Chem Senses 32: 423–431, 2007.
6. Chale-Rush A, Burgess JR, Mattes RD. Multiple routes of chemosensitivity to free fatty acids in humans. Am J Physiol Gastrointest Liver Physiol 292: G1206–G1212, 2007.
7. Chen CS, Bench EM, Allerton TD, Schreiber AL, Arceneaux KP 3rd, Primeaux SD. Preference for linoleic acid in obesity-prone and obesityresistant rats is attenuated by the reduction of CD36 on the tongue. Am J Physiol Regul Integr Comp Physiol 305: R1346–R1355, 2013.
8. Chevrot M, Bernard A, Ancel D, Buttet M, Martin C, Abdoul-Azize S, Merlin JF, Poirier H, Niot I, Khan NA, Passilly-Degrace P, Besnard P. Obesity alters the gustatory perception of lipids in the mouse: plausible involvement of lingual CD36. J Lipid Res 54: 2485–2494, 2013.
9. Dijkstra AJ. Modification processes and food uses. In: The Lipid Handbook, edited by Gunstone FD, Harwood JL, Dijkstra AJ. Boca Raton, FL: CRC, 2007, p. 264.
10. Galindo MM, Voigt N, Stein J, van Lengerich J, Raguse JD, Hofmann T, Meyerhof W, Behrens M. G protein-coupled receptors in human fat taste perception. Chem Senses 37: 123–139, 2012.
11. Gilbertson TA, Khan NA. Cell signaling mechanisms of oro-gustatory detection of dietary fat: advances and challenges. Prog Lipid Res 53: 82–92, 2014.
12. Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR 120. Nat Med 11: 90–94, 2005.
13. Holman R, Elmer O. The rates of oxidation of unsaturated fatty acids and esters. J Am Oil Chem Soc 24: 127–129, 1947.
14. Kampf JP, Cupp D, Kleinfeld AM. Different mechanisms of free fatty acid flip-flop and dissociation revealed by temperature and molecular species dependence of transport across lipid vesicles. J Biol Chem 281: 21566–21574, 2006.
15. Lawless HT, Heymann H. Sensory Evaluation of Food: Principles and Practices. New York: Springer, 2010.
16. Martin C, Passilly-Degrace P, Gaillard D, Merlin JF, Chevrot M, Besnard P. The lipid-sensor candidates CD36 and GPR120 are differentially regulated by dietary lipids in mouse taste buds: impact on spontaneous fat preference. Plos One 6, 2011.
17. Poette J, Mekoué J, Neyraud E, Berdeaux O, Renault A, Guichard E, Genot C, Feron G. Fat sensitivity in humans: oleic acid detection threshold is linked to saliva composition and oral volume. Flavour Fragrance J 29: 39–49, 2014.
18. Running CA. High false positive rates in common sensory threshold tests. Atten Percept Psychophys. In press.
19. Running CA, Mattes RD. Different oral sensitivities to and sensations of short, medium, and long chain fatty acids in humans. Am J Physiol Gastrointest Liver Physiol 307: G381–G389, 2014.
20. Running CA, Mattes RD, Tucker RM. Fat taste in humans: sources of within- and between-subject variability. Prog Lipid Res 52: 438–445, 2013.
21. Smeets AJ, Westerterp-Plantenga MS. Satiety and substrate mobilization after oral fat stimulation. Br J Nutr 95: 795–801, 2006.
22. Smith CH, Logemann JA, Burghardt WR, Carrell TD, Zecker SG. Oral sensory discrimination of fluid viscosity. Dysphagia 12: 68–73, 1997.
23. Stewart JE, Feinle-Bisset C, Golding M, Delahunty C, Clifton PM, Keast RS. Oral sensitivity to fatty acids, food consumption and BMI in human subjects. Br J Nutr 104: 145–152, 2010.
24. Stewart JE, Keast RS. Recent fat intake modulates fat taste sensitivity in lean and overweight subjects. Int J Obes 36: 834–842, 2012.
25. Stewart JE, Newman LR, Keast RS. Oral sensitivity to oleic acid is associated with fat intake and body mass index. Clin Nutr 30: 838–844, 2011.
26. Stewart JE, Seimon RV, Otto B, Keast RS, Clifton PM, Feinle-Bisset C. Marked differences in gustatory and gastrointestinal sensitivity to oleic acid between lean and obese men. Am J Clin Nutr 93: 703–711, 2011.
27. Stokes JR. “Oral” rheology. In: Food Oral Processing: Fundamentals of Eating and Sensory Perception, edited by Chen J, Engelen L. Chicester, UK: Wiley, 2012, p. 227–263.
28. Tittelbach TJ, Mattes RD. Oral stimulation influences postprandial triacylglycerol concentrations in humans: nutrient specificity. J Am Coll Nutr 20: 485–493, 2001.
29. Tucker RM, Edlinger C, Craig BA, Mattes RD. Associations between BMI and fat taste sensitivity in humans. Chem Senses 39: 349–357, 2014.
30. Tucker RM, Laguna L, Quinn R, Mattes RD. The effect of short, daily oral exposure on non-esterified fatty acid sensitivity. Chemosens Percept 6: 78–85, 2013.
31. Tucker RM, Mattes RD. Influences of repeated testing on nonesterified fatty acid taste. Chem Senses 38: 325–332, 2013.
32. Tucker RM, Mattes RD, Running CA. Mechanisms and effects of “fat taste” in humans. Biofactors 40: 313–326, 2014.
33. US Department of Agriculture. Dietary Saturated Fat and Cardiovascular Health: A Review of the Evidence (Online). Center for Nutrition Policy and Promotion. http://www.cnpp.usda.gov/Publications/NutritionInsights/Insight44.pdf, 2011 [6 Feb 2014].
34. US Department of Agriculture. What Is the Effect of Dietary Intake of Monounsaturated Fatty Acids (MUFA) When Substituted for Saturated Fatty Acids on Increased Risk of Cardiovascular Disease and Type 2 Diabetes, Including Intermediate Markers Such as Lipid and Lipoprotein Levels and Inflammation? US Department of Health and Human Services. Nutrition Evidence Library. http://www.nel.gov/evidence.cfm?evidence:summary_id250137, 2013 [30 Sept 2013].
35. US Department of Agriculture. What Is the Effect of Dietary PUFA Intake on Health and Intermediate Health Outcomes? US Department of Health and Human Services. Nutrition Evidence Library. http://www.nel.gov/evidence.cfm?evidence:summary_id250137, 2013 [30 Sept 2013].
36. Xiao C, Giacca A, Carpentier A, Lewis GF. Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucosestimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans. Diabetologia 49: 1371–1379, 2006.
37. Zhang XJ, Zhou LH, Ban X, Liu DX, Jiang W, Liu XM. Decreased expression of CD36 in circumvallate taste buds of high-fat diet induced obese rats. Acta Histochem 113: 663–667, 2011.