Cysteinyl-leukotriene receptor antagonist montelukast decreases blood-brain barrier permeability but does not prevent oedema formation in traumatic brain injury

Brain Injury

Volumn 23, Issue 6, 2009, Pages 577-584

  Biber, Necat ^a   Toklu, Hale Z ^b   Solakoglu, Seyhun ^c   Gultomruk, Mine ^c   Hakan, Tayfun ^a   Berkman, Zafer ^a   Gul Dulger, F ^b  

^a Haydarpa a Numune Research and Education Hospital   (Turkey)

^b MARMARA UNIVERSITY   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Antioxidant; Blood brain barrier; Brain injury; Closed head; Cysteinyl leukotriene; Montelukast; Neutrophil; Oedema; Trauma

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); EVANS BLUE; GLUTATHIONE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MALONALDEHYDE; MONTELUKAST; MYELOPEROXIDASE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN TISSUE; BRAIN WATER; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRAVASATION; HISTOPATHOLOGY; LIPID PEROXIDATION; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERMEABILITY BARRIER; RAT; SPRAGUE DAWLEY RAT; TRAUMATIC BRAIN INJURY; WATER CONTENT;

EID: 67650602967     PISSN: 02699052     EISSN: 1362301X     Source Type: Journal    
DOI: 10.1080/02699050902926317     Document Type: Article

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