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Volumn 10, Issue 2, 2015, Pages

Evaluation of canonical siRNA and Dicer substrate RNA for inhibition of hepatitis C virus genome replication - A comparative study

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DICER SUBSTRATE SMALL INTERFERING RNA; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 5' UNTRANSLATED REGION; VIRAL PROTEIN; VIRUS RNA;

EID: 84923374490     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117742     Document Type: Article
Times cited : (15)

References (55)
  • 1
    • 84855231089 scopus 로고    scopus 로고
    • Hepatitis C virus treatment pre- and post-liver transplantation
    • PMID: 22212582
    • Roche B, Samuel D (2012) Hepatitis C virus treatment pre- and post-liver transplantation. Liver Int 32 Suppl 1: 120-128. doi: 10.1111/j.1478-3231.2011.02714.x PMID: 22212582
    • (2012) Liver Int , vol.32 , pp. 120-128
    • Roche, B.1    Samuel, D.2
  • 2
    • 84857144025 scopus 로고    scopus 로고
    • The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007
    • PMID: 22351712
    • Ly KN, Xing J, Klevens RM, Jiles RB, Ward JW, et al. (2012) The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007. Ann Intern Med 156: 271-278. doi: 10.7326/0003-4819-156-4-201202210-00004 PMID: 22351712
    • (2012) Ann Intern Med , vol.156 , pp. 271-278
    • Ly, K.N.1    Xing, J.2    Klevens, R.M.3    Jiles, R.B.4    Ward, J.W.5
  • 3
    • 78751621217 scopus 로고    scopus 로고
    • Evolving epidemiology of hepatitis C virus
    • PMID: 21091831
    • Lavanchy D (2011) Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect 17: 107-115. doi: 10.1111/j.1469-0691.2010.03432.x PMID: 21091831
    • (2011) Clin Microbiol Infect , vol.17 , pp. 107-115
    • Lavanchy, D.1
  • 4
    • 79953797938 scopus 로고    scopus 로고
    • An overview of HCV molecular biology, replication and immune responses
    • PMID: 21477382
    • Ashfaq UA, Javed T, Rehman S, Nawaz Z, Riazuddin S (2011) An overview of HCV molecular biology, replication and immune responses. Virol J 8: 161. doi: 10.1186/1743-422X-8-161 PMID: 21477382
    • (2011) Virol J , vol.8 , pp. 161
    • Ashfaq, U.A.1    Javed, T.2    Rehman, S.3    Nawaz, Z.4    Riazuddin, S.5
  • 5
    • 17344381535 scopus 로고    scopus 로고
    • Hepatitis C virus biology
    • PMID: 12655344
    • Giannini C, Bréchot C (2003) Hepatitis C virus biology. Cell Death Differ 10 Suppl 1: S27-38. PMID: 12655344
    • (2003) Cell Death Differ , vol.10 , pp. S27-S38
    • Giannini, C.1    Bréchot, C.2
  • 7
    • 84919460742 scopus 로고    scopus 로고
    • The impact of the new antiviral regimens on patient reported outcomes and health economics of patients with chronic hepatitis C
    • Younossi Z, Henry L (2014) The impact of the new antiviral regimens on patient reported outcomes and health economics of patients with chronic hepatitis C. Dig Liver Dis 46S5: S186-S196.
