Neuroprotective mechanism of taurine due to up-regulating calpastatin and down-regulating calpain and caspase-3 during focal cerebral ischemia

Cellular and Molecular Neurobiology

Volumn 28, Issue 4, 2008, Pages 593-611

  Sun, Ming ^a   Xu, Chao ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Calpain; Calpastatin; Caspase 3; Focal cerebral ischemia; Neuroprotection; Taurine

Indexed keywords

ALPHAII SPECTRIN; CALPAIN 1; CALPAIN 2; CALPASTATIN; CASPASE 3; FODRIN; MICROTUBULE ASSOCIATED PROTEIN 1; TAURINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN LEVEL; BRAIN NERVE CELL; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CALCIUM-BINDING PROTEINS; CALPAIN; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; MALE; MICROFILAMENT PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; TAURINE; UP-REGULATION; VESICULAR TRANSPORT PROTEINS;

RATTUS;

EID: 43049097164     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-007-9183-8     Document Type: Article

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