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Volumn 43, Issue 2, 2005, Pages 225-234

Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors

Author keywords

HCV; HuR; PSMA7; RNAi; siRNA; UTR

Indexed keywords

HU ANTIGEN R; PROTEASOME; PROTEOSOME ALPHA SUBUNIT 7; RETROVIRUS VECTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

EID: 21844438516     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.02.046     Document Type: Article
Times cited : (98)

References (33)
  • 1
    • 0033920304 scopus 로고    scopus 로고
    • Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo
    • A.A. Kolykhalov, K. Mihalik, S.M. Feinstone, and C.M. Rice Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo J Virol 74 2000 2046 2051
    • (2000) J Virol , vol.74 , pp. 2046-2051
    • Kolykhalov, A.A.1    Mihalik, K.2    Feinstone, S.M.3    Rice, C.M.4
  • 2
    • 0035193027 scopus 로고    scopus 로고
    • Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation
    • M. Krüger, C. Beger, P.J. Welch, J.R. Barber, M.P. Manns, and F. Wong-Staal Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation Mol Cell Biol 21 2001 8357 8364
    • (2001) Mol Cell Biol , vol.21 , pp. 8357-8364
    • Krüger, M.1    Beger, C.2    Welch, P.J.3    Barber, J.R.4    Manns, M.P.5    Wong-Staal, F.6
  • 3
    • 0034746363 scopus 로고    scopus 로고
    • The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR
    • J.L. Dean, R. Wait, K.R. Mahtani, G. Sully, A.R. Clark, and J. Saklatvala The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR Mol Cell Biol 21 2001 721 730
    • (2001) Mol Cell Biol , vol.21 , pp. 721-730
    • Dean, J.L.1    Wait, R.2    Mahtani, K.R.3    Sully, G.4    Clark, A.R.5    Saklatvala, J.6
  • 4
    • 0029873536 scopus 로고    scopus 로고
    • Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
    • W.J. Ma, S. Cheng, C. Campbell, A. Wright, and H. Furneaux Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein J Biol Chem 271 1996 8144 8151
    • (1996) J Biol Chem , vol.271 , pp. 8144-8151
    • Ma, W.J.1    Cheng, S.2    Campbell, C.3    Wright, A.4    Furneaux, H.5
  • 5
    • 0035266295 scopus 로고    scopus 로고
    • HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3′ untranslated regions of cytokine and angiogenic factor mRNAs
    • L.B. Nabors, G.Y. Gillespie, L. Harkins, and P.H. King HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3′ untranslated regions of cytokine and angiogenic factor mRNAs Cancer Res 61 2001 2154 2161
    • (2001) Cancer Res , vol.61 , pp. 2154-2161
    • Nabors, L.B.1    Gillespie, G.Y.2    Harkins, L.3    King, P.H.4
  • 6
    • 0034284997 scopus 로고    scopus 로고
    • HuR, a protein implicated in oncogene and growth factor mRNA decay, binds to the 3′ ends of hepatitis C virus RNA of both polarities
    • K. Spangberg, L. Wiklund, and S. Schwartz HuR, a protein implicated in oncogene and growth factor mRNA decay, binds to the 3′ ends of hepatitis C virus RNA of both polarities Virology 274 2000 378 390
    • (2000) Virology , vol.274 , pp. 378-390
    • Spangberg, K.1    Wiklund, L.2    Schwartz, S.3
  • 8
    • 0030933006 scopus 로고    scopus 로고
    • Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay
    • V.E. Myer, X.C. Fan, and J.A. Steitz Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay EMBO J 16 1997 2130 2139
    • (1997) EMBO J , vol.16 , pp. 2130-2139
    • Myer, V.E.1    Fan, X.C.2    Steitz, J.A.3
  • 9
    • 0030803671 scopus 로고    scopus 로고
    • AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation
    • X.C. Fan, V.E. Myer, and J.A. Steitz AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation Genes Dev 11 1997 2557 2568
    • (1997) Genes Dev , vol.11 , pp. 2557-2568
    • Fan, X.C.1    Myer, V.E.2    Steitz, J.A.3
  • 11
    • 0028500582 scopus 로고
    • RNA-mediated virus resistance in transgenic plants: Exploitation of a cellular pathway possibly involved in RNA degradation