    • (2014) Dig Liver Dis , vol.46 , pp. S186-S196
    • Younossi, Z.1    Henry, L.2
  • 8
    • 71249099403 scopus 로고    scopus 로고
    • RNAi as a new therapeutic strategy against HCV
    • PMID: 19729057
    • Khaliq S, Khaliq SA, Zahur M, Ijaz B, Jahan S, et al. (2010) RNAi as a new therapeutic strategy against HCV. Biotechnol Adv 28: 27-34. doi: 10.1016/j.biotechadv.2009.08.004 PMID: 19729057
    • (2010) Biotechnol Adv , vol.28 , pp. 27-34
    • Khaliq, S.1    Khaliq, S.A.2    Zahur, M.3    Ijaz, B.4    Jahan, S.5
  • 9
    • 84897510065 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus in chimeric mice by short synthetic hairpin RNAs: Sequence analysis of surviving virus shows added selective pressure of combination therapy
    • PMID: 24478422
    • Dallas A, Ilves H, Ma H, Chin DJ, Maclachlan I, et al. (2014) Inhibition of hepatitis C virus in chimeric mice by short synthetic hairpin RNAs: sequence analysis of surviving virus shows added selective pressure of combination therapy. J Virol 88: 4647-4656. doi: 10.1128/JVI.00105-14 PMID: 24478422
    • (2014) J Virol , vol.88 , pp. 4647-4656
    • Dallas, A.1    Ilves, H.2    Ma, H.3    Chin, D.J.4    Maclachlan, I.5
  • 10
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • PMID: 9486653
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811. PMID: 9486653
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5
  • 11
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • PMID: 12110901
    • Hannon GJ (2002) RNA interference. Nature 418: 244-251. PMID: 12110901
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 12
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • PMID: 11792820
    • Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K (2001) Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci 114: 4557-4565. PMID: 11792820
    • (2001) J Cell Sci , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuschl, T.4    Weber, K.5
  • 13
    • 78650624101 scopus 로고    scopus 로고
    • RNA interference in the clinic: Challenges and future directions
    • PMID: 21160526
    • Pecot C V, Calin GA, Coleman RL, Lopez-Berestein G, Sood AK (2011) RNA interference in the clinic: challenges and future directions. Nat Rev Cancer 11: 59-67. doi: 10.1038/nrc2966 PMID: 21160526
    • (2011) Nat Rev Cancer , vol.11 , pp. 59-67
    • Pecot, C.V.1    Calin, G.A.2    Coleman, R.L.3    Lopez-Berestein, G.4    Sood, A.K.5
  • 14
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • PMID: 11726523
    • Elbashir SM, Martinez J, Patkaniowska a, Lendeckel W, Tuschl T (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 20: 6877-6888. PMID: 11726523
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 15
    • 0037452625 scopus 로고    scopus 로고
    • Interference of hepatitis C virus RNA replication by short interfering RNAs
    • PMID: 12566571
    • Kapadia SB, Brideau-Andersen A, Chisari F V (2003) Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc Natl Acad Sci U S A 100: 2014-2018. PMID: 12566571
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2014-2018
    • Kapadia, S.B.1    Brideau-Andersen, A.2    Chisari, F.V.3
  • 16
    • 0037422607 scopus 로고    scopus 로고
    • Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
    • PMID: 12518066
    • Randall G, Grakoui A, Rice CM (2003) Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc Natl Acad Sci U S A 100: 235-240. PMID: 12518066
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 235-240
    • Randall, G.1    Grakoui, A.2    Rice, C.M.3
  • 17
    • 0344321890 scopus 로고    scopus 로고
    • RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
    • PMID: 12594341
    • Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG, et al. (2003) RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Natl Acad Sci U S A 100: 2783-2788. PMID: 12594341
