Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood-brain barrier after traumatic brain injury in mice

Neuroscience

Volumn 291, Issue , 2015, Pages 26-36

  Tao, X ^a   Chen, X ^a   Hao, S ^a   Hou, Z ^a   Lu, T ^a   Sun, M ^b   Liu, B ^a,b,c,d,e  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^d GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^e Beijing Key Laboratory of Central Nervous System Injury   (China)

Author keywords

Blood brain barrier; Brain edema; NF B; Poly(ADP ribose) polymerase; Traumatic brain injury

Indexed keywords

BETA1 INTEGRIN; COLLAGEN TYPE 4; EVANS BLUE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LAMININ; MYELOPEROXIDASE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OCCLUDIN; MMP9 PROTEIN, MOUSE; N-(OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)-N,N-DIMETHYLACETAMIDE HYDROCHLORIDE; NEUROPROTECTIVE AGENT; OCLN PROTEIN, MOUSE; PHENANTHRENE DERIVATIVE;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN CONTUSION; BRAIN EDEMA; BRAIN NECROSIS; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME ACTIVATION; ENZYME INHIBITION; MALE; MOUSE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SHAM PROCEDURE; TRAUMATIC BRAIN INJURY; UPREGULATION; WATER CONTENT; ANIMAL; BAGG ALBINO MOUSE; BRAIN; BRAIN INJURIES; CAPILLARY PERMEABILITY; CELL DEATH; DISEASE MODEL; DRUG EFFECTS; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN EDEMA; BRAIN INJURIES; CAPILLARY PERMEABILITY; CELL DEATH; DISEASE MODELS, ANIMAL; MALE; MATRIX METALLOPROTEINASE 9; MICE, INBRED BALB C; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OCCLUDIN; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; POLY(ADP-RIBOSE) POLYMERASES; RANDOM ALLOCATION;

EID: 84923239468     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.01.070     Document Type: Article

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