    • W.G. Dougherty, J.A. Lindbo, H.A. Smith, T.D. Parks, S. Swaney, and W.M. Proebsting RNA-mediated virus resistance in transgenic plants: exploitation of a cellular pathway possibly involved in RNA degradation Mol Plant Microbe Interact 7 1994 544 552
    • (1994) Mol Plant Microbe Interact , vol.7 , pp. 544-552
    • Dougherty, W.G.1    Lindbo, J.A.2    Smith, H.A.3    Parks, T.D.4    Swaney, S.5    Proebsting, W.M.6
  • 12
    • 0034673645 scopus 로고    scopus 로고
    • A genetic link between co-suppression and RNA interference in C. elegans
    • R.F. Ketting, and R.H. Plasterk A genetic link between co-suppression and RNA interference in C. elegans Nature 404 2000 296 298
    • (2000) Nature , vol.404 , pp. 296-298
    • Ketting, R.F.1    Plasterk, R.H.2
  • 13
    • 0034716907 scopus 로고    scopus 로고
    • Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
    • P. Mourrain, C. Beclin, T. Elmayan, F. Feuerbach, C. Godon, and J.B. Morel Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance Cell 101 2000 533 542
    • (2000) Cell , vol.101 , pp. 533-542
    • Mourrain, P.1    Beclin, C.2    Elmayan, T.3    Feuerbach, F.4    Godon, C.5    Morel, J.B.6
  • 14
    • 3643145804 scopus 로고    scopus 로고
    • Initiation and maintenance of virus-induced gene silencing
    • M.T. Ruiz, O. Voinnet, and D.C. Baulcombe Initiation and maintenance of virus-induced gene silencing Plant Cell 10 1998 937 946
    • (1998) Plant Cell , vol.10 , pp. 937-946
    • Ruiz, M.T.1    Voinnet, O.2    Baulcombe, D.C.3
  • 15
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 16
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 17
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • G.J. Hannon RNA interference Nature 418 2002 244 251
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 18
    • 10744230911 scopus 로고    scopus 로고
    • Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
    • T. Yokota, N. Sakamoto, N. Enomoto, Y. Tanabe, M. Miyagishi, and S. Maekawa Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs EMBO Rep 4 2003 602 608
    • (2003) EMBO Rep , vol.4 , pp. 602-608
    • Yokota, T.1    Sakamoto, N.2    Enomoto, N.3    Tanabe, Y.4    Miyagishi, M.5    Maekawa, S.6
  • 19
    • 0344321890 scopus 로고    scopus 로고
    • RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
    • J.A. Wilson, S. Jayasena, A. Khvorova, S. Sabatinos, I.G. Rodrigue-Gervais, and S. Arya RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells Proc Natl Acad Sci USA 100 2003 2783 2788
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2783-2788
    • Wilson, J.A.1    Jayasena, S.2    Khvorova, A.3    Sabatinos, S.4    Rodrigue-Gervais, I.G.5    Arya, S.6
  • 20
    • 1842584178 scopus 로고    scopus 로고
    • Interfering with hepatitis C virus RNA replication
    • G. Randall, and C.M. Rice Interfering with hepatitis C virus RNA replication Virus Res 102 2004 19 25
    • (2004) Virus Res , vol.102 , pp. 19-25
    • Randall, G.1    Rice, C.M.2
  • 21
    • 0037452625 scopus 로고    scopus 로고
    • Interference of hepatitis C virus RNA replication by short interfering RNAs
    • S.B. Kapadia, A. Brideau-Andersen, and F.V. Chisari Interference of hepatitis C virus RNA replication by short interfering RNAs Proc Natl Acad Sci USA 100 2003 2014 2018
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2014-2018
    • Kapadia, S.B.1    Brideau-Andersen, A.2    Chisari, F.V.3
  • 22
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • S.M. Elbashir, W. Lendeckel, and T. Tuschl RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev 15 2001 188 200
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 23
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • S.M. Elbashir, J. Martinez, A. Patkaniowska, W. Lendeckel, and T. Tuschl Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate EMBO J 20 2001 6877 6888
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 24