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2783-2788
    • Wilson, J.A.1    Jayasena, S.2    Khvorova, A.3    Sabatinos, S.4    Rodrigue-Gervais, I.G.5
  • 18
    • 13844281898 scopus 로고    scopus 로고
    • Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
    • PMID: 15619617
    • Kim D-H, Behlke M a, Rose SD, Chang M-S, Choi S, et al. (2005) Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol 23: 222-226. PMID: 15619617
    • (2005) Nat Biotechnol , vol.23 , pp. 222-226
    • Kim, D.-H.1    Behlke, M.A.2    Rose, S.D.3    Chang, M.-S.4    Choi, S.5
  • 19
    • 84856020342 scopus 로고    scopus 로고
    • Dicer-substrate siRNA inhibits tumor necrosis factor alpha secretion in Kupffer cells in vitro: In vivo targeting of Kupffer cells by siRNA-liposomes
    • PMID: 21933712
    • Pichu S, Krishnamoorthy S, Zhang B, Jing Y, Shishkov A, et al. (2012) Dicer-substrate siRNA inhibits tumor necrosis factor alpha secretion in Kupffer cells in vitro: In vivo targeting of Kupffer cells by siRNA-liposomes. Pharmacol Res 65: 48-55. doi: 10.1016/j.phrs.2011.09.001 PMID: 21933712
    • (2012) Pharmacol Res , vol.65 , pp. 48-55
    • Pichu, S.1    Krishnamoorthy, S.2    Zhang, B.3    Jing, Y.4    Shishkov, A.5
  • 20
    • 84880213957 scopus 로고    scopus 로고
    • Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants
    • PMID: 23620279
    • Snead NM, Wu X, Li A, Cui Q, Sakurai K, et al. (2013) Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants. Nucleic Acids Res 41: 6209-6221. doi: 10.1093/nar/gkt200 PMID: 23620279
    • (2013) Nucleic Acids Res , vol.41 , pp. 6209-6221
    • Snead, N.M.1    Wu, X.2    Li, A.3    Cui, Q.4    Sakurai, K.5
  • 22
    • 33750062855 scopus 로고    scopus 로고
    • siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations
    • PMID: 17052275
    • Konishi M, Wu CH, Kaito M, Hayashi K, Watanabe S, et al. (2006) siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations. J Viral Hepat 13: 756-761. PMID: 17052275
    • (2006) J Viral Hepat , vol.13 , pp. 756-761
    • Konishi, M.1    Wu, C.H.2    Kaito, M.3    Hayashi, K.4    Watanabe, S.5
  • 24
    • 32444435210 scopus 로고    scopus 로고
    • Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry
    • PMID: 16439530
    • Tscherne DM, Jones CT, Evans MJ, Lindenbach BD, McKeating JA, et al. (2006) Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry. J Virol 80: 1734-1741. PMID: 16439530
    • (2006) J Virol , vol.80 , pp. 1734-1741
    • Tscherne, D.M.1    Jones, C.T.2    Evans, M.J.3    Lindenbach, B.D.4    McKeating, J.A.5
  • 25
    • 0036893332 scopus 로고    scopus 로고
    • Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
    • PMID: 12438626
    • Blight KJ, McKeating JA, Rice CM (2002) Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J Virol 76: 13001-13014. PMID: 12438626
    • (2002) J Virol , vol.76 , pp. 13001-13014
    • Blight, K.J.1    McKeating, J.A.2    Rice, C.M.3
  • 26
    • 84876213842 scopus 로고    scopus 로고
    • The C terminus of NS5A domain II is a key determinant of hepatitis C virus genome replication, but is not required for virion assembly and release
    • PMID: 23324467
    • Ross-Thriepland D, Amako Y, Harris M (2013) The C terminus of NS5A domain II is a key determinant of hepatitis C virus genome replication, but is not required for virion assembly and release. J Gen Virol 94: 1009-1018. doi: 10.1099/vir.0.050633-0 PMID: 23324467
    • (2013) J Gen Virol , vol.94 , pp. 1009-1018
    • Ross-Thriepland, D.1    Amako, Y.2    Harris, M.3
  • 27
    • 69549113556 scopus 로고    scopus 로고
    • Role of oxysterol binding protein in hepatitis C virus infection
    • PMID: 19570870
    • Amako Y, Sarkeshik A, Hotta H, Yates J, Siddiqui A (2009) Role of oxysterol binding protein in hepatitis C virus infection. J Virol 83: 9237-9246. doi: 10.1128/JVI.00958-09 PMID: 19570870
    • (2009) J Virol , vol.83 , pp. 9237-9246
    • Amako, Y.1    Sarkeshik, A.2    Hotta, H.3    Yates, J.4    Siddiqui, A.5
  • 28
    • 22844448088 scopus 로고    scopus 로고
    • Functional polarity is introduced by Dicer processing of short substrate RNAs
    • PMID: 16049023
    • Rose SD, Kim D-H, Amarzguioui M, Heidel JD, Collingwood MA, et al. (2005) Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res 33: 4140-4156. PMID: 16049023
    • (2005) Nucleic Acids Res , vol.33 , pp. 4140-4156
    • Rose, S.D.1    Kim, D.-H.2    Amarzguioui, M.3    Heidel, J.D.4    Collingwood, M.A.5
  • 29
    • 0038719743 scopus 로고    scopus 로고
    • The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling
    • PMID: 12621033
    • Macdonald A, Crowder K, Street A, McCormick C, Saksela K, et al. (2003) The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling. J Biol Chem 278: 17775-17784. PMID: 12621033
    • (2003) J Biol Chem , vol.278 , pp. 17775-17784
    • Macdonald, A.1    Crowder, K.2    Street, A.3    McCormick, C.4    Saksela, K.5
  • 30
    • 84866756978 scopus 로고    scopus 로고
    • Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits
    • PMID: 22319660
    • Mruk DD, Cheng CY (2011) Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits. Spermatogenesis 1: 121-122. PMID: 22319660
    • (2011) Spermatogenesis , vol.1 , pp. 121-122
    • Mruk, D.D.1    Cheng, C.Y.2
  • 31
  • 32
    • 10744219688 scopus 로고    scopus 로고
    • Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
    • PMID: 14769924
    • Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, et al. (2004) Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A 101: 1892-1897. PMID: 14769924
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1892-1897
    • Scacheri, P.C.1    Rozenblatt-Rosen, O.2    Caplen, N.J.3    Wolfsberg, T.G.4    Umayam, L.5
  • 33
    • 0038121109 scopus 로고    scopus 로고
    • Specificity of short interfering RNA determined through gene expression signatures
    • PMID: 12746500
    • Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, et al. (2003) Specificity of short interfering RNA determined through gene expression signatures. Proc Natl Acad Sci U S A 100: 6347-6352. PMID: 12746500
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6347-6352
    • Semizarov, D.1    Frost, L.2    Sarthy, A.3    Kroeger, P.4    Halbert, D.N.5
  • 34
    • 21844438516 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors
    • PMID: 15964661
    • Korf M, Jarczak D, Beger C, Manns MP, Krüger M (2005) Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors. J Hepatol 43: 225-234. PMID: 15964661
    • (2005) J Hepatol , vol.43 , pp. 225-234
    • Korf, M.1    Jarczak, D.2    Beger, C.3    Manns, M.P.4    Krüger, M.5
  • 35
    • 33845549221 scopus 로고    scopus 로고
    • Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes
    • PMID: 17129382
    • Prabhu R, Garry RF, Dash S (2006) Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes. Virol J 3: 100. PMID: 17129382
    • (2006) Virol J , vol.3 , pp. 100
    • Prabhu, R.1    Garry, R.F.2    Dash, S.3
  • 36
    • 0142091755 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus protein expression by RNA interference
    • PMID: 12951263
    • Sen A, Steele R, Ghosh AK, Basu A, Ray R, et al. (2003) Inhibition of hepatitis C virus protein expression by RNA interference. Virus Res 96: 27-35. PMID: 12951263
    • (2003) Virus Res , vol.96 , pp. 27-35
    • Sen, A.1    Steele, R.2    Ghosh, A.K.3    Basu, A.4    Ray, R.5
  • 37
    • 33845623845 scopus 로고    scopus 로고
    • Structural and mechanistic insights into hepatitis C viral translation initiation
    • Fraser CS, Doudna J a (2007) Structural and mechanistic insights into hepatitis C viral translation initiation. NatRevMicrobiol 5: 29-38.