    • 7044269394 scopus 로고    scopus 로고
    • Polypyrimidine tract-binding protein (PTB) inhibits hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation, but does not affect HCV replication
    • J.J.W. Tischendorf, C. Beger, M. Korf, M.P. Manns, and M. Krüger Polypyrimidine tract-binding protein (PTB) inhibits hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation, but does not affect HCV replication Arch Virol 149 2004 1955 1970
    • (2004) Arch Virol , vol.149 , pp. 1955-1970
    • Tischendorf, J.J.W.1    Beger, C.2    Korf, M.3    Manns, M.P.4    Krüger, M.5
  • 25
  • 26
    • 12144289381 scopus 로고    scopus 로고
    • Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
    • J. Kronke, R. Kittler, F. Buchholz, M.P. Windisch, T. Pietschmann, and R. Bartenschlager Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs J Virol 78 2004 3436 3446
    • (2004) J Virol , vol.78 , pp. 3436-3446
    • Kronke, J.1    Kittler, R.2    Buchholz, F.3    Windisch, M.P.4    Pietschmann, T.5    Bartenschlager, R.6
  • 27
    • 0034623002 scopus 로고    scopus 로고
    • Human la antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation
    • N. Ali, G.J. Pruijn, D.J. Kenan, J.D. Keene, and A. Siddiqui Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation J Biol Chem 275 2000 27531 27540
    • (2000) J Biol Chem , vol.275 , pp. 27531-27540
    • Ali, N.1    Pruijn, G.J.2    Kenan, D.J.3    Keene, J.D.4    Siddiqui, A.5
  • 28
    • 0029166747 scopus 로고
    • Interaction of polypyrimidine tract-binding protein with the 5′ noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation
    • N. Ali, and A. Siddiqui Interaction of polypyrimidine tract-binding protein with the 5′ noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation J Virol 69 1995 6367 6375
    • (1995) J Virol , vol.69 , pp. 6367-6375
    • Ali, N.1    Siddiqui, A.2
  • 29
    • 0033559870 scopus 로고    scopus 로고
    • HnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3′NTR of the HCV RNA genome
    • R.R. Gontarek, L.L. Gutshall, K.M. Herold, J. Tsai, G.M. Sathe, and J. Mao hnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3′NTR of the HCV RNA genome Nucleic Acids Res 27 1999 1457 1463
    • (1999) Nucleic Acids Res , vol.27 , pp. 1457-1463
    • Gontarek, R.R.1    Gutshall, L.L.2    Herold, K.M.3    Tsai, J.4    Sathe, G.M.5    Mao, J.6
  • 30
    • 1542330798 scopus 로고    scopus 로고
    • Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus
    • J. Zhang, O. Yamada, T. Sakamoto, H. Yoshida, T. Iwai, and Y. Matsushita Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus Virology 320 2004 135 143
    • (2004) Virology , vol.320 , pp. 135-143
    • Zhang, J.1    Yamada, O.2    Sakamoto, T.3    Yoshida, H.4    Iwai, T.5    Matsushita, Y.6
  • 31
    • 10644229240 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity
    • Y.L. Khu, Y.J. Tan, S.G. Lim, W. Hong, and P.Y. Goh Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity Biochem J 384 2004 401 409
    • (2004) Biochem J , vol.384 , pp. 401-409
    • Khu, Y.L.1    Tan, Y.J.2    Lim, S.G.3    Hong, W.4    Goh, P.Y.5
  • 32
    • 0029986179 scopus 로고    scopus 로고
    • Proteasome complex as a potential cellular target of hepatitis B virus X protein
    • J. Huang, J. Kwong, E.C. Sun, and T.J. Liang Proteasome complex as a potential cellular target of hepatitis B virus X protein J Virol 70 1996 5582 5591
    • (1996) J Virol , vol.70 , pp. 5582-5591
    • Huang, J.1    Kwong, J.2    Sun, E.C.3    Liang, T.J.4
  • 33
    • 0032431026 scopus 로고    scopus 로고
    • HNS, a nuclear-cytoplasmic shuttling sequence in HuR
    • X.C. Fan, and J.A. Steitz HNS, a nuclear-cytoplasmic shuttling sequence in HuR Proc Natl Acad Sci USA 95 1998 15293 15298
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15293-15298
    • Fan, X.C.1    Steitz, J.A.2


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