    • (2007) NatRevMicrobiol , vol.5 , pp. 29-38
    • Fraser, C.S.1    Doudna, J.A.2
  • 38
    • 34547123547 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus infection in cell culture by small interfering RNAs
    • PMID: 17505476
    • Chevalier C, Saulnier A, Benureau Y, Fléchet D, Delgrange D, et al. (2007) Inhibition of hepatitis C virus infection in cell culture by small interfering RNAs. Mol Ther 15: 1452-1462. PMID: 17505476
    • (2007) Mol Ther , vol.15 , pp. 1452-1462
    • Chevalier, C.1    Saulnier, A.2    Benureau, Y.3    Fléchet, D.4    Delgrange, D.5
  • 39
    • 84857375929 scopus 로고    scopus 로고
    • Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
    • PMID: 22294662
    • Foster DJ, Barros S, Duncan R, Shaikh S, Cantley W, et al. (2012) Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo. RNA 18: 557-568. doi: 10.1261/rna.031120.111 PMID: 22294662
    • (2012) RNA , vol.18 , pp. 557-568
    • Foster, D.J.1    Barros, S.2    Duncan, R.3    Shaikh, S.4    Cantley, W.5
  • 40
    • 33748987349 scopus 로고    scopus 로고
    • RNA interference effectively inhibits mRNA accumulation and protein expression of hepatitis C virus core and E2 genes in human cells
    • PMID: 16960393
    • Liu M, Ding H, Zhao P, Qin Z-L, Gao J, et al. (2006) RNA interference effectively inhibits mRNA accumulation and protein expression of hepatitis C virus core and E2 genes in human cells. Biosci Biotechnol Biochem 70: 2049-2055. PMID: 16960393
    • (2006) Biosci Biotechnol Biochem , vol.70 , pp. 2049-2055
    • Liu, M.1    Ding, H.2    Zhao, P.3    Qin, Z.-L.4    Gao, J.5
  • 41
    • 33746581711 scopus 로고    scopus 로고
    • Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes
    • PMID: 16775303
    • Liu X, Jiang F, Kalidas S, Smith D, Liu Q (2006) Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes. RNA 12: 1514-1520. PMID: 16775303
    • (2006) RNA , vol.12 , pp. 1514-1520
    • Liu, X.1    Jiang, F.2    Kalidas, S.3    Smith, D.4    Liu, Q.5
  • 42
    • 77954350917 scopus 로고    scopus 로고
    • Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC
    • PMID: 20167638
    • Salomon W, Bulock K, Lapierre J, Pavco P, Woolf T, et al. (2010) Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC. Nucleic Acids Res 38: 3771-3779. doi: 10.1093/nar/gkq055 PMID: 20167638
    • (2010) Nucleic Acids Res , vol.38 , pp. 3771-3779
    • Salomon, W.1    Bulock, K.2    Lapierre, J.3    Pavco, P.4    Woolf, T.5
  • 43
    • 84896076379 scopus 로고    scopus 로고
    • 42- and 63-bp anti-MDR1-siRNAs bearing 2′-OMe modifications in nuclease-sensitive sites induce specific and potent gene silencing
    • PMID: 24561194
    • Gvozdeva O V, Dovydenko IS, Venyaminova AG, Zenkova MA, Vlassov V V, et al. (2014) 42- and 63-bp anti-MDR1-siRNAs bearing 2′-OMe modifications in nuclease-sensitive sites induce specific and potent gene silencing. FEBS Lett 588: 1037-1043. doi: 10.1016/j.febslet.2014.02.015 PMID: 24561194
    • (2014) FEBS Lett , vol.588 , pp. 1037-1043
    • Gvozdeva, O.V.1    Dovydenko, I.S.2    Venyaminova, A.G.3    Zenkova, M.A.4    Vlassov, V.V.5
  • 44
    • 21744462419 scopus 로고    scopus 로고
    • Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone
    • PMID: 15977238
    • Prabhu R, Vittal P, Yin Q, Flemington E, Garry R, et al. (2005) Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone. J Med Virol 76: 511-519. PMID: 15977238
    • (2005) J Med Virol , vol.76 , pp. 511-519
    • Prabhu, R.1    Vittal, P.2    Yin, Q.3    Flemington, E.4    Garry, R.5
  • 45
    • 4143088066 scopus 로고    scopus 로고
    • Suppression of hepatitis C virus replicon by RNA interference directed against the NS3 and NS5B regions of the viral genome
    • PMID: 15322339
    • Takigawa Y, Nagano-Fujii M, Deng L, Hidajat R, Tanaka M, et al. (2004) Suppression of hepatitis C virus replicon by RNA interference directed against the NS3 and NS5B regions of the viral genome. Microbiol Immunol 48: 591-598. PMID: 15322339
    • (2004) Microbiol Immunol , vol.48 , pp. 591-598
    • Takigawa, Y.1    Nagano-Fujii, M.2    Deng, L.3    Hidajat, R.4    Tanaka, M.5
  • 46
    • 18744382144 scopus 로고    scopus 로고
    • Hepatitis C virus replicons escape RNA interference induced by a short interfering RNA directed against the NS5b coding region
    • PMID: 15890944
    • Wilson JA, Richardson CD (2005) Hepatitis C virus replicons escape RNA interference induced by a short interfering RNA directed against the NS5b coding region. J Virol 79: 7050-7058. PMID: 15890944
    • (2005) J Virol , vol.79 , pp. 7050-7058
    • Wilson, J.A.1    Richardson, C.D.2
  • 47
    • 35848959918 scopus 로고    scopus 로고
    • Antiviral therapy: Inhibition of Hepatitis C Virus expression by RNA interference directed against the NS5B region of the viral genome
    • PMID: 17786145
    • Trejo-Avila L, Elizondo-González R, Trujillo-Murillo KDC, Zapata-Benavides P, Rodríguez-Padilla C, et al. (n.d.) Antiviral therapy: inhibition of Hepatitis C Virus expression by RNA interference directed against the NS5B region of the viral genome. Ann Hepatol 6: 174-180. PMID: 17786145
    • Ann Hepatol , vol.6 , pp. 174-180
    • Trejo-Avila, L.1    Elizondo-González, R.2    Trujillo-Murillo, K.D.C.3    Zapata-Benavides, P.4    Rodríguez-Padilla, C.5
  • 48
    • 33750365012 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus gene expression by small interfering RNAs using a tri-cistronic full-length viral replicon and a transient mouse model
    • PMID: 16979254
    • Kim M, Shin D, Kim SI, Park M (2006) Inhibition of hepatitis C virus gene expression by small interfering RNAs using a tri-cistronic full-length viral replicon and a transient mouse model. Virus Res 122: 1-10. PMID: 16979254
    • (2006) Virus Res , vol.122 , pp. 1-10
    • Kim, M.1    Shin, D.2    Kim, S.I.3    Park, M.4
  • 49
    • 1642273831 scopus 로고    scopus 로고
    • An algorithm for selection of functional siRNA sequences
    • PMID: 15044091
    • Amarzguioui M, Prydz H (2004) An algorithm for selection of functional siRNA sequences. Biochem Biophys Res Commun 316: 1050-1058. PMID: 15044091
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 1050-1058
    • Amarzguioui, M.1    Prydz, H.2
  • 51
    • 1642346273 scopus 로고    scopus 로고
    • Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
    • PMID: 14769950
    • Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, et al. (2004) Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Res 32: 936-948. PMID: 14769950
    • (2004) Nucleic Acids Res , vol.32 , pp. 936-948
    • Ui-Tei, K.1    Naito, Y.2    Takahashi, F.3    Haraguchi, T.4    Ohki-Hamazaki, H.5
  • 53
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • PMID: 11157775
    • Elbashir SM, Lendeckel W, Tuschl T (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15: 188-200. PMID: 11157775
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 54
    • 85015391748 scopus 로고    scopus 로고
    • HIV-1 Escape From RNAi Antivirals: Yet Another Houdini Action?
    • PMID: 23344078
    • Berkhout B, Das AT (2012) HIV-1 Escape From RNAi Antivirals: Yet Another Houdini Action? Mol Ther Nucleic Acids 1: e26. doi: 10.1038/mtna.2012.22 PMID: 23344078
    • (2012) Mol Ther Nucleic Acids , vol.1 , pp. e26
    • Berkhout, B.1    Das, A.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.